IMP

Process View

Rattus norvegicus

19 genes annotated in rat

cellular response to dna damage stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to dna damage stimulus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular response to dna damage stimulus" (in gray)

Name	Description	Probability	Func Analog Organism
Psmc1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.231	Fly
Psmb3	proteasome (prosome, macropain) subunit, beta type 3	0.119	Fly
Psmc2	proteasome (prosome, macropain) 26S subunit, ATPase 2	0.099	Fly
Ptbp1	polypyrimidine tract binding protein 1	0.086	Fly
Psme2	proteasome (prosome, macropain) activator subunit 2	0.080
Psmb2	proteasome (prosome, macropain) subunit, beta type 2	0.064	Fly
Dnaja2	DnaJ (Hsp40) homolog, subfamily A, member 2	0.055	Rat
Cdk4	cyclin-dependent kinase 4	0.045
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.040	Fly
Psma4	proteasome (prosome, macropain) subunit, alpha type 4	0.036
Psmc5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.033	Yeast Fly
Rfc4	replication factor C (activator 1) 4	0.032
Psmd13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.031
Timeless	timeless homolog (Drosophila)	0.029
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.027
Oaz1	ornithine decarboxylase antizyme 1	0.027
Stip1	stress-induced phosphoprotein 1	0.027
Mapk1	mitogen activated protein kinase 1	0.026	Mouse Fly
Kifc1	kinesin family member C1	0.026
Taok1	TAO kinase 1	0.025	Human
Cdk2	cyclin dependent kinase 2	0.025	Yeast
Icam1	intercellular adhesion molecule 1	0.025
Arf6	ADP-ribosylation factor 6	0.025
Top2a	topoisomerase (DNA) II alpha	0.024
Tmpo	thymopoietin	0.024
Atf2	activating transcription factor 2	0.023	Human
Psmd7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.023
Psmb7	proteasome (prosome, macropain) subunit, beta type 7	0.022	Fly
Psmc3	proteasome (prosome, macropain) 26S subunit, ATPase 3	0.022
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.022
Eif4a2	eukaryotic translation initiation factor 4A, isoform 2	0.021	Fly
Ptges3	prostaglandin E synthase 3 (cytosolic)	0.020
Rrm2	ribonucleotide reductase M2	0.020
Irf1	interferon regulatory factor 1	0.020
Ube2c	ubiquitin-conjugating enzyme E2C	0.019
Rpa2	replication protein A2	0.018
Nsfl1c	NSFL1 (p97) cofactor (p47)	0.018
Creb1	cAMP responsive element binding protein 1	0.018
Arnt	aryl hydrocarbon receptor nuclear translocator	0.017
Psmc4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.017	Fly
Cherp	calcium homeostasis endoplasmic reticulum protein	0.017
Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isoform	0.016
Sf1	splicing factor 1	0.016
Mdm2	Mdm2 p53 binding protein homolog (mouse)	0.016
Cxcl16	chemokine (C-X-C motif) ligand 16	0.016
Foxm1	forkhead box M1	0.016	Human
Cand1	cullin-associated and neddylation-dissociated 1	0.015
Tyms	thymidylate synthetase	0.015
Usp47	ubiquitin specific peptidase 47	0.015	Human Mouse
Ppp2ca	protein phosphatase 2, catalytic subunit, alpha isoform	0.015
Spc25	SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.015
Lmnb1	lamin B1	0.015
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.015	Mouse
Psmb4	proteasome (prosome, macropain) subunit, beta type 4	0.014
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.014
Psma5	proteasome (prosome, macropain) subunit, alpha type 5	0.014
Psma7	proteasome (prosome, macropain) subunit, alpha type 7	0.014	Fly
Actb	actin, beta	0.014	Yeast
Pfn1	profilin 1	0.014
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.014	Fly
Zfp36	zinc finger protein 36	0.014
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.014
Ifi30	interferon gamma inducible protein 30	0.014
Top2b	topoisomerase (DNA) II beta	0.014
Psmd6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.013
Vcp	valosin-containing protein	0.013	Human
Ifitm3	interferon induced transmembrane protein 3	0.013
Myo1b	myosin Ib	0.013
Psmd1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.013
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.013	Fly
Txnrd1	thioredoxin reductase 1	0.013
Zc3h15	zinc finger CCCH-type containing 15	0.013
Psmd4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.013
Psmd12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.013
Lbr	lamin B receptor	0.013
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.013
Tp53	tumor protein p53	0.013	Human
Timp1	TIMP metallopeptidase inhibitor 1	0.013
Errfi1	ERBB receptor feedback inhibitor 1	0.012
Usp9x	ubiquitin specific peptidase 9, X-linked	0.012
Mcm6	minichromosome maintenance complex component 6	0.012
Racgap1	Rac GTPase-activating protein 1	0.012
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform	0.012
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.012
Tmsb4x	thymosin beta 4, X-linked	0.012
Sumo1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.012
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.012
Ube2g1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.011
Zfand6	zinc finger, AN1-type domain 6	0.011
Socs3	suppressor of cytokine signaling 3	0.011
Ssrp1	structure specific recognition protein 1	0.011
Apex1	APEX nuclease (multifunctional DNA repair enzyme) 1	0.011
Ireb2	iron responsive element binding protein 2	0.011
Mark2	MAP/microtubule affinity-regulating kinase 2	0.011
Actg1	actin, gamma 1	0.011	Yeast
Cops6	COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)	0.010	Fly
Ubc	ubiquitin C	0.010
Actr10	actin-related protein 10 homolog (S. cerevisiae)	0.010
Exoc5	exocyst complex component 5	0.010
Raf1	v-raf-leukemia viral oncogene 1	0.010
Rgs19	regulator of G-protein signaling 19	0.010
Kif2c	kinesin family member 2C	0.010
Irs3	insulin receptor substrate 3	0.010
LOC100364212	heterogeneous nuclear ribonucleoprotein K-like	0.010