IMP

Process View

Rattus norvegicus

16 genes annotated in rat

regulation of protein catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of protein catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of protein catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Dnaja2	DnaJ (Hsp40) homolog, subfamily A, member 2	0.414
Ube2g1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.324
Phkg1	phosphorylase kinase, gamma 1	0.128
Eef2	eukaryotic translation elongation factor 2	0.125
Gja1	gap junction protein, alpha 1	0.118
Magi2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.114
Hprt1	hypoxanthine phosphoribosyltransferase 1	0.083
Nudt3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.072
Mapre1	microtubule-associated protein, RP/EB family, member 1	0.067
Cd14	CD14 molecule	0.060
Ccnb1	cyclin B1	0.052
Cnbp	CCHC-type zinc finger, nucleic acid binding protein	0.044
Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	0.035
Eif4a2	eukaryotic translation initiation factor 4A, isoform 2	0.035
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.032
Ppp2ca	protein phosphatase 2, catalytic subunit, alpha isoform	0.030
Vapa	VAMP (vesicle-associated membrane protein)-associated protein A	0.030
Psmc5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.029
Vcp	valosin-containing protein	0.029
Sstr3	somatostatin receptor 3	0.026
Psmd2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.026
Rap1b	RAP1B, member of RAS oncogene family	0.025
Prkca	protein kinase C, alpha	0.025
LOC100310874	antisense RNA overlapping MCH	0.025
Cops2	COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)	0.025
Psmc1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.024
Psmd7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.023
Nploc4	nuclear protein localization 4 homolog (S. cerevisiae)	0.023
Dlg4	discs, large homolog 4 (Drosophila)	0.021
Grasp	GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein	0.021
Sumo1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.021	Human
Smad7	SMAD family member 7	0.021
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.021
Usf2	upstream transcription factor 2, c-fos interacting	0.021
Ptges3	prostaglandin E synthase 3 (cytosolic)	0.020
Ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.020
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.020
Usp47	ubiquitin specific peptidase 47	0.020
Cdh22	cadherin 22	0.019
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.019
Rpn2	ribophorin II	0.018
Shank3	SH3 and multiple ankyrin repeat domains 3	0.018
Gfi1	growth factor independent 1 transcription repressor	0.018
Pfkfb3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	0.018
Psmc2	proteasome (prosome, macropain) 26S subunit, ATPase 2	0.018	Yeast
Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.017
Psmc3	proteasome (prosome, macropain) 26S subunit, ATPase 3	0.017
Plk1	polo-like kinase 1 (Drosophila)	0.017	Human Rat
Ipo5	importin 5	0.016
Cx3cl1	chemokine (C-X3-C motif) ligand 1	0.016
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.016
Taok1	TAO kinase 1	0.016
Nsfl1c	NSFL1 (p97) cofactor (p47)	0.016
Tpm4	tropomyosin 4	0.016
Rasgrp1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	0.016
Ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.016
Sgta	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	0.015
Fdxr	ferredoxin reductase	0.015
Prp15	proline-rich protein 15	0.015
Jak1	Janus kinase 1	0.015
Pgr	progesterone receptor	0.015
Pink1	PTEN induced putative kinase 1	0.015
Rpl28	ribosomal protein L28	0.015
Dpp9	dipeptidyl peptidase 9	0.015
March8	membrane-associated ring finger (C3HC4) 8	0.015
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform	0.015
Pde3a	phosphodiesterase 3A, cGMP inhibited	0.015
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.015
Snap29	synaptosomal-associated protein 29	0.014
Il1a	interleukin 1 alpha	0.014
App	amyloid beta (A4) precursor protein	0.014
Hoxb7	homeo box B7	0.014
St3gal3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	0.014
Il1r2	interleukin 1 receptor, type II	0.014
Ppp1r2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.014
Pdcd10	programmed cell death 10	0.014
Cxcl6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.014
Psmd3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.014
Rbbp7	retinoblastoma binding protein 7	0.014
Tomm20	translocase of outer mitochondrial membrane 20 homolog (yeast)	0.013
Cenpn	centromere protein N	0.013
Top2a	topoisomerase (DNA) II alpha	0.013
Adrbk1	adrenergic, beta, receptor kinase 1	0.013
Myo1b	myosin Ib	0.013
Il6	interleukin 6	0.013
Snx6	sorting nexin 6	0.013	Rat
Prc1	protein regulator of cytokinesis 1	0.013
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.012	Rat
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.012
Vcan	versican	0.012
Zfp37	zinc finger protein 37	0.012
Ccl2	chemokine (C-C motif) ligand 2	0.012
Anxa1	annexin A1	0.012
Birc5	baculoviral IAP repeat-containing 5	0.012
S100a8	S100 calcium binding protein A8	0.012
Rbm8a	RNA binding motif protein 8A	0.012
Epb4.1l2	erythrocyte membrane protein band 4.1-like 2	0.012
Ccr1	chemokine (C-C motif) receptor 1	0.012
Gja5	gap junction protein, alpha 5	0.012	Rat
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.012
Usp19	ubiquitin specific peptidase 19	0.012
Stx12	syntaxin 12	0.012
Grm5	glutamate receptor, metabotropic 5	0.011
Rab10	RAB10, member RAS oncogene family	0.011
Cct4	chaperonin containing Tcp1, subunit 4 (delta)	0.011
Ubl3	ubiquitin-like 3	0.011
Nrxn1	neurexin 1	0.011
Slc28a1	solute carrier family 28 (sodium-coupled nucleoside transporter), member 1	0.011
Kif18b	kinesin family member 18B	0.011
Paip2	poly(A) binding protein interacting protein 2	0.011
Epha2	Eph receptor A2	0.011
Cxcl2	chemokine (C-X-C motif) ligand 2	0.011
S100a11	S100 calcium binding protein A11 (calizzarin)	0.011
Mprip	myosin phosphatase Rho interacting protein	0.011
Ndrg2	N-myc downstream regulated gene 2	0.011
Il1b	interleukin 1 beta	0.011	Human
Ptprs	protein tyrosine phosphatase, receptor type, S	0.011
Ripk3	receptor-interacting serine-threonine kinase 3	0.011
Dlgap4	discs, large homolog-associated protein 4 (Drosophila)	0.011	Rat
Cdca2	cell division cycle associated 2	0.011
Psmd6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.011
Atf3	activating transcription factor 3	0.011
Ctnnb1	catenin (cadherin associated protein), beta 1	0.011
Ctss	cathepsin S	0.011
Dnajb5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.011
Inpp5j	inositol polyphosphate-5-phosphatase J	0.010
Picalm	phosphatidylinositol binding clathrin assembly protein	0.010
Hmmr	hyaluronan mediated motility receptor (RHAMM)	0.010
Spag5	sperm associated antigen 5	0.010
Stag1	stromal antigen 1	0.010
Bcl2l2	Bcl2-like 2	0.010
Myo1c	myosin IC	0.010
Serpine2	serine (or cysteine) peptidase inhibitor, clade E, member 2	0.010
Lgals3	lectin, galactoside-binding, soluble, 3	0.010