The network for 'potassium ion homeostasis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

potassium ion homeostasis

Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell.

Mus musculus
Name Description Probability Func Analog Organism
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.981
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.979
Ank1 ankyrin 1, erythroid 0.898
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.757
Slc12a1 solute carrier family 12, member 1 0.692
Esrrb estrogen related receptor, beta 0.637
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.597
Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit 0.542
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.499
Hand2 heart and neural crest derivatives expressed transcript 2 0.481
Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 0.447
Grid2 glutamate receptor, ionotropic, delta 2 0.386
Pax6 paired box gene 6 0.341
Cdh23 cadherin 23 (otocadherin) 0.323
Srrm4 serine/arginine repetitive matrix 4 0.321
Tmc1 transmembrane channel-like gene family 1 0.302
Cckbr cholecystokinin B receptor 0.301
Calb1 calbindin 1 0.267
Grxcr1 glutaredoxin, cysteine rich 1 0.240
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.223
Lrp2 low density lipoprotein receptor-related protein 2 0.207
Vamp2 vesicle-associated membrane protein 2 0.190
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 0.184
Dab1 disabled homolog 1 (Drosophila) 0.172
Frmd5 FERM domain containing 5 0.163
Chrna9 cholinergic receptor, nicotinic, alpha polypeptide 9 0.162
Osta organic solute transporter alpha 0.153
Ina internexin neuronal intermediate filament protein, alpha 0.153
Slc22a12 solute carrier family 22 (organic anion/cation transporter), member 12 0.152
Phkg1 phosphorylase kinase gamma 1 0.144
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.144
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.143
Kcnk3 potassium channel, subfamily K, member 3 0.142
Wnk2 WNK lysine deficient protein kinase 2 0.140
Clstn1 calsyntenin 1 0.139
Cntn2 contactin 2 0.137
Nos1 nitric oxide synthase 1, neuronal 0.136
Inadl InaD-like (Drosophila) 0.132
Abcc9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.131
Fgf8 fibroblast growth factor 8 0.118
Dao D-amino acid oxidase 0.116
Hrc histidine rich calcium binding protein 0.109
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 0.107
Myl7 myosin, light polypeptide 7, regulatory 0.104
Syt7 synaptotagmin VII 0.104
Gcm2 glial cells missing homolog 2 (Drosophila) 0.103
Pcsk4 proprotein convertase subtilisin/kexin type 4 0.102
Msx1 homeobox, msh-like 1 0.102
Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4) 0.097
Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.097
Homer1 homer homolog 1 (Drosophila) 0.094
Pla2g5 phospholipase A2, group V 0.093
Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) 0.093
Uncx UNC homeobox 0.092
Hsd3b4 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 0.092
Pax3 paired box gene 3 0.090
Nrip3 nuclear receptor interacting protein 3 0.090
Mpp3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.089
Foxi3 forkhead box I3 0.088
Drd2 dopamine receptor D2 0.088
Umod uromodulin 0.087
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.087
Clcnka chloride channel Ka 0.087
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.086
Gjb6 gap junction protein, beta 6 0.085
Neurod2 neurogenic differentiation 2 0.084
Pou3f4 POU domain, class 3, transcription factor 4 0.084
Kcnab3 potassium voltage-gated channel, shaker-related subfamily, beta member 3 0.081
Mapt microtubule-associated protein tau 0.080
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.078
Slc23a3 solute carrier family 23 (nucleobase transporters), member 3 0.077
Rtn2 reticulon 2 (Z-band associated protein) 0.076
Abca4 ATP-binding cassette, sub-family A (ABC1), member 4 0.076
Irx4 Iroquois related homeobox 4 (Drosophila) 0.075
Slc6a1 solute carrier family 6 (neurotransmitter transporter, GABA), member 1 0.074
Slc5a11 solute carrier family 5 (sodium/glucose cotransporter), member 11 0.074
Gsbs G substrate 0.074
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.073
Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 0.072
Slc22a6 solute carrier family 22 (organic anion transporter), member 6 0.071
Hoxb4 homeobox B4 0.070
Bsn bassoon 0.070
Abcc8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.070
Hand1 heart and neural crest derivatives expressed transcript 1 0.070
Cntnap1 contactin associated protein-like 1 0.070
Phex phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) 0.070
Pou4f3 POU domain, class 4, transcription factor 3 0.068
Mfsd4 major facilitator superfamily domain containing 4 0.067
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.067
Foxc1 forkhead box C1 0.067
Odz2 odd Oz/ten-m homolog 2 (Drosophila) 0.065
Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 0.064
Cacnb2 calcium channel, voltage-dependent, beta 2 subunit 0.063
Kcnd2 potassium voltage-gated channel, Shal-related family, member 2 0.063
Hs6st3 heparan sulfate 6-O-sulfotransferase 3 0.063
Pde1c phosphodiesterase 1C 0.063
Nkx6-3 NK6 homeobox 3 0.062
Fgf12 fibroblast growth factor 12 0.062
Tcfap2b transcription factor AP-2 beta 0.059
Sox15 SRY-box containing gene 15 0.058
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
ACTN2 actinin, alpha 2 0.993
MYOZ1 myozenin 1 0.549
KCNB1 potassium voltage-gated channel, Shab-related subfamily, member 1 0.042
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.037
NDRG2 NDRG family member 2 0.022
TTN titin 0.021
KCNA4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.019
NPY neuropeptide Y 0.018
ATP4B ATPase, H+/K+ exchanging, beta polypeptide 0.011
HIPK4 homeodomain interacting protein kinase 4 0.011
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Rattus norvegicus
Name Description Probability Func Analog Organism
Drd1a dopamine receptor D1A 0.094
Mapk3 mitogen activated protein kinase 3 0.081
Ank2 ankyrin 2, neuronal 0.070
Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.056
Arpp21 cAMP-regulated phosphoprotein 21 0.047
Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.035
Chp calcium binding protein p22 0.033
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform 0.032
Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 0.028
Gabrb1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.028
Hs3st2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 0.026
Kcnd3 potassium voltage-gated channel, Shal-related subfamily, member 3 0.026
Crhbp corticotropin releasing hormone binding protein 0.025
Opcml opioid binding protein/cell adhesion molecule-like 0.024
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.024
Slc12a1 solute carrier family 12 (sodium/potassium/chloride transporters), member 1 0.023
Nrxn3 neurexin 3 0.023
Cntn3 contactin 3 (plasmacytoma associated) 0.023
Kcnk3 potassium channel, subfamily K, member 3 0.022
Glra3 glycine receptor, alpha 3 0.021
Mas1 MAS1 oncogene 0.020
Coro2b coronin, actin binding protein, 2B 0.020
Myt1l myelin transcription factor 1-like 0.019
Cyp2b21 cytochrome P450, family 2, subfamily b, polypeptide 21 0.019
Vip vasoactive intestinal peptide 0.019
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.017
Psbpc2 prostatic steroid-binding protein C2 0.017
Scn4b sodium channel, voltage-gated, type IV, beta 0.017
Rph3a rabphilin 3A 0.017
Brunol4 bruno-like 4, RNA binding protein (Drosophila) 0.017
Dgkb diacylglycerol kinase, beta 0.016
Fgf14 fibroblast growth factor 14 0.016
Map1a microtubule-associated protein 1A 0.016
Gnao1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.016
Chrm1 cholinergic receptor, muscarinic 1 0.016
Rimbp2 RIMS binding protein 2 0.015
Chst10 carbohydrate sulfotransferase 10 0.015
Cs citrate synthase 0.015
Epha5 EphA5 0.015
Dbc1 deleted in bladder cancer 1 (human) 0.015
Tmem90b transmembrane protein 90B 0.015
Gabra1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.015
Crh corticotropin releasing hormone 0.015
Arhgef9 Cdc42 guanine nucleotide exchange factor (GEF) 9 0.014
Gpr61 G protein-coupled receptor 61 0.014
Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.014
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.014
Sorcs3 sortilin-related VPS10 domain containing receptor 3 0.014
Slc38a1 solute carrier family 38, member 1 0.014
RGD1310269 hypothetical LOC314472 0.014
Snap91 synaptosomal-associated protein 91 0.014
Necab1 N-terminal EF-hand calcium binding protein 1 0.014
Faim2 Fas apoptotic inhibitory molecule 2 0.014
Elavl4 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) 0.014
Ddn dendrin 0.014
Mfrp membrane frizzled-related protein 0.014
S100b S100 calcium binding protein B 0.013
Tnmd tenomodulin 0.013
Cadps Ca++-dependent secretion activator 0.013
Cplx1 complexin 1 0.013
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.013
Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 0.013
Fgf13 fibroblast growth factor 13 0.013
Slc28a3 solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 0.013
Nrn1 neuritin 1 0.013
LOC685244 similar to IQ motif and Sec7 domain 2 0.013
Rims1 regulating synaptic membrane exocytosis 1 0.013
Gria1 glutamate receptor, ionotropic, AMPA 1 0.013
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 0.013
Grm4 glutamate receptor, metabotropic 4 0.013
Acsl6 acyl-CoA synthetase long-chain family member 6 0.012
Tmod2 tropomodulin 2 0.012
Ryr2 ryanodine receptor 2, cardiac 0.012
Galntl1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1 0.012
Gria4 glutamate receptor, ionotrophic, AMPA 4 0.012
Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.012
RGD1560559 similar to RIKEN cDNA 2310042E22 0.012
Nxph1 neurexophilin 1 0.012
Rab1b RAB1B, member RAS oncogene family 0.012
Kcnh1 potassium voltage-gated channel, subfamily H (eag-related), member 1 0.012
Cntnap1 contactin associated protein 1 0.012
Svs5 seminal vesicle secretory protein 5 0.012
Rho rhodopsin 0.012
Camk2b calcium/calmodulin-dependent protein kinase II beta 0.012
Ifng interferon gamma 0.012
Epb41l1 erythrocyte membrane protein band 4.1-like 1 0.012
Syt6 synaptotagmin VI 0.011
Adrb1 adrenergic, beta-1-, receptor 0.011
Sparcl1 SPARC-like 1 (hevin) 0.011
Slc24a3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.011
Aard alanine and arginine rich domain containing protein 0.011
Prl7d1 prolactin family 7, subfamily d, member 1 0.011
Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 0.011
Cpne9 copine family member IX 0.011
Nfasc neurofascin 0.011
Kcnip2 Kv channel-interacting protein 2 0.011
Sema4f sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 0.011
Begain brain-enriched guanylate kinase-associated 0.011
Olr416 olfactory receptor 416 0.011
Syt4 synaptotagmin IV 0.011
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
TRK1 Trk1p 0.837
NHA1 Nha1p 0.571
TRK2 Trk2p 0.398
MIG2 Mig2p 0.299
FPS1 Fps1p 0.153
TOK1 Tok1p 0.149
ROX1 Rox1p 0.113
YKR075C hypothetical protein 0.107
YPL014W hypothetical protein 0.095
GAT2 Gat2p 0.085
NRG1 Nrg1p 0.072
YKL187C hypothetical protein 0.066
MIG3 Mig3p 0.057
VPS8 Vps8p 0.055
HAL5 Hal5p 0.049
GIS4 Gis4p 0.049
TRA1 Tra1p 0.048
YBR235W hypothetical protein 0.047
VID24 Vid24p 0.045
MIG1 Mig1p 0.040
MRM1 Mrm1p 0.036
YML081W hypothetical protein 0.036
RGS2 Rgs2p 0.035
RSC9 Rsc9p 0.032
SWI1 Swi1p 0.032
HSF1 Hsf1p 0.032
HXT3 Hxt3p 0.030
YPR157W hypothetical protein 0.028
MDM38 Mdm38p 0.025
CAB4 Cab4p 0.024
SOK2 Sok2p 0.023
TYE7 Tye7p 0.023
HAL9 Hal9p 0.021
CSR2 Csr2p 0.020
LYS5 Lys5p 0.020
CAT8 Cat8p 0.018
YER064C hypothetical protein 0.018
TOR2 Tor2p 0.017
TOS8 Tos8p 0.017
AQR1 Aqr1p 0.017
AGP2 Agp2p 0.016
IRC8 Irc8p 0.015
MRP4 Mrp4p 0.015
RDS2 Rds2p 0.015
YIR035C hypothetical protein 0.015
SNF3 Snf3p 0.015
PHM8 Phm8p 0.014
MOB1 Mob1p 0.014
YNL234W hypothetical protein 0.013
YLR264C-A hypothetical protein 0.013
SRD1 Srd1p 0.013
ATF1 Atf1p 0.013
SMP1 Smp1p 0.012
TBS1 Tbs1p 0.012
ICY1 Icy1p 0.012
POG1 Pog1p 0.012
HOR2 Hor2p 0.012
PMD1 Pmd1p 0.012
SKS1 Sks1p 0.012
PCL2 Pcl2p 0.012
FIR1 Fir1p 0.012
FMP48 Fmp48p 0.012
HST3 Hst3p 0.011
LEU2 Leu2p 0.011
BSC2 Bsc2p 0.011
CHA1 Cha1p 0.011
MGA2 Mga2p 0.011
RLM1 Rlm1p 0.011
CUP1-1 Cup1-1p 0.011
DAL81 Dal81p 0.011
FPK1 Fpk1p 0.011
MDM32 Mdm32p 0.011
MER1 Mer1p 0.010
GCN2 Gcn2p 0.010
PUT1 Put1p 0.010