IMP
Process View
b cell lineage commitment
The process in which a lymphoid progenitor cell becomes committed to become any type of B cell.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "b cell lineage commitment"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Trp53 | transformation related protein 53 | 1.000 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.990 | ||
| Pten | phosphatase and tensin homolog | 0.960 | ||
| Igh | immunoglobulin heavy chain complex | 0.739 | ||
| Cd19 | CD19 antigen | 0.712 | ||
| Rag1 | recombination activating gene 1 | 0.640 | ||
| Bax | BCL2-associated X protein | 0.567 | Mouse | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.482 | ||
| Kit | kit oncogene | 0.289 | ||
| Apc | adenomatosis polyposis coli | 0.268 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.198 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.194 | ||
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.167 | ||
| Tcrb | T-cell receptor beta chain | 0.156 | ||
| Tcra | T-cell receptor alpha chain | 0.133 | ||
| Tcrd | T-cell receptor delta chain | 0.133 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.132 | ||
| Brca1 | breast cancer 1 | 0.109 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.089 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.079 | ||
| Trp73 | transformation related protein 73 | 0.061 | Mouse | |
| Foxp3 | forkhead box P3 | 0.057 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.057 | ||
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.047 | ||
| Huwe1 | HECT, UBA and WWE domain containing 1 | 0.044 | ||
| Il2rg | interleukin 2 receptor, gamma chain | 0.044 | ||
| Trp63 | transformation related protein 63 | 0.043 | Mouse | |
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.042 | ||
| Runx1 | runt related transcription factor 1 | 0.041 | ||
| Ifng | interferon gamma | 0.041 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.038 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.038 | ||
| Braf | Braf transforming gene | 0.036 | ||
| Tcf3 | transcription factor 3 | 0.035 | Human | |
| Rara | retinoic acid receptor, alpha | 0.033 | ||
| Card11 | caspase recruitment domain family, member 11 | 0.029 | ||
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.029 | ||
| Sfn | stratifin | 0.028 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.027 | ||
| Rxra | retinoid X receptor alpha | 0.026 | ||
| Esr1 | estrogen receptor 1 (alpha) | 0.026 | ||
| Hr | hairless | 0.025 | ||
| Atm | ataxia telangiectasia mutated homolog (human) | 0.023 | ||
| Bak1 | BCL2-antagonist/killer 1 | 0.023 | Mouse | |
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.022 | ||
| Rb1 | retinoblastoma 1 | 0.020 | ||
| Ep300 | E1A binding protein p300 | 0.020 | ||
| Cd79a | CD79A antigen (immunoglobulin-associated alpha) | 0.017 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.016 | ||
| Yap1 | yes-associated protein 1 | 0.016 | ||
| Lyst | lysosomal trafficking regulator | 0.016 | ||
| Mll1 | myeloid/lymphoid or mixed-lineage leukemia 1 | 0.015 | ||
| Cdk4 | cyclin-dependent kinase 4 | 0.014 | ||
| Cdkn2a | cyclin-dependent kinase inhibitor 2A | 0.014 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.013 | ||
| Foxn1 | forkhead box N1 | 0.013 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.013 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.012 | ||
| Ccnd1 | cyclin D1 | 0.012 | ||
| Smarcd1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.012 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.012 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.011 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.011 | ||
| Bcl2l1 | BCL2-like 1 | 0.011 | Mouse | |
| Aicda | activation-induced cytidine deaminase | 0.010 |