The network for 'nephron epithelium development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

nephron epithelium development

The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron.

Drosophila melanogaster
Name Description Probability Func Analog Organism
ci cubitus interruptus 0.994
Egfr Epidermal growth factor receptor 0.978
wg wingless 0.961
E(spl) Enhancer of split 0.864
hth homothorax 0.807
HLHm7 E(spl) region transcript m7 0.755
HLHmdelta E(spl) region transcript mdelta 0.722
HLHm3 E(spl) region transcript m3 0.705
Mad Mothers against dpp 0.701
tkv thickveins 0.700
fng fringe 0.692
bowl brother of odd with entrails limited 0.688
en engrailed 0.611
HLHmgamma E(spl) region transcript mgamma 0.611
H Hairless 0.607
Ubx Ultrabithorax 0.599
argos CG4531 gene product from transcript CG4531-RA 0.584
m2 E(spl) region transcript m2 0.554
Tom Twin of m4 0.546
Ser Serrate 0.529
HLHmbeta E(spl) region transcript mbeta 0.507
Antp Antennapedia 0.483
bib big brain 0.458
kni knirps 0.392
malpha E(spl) region transcript malpha 0.391
opa odd paired 0.378
nmo nemo 0.291
twi twist 0.285
os outstretched 0.278
odd odd skipped 0.277
dac dachshund 0.272
LanB2 Laminin B2 0.272
eya eyes absent 0.269
klu klumpfuss 0.247
noc no ocelli 0.244
tup tailup 0.242
rst roughest 0.239
bi bifid 0.236
aop anterior open 0.235
hh hedgehog 0.232
vg vestigial 0.229
Dfd Deformed 0.209
sog short gastrulation 0.201
18w 18 wheeler 0.195
brk brinker 0.195
ato atonal 0.187
sd scalloped 0.183
gcm glial cells missing 0.181
scw screw 0.177
disco disconnected 0.172
inv invected 0.170
btd buttonhead 0.166
sna snail 0.163
Ssdp Sequence-specific single-stranded DNA-binding protein 0.146
byn brachyenteron 0.140
loqs loquacious 0.138
ptc patched 0.137
sc scute 0.135
elav embryonic lethal abnormal vision 0.134
eg eagle 0.132
egh egghead 0.130
hpo hippo 0.130
dm diminutive 0.129
RhoGAP100F CG1976 gene product from transcript CG1976-RB 0.125
oc ocelliless 0.120
Fas2 Fasciclin 2 0.118
wb wing blister 0.116
HLHm5 E(spl) region transcript m5 0.114
B-H1 BarH1 0.113
sns sticks and stones 0.113
stck steamer duck 0.112
zfh1 Zn finger homeodomain 1 0.111
pcs parcas 0.110
emc extra macrochaetae 0.109
sbb scribbler 0.107
shn schnurri 0.105
ac achaete 0.103
htl heartless 0.103
tsh teashirt 0.102
ed echinoid 0.101
SoxN SoxNeuro 0.101
pnr pannier 0.099
fas faint sausage 0.097
ss spineless 0.096
so sine oculis 0.095
ems empty spiracles 0.093
CG3563 CG3563 gene product from transcript CG3563-RA 0.093
Gsc Goosecoid 0.091
pll pelle 0.087
ey eyeless 0.086
kn knot 0.085
Fas3 Fasciclin 3 0.083
Dad Daughters against dpp 0.083
sca scabrous 0.083
klar klarsicht 0.082
amos absent MD neurons and olfactory sensilla 0.081
rho rhomboid 0.078
pcx pecanex 0.077
al aristaless 0.077
put punt 0.077
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
pax2a paired box gene 2a 0.998
tbx1 T-box 1 0.939
osr2 odd-skipped related 2 (Drosophila) 0.847
hnf1ba HNF1 homeobox Ba 0.803
wt1b wilms tumor 1b 0.769
lhx1a LIM homeobox 1a 0.764
bmp4 bone morphogenetic protein 4 0.754
kdrl kinase insert domain receptor like 0.741
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.712
dla deltaA 0.674
wt1a wilms tumor 1a 0.564
notch3 notch homolog 3 0.557
bmp2b bone morphogenetic protein 2b 0.529
mecom MDS1 and EVI1 complex locus 0.481
shha sonic hedgehog a 0.438
six4b sine oculis homeobox homolog 4b 0.422
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.395
foxn4 forkhead box N4 0.374
neurog1 neurogenin 1 0.368
dlc deltaC 0.365
eya1 eyes absent homolog 1 0.357
osr1 odd-skipped related 1 (Drosophila) 0.356
gdnf glial cell derived neurotrophic factor 0.350
prdm1a PR domain containing 1a, with ZNF domain 0.334
gli1 GLI-Kruppel family member 1 0.318
foxd3 forkhead box D3 0.313
fli1a friend leukemia integration 1a 0.305
etv2 ets variant gene 2 0.291
fgf8a fibroblast growth factor 8 a 0.290
wnt5b wingless-type MMTV integration site family, member 5b 0.286
pitx3 paired-like homeodomain transcription factor 3 0.274
foxc1a forkhead box C1a 0.270
her12 hairy-related 12 0.264
cdh2 cadherin 2, neuronal 0.262
bmp2a bone morphogenetic protein 2a 0.249
podxl podocalyxin-like 0.239
aplnrb apelin receptor b 0.238
jag1b jagged 1b 0.186
znf503 zinc finger protein 503 0.185
wtip Wilms tumor 1 interacting protein 0.168
hnf1bb HNF1 homeobox Bb 0.166
nphs2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.165
pax8 paired box gene 8 0.155
emx1 empty spiracles homeobox 1 0.152
hoxa9a homeo box A9a 0.141
sall1a sal-like 1a (Drosophila) 0.138
hoxd12a homeo box D12a 0.136
pea3 ETS-domain transcription factor pea3 0.136
nphs1l nephrosis 1, congenital, Finnish type (nephrin)-like 0.135
emx3 empty spiracles homeobox 3 0.130
wnt10a wingless-type MMTV integration site family, member 10a 0.129
hbae1 hemoglobin alpha embryonic-1 0.128
jag2 jagged 2 0.126
notch1a notch homolog 1a 0.116
wnt1 wingless-type MMTV integration site family, member 1 0.113
myod1 myogenic differentiation 1 0.112
flr fleer 0.109
nkx3.2 NK3 homeobox 2 0.106
wnt2ba wingless-type MMTV integration site family, member 2Ba 0.103
cdx4 caudal type homeo box transcription factor 4 0.102
rfx2 regulatory factor X, 2 (influences HLA class II expression) 0.102
hbbe1.1 hemoglobin beta embryonic-1.1 0.096
gyltl1b glycosyltransferase-like 1b 0.095
alcamb activated leukocyte cell adhesion molecule b 0.094
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.092
adipoql adiponectin, C1Q and collagen domain containing, like 0.091
hoxa9b homeo box A9b 0.087
smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 0.085
neurod4 neurogenic differentiation 4 0.084
gata1a GATA binding protein 1a 0.084
onecutl one cut domain, family member, like 0.080
flncb filamin C, gamma b (actin binding protein 280) 0.077
mib mind bomb 0.077
boc brother of CDO 0.069
foxp2 forkhead box P2 0.068
tfap2a transcription factor AP-2 alpha 0.068
hoxd4a homeo box D4a 0.067
wls wntless homolog (Drosophila) 0.065
ren renin 0.064
sox2 SRY-box containing gene 2 0.062
notch1b notch homolog 1b 0.060
gli2a GLI-Kruppel family member GLI2a 0.060
vegfaa vascular endothelial growth factor Aa 0.059
LOC567452 G protein-coupled receptor kinase 5-like 0.059
hoxd3a homeo box D3a 0.059
gbx2 gastrulation brain homeo box 2 0.058
igfbp3 insulin-like growth factor binding protein 3 0.058
sim1a single-minded homolog 1a (Drosophila) 0.058
cobl cordon-bleu homolog (mouse) 0.056
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.056
hoxb2a homeo box B2a 0.055
hoxd13a homeo box D13a 0.055
tbx18 T-box 18 0.054
pou3f3b POU class 3 homeobox 3b 0.053
six2a sine oculis-related homeobox 2a 0.052
plce1 phospholipase C, epsilon 1 0.051
lamc1 laminin, gamma 1 0.050
hoxa13b homeo box A13b 0.050
mafl v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein L 0.050
her8a hairy-related 8a 0.048
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Homo sapiens
Name Description Probability Func Analog Organism
NOTCH1 notch 1 0.999
FGFR2 fibroblast growth factor receptor 2 0.999
JAG1 jagged 1 0.984
SMAD3 SMAD family member 3 0.930
VEGFA vascular endothelial growth factor A 0.928
NOTCH3 notch 3 0.923
FGF1 fibroblast growth factor 1 (acidic) 0.908
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.889
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.809
CUL3 cullin 3 0.769
NRP1 neuropilin 1 0.662
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.614
KLHL3 kelch-like 3 (Drosophila) 0.576
EGR3 early growth response 3 0.576
ADRB1 adrenergic, beta-1-, receptor 0.553
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.547
FGFR1 fibroblast growth factor receptor 1 0.435
MEIS1 Meis homeobox 1 0.429
WNK4 WNK lysine deficient protein kinase 4 0.399
MEIS2 Meis homeobox 2 0.384
ADAM17 ADAM metallopeptidase domain 17 0.372
TSC22D4 TSC22 domain family, member 4 0.365
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.325
FGF10 fibroblast growth factor 10 0.290
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.283
COL2A1 collagen, type II, alpha 1 0.256
NKX2-1 NK2 homeobox 1 0.241
DPYSL4 dihydropyrimidinase-like 4 0.236
FGF8 fibroblast growth factor 8 (androgen-induced) 0.220
SOX2 SRY (sex determining region Y)-box 2 0.211
KLHL12 kelch-like 12 (Drosophila) 0.208
FGF18 fibroblast growth factor 18 0.202
FSTL1 follistatin-like 1 0.199
MDFI MyoD family inhibitor 0.198
LAPTM5 lysosomal protein transmembrane 5 0.196
TCF4 transcription factor 4 0.188
DAPK1 death-associated protein kinase 1 0.184
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.180
NOTCH2 notch 2 0.173
HOXA10 homeobox A10 0.164
HOXB5 homeobox B5 0.162
CDC25B cell division cycle 25 homolog B (S. pombe) 0.159
MEOX1 mesenchyme homeobox 1 0.146
CCNE1 cyclin E1 0.144
TIMP3 TIMP metallopeptidase inhibitor 3 0.135
MSN moesin 0.130
KLHL2 kelch-like 2, Mayven (Drosophila) 0.116
SKIL SKI-like oncogene 0.113
ENG endoglin 0.110
BMP7 bone morphogenetic protein 7 0.106
FGF4 fibroblast growth factor 4 0.105
MAML1 mastermind-like 1 (Drosophila) 0.099
MAGED2 melanoma antigen family D, 2 0.098
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.091
GLIS2 GLIS family zinc finger 2 0.089
PAX8 paired box 8 0.087
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) 0.085
JAG2 jagged 2 0.080
EGR2 early growth response 2 0.073
PJA1 praja ring finger 1 0.071
BMP2 bone morphogenetic protein 2 0.070
DLL1 delta-like 1 (Drosophila) 0.070
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.069
PARVA parvin, alpha 0.069
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.068
BMP4 bone morphogenetic protein 4 0.068
NGFR nerve growth factor receptor 0.064
HDAC4 histone deacetylase 4 0.063
SH3GL3 SH3-domain GRB2-like 3 0.060
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.060
PRMT6 protein arginine methyltransferase 6 0.059
BCAM basal cell adhesion molecule (Lutheran blood group) 0.056
HMGA1 high mobility group AT-hook 1 0.055
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.052
HDAC9 histone deacetylase 9 0.046
TRPV5 transient receptor potential cation channel, subfamily V, member 5 0.044
PDGFA platelet-derived growth factor alpha polypeptide 0.044
TGFB3 transforming growth factor, beta 3 0.044
THBS1 thrombospondin 1 0.044
EGR1 early growth response 1 0.043
ZNF512B zinc finger protein 512B 0.042
TGFB2 transforming growth factor, beta 2 0.041
SOX1 SRY (sex determining region Y)-box 1 0.041
PAX2 paired box 2 0.041
DSCAML1 Down syndrome cell adhesion molecule like 1 0.041
SFRP1 secreted frizzled-related protein 1 0.040
INHBB inhibin, beta B 0.039
WNT1 wingless-type MMTV integration site family, member 1 0.038
PDX1 pancreatic and duodenal homeobox 1 0.037
SOX9 SRY (sex determining region Y)-box 9 0.036
COL6A1 collagen, type VI, alpha 1 0.035
HMGA2 high mobility group AT-hook 2 0.034
FGF3 fibroblast growth factor 3 0.033
IRX4 iroquois homeobox 4 0.033
CLDN4 claudin 4 0.032
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.032
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.031
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.031
OXSR1 oxidative-stress responsive 1 0.030
ATXN1L ataxin 1-like 0.030
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Mus musculus
Name Description Probability Func Analog Organism
Wt1 Wilms tumor 1 homolog 0.999
Pax2 paired box gene 2 0.999
Lhx1 LIM homeobox protein 1 0.998
Fgfr2 fibroblast growth factor receptor 2 0.998
Foxc1 forkhead box C1 0.996
Emx2 empty spiracles homolog 2 (Drosophila) 0.994
Gli3 GLI-Kruppel family member GLI3 0.994
Nos3 nitric oxide synthase 3, endothelial cell 0.994
Pax8 paired box gene 8 0.991
Hoxa11 homeobox A11 0.989
Gata4 GATA binding protein 4 0.985
Bcl2 B-cell leukemia/lymphoma 2 0.982
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.978
Ren1 renin 1 structural 0.971
Pax6 paired box gene 6 0.971
Gli2 GLI-Kruppel family member GLI2 0.969
Shh sonic hedgehog 0.968
Hes1 hairy and enhancer of split 1 (Drosophila) 0.966
Gdnf glial cell line derived neurotrophic factor 0.959
Pax3 paired box gene 3 0.958
Notch1 Notch gene homolog 1 (Drosophila) 0.945
Jag1 jagged 1 0.939
Lmx1a LIM homeobox transcription factor 1 alpha 0.937
Ret ret proto-oncogene 0.934
Hoxd11 homeobox D11 0.931
Sox2 SRY-box containing gene 2 0.928
Ctnnb1 catenin (cadherin associated protein), beta 1 0.917
Gata6 GATA binding protein 6 0.916
Smad6 MAD homolog 6 (Drosophila) 0.910
Rarg retinoic acid receptor, gamma 0.910
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.894
Sox7 SRY-box containing gene 7 0.888
Tbx2 T-box 2 0.887
Foxc2 forkhead box C2 0.882
Hes5 hairy and enhancer of split 5 (Drosophila) 0.880
Pitx2 paired-like homeodomain transcription factor 2 0.878
Otx2 orthodenticle homolog 2 (Drosophila) 0.869
Otx1 orthodenticle homolog 1 (Drosophila) 0.861
Wnt4 wingless-related MMTV integration site 4 0.860
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.852
Hoxa2 homeobox A2 0.850
Lamc1 laminin, gamma 1 0.838
Fgfr1 fibroblast growth factor receptor 1 0.818
Pbx1 pre B-cell leukemia transcription factor 1 0.811
Lhx3 LIM homeobox protein 3 0.800
Smad3 MAD homolog 3 (Drosophila) 0.795
Fgf8 fibroblast growth factor 8 0.790
Vegfa vascular endothelial growth factor A 0.790
Slc12a1 solute carrier family 12, member 1 0.770
Hoxd9 homeobox D9 0.751
Eya1 eyes absent 1 homolog (Drosophila) 0.741
Snai1 snail homolog 1 (Drosophila) 0.733
Foxa2 forkhead box A2 0.728
Pkd1 polycystic kidney disease 1 homolog 0.725
Nog noggin 0.721
Foxf1a forkhead box F1a 0.714
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.706
Hmx3 H6 homeobox 3 0.703
Nkx2-1 NK2 homeobox 1 0.695
Emx1 empty spiracles homolog 1 (Drosophila) 0.690
Bnc1 basonuclin 1 0.687
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.672
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.670
Hoxb4 homeobox B4 0.658
Hoxa1 homeobox A1 0.653
Hoxb6 homeobox B6 0.647
Hand2 heart and neural crest derivatives expressed transcript 2 0.637
Wnt6 wingless-related MMTV integration site 6 0.630
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.630
Pou3f3 POU domain, class 3, transcription factor 3 0.628
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.628
Bmp4 bone morphogenetic protein 4 0.624
Tead3 TEA domain family member 3 0.615
Hoxd3 homeobox D3 0.609
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.606
Hoxb5 homeobox B5 0.606
Hoxd13 homeobox D13 0.594
Tbx3 T-box 3 0.589
Col4a3 collagen, type IV, alpha 3 0.588
Hoxa13 homeobox A13 0.570
Dll1 delta-like 1 (Drosophila) 0.548
Mks1 Meckel syndrome, type 1 0.544
Pten phosphatase and tensin homolog 0.531
Ar androgen receptor 0.520
Efna2 ephrin A2 0.505
Meox2 mesenchyme homeobox 2 0.498
Hoxd10 homeobox D10 0.489
En1 engrailed 1 0.488
Foxd2 forkhead box D2 0.485
Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 0.480
Hoxc8 homeobox C8 0.477
Tlx3 T-cell leukemia, homeobox 3 0.471
Gas1 growth arrest specific 1 0.470
Hoxa10 homeobox A10 0.468
Rara retinoic acid receptor, alpha 0.464
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.462
Zfp503 zinc finger protein 503 0.461
Foxh1 forkhead box H1 0.461
Vax1 ventral anterior homeobox containing gene 1 0.456
C1qc complement component 1, q subcomponent, C chain 0.456
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Rattus norvegicus
Name Description Probability Func Analog Organism
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.040
Idi1 isopentenyl-diphosphate delta isomerase 1 0.037
Gja5 gap junction protein, alpha 5 0.028
Baiap2 BAI1-associated protein 2 0.027
LOC100365106 rCG32755-like 0.025
Flt1 FMS-related tyrosine kinase 1 0.024
Cyp51 cytochrome P450, family 51 0.023
Bcl2 B-cell CLL/lymphoma 2 0.020
Myh9 myosin, heavy chain 9, non-muscle 0.019
Hoxc4 homeo box C4 0.018
Lepr leptin receptor 0.017
Aif1l allograft inflammatory factor 1-like 0.014
Krt15 keratin 15 0.014
Irf2 interferon regulatory factor 2 0.013
Acacb acetyl-Coenzyme A carboxylase beta 0.013
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.012
Adrb1 adrenergic, beta-1-, receptor 0.012
Sqle squalene epoxidase 0.012
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.012
Cxxc4 CXXC finger 4 0.012
LOC100362108 poly (ADP-ribose) polymerase family, member 10 0.011
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.011
Rps6ka1 ribosomal protein S6 kinase polypeptide 1 0.011
Smad7 SMAD family member 7 0.011
Rara retinoic acid receptor, alpha 0.011
Rnf213 ring finger protein 213 0.011
Insrr insulin receptor-related receptor 0.011
Limd1 LIM domains containing 1 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism