IMP

Process View

Danio rerio

2 genes annotated in zebrafish

response to superoxide

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in zebrafish Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to superoxide"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to superoxide" (in gray)

Name	Description	Probability	Func Analog Organism
sod1	superoxide dismutase 1, soluble	0.726
nme2b.1	non-metastatic cells 2b.1, protein (NM23B) expressed in	0.250
sod2	superoxide dismutase 2, mitochondrial	0.226	Human Mouse Worm
cyp3c1	cytochrome P450, family 3, subfamily c, polypeptide 1	0.218
smc1al	structural maintenance of chromosomes 1A, like	0.180
gstp1	glutathione S-transferase pi	0.178
park7	parkinson disease (autosomal recessive, early onset) 7	0.133	Human
acadm	acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain	0.131
zgc:112056	zgc:112056	0.120
cbr1l	carbonyl reductase 1-like	0.120
aldh7a1	aldehyde dehydrogenase 7 family, member A1	0.111
zgc:92027	zgc:92027	0.108
xylt1	xylosyltransferase 1	0.086
LOC792474	annexin A4-like	0.083
prdx2	peroxiredoxin 2	0.075	Human Mouse
rpz	rapunzel	0.065
mapk6	mitogen-activated protein kinase 6	0.064
ndufa9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9	0.064
urod	uroporphyrinogen decarboxylase	0.063
mapk3	mitogen-activated protein kinase 3	0.060
zgc:64133	zgc:64133	0.055
mif	macrophage migration inhibitory factor	0.054
uxs1	UDP-glucuronic acid decarboxylase 1	0.046
ndufa8	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8	0.046
ppox	protoporphyrinogen oxidase	0.046
zgc:73293	zgc:73293	0.045
rfng	radical fringe homolog (Drosophila)	0.045
tfr1a	transferrin receptor 1a	0.045
kpna3	karyopherin (importin) alpha 3	0.041
si:ch211-57k11.10	si:ch211-57k11.10	0.039
npepps	aminopeptidase puromycin sensitive	0.038
zgc:73345	zgc:73345	0.038
ldhba	lactate dehydrogenase Ba	0.037
rtf1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.037
got2a	glutamic-oxaloacetic transaminase 2a, mitochondrial (aspartate aminotransferase 2)	0.037
esd	esterase D/formylglutathione hydrolase	0.035
mcm3l	MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like	0.035
mfn2	mitofusin 2	0.034
crfb4	cytokine receptor family member b4	0.033
ptena	phosphatase and tensin homolog A	0.033
si:dkey-21n12.1	si:dkey-21n12.1	0.032
bon	bonnie and clyde	0.032
zgc:112421	zgc:112421	0.031
slc24a5	solute carrier family 24, member 5	0.030
tmem14c	transmembrane protein 14C	0.030
zgc:113210	zgc:113210	0.030
mpz	myelin protein zero	0.030
epb41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.029
zgc:110256	zgc:110256	0.028
mdh1a	malate dehydrogenase 1a, NAD (soluble)	0.027
lmo7a	LIM domain only 7a	0.027
hmbsb	hydroxymethylbilane synthase, b	0.027
brip1	BRCA1 interacting protein C-terminal helicase 1	0.026
obscn	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.025
acadl	acyl-Coenzyme A dehydrogenase, long chain	0.025
si:dkeyp-94b4.2	si:dkeyp-94b4.2	0.024
ca2	carbonic anhydrase II	0.024
edar	ectodysplasin A receptor	0.024
ltk	leukocyte tyrosine kinase	0.023
mapk7	mitogen-activated protein kinase 7	0.022
gstt1b	glutathione S-transferase theta 1b	0.022
ivd	isovaleryl Coenzyme A dehydrogenase	0.022
itga3b	integrin, alpha 3b	0.021
aldh9a1a	aldehyde dehydrogenase 9 family, member A1a	0.021
zgc:55262	zgc:55262	0.021
pcdh1a4	protocadherin 1 alpha 4	0.021
wnt5a	wingless-type MMTV integration site family, member 5a	0.020
zgc:56466	zgc:56466	0.020
pmela	premelanosome protein a	0.020
si:dkey-165n16.1	si:dkey-165n16.1	0.020
zgc:194470	zgc:194470	0.020
tnrc5	trinucleotide repeat containing 5	0.020
msxd	muscle segment homeobox D	0.020
gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.020
agrp	agouti related protein homolog	0.020
lyz	lysozyme	0.020
mapk1	mitogen-activated protein kinase 1	0.019
atp5g	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9)	0.019
LOC565256	similar to Metabotropic glutamate receptor 3 precursor (mGluR3)	0.019
slc30a6	solute carrier family 30 (zinc transporter), member 6	0.019
fam20b	family with sequence similarity 20, member B (H. sapiens)	0.019
fancb	Fanconi anemia, complementation group B	0.018
slc4a1a	solute carrier family 4, anion exchanger, member 1a	0.018
sdr16c5b	short chain dehydrogenase/reductase family 16C, member 5b	0.018
zgc:112986	zgc:112986	0.018
eif2c3	eukaryotic translation initiation factor 2C, 3	0.018
hsd17b10	hydroxysteroid (17-beta) dehydrogenase 10	0.017
csnk1g2a	casein kinase 1, gamma 2a	0.017
slc39a3	solute carrier family 39 (zinc transporter), member 3	0.017
prdx3	peroxiredoxin 3	0.017
ppp1r7	protein phosphatase 1, regulatory (inhibitor) subunit 7	0.017
nccrp1	nonspecific cytotoxic cell receptor protein 1	0.017
coq3	coenzyme Q3 homolog, methyltransferase (yeast)	0.017
stat3	signal transduction and activation of transcription 3	0.017
ociad1	OCIA domain containing 1	0.017
hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase	0.017
brca2	breast cancer 2, early onset	0.017
ppp2r5eb	protein phosphatase 2, regulatory subunit B', epsilon isoform b	0.017
zgc:162944	zgc:162944	0.016
irg1l	immunoresponsive gene 1, like	0.016
comta	catechol-O-methyltransferase a	0.016
dera	2-deoxyribose-5-phosphate aldolase homolog (C. elegans)	0.016
aco1	aconitase 1, soluble	0.016
pccb	propionyl Coenzyme A carboxylase, beta polypeptide	0.016
bida	BH3 interacting domain death agonist	0.016
slc25a43	solute carrier family 25, member 43	0.016
pmch	pro-melanin concentrating hormone	0.016
pgm1	phosphoglucomutase 1	0.015
irf7	interferon regulatory factor 7	0.015
si:ch211-207i1.2	si:ch211-207i1.2	0.015
col17a1b	collagen, type XVII, alpha 1b	0.015
plxnb2b	plexin b2b	0.015
si:dkey-250d21.1	si:dkey-250d21.1	0.015
hs3st1l1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1-like1	0.015
mtm1	myotubularin 1	0.015
slc30a7	solute carrier family 30 (zinc transporter), member 7	0.015
cdh23	cadherin-like 23	0.015
LOC570775	protein argonaute-1-like	0.015
esf1	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)	0.015
zgc:110010	zgc:110010	0.014
ube2i2	ubiquitin-conjugating enzyme E2I2	0.014
znf711	zinc finger protein 711	0.014
si:dkey-88p24.9	si:dkey-88p24.9	0.014
arfip1	ADP-ribosylation factor interacting protein 1 (arfaptin 1)	0.014
dlat	dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)	0.014
osbpl2	oxysterol binding protein-like 2	0.014
si:dkeyp-27b10.2	si:dkeyp-27b10.2	0.014
papolb	poly(A) polymerase beta (testis specific)	0.014
si:dkey-110c1.1	si:dkey-110c1.1	0.014
zgc:56518	zgc:56518	0.014
got2b	glutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2)	0.013
mical1	microtubule associated monoxygenase, calponin and LIM domain containing 1	0.013
fbp1a	fructose-1,6-bisphosphatase 1a	0.013
atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.013
bpnt1	bisphosphate nucleotidase 1	0.013
orai1	ORAI calcium release-activated calcium modulator 1	0.013
igfbp6b	insulin-like growth factor binding protein 6b	0.013
ndufv1	NADH dehydrogenase (ubiquinone) flavoprotein 1	0.013
si:dkeyp-51f11.8	si:dkeyp-51f11.8	0.013
rpl13	ribosomal protein L13	0.013
csrp3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.013
ddt	D-dopachrome tautomerase	0.013
lgsn	lengsin, lens protein with glutamine synthetase domain	0.013
adcy5	adenylate cyclase 5	0.013
arf1	ADP-ribosylation factor 1	0.013
tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.013
dkk3	dickkopf homolog 3 (Xenopus laevis)	0.013
vps33b	vacuolar protein sorting 33B	0.013
cat	catalase	0.012
lox	lysyl oxidase	0.012
slc25a44b	solute carrier family 25, member 44 b	0.012
zgc:101030	zgc:101030	0.012
oxsr1a	oxidative-stress responsive 1a	0.012
cmtm4	CKLF-like MARVEL transmembrane domain containing 4	0.012
pcdh1a6	protocadherin 1 alpha 6	0.012
LOC100151531	zinc finger protein Gfi-1b-like	0.012
and2	actinodin2	0.012
si:ch211-89f7.4	si:ch211-89f7.4	0.012
zgc:92763	zgc:92763	0.012
fdx1	ferredoxin 1	0.012
pi4kaa	phosphatidylinositol 4-kinase, catalytic, alpha a	0.012
smtnb	smoothelin b	0.012
tk2	thymidine kinase 2, mitochondrial	0.012
ucp3	uncoupling protein 3	0.012
hopx	HOP homeobox	0.012
tmpoa	thymopoietin a	0.012
rhd	Rh blood group, D antigen	0.012
atp7b	ATPase, Cu++ transporting, beta polypeptide (Wilson disease)	0.012
LOC100000685	similar to OCTN2 protein	0.012
krt1-19d	keratin, type 1, gene 19d	0.011
hsf2	heat shock factor 2	0.011
krt15	keratin 15	0.011
il13ra2	interleukin 13 receptor, alpha 2	0.011
ppfibp2b	protein tyrosine phosphatase, receptor-type, F interacting protein, binding protein 2b	0.011
upf3b	UPF3 regulator of nonsense transcripts homolog B (yeast)	0.011
si:dkeyp-7c9.1	si:dkeyp-7c9.1	0.011
abat	4-aminobutyrate aminotransferase	0.011
glceb	glucuronyl C5-epimerase b	0.011
ecrg4a	esophageal cancer related gene 4a	0.011
cdc42	cell division cycle 42	0.011
naa15b	N(alpha)-acetyltransferase 15, NatA auxiliary subunit b	0.011
ogt.1	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 1	0.011
zgc:158350	zgc:158350	0.011
fstl5	follistatin-like 5 and follistatin-like 5	0.011
slc39a4	solute carrier family 39 (zinc transporter), member 4	0.011
spam1	sperm adhesion molecule 1	0.011
pcbd1	6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)	0.011
fas	Fas (TNF receptor superfamily, member 6)	0.011
itgb1b.2	integrin, beta 1b.2	0.011
mid1ip1b	MID1 interacting protein 1b	0.011
lgals3l	lectin, galactoside-binding, soluble, 3 (galectin 3)-like	0.011
cdc16	cell division cycle 16 homolog (S. cerevisiae)	0.011
wasa	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a	0.011
cyp19a1b	cytochrome P450, family 19, subfamily A, polypeptide 1b	0.010
gnmt	glycine N-methyltransferase	0.010
cyp2p9	cytochrome P450, family 2, subfamily P, polypeptide 9	0.010
mycbp2	MYC binding protein 2	0.010
wars	tryptophanyl-tRNA synthetase	0.010
slc35b2	solute carrier family 35, member B2	0.010
rps6ka1	ribosomal protein S6 kinase a, polypeptide 1	0.010
gstm	glutathione S-transferase M	0.010
lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.010
zgc:92745	zgc:92745	0.010
LOC100002448	macrophage-stimulating protein receptor-like	0.010
slc6a4b	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4B	0.010
zgc:92630	zgc:92630	0.010