IMP

Process View

Rattus norvegicus

34 genes annotated in rat

Multi-species View

regulation of lymphocyte activation

GO:0051249

Any process that modulates the frequency, rate or extent of lymphocyte activation.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of lymphocyte activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of lymphocyte activation" (in gray)

Name	Description	Probability	Func Analog Organism
Cd247	Cd247 molecule	0.246
Cd2	Cd2 molecule	0.151
Cd37	CD37 molecule	0.111
Ptprc	protein tyrosine phosphatase, receptor type, C	0.066	Human Mouse
RT1-Da	RT1 class II, locus Da	0.063
Cd4	Cd4 molecule	0.058	Human Mouse
Cd5	Cd5 molecule	0.055
Ciita	class II, major histocompatibility complex, transactivator	0.051
Laptm5	lysosomal protein transmembrane 5	0.048
Ctss	cathepsin S	0.048
Gzmk	granzyme K	0.042
Spn	sialophorin	0.041
Casp1	caspase 1	0.039
Grin2a	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.034
Ccr5	chemokine (C-C motif) receptor 5	0.034
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.031	Mouse
Fcgr2a	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.029	Mouse
Cxcr3	chemokine (C-X-C motif) receptor 3	0.029
Il1r1	interleukin 1 receptor, type I	0.028
Mmp10	matrix metallopeptidase 10	0.028
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.027	Rat
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.027
Il9r	interleukin 9 receptor	0.026
Il2rb	interleukin 2 receptor, beta	0.026
Pik3cd	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.025
Inpp5d	inositol polyphosphate-5-phosphatase D	0.025	Mouse
Hck	hemopoietic cell kinase	0.024
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.024
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.023
Tas2r123	taste receptor, type 2, member 123	0.023
Itgad	integrin, alpha D	0.023
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.022
RT1-DMb	RT1 class II, locus DMb	0.022
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.022
Lat	linker for activation of T cells	0.022
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.022
Il6st	interleukin 6 signal transducer	0.021	Human
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.021
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.021
LOC100364854	similar to RIKEN cDNA A430107P09 gene-like	0.021
Mcpt2	mast cell protease 2	0.021
RT1-DMa	RT1 class II, locus DMa	0.020
Map4k1	mitogen activated protein kinase kinase kinase kinase 1	0.020
Itgb7	integrin, beta 7	0.020
Vip	vasoactive intestinal peptide	0.020
Anpep	alanyl (membrane) aminopeptidase	0.020
Cd44	Cd44 molecule	0.019
Prrx1	paired related homeobox 1	0.019
Scn11a	sodium channel, voltage-gated, type XI, alpha	0.019
Alox5	arachidonate 5-lipoxygenase	0.019
Lcp2	lymphocyte cytosolic protein 2	0.018
Calcr	calcitonin receptor	0.018
Tcrb	T-cell receptor beta chain	0.018
Slfn2	schlafen 2	0.017
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.017	Rat
Nkg7	natural killer cell group 7 sequence	0.017
C1qb	complement component 1, q subcomponent, B chain	0.017
Flt1	FMS-related tyrosine kinase 1	0.017	Rat
Anxa2	annexin A2	0.017
Socs3	suppressor of cytokine signaling 3	0.017
Ccr2	chemokine (C-C motif) receptor 2	0.016	Mouse
Gja4	gap junction protein, alpha 4	0.016
Lef1	lymphoid enhancer binding factor 1	0.016
Cd3g	CD3 molecule, gamma	0.016
Csf1	colony stimulating factor 1 (macrophage)	0.016
Kcns1	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1	0.016
Pth	parathyroid hormone	0.016
Cacng1	calcium channel, voltage-dependent, gamma subunit 1	0.015
Icam1	intercellular adhesion molecule 1	0.015
Kcnv1	potassium channel, subfamily V, member 1	0.015
Reg3g	regenerating islet-derived 3 gamma	0.015
Cd53	Cd53 molecule	0.015
Rac1	ras-related C3 botulinum toxin substrate 1	0.015
Mylk2	myosin light chain kinase 2	0.015
Svs1	seminal vesicle secretory protein 1	0.015
Podxl	podocalyxin-like	0.015
Cd86	CD86 molecule	0.015
Ralbp1	ralA binding protein 1	0.015
Scp2	sterol carrier protein 2	0.015
Bin2	bridging integrator 2	0.015
Il6	interleukin 6	0.014
Serpinb1a	serine (or cysteine) proteinase inhibitor, clade B, member 1a	0.014
Stat6	signal transducer and activator of transcription 6	0.014	Mouse
Cfp	complement factor properdin	0.014
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.014
Ccl4	chemokine (C-C motif) ligand 4	0.014
Il1b	interleukin 1 beta	0.014
Ddr2	discoidin domain receptor tyrosine kinase 2	0.014
Cxcl3	chemokine (C-X-C motif) ligand 3	0.014
LOC100361706	lambda-chain C1-region-like	0.014
Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.014
Fgfr2	fibroblast growth factor receptor 2	0.014
Kl	Klotho	0.014
Arhgap25	Rho GTPase activating protein 25	0.014
Plcg2	phospholipase C, gamma 2	0.013
Tgfbr3	transforming growth factor, beta receptor III	0.013
Psbpc2	prostatic steroid-binding protein C2	0.013
Wipf1	WAS/WASL interacting protein family, member 1	0.013
Cd200r1	CD200 receptor 1	0.013
Sell	selectin L	0.013
Casp3	caspase 3	0.013
LOC100361571	keratin associated protein 1-3-like	0.013
Olr1500	olfactory receptor 1500	0.013
Cyp11b3	cytochrome P450, family 11, subfamily b, polypeptide 3	0.013
Cd14	CD14 molecule	0.013
Syt8	synaptotagmin VIII	0.013
Slco2b1	solute carrier organic anion transporter family, member 2b1	0.013
Plin	perilipin	0.013
Si	sucrase-isomaltase (alpha-glucosidase)	0.013
Prol1	proline rich, lacrimal 1	0.013
Teddm1	transmembrane epididymal protein 1	0.013
Adfp	adipose differentiation related protein	0.013
Hdac7	histone deacetylase 7	0.013
Tgfbr2	transforming growth factor, beta receptor II	0.013	Mouse
Il18	interleukin 18	0.013
Gucy2d	guanylate cyclase 2d	0.013
Gpr114	G protein-coupled receptor 114	0.013
Ncr1	natural cytotoxicity triggering receptor 1	0.012
Hmha1	histocompatibility (minor) HA-1	0.012
Serpinb7	serpin peptidase inhibitor, clade B (ovalbumin), member 7	0.012
Kif6	kinesin family member 6	0.012
Prl7a4	prolactin family 7, subfamily a, member 4	0.012
Pecam1	platelet/endothelial cell adhesion molecule 1	0.012
Dchs1	dachsous 1 (Drosophila)	0.012
Gkn1	gastrokine 1	0.012
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.012
Prss27	protease, serine 27	0.012
Ptafr	platelet-activating factor receptor	0.012
Cpxm2	carboxypeptidase X (M14 family), member 2	0.012
Rhog	ras homolog gene family, member G (rho G)	0.012
Nab1	Ngfi-A binding protein 1	0.012
Reg3b	regenerating islet-derived 3 beta	0.012
Baiap2	BAI1-associated protein 2	0.012
MGC112715	hypothetical protein LOC690899	0.012
Gfra2	GDNF family receptor alpha 2	0.012
Arrb1	arrestin, beta 1	0.012
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.012
Cdgap	Cdc42 GTPase-activating protein	0.012
Nos3	nitric oxide synthase 3, endothelial cell	0.012
Adam2	ADAM metallopeptidase domain 2	0.012
Acvr1c	activin A receptor, type IC	0.011
Arhgap4	Rho GTPase activating protein 4	0.011
Syk	spleen tyrosine kinase	0.011	Mouse
Stat4	signal transducer and activator of transcription 4	0.011
Tns3	tensin 3	0.011
Gper	G protein-coupled estrogen receptor 1	0.011
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.011
P2ry14	purinergic receptor P2Y, G-protein coupled, 14	0.011
Htr5a	5-hydroxytryptamine (serotonin) receptor 5A	0.011
Gmeb2	glucocorticoid modulatory element binding protein 2	0.011
Blnk	B-cell linker	0.011
LOC689770	similar to osteoclast inhibitory lectin	0.011
Il10	interleukin 10	0.011	Human
Efnb1	ephrin B1	0.011
Orai1	ORAI calcium release-activated calcium modulator 1	0.011
Cybb	cytochrome b-245, beta polypeptide	0.011
Lyz2	lysozyme 2	0.011
Cd38	CD38 molecule	0.011
Aif1	allograft inflammatory factor 1	0.011	Human
Nmi	N-myc (and STAT) interactor	0.011
Hist1h2ba	histone cluster 1, H2ba	0.011
Psp	parotid secretory protein	0.011
Kcnk13	potassium channel, subfamily K, member 13	0.011
Bid	BH3 interacting domain death agonist	0.011
Grm5	glutamate receptor, metabotropic 5	0.011
Clec10a	C-type lectin domain family 10, member A	0.011
Dlx5	distal-less homeobox 5	0.011
Add2	adducin 2 (beta)	0.011
Stx6	syntaxin 6	0.011
Myh1	myosin, heavy polypeptide 1, skeletal muscle, adult	0.011
Slc8a3	solute carrier family 8 (sodium/calcium exchanger), member 3	0.011
Sat1	spermidine/spermine N1-acetyl transferase 1	0.011
Ltbp3	latent transforming growth factor beta binding protein 3	0.011
Neurog3	neurogenin 3	0.011
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.011
Pdpn	podoplanin	0.011
UST4r	integral membrane transport protein UST4r	0.011
Tnf	tumor necrosis factor (TNF superfamily, member 2)	0.011
Pcdhga11	protocadherin gamma subfamily A, 11	0.011
Igh-6	immunoglobulin heavy chain 6	0.011
Tas2r107	taste receptor, type 2, member 107	0.011
Rhoh	ras homolog gene family, member H	0.011
Psx1	placenta specific homeobox 1	0.010
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.010	Rat
Cryge	crystallin, gamma E	0.010
Ccl5	chemokine (C-C motif) ligand 5	0.010	Human
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.010
Il1rl1	interleukin 1 receptor-like 1	0.010
Unc93b1	unc-93 homolog B1 (C. elegans)	0.010
Itga6	integrin, alpha 6	0.010
Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	0.010
Lilrb3l	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3-like	0.010
Rt1.aa	MHC class I RT1.Aa alpha-chain	0.010
Dock8	dedicator of cytokinesis 8	0.010
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.010
Evi2a	ecotropic viral integration site 2A	0.010
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.010
Cntn1	contactin 1	0.010
Il16	interleukin 16	0.010
Dio2	deiodinase, iodothyronine, type II	0.010
Slc9a1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	0.010
Dusp4	dual specificity phosphatase 4	0.010
Prl8a9	prolactin family 8, subfamily a, member 9	0.010
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.010
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.010
Bgn	biglycan	0.010