The network for 'positive regulation of nfat protein import into nucleus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of nfat protein import into nucleus

Any process that activates or increases the frequency, rate or extent of the movement of an NFAT protein from the cytoplasm to the nucleus.

Mus musculus
Name Description Probability Func Analog Organism
Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform 0.774
Map3k5 mitogen-activated protein kinase kinase kinase 5 0.539
Kif20a kinesin family member 20A 0.528
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) 0.489
Stim2 stromal interaction molecule 2 0.478
Kif2c kinesin family member 2C 0.465
Kif4 kinesin family member 4 0.442
Cdk1 cyclin-dependent kinase 1 0.433
Ccnb1 cyclin B1 0.299
Kpna1 karyopherin (importin) alpha 1 0.284
Gspt1 G1 to S phase transition 1 0.248
Ckap2 cytoskeleton associated protein 2 0.245
Cep55 centrosomal protein 55 0.243
Stim1 stromal interaction molecule 1 0.238
Birc5 baculoviral IAP repeat-containing 5 0.221
Ccnb2 cyclin B2 0.215
Caprin1 cell cycle associated protein 1 0.214
Usp9x ubiquitin specific peptidase 9, X chromosome 0.201
Tacc3 transforming, acidic coiled-coil containing protein 3 0.162
Kif22 kinesin family member 22 0.159
Kif11 kinesin family member 11 0.148
Racgap1 Rac GTPase-activating protein 1 0.142
Ccna2 cyclin A2 0.136
Top2a topoisomerase (DNA) II alpha 0.135
Cul3 cullin 3 0.132
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.116
Lancl2 LanC (bacterial lantibiotic synthetase component C)-like 2 0.107
Anln anillin, actin binding protein 0.105
Mapk1 mitogen-activated protein kinase 1 0.099
Ipo5 importin 5 0.097
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.091
Nde1 nuclear distribution gene E homolog 1 (A nidulans) 0.088
Kif2a kinesin family member 2A 0.088
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.074
Opa1 optic atrophy 1 homolog (human) 0.072
Mef2a myocyte enhancer factor 2A 0.072
Hnrnpab heterogeneous nuclear ribonucleoprotein A/B 0.068
Topbp1 topoisomerase (DNA) II binding protein 1 0.064
Trim59 tripartite motif-containing 59 0.063
Cks2 CDC28 protein kinase regulatory subunit 2 0.062
Ulk2 Unc-51 like kinase 2 (C. elegans) 0.062
Zc3h14 zinc finger CCCH type containing 14 0.060
Usp24 ubiquitin specific peptidase 24 0.060
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.059
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.058
Spast spastin 0.057
Ncaph non-SMC condensin I complex, subunit H 0.056
Sos2 son of sevenless homolog 2 (Drosophila) 0.054
Wbp11 WW domain binding protein 11 0.053
Cand1 cullin associated and neddylation disassociated 1 0.053
Aurka aurora kinase A 0.051
Mtmr6 myotubularin related protein 6 0.046
Lbr lamin B receptor 0.045
Akap5 A kinase (PRKA) anchor protein 5 0.045
Pbk PDZ binding kinase 0.045
Hnrnpm heterogeneous nuclear ribonucleoprotein M 0.042
Sec23a SEC23A (S. cerevisiae) 0.040
Pom121 nuclear pore membrane protein 121 0.039
Pds5b PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) 0.038
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.038
Lsm2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.037
Bub1 budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) 0.036
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.036
Spag5 sperm associated antigen 5 0.036
Cdca8 cell division cycle associated 8 0.034
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.033
Usp45 ubiquitin specific petidase 45 0.033
Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.033
Kpna2 karyopherin (importin) alpha 2 0.033
Nupl1 nucleoporin like 1 0.031
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.031
Cdc7 cell division cycle 7 (S. cerevisiae) 0.031
Ddx46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.030
Gnl2 guanine nucleotide binding protein-like 2 (nucleolar) 0.029
Cdc25c cell division cycle 25 homolog C (S. pombe) 0.029
Ttk Ttk protein kinase 0.028
Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 0.028
Hmgb2 high mobility group box 2 0.027
Snx13 sorting nexin 13 0.026
Mib1 mindbomb homolog 1 (Drosophila) 0.026
Plk1 polo-like kinase 1 (Drosophila) 0.026
Fam98a family with sequence similarity 98, member A 0.026
Metap1 methionyl aminopeptidase 1 0.026
Ppp6c protein phosphatase 6, catalytic subunit 0.026
Aurkb aurora kinase B 0.026
Rock2 Rho-associated coiled-coil containing protein kinase 2 0.025
Trim23 tripartite motif-containing 23 0.025
Ppm1b protein phosphatase 1B, magnesium dependent, beta isoform 0.025
Ssrp1 structure specific recognition protein 1 0.024
D2Ertd750e DNA segment, Chr 2, ERATO Doi 750, expressed 0.023
Ppif peptidylprolyl isomerase F (cyclophilin F) 0.023
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.023
Pcid2 PCI domain containing 2 0.023
Mki67 antigen identified by monoclonal antibody Ki 67 0.023
Ccdc99 coiled-coil domain containing 99 0.022
Usp15 ubiquitin specific peptidase 15 0.022
Pdpk1 3-phosphoinositide dependent protein kinase 1 0.021
Cnot7 CCR4-NOT transcription complex, subunit 7 0.021
Pja2 praja 2, RING-H2 motif containing 0.020
Adss adenylosuccinate synthetase, non muscle 0.020
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Eb1 CG3265 gene product from transcript CG3265-RF 0.075
Act87E Actin 87E 0.062
scra scraps 0.046
Spc105R Spc105-related 0.033
Dat Dopamine N acetyltransferase 0.031
Nmt N-myristoyl transferase 0.028
rho-5 rhomboid-5 0.024
CanA1 Calcineurin A1 0.022
Taf1 TBP-associated factor 1 0.021
Tm2 Tropomyosin 2 0.019
Nek2 CG17256 gene product from transcript CG17256-RA 0.018
CG16885 CG16885 gene product from transcript CG16885-RA 0.017
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.017
alphaTub67C alpha-Tubulin at 67C 0.015
CG5355 CG5355 gene product from transcript CG5355-RA 0.015
Tbp-1 Tat-binding protein-1 0.015
tum tumbleweed 0.015
CanB Calcineurin B 0.014
pim pimples 0.014
Ge-1 CG6181 gene product from transcript CG6181-RA 0.014
CG7203 CG7203 gene product from transcript CG7203-RB 0.014
Prm Paramyosin 0.014
Mlc1 Myosin alkali light chain 1 0.013
Eip63F-1 Ecdysone-induced protein 63F 1 0.013
cpx complexin 0.013
ana3 anastral spindle 3 0.013
Cap-G CG34438 gene product from transcript CG34438-RF 0.013
CG4962 CG4962 gene product from transcript CG4962-RA 0.013
CG31904 CG31904 gene product from transcript CG31904-RD 0.013
CG9302 CG9302 gene product from transcript CG9302-RA 0.012
TpnC73F Troponin C at 73F 0.012
CanA-14F Calcineurin A at 14F 0.012
Mlp84B Muscle LIM protein at 84B 0.012
sra sarah 0.011
cpa capping protein alpha 0.011
Tao-1 CG14217 gene product from transcript CG14217-RF 0.011
per period 0.011
CanB2 Calcineurin B2 0.011
Act5C Actin 5C 0.011
Sply Sphingosine-1-phosphate lyase 0.011
Cpr49Ae Cuticular protein 49Ae 0.010
larp La related protein 0.010
Rab1 Rab-protein 1 0.010
CG5177 CG5177 gene product from transcript CG5177-RA 0.010
sina seven in absentia 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.942
SF3A1 splicing factor 3a, subunit 1, 120kDa 0.766
SRPK2 SRSF protein kinase 2 0.567
KPNB1 karyopherin (importin) beta 1 0.558
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.524
RACGAP1 Rac GTPase activating protein 1 0.520
SF3A2 splicing factor 3a, subunit 2, 66kDa 0.492
RECQL RecQ protein-like (DNA helicase Q1-like) 0.477
TRIM37 tripartite motif containing 37 0.340
CBX5 chromobox homolog 5 0.161
KPNA1 karyopherin alpha 1 (importin alpha 5) 0.116
IPO5 importin 5 0.081
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.077
IRF2 interferon regulatory factor 2 0.069
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.066
KPNA3 karyopherin alpha 3 (importin alpha 4) 0.061
KIF23 kinesin family member 23 0.058
LBR lamin B receptor 0.052
CUL2 cullin 2 0.047
ARF6 ADP-ribosylation factor 6 0.047
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.043
JMJD6 jumonji domain containing 6 0.040
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.040
NKAP NFKB activating protein 0.034
FRA10AC1 fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 0.033
SF3B2 splicing factor 3b, subunit 2, 145kDa 0.032
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 0.032
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.031
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.029
TNPO1 transportin 1 0.029
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.028
SART1 squamous cell carcinoma antigen recognized by T cells 0.026
ECT2 epithelial cell transforming sequence 2 oncogene 0.026
SF1 splicing factor 1 0.025
SMS spermine synthase 0.025
HSPH1 heat shock 105kDa/110kDa protein 1 0.025
TRADD TNFRSF1A-associated via death domain 0.024
CBX1 chromobox homolog 1 0.023
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.022
CENPE centromere protein E, 312kDa 0.021
GPSM2 G-protein signaling modulator 2 0.021
SRPK1 SRSF protein kinase 1 0.020
MESDC2 mesoderm development candidate 2 0.020
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.019
CNOT7 CCR4-NOT transcription complex, subunit 7 0.019
KIF4A kinesin family member 4A 0.019
RBBP7 retinoblastoma binding protein 7 0.019
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.019
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.018
CKAP5 cytoskeleton associated protein 5 0.018
SAP30BP SAP30 binding protein 0.017
EXOC5 exocyst complex component 5 0.017
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.017
TRAF1 TNF receptor-associated factor 1 0.016
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.016
PRPF38A PRP38 pre-mRNA processing factor 38 (yeast) domain containing A 0.016
SUGP1 SURP and G patch domain containing 1 0.016
TRAF2 TNF receptor-associated factor 2 0.015
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.015
WDR26 WD repeat domain 26 0.015
NUP98 nucleoporin 98kDa 0.015
KIF5B kinesin family member 5B 0.014
RAB21 RAB21, member RAS oncogene family 0.014
WDR48 WD repeat domain 48 0.014
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.014
EXOSC9 exosome component 9 0.014
KLHDC5 kelch domain containing 5 0.013
CUL4A cullin 4A 0.013
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.013
NUP153 nucleoporin 153kDa 0.013
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.013
C16orf74 chromosome 16 open reading frame 74 0.012
RBM23 RNA binding motif protein 23 0.012
RBM10 RNA binding motif protein 10 0.012
EZH2 enhancer of zeste homolog 2 (Drosophila) 0.012
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 0.012
DCAF8 DDB1 and CUL4 associated factor 8 0.011
DUT deoxyuridine triphosphatase 0.011
VPRBP Vpr (HIV-1) binding protein 0.011
RAE1 RAE1 RNA export 1 homolog (S. pombe) 0.011
SRRM2 serine/arginine repetitive matrix 2 0.010
USP42 ubiquitin specific peptidase 42 0.010
LUC7L LUC7-like (S. cerevisiae) 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism