IMP

Process View

Mus musculus

5 genes annotated in mouse

negative regulation of cyclic nucleotide metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of cyclic nucleotide metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of cyclic nucleotide metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Drd2	dopamine receptor D2	0.871	Human Rat
Cckbr	cholecystokinin B receptor	0.596
Oprm1	opioid receptor, mu 1	0.581	Rat
Adrb1	adrenergic receptor, beta 1	0.434	Mouse
Gabbr2	gamma-aminobutyric acid (GABA) B receptor, 2	0.327
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.267	Mouse
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.214	Mouse
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.214
Pnpla2	patatin-like phospholipase domain containing 2	0.201
Crhr1	corticotropin releasing hormone receptor 1	0.142
Cnr1	cannabinoid receptor 1 (brain)	0.118
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.111	Mouse
Pparg	peroxisome proliferator activated receptor gamma	0.107
Edn1	endothelin 1	0.096
Rs1	retinoschisis (X-linked, juvenile) 1 (human)	0.094
Sstr4	somatostatin receptor 4	0.089
Npy2r	neuropeptide Y receptor Y2	0.077
Oprd1	opioid receptor, delta 1	0.074
Htr5a	5-hydroxytryptamine (serotonin) receptor 5A	0.073	Mouse
Vegfa	vascular endothelial growth factor A	0.065
Oprk1	opioid receptor, kappa 1	0.065
Nos1	nitric oxide synthase 1, neuronal	0.063
Ryr3	ryanodine receptor 3	0.051
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.049
Sstr1	somatostatin receptor 1	0.046
Hrh1	histamine receptor H1	0.044
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.044
Kcnk3	potassium channel, subfamily K, member 3	0.043
Pde6a	phosphodiesterase 6A, cGMP-specific, rod, alpha	0.042	Mouse
Npy5r	neuropeptide Y receptor Y5	0.041
Tectb	tectorin beta	0.040
Drd4	dopamine receptor D4	0.040	Human
Kl	klotho	0.039
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.038
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.038
Rrh	retinal pigment epithelium derived rhodopsin homolog	0.037
Grm1	glutamate receptor, metabotropic 1	0.036
Vip	vasoactive intestinal polypeptide	0.035
Shc3	src homology 2 domain-containing transforming protein C3	0.032
Cer1	cerberus 1 homolog (Xenopus laevis)	0.030
Cntn4	contactin 4	0.029
Adrb3	adrenergic receptor, beta 3	0.028	Mouse
Nrp1	neuropilin 1	0.027
Kcne2	potassium voltage-gated channel, Isk-related subfamily, gene 2	0.027
Drd3	dopamine receptor D3	0.027	Human Rat
Olfr1509	olfactory receptor 1509	0.027
Mitf	microphthalmia-associated transcription factor	0.027
Cox8c	cytochrome c oxidase, subunit VIIIc	0.025
Mc3r	melanocortin 3 receptor	0.025
Epas1	endothelial PAS domain protein 1	0.025
Grm2	glutamate receptor, metabotropic 2	0.024
Rcvrn	recoverin	0.024
Gnrh1	gonadotropin releasing hormone 1	0.024
Nxph2	neurexophilin 2	0.023
Mas1	MAS1 oncogene	0.023
Prlhr	prolactin releasing hormone receptor	0.023
Ppyr1	pancreatic polypeptide receptor 1	0.023
Gjd2	gap junction protein, delta 2	0.023
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.022
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.022
Adrb2	adrenergic receptor, beta 2	0.022	Mouse
Opn1sw	opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)	0.021
Crygs	crystallin, gamma S	0.021
Trpc5	transient receptor potential cation channel, subfamily C, member 5	0.021
Acvr1	activin A receptor, type 1	0.021
Gpr12	G-protein coupled receptor 12	0.020
Slc12a1	solute carrier family 12, member 1	0.020
Musk	muscle, skeletal, receptor tyrosine kinase	0.020
Grid1	glutamate receptor, ionotropic, delta 1	0.020
Col19a1	collagen, type XIX, alpha 1	0.020
ND6	NADH dehydrogenase subunit 6	0.020
Epha6	Eph receptor A6	0.020
Sncb	synuclein, beta	0.019
Ece1	endothelin converting enzyme 1	0.019
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.019
Crx	cone-rod homeobox containing gene	0.019
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.019
Sprr2f	small proline-rich protein 2F	0.018
Ednrb	endothelin receptor type B	0.018	Mouse
Prph2	peripherin 2	0.017
Fshb	follicle stimulating hormone beta	0.017
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.017
Col4a3	collagen, type IV, alpha 3	0.017
Hif1a	hypoxia inducible factor 1, alpha subunit	0.017
Grm8	glutamate receptor, metabotropic 8	0.017
Odz1	odd Oz/ten-m homolog 1 (Drosophila)	0.016
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.016
Kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	0.016
Cntn3	contactin 3	0.016
Fam164c	family with sequence similarity 164, member C	0.016
Psg17	pregnancy specific glycoprotein 17	0.016
Ltk	leukocyte tyrosine kinase	0.016
Gpr83	G protein-coupled receptor 83	0.016
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.015
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.015
Npy1r	neuropeptide Y receptor Y1	0.015
Hand1	heart and neural crest derivatives expressed transcript 1	0.015
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.015
Avp	arginine vasopressin	0.015
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.014
Olfr71	olfactory receptor 71	0.014
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.014
Slc22a6	solute carrier family 22 (organic anion transporter), member 6	0.014
Gad2	glutamic acid decarboxylase 2	0.014
Otog	otogelin	0.013
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.013
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.013
Krt84	keratin 84	0.013
Hcrt	hypocretin	0.013
Sox1	SRY-box containing gene 1	0.013
Acsm2	acyl-CoA synthetase medium-chain family member 2	0.013
Pramel6	preferentially expressed antigen in melanoma like 6	0.013
Chia	chitinase, acidic	0.013
Krt86	keratin 86	0.013
Zfr2	zinc finger RNA binding protein 2	0.012
Kifc2	kinesin family member C2	0.012
Igll1	immunoglobulin lambda-like polypeptide 1	0.012
Prl4a1	prolactin family 4, subfamily a, member 1	0.012
Rp1	retinitis pigmentosa 1 (human)	0.012
Gpr3	G-protein coupled receptor 3	0.012
3110047P20Rik	RIKEN cDNA 3110047P20 gene	0.012
Olfr1264	olfactory receptor 1264	0.012
Npy6r	neuropeptide Y receptor Y6	0.012
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.012
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.012	Mouse
Csmd1	CUB and Sushi multiple domains 1	0.012
Enam	enamelin	0.012
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.012
Gpr33	G protein-coupled receptor 33	0.011
Tyr	tyrosinase	0.011
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.011
Rgs8	regulator of G-protein signaling 8	0.011
Ntsr2	neurotensin receptor 2	0.011
Ednra	endothelin receptor type A	0.011
Ppp1r1b	protein phosphatase 1, regulatory (inhibitor) subunit 1B	0.011
Galr2	galanin receptor 2	0.011
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.011
Krt32	keratin 32	0.011
Dlx6	distal-less homeobox 6	0.011
Pex5l	peroxisomal biogenesis factor 5-like	0.011
Rgs4	regulator of G-protein signaling 4	0.010
Gabrg3	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3	0.010
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.010
Pgr	progesterone receptor	0.010
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.010
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.010	Mouse
Rgs6	regulator of G-protein signaling 6	0.010
Sult4a1	sulfotransferase family 4A, member 1	0.010