IMP
Process View
The network for 'negative regulation of potassium ion transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of potassium ion transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.954 | |
| CAB39 | calcium binding protein 39 | 0.363 | |
| ZYX | zyxin | 0.147 | |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.104 | |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.082 | |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.081 | |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.076 | |
| FLNA | filamin A, alpha | 0.071 | |
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.061 | |
| PDLIM1 | PDZ and LIM domain 1 | 0.040 | |
| PDCD6IP | programmed cell death 6 interacting protein | 0.040 | |
| SMAD4 | SMAD family member 4 | 0.038 | |
| RNF11 | ring finger protein 11 | 0.037 | |
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.034 | |
| SMAD1 | SMAD family member 1 | 0.030 | |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.029 | |
| MYOZ1 | myozenin 1 | 0.025 | |
| ANKRD13A | ankyrin repeat domain 13A | 0.025 | |
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.025 | |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.021 | |
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.020 | |
| SMAD5 | SMAD family member 5 | 0.012 | |
| ING2 | inhibitor of growth family, member 2 | 0.011 | |
| FYN | FYN oncogene related to SRC, FGR, YES | 0.010 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.870 | |
| Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.859 | |
| Nos1 | nitric oxide synthase 1, neuronal | 0.841 | |
| Kcna2 | potassium voltage-gated channel, shaker-related subfamily, member 2 | 0.723 | |
| Kcnb1 | potassium voltage gated channel, Shab-related subfamily, member 1 | 0.639 | |
| Grin2b | glutamate receptor, ionotropic, NMDA2B (epsilon 2) | 0.483 | |
| Camk2a | calcium/calmodulin-dependent protein kinase II alpha | 0.411 | |
| Drd2 | dopamine receptor D2 | 0.339 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.320 | |
| Ldb3 | LIM domain binding 3 | 0.276 | |
| Kcna1 | potassium voltage-gated channel, shaker-related subfamily, member 1 | 0.250 | |
| Ryr2 | ryanodine receptor 2, cardiac | 0.235 | |
| Lepr | leptin receptor | 0.214 | |
| Adora2a | adenosine A2a receptor | 0.141 | |
| Prkce | protein kinase C, epsilon | 0.139 | |
| Ren1 | renin 1 structural | 0.111 | |
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.099 | |
| Kcnj3 | potassium inwardly-rectifying channel, subfamily J, member 3 | 0.091 | |
| Esr1 | estrogen receptor 1 (alpha) | 0.089 | |
| Lep | leptin | 0.089 | |
| Ank1 | ankyrin 1, erythroid | 0.087 | |
| Cntn4 | contactin 4 | 0.086 | |
| Ar | androgen receptor | 0.084 | |
| Kcnma1 | potassium large conductance calcium-activated channel, subfamily M, alpha member 1 | 0.084 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.081 | |
| Prkcc | protein kinase C, gamma | 0.077 | |
| Homer1 | homer homolog 1 (Drosophila) | 0.075 | |
| Hrc | histidine rich calcium binding protein | 0.073 | |
| Kcnj11 | potassium inwardly rectifying channel, subfamily J, member 11 | 0.070 | |
| Atp1b2 | ATPase, Na+/K+ transporting, beta 2 polypeptide | 0.065 | |
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.061 | |
| Timp4 | tissue inhibitor of metalloproteinase 4 | 0.060 | |
| Grin2a | glutamate receptor, ionotropic, NMDA2A (epsilon 1) | 0.048 | |
| Nxph1 | neurexophilin 1 | 0.047 | |
| Gabrb2 | gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 | 0.047 | |
| Grm1 | glutamate receptor, metabotropic 1 | 0.046 | |
| Ywhab | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.046 | |
| Vegfa | vascular endothelial growth factor A | 0.045 | |
| Tgfb1 | transforming growth factor, beta 1 | 0.044 | |
| Il10 | interleukin 10 | 0.043 | |
| Tcap | titin-cap | 0.040 | |
| Trpc5 | transient receptor potential cation channel, subfamily C, member 5 | 0.040 | |
| Kcnk3 | potassium channel, subfamily K, member 3 | 0.040 | |
| Pygm | muscle glycogen phosphorylase | 0.037 | |
| Gpr37l1 | G protein-coupled receptor 37-like 1 | 0.037 | |
| Camk2b | calcium/calmodulin-dependent protein kinase II, beta | 0.036 | |
| Dnajb5 | DnaJ (Hsp40) homolog, subfamily B, member 5 | 0.036 | |
| Cav1 | caveolin 1, caveolae protein | 0.035 | |
| Crhr1 | corticotropin releasing hormone receptor 1 | 0.035 | |
| Hcn1 | hyperpolarization-activated, cyclic nucleotide-gated K+ 1 | 0.034 | |
| Cacna1b | calcium channel, voltage-dependent, N type, alpha 1B subunit | 0.034 | |
| Cacna2d1 | calcium channel, voltage-dependent, alpha2/delta subunit 1 | 0.034 | |
| Htr1a | 5-hydroxytryptamine (serotonin) receptor 1A | 0.033 | |
| Rgs6 | regulator of G-protein signaling 6 | 0.033 | |
| Fgf12 | fibroblast growth factor 12 | 0.032 | |
| Vdr | vitamin D receptor | 0.031 | |
| Cacna1g | calcium channel, voltage-dependent, T type, alpha 1G subunit | 0.030 | |
| Srpk3 | serine/arginine-rich protein specific kinase 3 | 0.029 | |
| Mpp3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) | 0.028 | |
| Npy5r | neuropeptide Y receptor Y5 | 0.027 | |
| Sult4a1 | sulfotransferase family 4A, member 1 | 0.026 | |
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.026 | |
| Atp1a2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.025 | |
| Slc12a5 | solute carrier family 12, member 5 | 0.024 | |
| Cacna2d3 | calcium channel, voltage-dependent, alpha2/delta subunit 3 | 0.024 | |
| Cnr1 | cannabinoid receptor 1 (brain) | 0.023 | |
| Actn2 | actinin alpha 2 | 0.023 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.023 | |
| Asap1 | ArfGAP with SH# domain, ankyrin repeat and PH domain1 | 0.023 | |
| Kcna4 | potassium voltage-gated channel, shaker-related subfamily, member 4 | 0.023 | |
| Kcnc1 | potassium voltage gated channel, Shaw-related subfamily, member 1 | 0.022 | |
| Zfp651 | zinc finger protein 651 | 0.022 | |
| Npy2r | neuropeptide Y receptor Y2 | 0.022 | |
| Tcf15 | transcription factor 15 | 0.022 | |
| Kcnh1 | potassium voltage-gated channel, subfamily H (eag-related), member 1 | 0.021 | |
| Syn2 | synapsin II | 0.021 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.021 | |
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.020 | |
| Fgf14 | fibroblast growth factor 14 | 0.020 | |
| Ntrk3 | neurotrophic tyrosine kinase, receptor, type 3 | 0.020 | |
| Gabra1 | gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 | 0.020 | |
| Mmp9 | matrix metallopeptidase 9 | 0.020 | |
| Trpc4 | transient receptor potential cation channel, subfamily C, member 4 | 0.019 | |
| Kcnd2 | potassium voltage-gated channel, Shal-related family, member 2 | 0.018 | |
| Accn1 | amiloride-sensitive cation channel 1, neuronal (degenerin) | 0.018 | |
| Kcnj12 | potassium inwardly-rectifying channel, subfamily J, member 12 | 0.018 | |
| Slc12a1 | solute carrier family 12, member 1 | 0.017 | |
| Mybpc3 | myosin binding protein C, cardiac | 0.017 | |
| Dtna | dystrobrevin alpha | 0.017 | |
| Ldlr | low density lipoprotein receptor | 0.017 | |
| Npas2 | neuronal PAS domain protein 2 | 0.017 | |
| Myh6 | myosin, heavy polypeptide 6, cardiac muscle, alpha | 0.017 | |
| Phkg1 | phosphorylase kinase gamma 1 | 0.017 | |
| Mmp16 | matrix metallopeptidase 16 | 0.016 | |
| Dlg2 | discs, large homolog 2 (Drosophila) | 0.016 | |
| Wnk4 | WNK lysine deficient protein kinase 4 | 0.016 | |
| Slc12a2 | solute carrier family 12, member 2 | 0.016 | |
| Smad3 | MAD homolog 3 (Drosophila) | 0.016 | |
| Plp1 | proteolipid protein (myelin) 1 | 0.015 | |
| Kcnj5 | potassium inwardly-rectifying channel, subfamily J, member 5 | 0.015 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Cav1 | caveolin 1, caveolae protein | 0.254 | |
| LOC100362824 | caveolin 2-like | 0.174 | |
| Cav2 | caveolin 2 | 0.091 | |
| Strn | striatin, calmodulin binding protein | 0.040 | |
| Olr416 | olfactory receptor 416 | 0.033 | |
| Myo1d | myosin ID | 0.032 | |
| Adora3 | adenosine A3 receptor | 0.026 | |
| Vat1 | vesicle amine transport protein 1 homolog (T californica) | 0.024 | |
| Tacr3 | tachykinin receptor 3 | 0.023 | |
| Gria1 | glutamate receptor, ionotropic, AMPA 1 | 0.023 | |
| Syt4 | synaptotagmin IV | 0.019 | |
| Oprd1 | opioid receptor, delta 1 | 0.017 | |
| Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.016 | |
| Grik3 | glutamate receptor, ionotropic, kainate 3 | 0.015 | |
| Ppp1r15a | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 0.014 | |
| Ttl | tubulin tyrosine ligase | 0.013 | |
| Sstr5 | somatostatin receptor 5 | 0.012 | |
| Hoxa2 | homeo box A2 | 0.012 | |
| Fermt2 | fermitin family homolog 2 (Drosophila) | 0.012 | |
| Ccbp2 | chemokine binding protein 2 | 0.012 | |
| Prp15 | proline-rich protein 15 | 0.011 | |
| Csrp3 | cysteine and glycine-rich protein 3 | 0.011 | |
| Tgfb1 | transforming growth factor, beta 1 | 0.011 | |
| Gja3 | gap junction protein, alpha 3 | 0.011 | |
| Pld2 | phospholipase D2 | 0.010 | |
| App | amyloid beta (A4) precursor protein | 0.010 | |
| Ehd2 | EH-domain containing 2 | 0.010 | |
| Kcnq3 | potassium voltage-gated channel, KQT-like subfamily, member 3 | 0.010 |