IMP

Process View

Rattus norvegicus

11 genes annotated in rat

membrane hyperpolarization

The process in which membrane potential changes in the hyperpolarizing direction from the resting potential, usually from negative to more negative.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "membrane hyperpolarization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "membrane hyperpolarization" (in gray)

Name	Description	Probability	Func Analog Organism
Aqp4	aquaporin 4	0.265
Gria1	glutamate receptor, ionotropic, AMPA 1	0.224
Dlg4	discs, large homolog 4 (Drosophila)	0.222
Fgf14	fibroblast growth factor 14	0.187
Folh1	folate hydrolase 1	0.187
Hpcal4	hippocalcin-like 4	0.179
Dlgap3	discs, large (Drosophila) homolog-associated protein 3	0.179
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.171
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.166
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.137
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.129
Egr3	early growth response 3	0.115
Kcnc2	potassium voltage gated channel, Shaw-related subfamily, member 2	0.100
Chrm5	cholinergic receptor, muscarinic 5	0.099
Scn5a	sodium channel, voltage-gated, type V, alpha subunit	0.096
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.092
Gas7	growth arrest specific 7	0.088
Drd1a	dopamine receptor D1A	0.088
Grin2b	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.085
Ddn	dendrin	0.077
Gabra4	gamma-aminobutyric acid (GABA) A receptor, alpha 4	0.075
Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	0.073
Myo9a	myosin IXA	0.069
Slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.067
Gjb5	gap junction protein, beta 5	0.066
LOC60591	calcium-activated potassium channel beta subunit	0.064
Gja1	gap junction protein, alpha 1	0.063
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.063
Mag	myelin-associated glycoprotein	0.063
Phkg1	phosphorylase kinase, gamma 1	0.062
Mapk3	mitogen activated protein kinase 3	0.061
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.061
Ncan	neurocan	0.060
Olr416	olfactory receptor 416	0.059
Eef2	eukaryotic translation elongation factor 2	0.055
Syn1	synapsin I	0.055
Prkcg	protein kinase C, gamma	0.054	Rat
Ar	androgen receptor	0.054
Dlg2	discs, large homolog 2 (Drosophila)	0.053
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.053	Rat
Abp1	amiloride binding protein 1 (amine oxidase, copper-containing)	0.053
Adora1	adenosine A1 receptor	0.051
Rgs14	regulator of G-protein signaling 14	0.049
Pdyn	prodynorphin	0.049
Hcrtr2	hypocretin (orexin) receptor 2	0.048
Chrna1	cholinergic receptor, nicotinic, alpha 1 (muscle)	0.048
Plcd4	phospholipase C, delta 4	0.046
Sycn	syncollin	0.046
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.044
Mmp7	matrix metallopeptidase 7	0.043
Vcsa1	variable coding sequence A1	0.043
RGD1559748	similar to Palate lung and nasal carcinoma-like protein precursor (Tongue plunc-like protein)	0.042
Sstr5	somatostatin receptor 5	0.040
Sparcl1	SPARC-like 1 (hevin)	0.040
Grik3	glutamate receptor, ionotropic, kainate 3	0.038
Cma1	chymase 1, mast cell	0.038
Shbg	sex hormone binding globulin	0.038
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.037
Nlgn2	neuroligin 2	0.037
Slc1a1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	0.037
Ppard	peroxisome proliferator-activated receptor delta	0.037
Sprr1al	small proline-rich protein 1A-like	0.037
Atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.036
Nfasc	neurofascin	0.036
Gria4	glutamate receptor, ionotrophic, AMPA 4	0.036
Arhgap23	Rho GTPase activating protein 23	0.035
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.035
S100b	S100 calcium binding protein B	0.035
Ppyr1	pancreatic polypeptide receptor 1	0.035
Hk1	hexokinase 1	0.034
Rgs9	regulator of G-protein signaling 9	0.033
Crhr1	corticotropin releasing hormone receptor 1	0.033
Gnb2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.033
Ank2	ankyrin 2, neuronal	0.032
Gnao1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.032
Cnksr2	connector enhancer of kinase suppressor of Ras 2	0.032
Hes2	hairy and enhancer of split 2 (Drosophila)	0.032
Nrxn2	neurexin 2	0.032
Mbp	myelin basic protein	0.031
Rab20	RAB20, member RAS oncogene family	0.030
Nlgn3	neuroligin 3	0.030
Edn1	endothelin 1	0.030
Itpr1	inositol 1,4,5-triphosphate receptor, type 1	0.030
Slc24a2	solute carrier family 24 (sodium/potassium/calcium exchanger), member 2	0.030
RT1-S3	RT1 class Ib, locus S3	0.029
Npy5r	neuropeptide Y receptor Y5	0.029
Sirpa	signal-regulatory protein alpha	0.029
Prph2	peripherin 2	0.029
Pla2g5	phospholipase A2, group V	0.029
Edn2	endothelin 2	0.028
Inha	inhibin alpha	0.028
Accn1	amiloride-sensitive cation channel 1, neuronal	0.028
Musk	muscle, skeletal, receptor tyrosine kinase	0.028
Gja3	gap junction protein, alpha 3	0.028
Olr1493	olfactory receptor gene Olr1493	0.027
Pgc	progastricsin (pepsinogen C)	0.026
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, gamma 1	0.025
Arpp21	cAMP-regulated phosphoprotein 21	0.025
Adrb1	adrenergic, beta-1-, receptor	0.025
Ros1	c-ros oncogene 1 , receptor tyrosine kinase	0.025
Htr2a	5-hydroxytryptamine (serotonin) receptor 2A	0.025	Rat
Fgf5	fibroblast growth factor 5	0.025
Alox5	arachidonate 5-lipoxygenase	0.025
Col4a4	collagen, type IV, alpha 4	0.024
Grin2a	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.024
Gpr12	G protein-coupled receptor 12	0.023
Rab3b	RAB3B, member RAS oncogene family	0.023
Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	0.023
Slc6a17	solute carrier family 6 (neurotransmitter transporter), member 17	0.023
Syt10	synaptotagmin X	0.023
Hes3	hairy and enhancer of split 3 (Drosophila)	0.023
Cpne9	copine family member IX	0.023
Dusp4	dual specificity phosphatase 4	0.023
Myh6	myosin, heavy chain 6, cardiac muscle, alpha	0.023
Adrb3	adrenergic, beta-3-, receptor	0.023	Rat
Syngr2	synaptogyrin 2	0.023
Slc2a13	solute carrier family 2 (facilitated glucose transporter), member 13	0.022
Grm6	glutamate receptor, metabotropic 6	0.022
Umod	uromodulin	0.022
Sstr4	somatostatin receptor 4	0.022
Ptk2b	PTK2B protein tyrosine kinase 2 beta	0.022
Strn	striatin, calmodulin binding protein	0.022
Cd83	CD83 molecule	0.022
Rftn2	raftlin family member 2	0.021
Adam2	ADAM metallopeptidase domain 2	0.021
Epn3	epsin 3	0.021
Sptan1	spectrin, alpha, non-erythrocytic 1	0.021
Tnfsf4	tumor necrosis factor (ligand) superfamily, member 4	0.021
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.021
Kcnt1	potassium channel, subfamily T, member 1	0.021
Ugt2b7	UDP glucuronosyltransferase 2 family, polypeptide B7	0.021
Grifin	galectin-related inter-fiber protein	0.020
Vom2r44	vomeronasal 2 receptor 44	0.020
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform	0.020
Chia	chitinase, acidic	0.020
Celsr3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)	0.020
Nrxn3	neurexin 3	0.020
Ccnd3	cyclin D3	0.020
Asph	aspartate-beta-hydroxylase	0.020
Ccl11	chemokine (C-C motif) ligand 11	0.020
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.020
Lifr	leukemia inhibitory factor receptor alpha	0.020
Cubn	cubilin (intrinsic factor-cobalamin receptor)	0.019
Ptprc	protein tyrosine phosphatase, receptor type, C	0.019
Tas2r126	taste receptor, type 2, member 126	0.019
Slc6a20	solute carrier family 6 (proline IMINO transporter), member 20	0.019
Rph3a	rabphilin 3A	0.019
Sult1d1	sulfotransferase family 1D, member 1	0.019
Cntn1	contactin 1	0.019
Abcd2	ATP-binding cassette, subfamily D (ALD), member 2	0.018
Tbx19	T-box 19	0.018
Ucp1	uncoupling protein 1 (mitochondrial, proton carrier)	0.018
Chrm3	cholinergic receptor, muscarinic 3	0.018
Ceacam11	carcinoembryonic antigen-related cell adhesion molecule 11	0.018
Spata9	spermatogenesis associated 9	0.018
Msx2	msh homeobox 2	0.017
Slc5a5	solute carrier family 5 (sodium iodide symporter), member 5	0.017
Camk4	calcium/calmodulin-dependent protein kinase IV	0.017
Galr1	galanin receptor 1	0.017
RGD1565859	RGD1565859	0.017
Kcnab1	potassium voltage-gated channel, shaker-related subfamily, beta member 1	0.017
Oprd1	opioid receptor, delta 1	0.017
Gpc1	glypican 1	0.017
Ank3	ankyrin 3, node of Ranvier	0.017
Grm2	glutamate receptor, metabotropic 2	0.017
Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	0.017
Gfpt1	glutamine fructose-6-phosphate transaminase 1	0.016
Hr	hairless	0.016
Rgs8	regulator of G-protein signaling 8	0.016
Cap2	CAP, adenylate cyclase-associated protein, 2 (yeast)	0.016
Nrgn	neurogranin	0.016
Agtr1a	angiotensin II receptor, type 1a	0.016
Aplnr	apelin receptor	0.016
Chrna7	cholinergic receptor, nicotinic, alpha 7	0.016
Apba1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.016
Pou3f1	POU class 3 homeobox 1	0.016
Isl2	ISL LIM homeobox 2	0.016
Ocm	oncomodulin	0.016
P2ry4	pyrimidinergic receptor P2Y, G-protein coupled, 4	0.016
Defb4	defensin beta 4	0.015
Gast	gastrin	0.015
Ube2d4	ubiquitin-conjugating enzyme E2D 4	0.015
Lrrc7	leucine rich repeat containing 7	0.015
Sox12	SRY (sex determining region Y)-box 12	0.015
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.015
Tnr	tenascin R	0.015
Abcc8	ATP-binding cassette, subfamily C (CFTR/MRP), member 8	0.015
Trhr	thyrotropin releasing hormone receptor	0.015
Olr226	olfactory receptor 226	0.015
Mocs3	molybdenum cofactor synthesis 3	0.015
Pnmt	phenylethanolamine-N-methyltransferase	0.015
Crhbp	corticotropin releasing hormone binding protein	0.015
Chrm1	cholinergic receptor, muscarinic 1	0.015
Mog	myelin oligodendrocyte glycoprotein	0.015
Pax6	paired box 6	0.015
Gna15	guanine nucleotide binding protein, alpha 15	0.015
Atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.015
Clec11a	C-type lectin domain family 11, member a	0.014
RT1-M4	RT1 class Ib, locus M4	0.014
Cdh17	cadherin 17	0.014
Dlx5	distal-less homeobox 5	0.014
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.014
Slc12a3	solute carrier family 12 (sodium/chloride transporters), member 3	0.014
Ibsp	integrin-binding sialoprotein	0.014
Pygm	phosphorylase, glycogen, muscle	0.014
Necab1	N-terminal EF-hand calcium binding protein 1	0.014
Degs2	degenerative spermatocyte homolog 2, lipid desaturase (Drosophila)	0.014
Accn2	amiloride-sensitive cation channel 2, neuronal	0.014
Gabrr3	gamma-aminobutyric acid (GABA) receptor, rho 3	0.014
Bcan	brevican	0.014
Gabrr1	gamma-aminobutyric acid (GABA) receptor, rho 1	0.014
Cmtm2a	CKLF-like MARVEL transmembrane domain containing 2A	0.014
Prss22	protease, serine, 22	0.014
Fgf10	fibroblast growth factor 10	0.014
Itpka	inositol 1,4,5-trisphosphate 3-kinase A	0.014
Slc6a11	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	0.014
Cpa3	carboxypeptidase A3, mast cell	0.014
Efhd2	EF-hand domain family, member D2	0.014
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.013
Slc1a6	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	0.013
Bace1	beta-site APP cleaving enzyme 1	0.013
Kcnh3	potassium voltage-gated channel, subfamily H (eag-related), member 3	0.013
Fgf7	fibroblast growth factor 7	0.013
Cuzd1	CUB and zona pellucida-like domains 1	0.013
Psp	parotid secretory protein	0.013
Arc	activity-regulated cytoskeleton-associated protein	0.013
Tore	trispanning orphan	0.013
Rho	rhodopsin	0.013
Smad3	SMAD family member 3	0.013
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.013
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.013
Grip1	glutamate receptor interacting protein 1	0.013
Ptpro	protein tyrosine phosphatase, receptor type, O	0.013
Gnb3	guanine nucleotide binding protein (G protein), beta polypeptide 3	0.013
Cartpt	CART prepropeptide	0.013
Sidt1	SID1 transmembrane family, member 1	0.013
Cd46	CD46 molecule, complement regulatory protein	0.012
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.012
Opn1sw	opsin 1 (cone pigments), short-wave-sensitive	0.012
Gpr6	G protein-coupled receptor 6	0.012
Gad2	glutamate decarboxylase 2	0.012
C1ql3	complement component 1, q subcomponent-like 3	0.012
Tlr4	toll-like receptor 4	0.012
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.012
Kcnn1	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1	0.012
Ptgdr	prostaglandin D receptor	0.012
Sox17	SRY (sex determining region Y)-box 17	0.012
Grid2	glutamate receptor, ionotropic, delta 2	0.012
Cacng4	calcium channel, voltage-dependent, gamma subunit 4	0.012
Cxcl2	chemokine (C-X-C motif) ligand 2	0.012
Mobp	myelin-associated oligodendrocyte basic protein	0.012
Clcn1	chloride channel 1	0.012
Stat6	signal transducer and activator of transcription 6	0.012
Rasa2	RAS p21 protein activator 2	0.012
Cdh6	cadherin 6	0.012
Atxn1	ataxin 1	0.012
Hrh3	histamine receptor H3	0.012
Ccr5	chemokine (C-C motif) receptor 5	0.012
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.011
Kl	Klotho	0.011
Adcyap1r1	adenylate cyclase activating polypeptide 1 receptor 1	0.011
Cckbr	cholecystokinin B receptor	0.011
Rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.011
Prp15	proline-rich protein 15	0.011
Rims1	regulating synaptic membrane exocytosis 1	0.011
Kcnk3	potassium channel, subfamily K, member 3	0.011
Lsamp	limbic system-associated membrane protein	0.011
Dgkb	diacylglycerol kinase, beta	0.011
Hnmt	histamine N-methyltransferase	0.011
Cyp2d4	cytochrome P450, family 2, subfamily d, polypeptide 4	0.011
Dgkg	diacylglycerol kinase, gamma	0.011
Sctr	secretin receptor	0.011
A2bp1	ataxin 2 binding protein 1	0.011
Fgfr2	fibroblast growth factor receptor 2	0.011
Ppp2r2c	protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform	0.011
Mc4r	melanocortin 4 receptor	0.011
Pnlip	pancreatic lipase	0.011
Pou3f3	POU class 3 homeobox 3	0.011
Trhr2	thyrotropin releasing hormone receptor 2	0.011
Slit2	slit homolog 2 (Drosophila)	0.011
Prl8a2	prolactin family 8, subfamily a, member 2	0.011
Matk	megakaryocyte-associated tyrosine kinase	0.011
Adcy5	adenylate cyclase 5	0.011
Oprm1	opioid receptor, mu 1	0.011
Stk39	serine/threonine kinase 39, STE20/SPS1 homolog (yeast)	0.011
RGD1560784	similar to RIKEN cDNA B630019K06	0.011
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.011
Slc12a5	solute carrier family 12 (potassium-chloride transporter), member 5	0.011
Apln	apelin	0.011
Acr	acrosin	0.010
Psd	pleckstrin and Sec7 domain containing	0.010
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.010
Apod	apolipoprotein D	0.010
Cxcr4	chemokine (C-X-C motif) receptor 4	0.010
RGD1305627	hypothetical LOC314467	0.010
Faim2	Fas apoptotic inhibitory molecule 2	0.010
Tomm40b	translocase of outer mitochondrial membrane 40 homolog B (yeast)	0.010
Dlg3	discs, large homolog 3 (Drosophila)	0.010
Kcnq2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.010	Mouse
Lim2	lens intrinsic membrane protein 2	0.010
Aqp2	aquaporin 2 (collecting duct)	0.010
Olr1500	olfactory receptor 1500	0.010
Syt8	synaptotagmin VIII	0.010
Scnn1g	sodium channel, nonvoltage-gated 1, gamma	0.010
Chrnb4	cholinergic receptor, nicotinic, beta 4	0.010
Prkg2	protein kinase, cGMP-dependent, type II	0.010
Ryr2	ryanodine receptor 2, cardiac	0.010
Mmp9	matrix metallopeptidase 9	0.010