IMP

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Rattus norvegicus

1 genes annotated in rat

Multi-species View

positive regulation of serotonin secretion

GO:0014064

Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of serotonin secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of serotonin secretion" (in gray)

Name	Description	Probability	Func Analog Organism
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.293
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.271
Atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.266
Olr1867	olfactory receptor 1867	0.187
Gck	glucokinase	0.185
Oprk1	opioid receptor, kappa 1	0.151
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.133
Nfasc	neurofascin	0.116
Cyp4a8	cytochrome P450, family 4, subfamily a, polypeptide 8	0.114
G6pc	glucose-6-phosphatase, catalytic subunit	0.114
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.112
N5	DNA binding protein N5	0.098
Colq	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	0.096
Slc22a25	solute carrier family 22, member 25	0.094
Slc8a3	solute carrier family 8 (sodium/calcium exchanger), member 3	0.087
Dcc	deleted in colorectal carcinoma	0.086
Htr5a	5-hydroxytryptamine (serotonin) receptor 5A	0.086
Acrv1	acrosomal vesicle protein 1	0.084
Olr1078	olfactory receptor 1078	0.084
Il9r	interleukin 9 receptor	0.083
Avp	arginine vasopressin	0.079
Notch3	Notch homolog 3 (Drosophila)	0.079
Chrna7	cholinergic receptor, nicotinic, alpha 7	0.074
Vipr2	vasoactive intestinal peptide receptor 2	0.067	Rat
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.064
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.064
Uncx	UNC homeobox	0.063
St18	suppression of tumorigenicity 18	0.062
Grm8	glutamate receptor, metabotropic 8	0.062
Gzmk	granzyme K	0.060
Hcrt	hypocretin	0.060
Accn2	amiloride-sensitive cation channel 2, neuronal	0.060
Hrh3	histamine receptor H3	0.055
Mrgprf	MAS-related GPR, member F	0.053
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1	0.053
Grin2c	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.050
Ager	advanced glycosylation end product-specific receptor	0.049
Atp2a3	ATPase, Ca++ transporting, ubiquitous	0.049
Syt7	synaptotagmin VII	0.047
Kcnh6	potassium voltage-gated channel, subfamily H (eag-related), member 6	0.047
Slc6a11	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	0.046
Hand1	heart and neural crest derivatives expressed 1	0.045
Fev	FEV (ETS oncogene family)	0.044
Olr1641	olfactory receptor 1641	0.044
Th	tyrosine hydroxylase	0.043
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.043
Tnfrsf8	tumor necrosis factor receptor superfamily, member 8	0.043
RGD1306474	similar to RIKEN cDNA 9530003J23	0.041
Pla2g2c	phospholipase A2, group IIC	0.040
Prm3	protamine 3	0.040
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.040
Ncan	neurocan	0.040
Slc5a2	solute carrier family 5 (sodium/glucose cotransporter), member 2	0.040
Chrm2	cholinergic receptor, muscarinic 2	0.040
Slco2b1	solute carrier organic anion transporter family, member 2b1	0.039
Meis3	Meis homeobox 3	0.039
Calcr	calcitonin receptor	0.038	Rat
Bcl2l10	BCL2-like 10 (apoptosis facilitator)	0.038
Ctsj	cathepsin J	0.037
Dspp	dentin sialophosphoprotein	0.037
Avpr1b	arginine vasopressin receptor 1B	0.036
Cx3cr1	chemokine (C-X3-C motif) receptor 1	0.036
Adora2a	adenosine A2a receptor	0.036
Adam1a	a disintegrin and metallopeptidase domain 1a	0.036
Nkx6-1	NK6 homeobox 1	0.036
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.035
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.035
Zic1	Zic family member 1 (odd-paired homolog, Drosophila)	0.034
Teddm1	transmembrane epididymal protein 1	0.034
Cyp27b1	cytochrome P450, family 27, subfamily b, polypeptide 1	0.034
Gja6	gap junction protein, alpha 6	0.034
Cntfr	ciliary neurotrophic factor receptor	0.034
Hrh2	histamine receptor H 2	0.033
Ar	androgen receptor	0.033
Prkg2	protein kinase, cGMP-dependent, type II	0.032
Faslg	Fas ligand (TNF superfamily, member 6)	0.032
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.032
Ppyr1	pancreatic polypeptide receptor 1	0.032
LOC56764	dnaj-like protein	0.032
Oprl1	opiate receptor-like 1	0.032
Csrnp2	cysteine-serine-rich nuclear protein 2	0.032
Grm6	glutamate receptor, metabotropic 6	0.031
Scn10a	sodium channel, voltage-gated, type X, alpha subunit	0.031
Rhd	Rh blood group, D antigen	0.031
Tgfbr3	transforming growth factor, beta receptor III	0.031
Olr59	olfactory receptor 59	0.031
Olr1496	olfactory receptor 1496	0.031
Mylk2	myosin light chain kinase 2	0.030
Agxt2	alanine-glyoxylate aminotransferase 2	0.030
Olr414	olfactory receptor 414	0.029
Hcn3	hyperpolarization-activated cyclic nucleotide-gated potassium channel 3	0.029
Nmbr	neuromedin B receptor	0.028
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.028
Cd28	Cd28 molecule	0.027
Gucy1b2	guanylate cyclase 1, soluble, beta 2	0.027
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.027
RGD1308759	similar to KIAA0892 protein	0.027
Psp	parotid secretory protein	0.027
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, gamma 1	0.026
Chrna2	cholinergic receptor, nicotinic, alpha 2 (neuronal)	0.026
Pon1	paraoxonase 1	0.026
P2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.026
Gng7	guanine nucleotide binding protein (G protein), gamma 7	0.026
Csn2	casein beta	0.026
Pmch	pro-melanin-concentrating hormone	0.025
Znf483	zinc finger protein 483	0.025
Cartpt	CART prepropeptide	0.025
Lep	leptin	0.025
Kif6	kinesin family member 6	0.025
Aqp2	aquaporin 2 (collecting duct)	0.025
Fxyd4	FXYD domain-containing ion transport regulator 4	0.025
Crhr2	corticotropin releasing hormone receptor 2	0.024
Gabra3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	0.024
Mag	myelin-associated glycoprotein	0.024
Kcna5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.024
Gad2	glutamate decarboxylase 2	0.023
Bcl2	B-cell CLL/lymphoma 2	0.023
Pnoc	prepronociceptin	0.023
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.023
Wfdc6a	WAP four-disulfide core domain 6A	0.023
Adam3a	ADAM metallopeptidase domain 3A (cyritestin 1)	0.023
Kcnh3	potassium voltage-gated channel, subfamily H (eag-related), member 3	0.023
Bcan	brevican	0.023
Afm	afamin	0.023
St8sia3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	0.022
Epor	erythropoietin receptor	0.022
Kcnq3	potassium voltage-gated channel, KQT-like subfamily, member 3	0.022
Gpr1	G protein-coupled receptor 1	0.022
Slc16a8	solute carrier family 16, member 8 (monocarboxylic acid transporter 3)	0.022
Hhip	Hedgehog-interacting protein	0.021
Abcc6	ATP-binding cassette, subfamily C (CFTR/MRP), member 6	0.021
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.021
Iapp	islet amyloid polypeptide	0.021
Rasgrf1	RAS protein-specific guanine nucleotide-releasing factor 1	0.021
Gucy2d	guanylate cyclase 2d	0.021
Gabrg3	gamma-aminobutyric acid (GABA) A receptor, gamma 3	0.020
Olr1654	olfactory receptor 1654	0.020
Slc6a7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7	0.020
Slc22a6	solute carrier family 22 (organic anion transporter), member 6	0.020
Tmem79	transmembrane protein 79	0.020
Rgs9	regulator of G-protein signaling 9	0.020
Pde1b	phosphodiesterase 1B, calmodulin-dependent	0.020
Syt3	synaptotagmin III	0.020
Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	0.020
Folh1	folate hydrolase 1	0.019
Foxa1	forkhead box A1	0.019
Vwa3a	von Willebrand factor A domain containing 3A	0.019
Barhl1	BarH-like homeobox 1	0.019
Slc18a3	solute carrier family 18 (vesicular acetylcholine), member 3	0.019
Rup2	urinary protein 2	0.019
Ucn	urocortin	0.019
Cd40lg	CD40 ligand	0.019
Chrna4	cholinergic receptor, nicotinic, alpha 4	0.019
Gjd2	gap junction protein, delta 2	0.019
Akr1c18	aldo-keto reductase family 1, member C18	0.019
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.019
Kynu	kynureninase (L-kynurenine hydrolase)	0.019
Phkg1	phosphorylase kinase, gamma 1	0.019
Mpp2	membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)	0.018
Cyss	cystatin S	0.018
Hoxa4	homeo box A4	0.018
Prl6a1	prolactin family 6, subfamily a, member 1	0.018
Gfra2	GDNF family receptor alpha 2	0.018
Csf1	colony stimulating factor 1 (macrophage)	0.018
Cacna1e	calcium channel, voltage-dependent, R type, alpha 1E subunit	0.018
Cnga4	cyclic nucleotide gated channel alpha 4	0.018
Lhb	luteinizing hormone beta	0.018
Htr3a	5-hydroxytryptamine (serotonin) receptor 3a	0.017
Snhg11	small nucleolar RNA host gene 11	0.017
LOC293989	cytochrome P450-like	0.017
P2rx3	purinergic receptor P2X, ligand-gated ion channel, 3	0.017
LOC304903	similar to Pappalysin-2 precursor (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP-E)	0.017
Mep1a	meprin 1 alpha	0.017
Slc14a1	solute carrier family 14 (urea transporter), member 1	0.017
Cacng5	calcium channel, voltage-dependent, gamma subunit 5	0.017
Haao	3-hydroxyanthranilate 3,4-dioxygenase	0.017
Grk1	G protein-coupled receptor kinase 1	0.017
RGD1310262	hypothetical LOC304650	0.017
Mapk4	mitogen-activated protein kinase 4	0.017
Slc30a2	solute carrier family 30 (zinc transporter), member 2	0.017
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.017
Afap1	actin filament associated protein 1	0.017
Npffr2	neuropeptide FF receptor 2	0.016
Lepr	leptin receptor	0.016
Vom2r53	vomeronasal 2 receptor, 53	0.016
Nf1	neurofibromin 1	0.016
Trhr2	thyrotropin releasing hormone receptor 2	0.016
Abcc8	ATP-binding cassette, subfamily C (CFTR/MRP), member 8	0.016
Ncr1	natural cytotoxicity triggering receptor 1	0.016
Sftpc	surfactant protein C	0.016
Fam38b	family with sequence similarity 38, member B	0.016
Ptch1	patched homolog 1 (Drosophila)	0.016
Olr416	olfactory receptor 416	0.016
Kcnh8	potassium voltage-gated channel, subfamily H (eag-related), member 8	0.016
Ifna1	interferon-alpha 1	0.016
Tnfsf4	tumor necrosis factor (ligand) superfamily, member 4	0.016
Cntn6	contactin 6	0.016
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.015
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.015
Samd12	sterile alpha motif domain containing 12	0.015
Smgb	neonatal submandibular gland protein B	0.015
Notch4	Notch homolog 4 (Drosophila)	0.015
Gabrd	gamma-aminobutyric acid (GABA) A receptor, delta	0.015
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.015
Krt31	keratin 31	0.015
Grik3	glutamate receptor, ionotropic, kainate 3	0.015
Cbln1	cerebellin 1 precursor	0.015
Adra2c	adrenergic, alpha-2C-, receptor	0.015
Syt9	synaptotagmin IX	0.015
Psg29	pregnancy-specific glycoprotein 29	0.015
Olr226	olfactory receptor 226	0.015
Umod	uromodulin	0.015
Mcpt3	mast cell peptidase 3	0.015
Akr1d1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.015
Pcyt1b	phosphate cytidylyltransferase 1, choline, beta	0.015
Dll3	delta-like 3 (Drosophila)	0.015
Gjb4	gap junction protein, beta 4	0.015
Cnga1	cyclic nucleotide gated channel alpha 1	0.014
Olr1271	olfactory receptor 1271	0.014
Gapdhs	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.014
Hbz	hemoglobin, zeta	0.014
Gabrr3	gamma-aminobutyric acid (GABA) receptor, rho 3	0.014
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.014
Pdyn	prodynorphin	0.014
Isl1	ISL LIM homeobox 1	0.014
Shc3	SHC (Src homology 2 domain containing) transforming protein 3	0.014
Hbg1	hemoglobin, gamma A	0.014
Prlhr	prolactin releasing hormone receptor	0.014
Pip4k2b	phosphatidylinositol-5-phosphate 4-kinase, type II, beta	0.014
Prl2a1	Prolactin family 2, subfamily a, member 1	0.014
Tnp2	transition protein 2	0.014
Lnpep	leucyl/cystinyl aminopeptidase	0.014
Hcn4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	0.014
Arhgap23	Rho GTPase activating protein 23	0.014
Grp	gastrin releasing peptide	0.014
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.014
Prss21	protease, serine, 21	0.014
RGD1565493	similar to DKFZP434I092 protein	0.014
Lims1	LIM and senescent cell antigen-like domains 1	0.014
Prl3d4	prolactin family 3, subfamily d, member 4	0.014
Grm1	glutamate receptor, metabotropic 1	0.014
Tbx2	T-box 2	0.014
Rhobtb2	Rho-related BTB domain containing 2	0.014
Nr2c2	nuclear receptor subfamily 2, group C, member 2	0.014
Hoxa1	homeo box A1	0.014
Tacr1	tachykinin receptor 1	0.014
Grpr	gastrin releasing peptide receptor	0.013
Glra1	glycine receptor, alpha 1	0.013
Nrl	neural retina leucine zipper	0.013
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.013
Gpr6	G protein-coupled receptor 6	0.013
Cnga2	cyclic nucleotide gated channel alpha 2	0.013
Sycp3	synaptonemal complex protein 3	0.013
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.013
Tbxa2r	thromboxane A2 receptor	0.013
Inhbe	inhibin beta E	0.013
RGD1559748	similar to Palate lung and nasal carcinoma-like protein precursor (Tongue plunc-like protein)	0.013
Dlk1	delta-like 1 homolog (Drosophila)	0.013
Ghrl	ghrelin/obestatin prepropeptide	0.013
Olr1493	olfactory receptor gene Olr1493	0.013
Gsg1l	GSG1-like	0.013
RGD1560608	similar to novel protein	0.013
Apoa4	apolipoprotein A-IV	0.013
Slc6a18	solute carrier family 6, member 18	0.013
Slc7a3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	0.013
Smr3a	submaxillary gland androgen regulated protein 3A	0.013
Cntn3	contactin 3 (plasmacytoma associated)	0.013
Vwa5b2	von Willebrand factor A domain containing 5B2	0.013
Slc2a5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	0.013
Hbe1	hemoglobin, epsilon 1	0.013
Gabrq	gamma-aminobutyric acid (GABA) receptor, theta	0.013
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.013
Robo1	roundabout homolog 1 (Drosophila)	0.013
Pde1c	phosphodiesterase 1C	0.013
Accn3	amiloride-sensitive cation channel 3	0.013
Gpha2	glycoprotein hormone alpha 2	0.013
Insrr	insulin receptor-related receptor	0.013
Slc22a13	solute carrier family 22 (organic anion transporter), member 13	0.012
St6galnac3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	0.012
Svs4	seminal vesicle secretory protein 4	0.012
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.012
Mc5r	melanocortin 5 receptor	0.012
Gabra6	gamma-aminobutyric acid (GABA) A receptor, alpha 6	0.012
Lbxcor1	LBXCOR1 homolog (mouse)	0.012
Chrng	cholinergic receptor, nicotinic, gamma	0.012
LOC360479	similar to hypothetical protein	0.012
Agtr2	angiotensin II receptor, type 2	0.012
Hsd17b1	hydroxysteroid (17-beta) dehydrogenase 1	0.012
Cxcr3	chemokine (C-X-C motif) receptor 3	0.012
Tnni3	troponin I type 3 (cardiac)	0.012
Hadh	hydroxyacyl-Coenzyme A dehydrogenase	0.012
Aqp6	aquaporin 6, kidney specific	0.012
Ptprz1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.012
Kcnt1	potassium channel, subfamily T, member 1	0.012
Plin	perilipin	0.012
Utrn	utrophin	0.012
Pfkfb3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	0.012
Itga2b	integrin, alpha 2B	0.012
Hrk	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.012
Glp1r	glucagon-like peptide 1 receptor	0.012	Rat
Adora3	adenosine A3 receptor	0.012
Spata2L	spermatogenesis associated 2-like	0.012
Chm	choroideremia (Rab escort protein 1)	0.011
Clock	clock homolog (mouse)	0.011
Cacng4	calcium channel, voltage-dependent, gamma subunit 4	0.011
Chrnb3	cholinergic receptor, nicotinic, beta 3	0.011
Myl7	myosin, light chain 7, regulatory	0.011
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.011
Mospd4	motile sperm domain containing 4	0.011
Hcrtr1	hypocretin (orexin) receptor 1	0.011
Gipr	gastric inhibitory polypeptide receptor	0.011	Rat
Adra1a	adrenergic, alpha-1A-, receptor	0.011
LOC286987	hemiferrin, transferrin-like protein	0.011
Syt11	synaptotagmin XI	0.011
LOC100362634	myeloid/lymphoid or mixed-lineage leukemia 2	0.011
Sstr3	somatostatin receptor 3	0.011
Fam148b	family with sequence similarity 148, member B	0.011
Kcnn3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	0.011
Oxtr	oxytocin receptor	0.011
Drd2	dopamine receptor D2	0.011
Pcsk9	proprotein convertase subtilisin/kexin type 9	0.011
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.011
Gab2	GRB2-associated binding protein 2	0.011
Hpca	hippocalcin	0.011
Olr37	olfactory receptor 37	0.011
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.011
Spata9	spermatogenesis associated 9	0.011
Unc13c	unc-13 homolog C (C. elegans)	0.011
Scn4a	sodium channel, voltage-gated, type IV, alpha subunit	0.011
Padi3	peptidyl arginine deiminase, type III	0.011
Grm2	glutamate receptor, metabotropic 2	0.011
Mare	alpha globin regulatory element containing gene	0.011
Celsr3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)	0.011
Kiss1r	KISS1 receptor	0.011
Ccbp2	chemokine binding protein 2	0.011
Ins2	insulin 2	0.010
Grm4	glutamate receptor, metabotropic 4	0.010
Azgp1	alpha-2-glycoprotein 1, zinc-binding	0.010
Ceacam3	carcinoembryonic antigen-related cell adhesion molecule 3	0.010
Pklr	pyruvate kinase, liver and RBC	0.010
Cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.010
Bhlha15	basic helix-loop-helix family, member a15	0.010
Grin2b	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.010
Hcrtr2	hypocretin (orexin) receptor 2	0.010
Ntsr1	neurotensin receptor 1	0.010
Olr1082	olfactory receptor 1082	0.010
Ptgfr	prostaglandin F receptor	0.010