IMP
Process View
The network for 'actin crosslink formation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
actin crosslink formation
The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| FN1 | fibronectin 1 | 0.683 | |
| FLNA | filamin A, alpha | 0.665 | |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.516 | |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.470 | |
| WASF2 | WAS protein family, member 2 | 0.466 | |
| FLNB | filamin B, beta | 0.431 | |
| PSEN1 | presenilin 1 | 0.361 | |
| ACTN4 | actinin, alpha 4 | 0.300 | |
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.177 | |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) | 0.121 | |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.063 | |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | 0.059 | |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.057 | |
| ACTN1 | actinin, alpha 1 | 0.056 | |
| TLN1 | talin 1 | 0.053 | |
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.044 | |
| BAIAP2 | BAI1-associated protein 2 | 0.042 | |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.039 | |
| ABI1 | abl-interactor 1 | 0.033 | |
| ZYX | zyxin | 0.027 | |
| PLEC | plectin | 0.026 | |
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.026 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.026 | |
| FBLIM1 | filamin binding LIM protein 1 | 0.025 | |
| ITGB4 | integrin, beta 4 | 0.021 | |
| FHL2 | four and a half LIM domains 2 | 0.018 | |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.016 | |
| NCKAP1 | NCK-associated protein 1 | 0.015 | |
| ITGB5 | integrin, beta 5 | 0.015 | |
| ITGB7 | integrin, beta 7 | 0.013 | |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.012 | |
| PKP4 | plakophilin 4 | 0.012 | |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 0.012 | |
| XIRP1 | xin actin-binding repeat containing 1 | 0.011 | |
| ATN1 | atrophin 1 | 0.010 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Tagln | transgelin | 0.248 | |
| Actn1 | actinin, alpha 1 | 0.182 | |
| Vim | vimentin | 0.153 | |
| Iqgap1 | IQ motif containing GTPase activating protein 1 | 0.132 | |
| Myh9 | myosin, heavy chain 9, non-muscle | 0.121 | |
| Mylpf | myosin light chain, phosphorylatable, fast skeletal muscle | 0.097 | |
| Acta2 | smooth muscle alpha-actin | 0.081 | |
| Lmna | lamin A | 0.078 | |
| Tpm2 | tropomyosin 2, beta | 0.078 | |
| Tagln2 | transgelin 2 | 0.071 | |
| Plxnb2 | plexin B2 | 0.070 | |
| Ahnak | AHNAK nucleoprotein | 0.064 | |
| Ina | internexin neuronal intermediate filament protein, alpha | 0.054 | |
| Csrp1 | cysteine and glycine-rich protein 1 | 0.048 | |
| Tln1 | talin 1 | 0.047 | |
| Map4k4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.047 | |
| Magi2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.045 | |
| Lamc1 | laminin, gamma 1 | 0.042 | |
| Atp2a1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 0.041 | |
| Snd1 | staphylococcal nuclease and tudor domain containing 1 | 0.037 | |
| Myl1 | myosin, light chain 1 | 0.037 | |
| LOC686323 | similar to thyroid receptor-interacting protein 6 | 0.033 | |
| Myl9 | myosin, light chain 9, regulatory | 0.033 | |
| Dlg3 | discs, large homolog 3 (Drosophila) | 0.031 | |
| Pxn | paxillin | 0.031 | |
| Ckm | creatine kinase, muscle | 0.029 | |
| Myadm | myeloid-associated differentiation marker | 0.028 | |
| Ppp1r1a | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 0.028 | |
| Mafk | v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) | 0.027 | |
| Cnksr3 | Cnksr family member 3 | 0.027 | |
| Acta1 | actin, alpha 1, skeletal muscle | 0.026 | |
| Cdh16 | cadherin 16 | 0.026 | |
| Pdzd4 | PDZ domain containing 4 | 0.026 | |
| Fam38a | family with sequence similarity 38, member A | 0.024 | |
| Dmgdh | dimethylglycine dehydrogenase | 0.024 | |
| Pnmal2 | PNMA-like 2 | 0.022 | |
| Tnni2 | troponin I type 2 (skeletal, fast) | 0.021 | |
| Gprin1 | G protein-regulated inducer of neurite outgrowth 1 | 0.021 | |
| Flna | filamin A, alpha | 0.021 | |
| Fam129b | family with sequence similarity 129, member B | 0.021 | |
| Vasp | vasodilator-stimulated phosphoprotein | 0.021 | |
| Armcx2 | armadillo repeat containing, X-linked 2 | 0.020 | |
| Faah | fatty acid amide hydrolase | 0.020 | |
| Slc27a2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.020 | |
| Rtn1 | reticulon 1 | 0.019 | |
| Sncb | synuclein, beta | 0.019 | |
| Lin7b | lin-7 homolog b (C. elegans) | 0.019 | |
| Mcam | melanoma cell adhesion molecule | 0.018 | |
| Flnc | filamin C, gamma | 0.018 | |
| Nelf | nasal embryonic LHRH factor | 0.018 | |
| Gne | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 0.018 | |
| Il4ra | interleukin 4 receptor, alpha | 0.017 | |
| Gp1bb | glycoprotein Ib (platelet), beta polypeptide | 0.017 | |
| Gprasp1 | G protein-coupled receptor associated sorting protein 1 | 0.016 | |
| Tuba1c | tubulin, alpha 1C | 0.016 | |
| Kif5c | kinesin family member 5C | 0.016 | |
| Actg2 | actin, gamma 2, smooth muscle, enteric | 0.015 | |
| Klkb1 | kallikrein B, plasma 1 | 0.015 | |
| Stx1b | syntaxin 1B | 0.015 | |
| Akap12 | A kinase (PRKA) anchor protein 12 | 0.015 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.015 | |
| Stmn3 | stathmin-like 3 | 0.015 | |
| Pcdha13 | protocadherin alpha 13 | 0.015 | |
| Tubb2b | tubulin, beta 2b | 0.015 | |
| Tspan7 | tetraspanin 7 | 0.014 | |
| Flnb | filamin, beta | 0.014 | |
| Nsg1 | neuron specific gene family member 1 | 0.014 | |
| Lppr3 | lipid phosphate phosphatase-related protein type 3 | 0.014 | |
| Elk3 | ELK3, ETS-domain protein | 0.014 | |
| Matk | megakaryocyte-associated tyrosine kinase | 0.014 | |
| Emilin1 | elastin microfibril interfacer 1 | 0.014 | |
| P2ry2 | purinergic receptor P2Y, G-protein coupled, 2 | 0.014 | |
| Hspb1 | heat shock protein 1 | 0.014 | |
| Traf4af1 | TRAF4 associated factor 1 | 0.014 | |
| Znf598 | zinc finger protein 598 | 0.014 | |
| Trim35 | tripartite motif-containing 35 | 0.014 | |
| Dpysl5 | dihydropyrimidinase-like 5 | 0.013 | |
| L1cam | L1 cell adhesion molecule | 0.013 | |
| Cbln1 | cerebellin 1 precursor | 0.013 | |
| Nptn | neuroplastin | 0.013 | |
| Spock2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2 | 0.013 | |
| Cnih2 | cornichon homolog 2 (Drosophila) | 0.012 | |
| Syp | synaptophysin | 0.012 | |
| Sfxn3 | sideroflexin 3 | 0.012 | |
| Zcchc12 | zinc finger, CCHC domain containing 12 | 0.012 | |
| Kynu | kynureninase (L-kynurenine hydrolase) | 0.012 | |
| Prkar1b | protein kinase, cAMP dependent regulatory, type I, beta | 0.012 | |
| Ril | reversion induced LIM gene | 0.012 | |
| Marcksl1 | MARCKS-like 1 | 0.012 | |
| Myh7 | myosin, heavy chain 7, cardiac muscle, beta | 0.012 | |
| Mobkl2a | MOB1, Mps One Binder kinase activator-like 2A (yeast) | 0.012 | |
| Map4 | microtubule-associated protein 4 | 0.012 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.012 | |
| Ces1e | carboxylesterase 1E | 0.012 | |
| Clip2 | CAP-GLY domain containing linker protein 2 | 0.011 | |
| Mvp | major vault protein | 0.011 | |
| Nsg2 | neuron specific gene family member 2 | 0.011 | |
| Vcan | versican | 0.011 | |
| Ptbp1 | polypyrimidine tract binding protein 1 | 0.011 | |
| Ncam1 | neural cell adhesion molecule 1 | 0.011 |