IMP

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Mus musculus

8 genes annotated in mouse

establishment of monopolar cell polarity

The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "establishment of monopolar cell polarity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "establishment of monopolar cell polarity" (in gray)

Name	Description	Probability	Func Analog Organism
Dvl2	dishevelled 2, dsh homolog (Drosophila)	1.000	Fly
Vangl2	vang-like 2 (van gogh, Drosophila)	0.999
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.995	Fly
Vangl1	vang-like 1 (van gogh, Drosophila)	0.991
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.958	Fly
Neurod1	neurogenic differentiation 1	0.924	Mouse
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.896
Pax6	paired box gene 6	0.878
Neurog2	neurogenin 2	0.826	Mouse
Vegfa	vascular endothelial growth factor A	0.691
Ldb3	LIM domain binding 3	0.527
Neurod4	neurogenic differentiation 4	0.494	Mouse
Sox11	SRY-box containing gene 11	0.356
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.355	Fly
Itga3	integrin alpha 3	0.341
Lmx1b	LIM homeobox transcription factor 1 beta	0.324
Sox2	SRY-box containing gene 2	0.303
Emx1	empty spiracles homolog 1 (Drosophila)	0.264
Ptk7	PTK7 protein tyrosine kinase 7	0.262
Prkcz	protein kinase C, zeta	0.239	Mouse
Dab1	disabled homolog 1 (Drosophila)	0.191
Cdh23	cadherin 23 (otocadherin)	0.189	Fly
Otx2	orthodenticle homolog 2 (Drosophila)	0.179
Mecom	MDS1 and EVI1 complex locus	0.151
Shh	sonic hedgehog	0.137
Lamb1	laminin B1	0.136
Gdnf	glial cell line derived neurotrophic factor	0.133
Onecut1	one cut domain, family member 1	0.131
Neurog3	neurogenin 3	0.118	Mouse
Nkd1	naked cuticle 1 homolog (Drosophila)	0.107
Myh10	myosin, heavy polypeptide 10, non-muscle	0.101
Gata1	GATA binding protein 1	0.098
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.098
Zeb1	zinc finger E-box binding homeobox 1	0.090
Tlx3	T-cell leukemia, homeobox 3	0.076
Ptk2	PTK2 protein tyrosine kinase 2	0.073
Dact3	dapper homolog 3, antagonist of beta-catenin (xenopus)	0.072
Ina	internexin neuronal intermediate filament protein, alpha	0.072
Ush1g	Usher syndrome 1G homolog (human)	0.072
Insm1	insulinoma-associated 1	0.071
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.067
Pou4f3	POU domain, class 4, transcription factor 3	0.067
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.066
Foxg1	forkhead box G1	0.065
Pou4f2	POU domain, class 4, transcription factor 2	0.060
Tcf3	transcription factor 3	0.059
Atoh7	atonal homolog 7 (Drosophila)	0.056	Mouse
Pou3f3	POU domain, class 3, transcription factor 3	0.056
Zic3	zinc finger protein of the cerebellum 3	0.054
Prph2	peripherin 2	0.053
Nhlh1	nescient helix loop helix 1	0.051	Mouse
Foxa2	forkhead box A2	0.049
Sim2	single-minded homolog 2 (Drosophila)	0.049
Hsf1	heat shock factor 1	0.049
Arx	aristaless related homeobox	0.048
Kiss1	KiSS-1 metastasis-suppressor	0.048
Cldn3	claudin 3	0.047
Plcg2	phospholipase C, gamma 2	0.045
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.044
Srrm4	serine/arginine repetitive matrix 4	0.042
Msx1	homeobox, msh-like 1	0.038
Gpc3	glypican 3	0.036
Foxf2	forkhead box F2	0.034	Mouse
Nphs2	nephrosis 2 homolog, podocin (human)	0.034
Celsr1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.034
Cd151	CD151 antigen	0.032
Ptf1a	pancreas specific transcription factor, 1a	0.031	Mouse
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.031
Tbx2	T-box 2	0.031
Snai1	snail homolog 1 (Drosophila)	0.030
Gsc	goosecoid homeobox	0.030
Prkcb	protein kinase C, beta	0.029
Foxj1	forkhead box J1	0.029
Cd19	CD19 antigen	0.029
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.029
Sav1	salvador homolog 1 (Drosophila)	0.029
Mks1	Meckel syndrome, type 1	0.028
Pitx1	paired-like homeodomain transcription factor 1	0.028
Smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.027
Pdx1	pancreatic and duodenal homeobox 1	0.027
Arrb2	arrestin, beta 2	0.027
Col4a1	collagen, type IV, alpha 1	0.026
Lep	leptin	0.026
Dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.026
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.026
Hoxb4	homeobox B4	0.026
Tcf21	transcription factor 21	0.025
Irs3	insulin receptor substrate 3	0.025
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.024
Akt1	thymoma viral proto-oncogene 1	0.024	Mouse
Kif3a	kinesin family member 3A	0.024
Gnrh1	gonadotropin releasing hormone 1	0.023
Vcan	versican	0.023
Noto	notochord homolog (Xenopus laevis)	0.023
Gpsm3	G-protein signalling modulator 3 (AGS3-like, C. elegans)	0.023
Tgif2	TGFB-induced factor homeobox 2	0.023
Lhx6	LIM homeobox protein 6	0.023
Igh	immunoglobulin heavy chain complex	0.022
Gli2	GLI-Kruppel family member GLI2	0.022
Cnn1	calponin 1	0.022
Pitx3	paired-like homeodomain transcription factor 3	0.022
Ikzf1	IKAROS family zinc finger 1	0.021
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.021
Zic4	zinc finger protein of the cerebellum 4	0.021
Wwc1	WW, C2 and coiled-coil domain containing 1	0.021
Wnt7a	wingless-related MMTV integration site 7A	0.021
Lhx5	LIM homeobox protein 5	0.021
Cdh4	cadherin 4	0.020
Rgnef	Rho-guanine nucleotide exchange factor	0.020
Fam64a	family with sequence similarity 64, member A	0.019
Evx1	even skipped homeotic gene 1 homolog	0.019
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.019
Yap1	yes-associated protein 1	0.019
Fzd6	frizzled homolog 6 (Drosophila)	0.019	Fly
Pcdh12	protocadherin 12	0.019
Pou3f2	POU domain, class 3, transcription factor 2	0.019
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.019
Prx	periaxin	0.018
Cxadr	coxsackie virus and adenovirus receptor	0.018
Neurog1	neurogenin 1	0.018	Mouse
Pvrl3	poliovirus receptor-related 3	0.018
Ldb1	LIM domain binding 1	0.018
Prkce	protein kinase C, epsilon	0.018
Myo15	myosin XV	0.018
Nefm	neurofilament, medium polypeptide	0.017
Fjx1	four jointed box 1 (Drosophila)	0.017	Fly
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.017
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.017
Tead2	TEA domain family member 2	0.017
Igfbpl1	insulin-like growth factor binding protein-like 1	0.017
Ebf2	early B-cell factor 2	0.016
Wnk2	WNK lysine deficient protein kinase 2	0.016
Iqcb1	IQ calmodulin-binding motif containing 1	0.016
Sox1	SRY-box containing gene 1	0.016
Pitx2	paired-like homeodomain transcription factor 2	0.016
Foxc2	forkhead box C2	0.016
Bmp7	bone morphogenetic protein 7	0.015
Homer1	homer homolog 1 (Drosophila)	0.015
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.015
Myo6	myosin VI	0.015
Ager	advanced glycosylation end product-specific receptor	0.015
Shox2	short stature homeobox 2	0.015
Nkx2-1	NK2 homeobox 1	0.015
Prox1	prospero-related homeobox 1	0.015
Hes2	hairy and enhancer of split 2 (Drosophila)	0.015
Inhbb	inhibin beta-B	0.015
Nfib	nuclear factor I/B	0.015
Mip	major intrinsic protein of eye lens fiber	0.015
Atoh1	atonal homolog 1 (Drosophila)	0.014	Mouse
Invs	inversin	0.014
Lgr5	leucine rich repeat containing G protein coupled receptor 5	0.014
Fzd3	frizzled homolog 3 (Drosophila)	0.014	Fly
Angptl2	angiopoietin-like 2	0.014
Myo7a	myosin VIIA	0.014
Fgf15	fibroblast growth factor 15	0.014
Dll1	delta-like 1 (Drosophila)	0.014
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.014
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.014
Tcfap2c	transcription factor AP-2, gamma	0.014
Shank2	SH3/ankyrin domain gene 2	0.014
Lmo1	LIM domain only 1	0.013
Akt2	thymoma viral proto-oncogene 2	0.013	Mouse
Vhl	von Hippel-Lindau tumor suppressor	0.013
Pou3f1	POU domain, class 3, transcription factor 1	0.013
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.013
Hmx1	H6 homeobox 1	0.013
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.013
Plcb3	phospholipase C, beta 3	0.013
Tekt2	tektin 2	0.013
Lmo2	LIM domain only 2	0.013
Axin1	axin 1	0.013
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.012
Cplx2	complexin 2	0.012
Dnahc11	dynein, axonemal, heavy chain 11	0.012
Col13a1	collagen, type XIII, alpha 1	0.012
Large	like-glycosyltransferase	0.012
Hand1	heart and neural crest derivatives expressed transcript 1	0.012	Mouse
Dusp9	dual specificity phosphatase 9	0.012
Egfr	epidermal growth factor receptor	0.012
Isl1	ISL1 transcription factor, LIM/homeodomain	0.012
Col12a1	collagen, type XII, alpha 1	0.012
Foxd2	forkhead box D2	0.012
Cd28	CD28 antigen	0.012
Epha2	Eph receptor A2	0.011
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.011
Edn3	endothelin 3	0.011
Utf1	undifferentiated embryonic cell transcription factor 1	0.011
Bcl2	B-cell leukemia/lymphoma 2	0.011
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.011
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.011
Cdh16	cadherin 16	0.011
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.011
Mllt1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.011
H1fx	H1 histone family, member X	0.011
Foxb1	forkhead box B1	0.011
Trim10	tripartite motif-containing 10	0.011
Hes5	hairy and enhancer of split 5 (Drosophila)	0.011
Igf1r	insulin-like growth factor I receptor	0.011
Ptprb	protein tyrosine phosphatase, receptor type, B	0.011
Col6a3	collagen, type VI, alpha 3	0.011
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.010
Tcf15	transcription factor 15	0.010
Pax9	paired box gene 9	0.010
Irx1	Iroquois related homeobox 1 (Drosophila)	0.010
Zic2	zinc finger protein of the cerebellum 2	0.010
Pbx1	pre B-cell leukemia transcription factor 1	0.010
Gdf11	growth differentiation factor 11	0.010
Nkd2	naked cuticle 2 homolog (Drosophila)	0.010
Sfn	stratifin	0.010
Prkca	protein kinase C, alpha	0.010
Crb2	crumbs homolog 2 (Drosophila)	0.010
Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	0.010