The network for 'hatching' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

hatching

The emergence of an immature organism from a protective structure.

Name Description Probability Func Analog Organism
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.505
pcsk1 proprotein convertase subtilisin/kexin type 1 0.324
edn1 endothelin 1 0.270
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.254
ihha Indian hedgehog homolog a 0.218
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.212
calm1a calmodulin 1a 0.198
plcb3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.170
fras1 Fraser syndrome 1 0.161
shbg sex hormone binding globulin 0.155
tagln2 transgelin 2 0.148
col10a1 collagen, type X, alpha 1 0.132
LOC100538002 DNA-directed RNA polymerase II subunit RPB2-like 0.125
ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 0.122
csnk1a1 casein kinase 1, alpha 1 0.121
krt4 keratin 4 0.120
si:dkey-72l14.8 si:dkey-72l14.8 0.118
anxa2a annexin A2a 0.114
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.114
pcsk7 proprotein convertase subtilisin/kexin type 7 0.113
dpysl5a dihydropyrimidinase-like 5a 0.112
col1a2 collagen, type I, alpha 2 0.110
ctsl1b cathepsin L, 1 b 0.107
actr1 ARP1 actin-related protein 1, centractin (yeast) 0.107
slc4a1a solute carrier family 4, anion exchanger, member 1a 0.097
si:dkeyp-66d7.2 si:dkeyp-66d7.2 0.095
hsp90a.1 heat shock protein 90-alpha 1 0.091
f7 coagulation factor VII 0.089
ap2b1 adaptor-related protein complex 2, beta 1 subunit 0.089
gpc4 glypican 4 0.087
pola2 polymerase (DNA directed), alpha 2 0.085
vps35 vacuolar protein sorting 35 (yeast) 0.085
dbh dopamine beta hydroxylase 0.085
disp1 dispatched homolog 1 (Drosophila) 0.085
hk1 hexokinase 1 0.081
ywhai tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide 0.080
sec24d SEC24 family, member D (S. cerevisiae) 0.079
ywhaqa tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a 0.078
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.072
lsm7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.071
perp PERP, TP53 apoptosis effector 0.071
uba1 ubiquitin-like modifier activating enzyme 1 0.071
rapsn receptor-associated protein of the synapse, 43kD 0.070
szl sizzled 0.070
ywhaba tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a 0.070
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.069
rerea arginine-glutamic acid dipeptide (RE) repeats a 0.067
cltcb clathrin, heavy polypeptide b (Hc) 0.063
brd2a bromodomain-containing 2a 0.063
psmc1b proteasome (prosome, macropain) 26S subunit, ATPase, 1b 0.062
bactin1 bactin1 0.061
ptch1 patched 1 0.061
uchl1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.060
furinb furin (paired basic amino acid cleaving enzyme) b 0.060
chd chordin 0.059
tuba8l4 tubulin, alpha 8 like 4 0.057
copa coatomer protein complex, subunit alpha 0.056
uba3 ubiquitin-like modifier activating enzyme 3 0.055
psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.055
psma4 proteasome (prosome, macropain) subunit, alpha type, 4 0.053
usp5 ubiquitin specific protease 5 0.053
cpa1 carboxypeptidase A1 (pancreatic) 0.052
ets1a v-ets erythroblastosis virus E26 oncogene homolog 1a 0.052
u2af2b U2 small nuclear RNA auxiliary factor 2b 0.051
pcsk5a proprotein convertase subtilisin/kexin type 5a 0.050
syne1a spectrin repeat containing, nuclear envelope 1a 0.050
polr2d polymerase (RNA) II (DNA directed) polypeptide D 0.050
frem1a Fras1 related extracellular matrix 1a 0.050
fam20b family with sequence similarity 20, member B (H. sapiens) 0.049
bactin2 bactin2 0.049
rictor RPTOR independent companion of MTOR, complex 2 0.048
cpb1 carboxypeptidase B1 (tissue) 0.048
flncb filamin C, gamma b (actin binding protein 280) 0.048
uxs1 UDP-glucuronic acid decarboxylase 1 0.048
cel.1 carboxyl ester lipase, tandem duplicate 1 0.047
elovl1b elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1b 0.047
glmna glomulin, FKBP associated protein a 0.047
slc35b2 solute carrier family 35, member B2 0.047
chia.2 chitinase, acidic.2 0.046
xylt1 xylosyltransferase 1 0.046
nup107 nucleoporin 107 0.045
tfap2c transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.045
acsbg2 acyl-CoA synthetase bubblegum family member 2 0.045
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.045
spns2 spinster homolog 2 (Drosophila) 0.044
tlr21 toll-like receptor 21 0.044
srd5a2a steroid-5-alpha-reductase, alpha polypeptide 2a 0.043
atrx alpha thalassemia/mental retardation syndrome X-linked homolog (human) 0.043
ccm2 cerebral cavernous malformation 2 0.042
hpca hippocalcin 0.042
col1a1a collagen, type I, alpha 1a 0.042
nadka NAD kinase a 0.042
cdc45 CDC45 cell division cycle 45 homolog (S. cerevisiae) 0.042
sptb spectrin, beta, erythrocytic 0.042
smek2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) 0.041
pkm2a pyruvate kinase, muscle, a 0.040
dpysl3 dihydropyrimidinase-like 3 0.040
cyp2ad2 cytochrome P450, family 2, subfamily AD, polypeptide 2 0.040
capza1b capping protein (actin filament) muscle Z-line, alpha 1b 0.040
mhc2dcb major histocompatibility complex class II DCB gene 0.040
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
ace-1 Protein ACE-1 0.128
puf-7 Protein PUF-7 0.116
lag-2 Protein LAG-2 0.097
T11G6.8 Protein T11G6.8 0.082
hlh-28 Protein HLH-28 0.080
lin-12 Protein LIN-12 0.079
oma-1 Protein OMA-1 0.076
ace-4 Protein ACE-4 0.073
ace-2 Protein ACE-2 0.065
F33D11.10 Protein F33D11.10 0.063
pal-1 Protein PAL-1 0.063
mex-6 Protein MEX-6 0.062
hlh-29 Protein HLH-29 0.057
fat-2 Protein FAT-2 0.056
unc-54 Protein UNC-54 0.053
orc-2 Protein ORC-2 0.052
rad-51 Protein RAD-51 0.045
T21C9.4 Protein T21C9.4 0.044
lst-1 Protein LST-1 0.043
mes-3 Protein MES-3 0.042
pry-1 Protein PRY-1 0.042
T12E12.3 Protein T12E12.3 0.040
ppfr-4 Protein PPFR-4 0.039
zip-7 Protein ZIP-7 0.039
arp-1 Protein ARP-1 0.038
rmd-1 Protein RMD-1 0.035
dnc-3 Protein DNC-3 0.034
C02F5.6 Protein C02F5.6 0.034
fkh-9 Protein FKH-9 0.033
ace-3 Protein ACE-3 0.033
lrr-1 Protein LRR-1 0.032
W03F8.4 Protein W03F8.4 0.032
pod-1 Protein POD-1 0.032
ssl-1 Protein SSL-1 0.031
C04F12.5 Protein C04F12.5 0.031
snrp-200 Protein SNRP-200 0.031
pph-4.1 Protein PPH-4.1 0.030
sma-3 Protein SMA-3 0.030
let-60 Protein LET-60 0.029
C35D10.7 Protein C35D10.7 0.028
sun-1 Protein SUN-1 0.028
teg-4 Protein TEG-4 0.028
T28D9.3 Protein T28D9.3 0.028
mex-5 Protein MEX-5 0.027
bath-42 Protein BATH-42 0.027
CELE_F43D2.1 Protein F43D2.1 0.026
lec-8 Protein LEC-8 0.026
cpg-2 Protein CPG-2 0.026
vab-3 Protein VAB-3 0.025
trcs-1 Protein TRCS-1 0.025
CELE_H28G03.1 Protein H28G03.1 0.025
gln-5 Protein GLN-5 0.025
amph-1 Protein AMPH-1 0.025
pph-6 Protein PPH-6 0.024
dnj-12 Protein DNJ-12 0.024
npr-1 Protein NPR-1 0.024
pqn-44 Protein PQN-44 0.024
cdc-25.1 Protein CDC-25.1 0.024
nos-2 Protein NOS-2 0.023
C35A5.8 Protein C35A5.8 0.023
tag-333 Protein TAG-333 0.023
ZK973.9 Protein ZK973.9 0.023
T01C3.3 Protein T01C3.3 0.023
ztf-4 Protein ZTF-4 0.023
htp-1 Protein HTP-1 0.023
sur-6 Protein SUR-6 0.023
F19B6.1 Protein F19B6.1 0.023
gip-1 Protein GIP-1 0.022
ZK1055.7 Protein ZK1055.7 0.022
meg-1 Protein MEG-1 0.022
CELE_M04B2.2 Protein M04B2.2 0.022
puf-5 Protein PUF-5 0.022
cyb-2.1 Protein CYB-2.1 0.022
sos-1 Protein SOS-1 0.022
lron-7 Protein LRON-7 0.021
rars-1 Protein RARS-1 0.021
puf-3 Protein PUF-3 0.021
lin-39 Protein LIN-39 0.021
ppfr-1 Protein PPFR-1 0.021
let-721 Protein LET-721 0.021
mlh-1 Protein MLH-1 0.020
mab-5 Protein MAB-5 0.020
CELE_C01G6.5 Protein C01G6.5 0.020
mel-26 Protein MEL-26 0.020
D1081.7 Protein D1081.7 0.020
npp-18 Protein NPP-18 0.020
mdt-15 Protein MDT-15 0.020
rpa-1 Protein RPA-1 0.020
clec-88 Protein CLEC-88 0.020
pie-1 Protein PIE-1 0.020
pdhk-2 Protein PDHK-2 0.020
F48E8.2 Protein F48E8.2 0.020
akt-2 Protein AKT-2 0.019
unc-60 Protein UNC-60 0.019
CELE_Y111B2A.3 Protein Y111B2A.3 0.019
CELE_ZK337.2 Protein ZK337.2 0.019
lsl-1 Protein LSL-1 0.019
C01G8.1 Protein C01G8.1 0.019
bam-2 Protein BAM-2 0.019
hda-2 Protein HDA-2 0.019
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Drosophila melanogaster
Name Description Probability Func Analog Organism
MED28 Mediator complex subunit 28 0.035
CG10418 CG10418 gene product from transcript CG10418-RA 0.028
Gug Grunge 0.022
SmF Small ribonucleoprotein particle protein SmF 0.021
CG6610 CG6610 gene product from transcript CG6610-RA 0.019
CycC Cyclin C 0.019
VAChT CG32848 gene product from transcript CG32848-RA 0.018
wac wee Augmin 0.017
Nedd8 CG10679 gene product from transcript CG10679-RA 0.017
ogre optic ganglion reduced 0.017
Ten-m Tenascin major 0.016
pan pangolin 0.016
mirr mirror 0.015
Ard1 Arrest defective 1 0.014
Npc1a Niemann-Pick type C-1a 0.014
grh grainy head 0.014
Pka-C1 cAMP-dependent protein kinase 1 0.014
Cks30A Cyclin-dependent kinase subunit 30A 0.014
Eip75B Ecdysone-induced protein 75B 0.014
l(2)gl lethal (2) giant larvae 0.013
tsu tsunagi 0.013
Prx6005 Peroxiredoxin 6005 0.013
l(2)37Cg lethal (2) 37Cg 0.012
CdsA CDP diglyceride synthetase 0.012
Sgt1 CG9617 gene product from transcript CG9617-RA 0.012
TFAM mitochondrial transcription factor A 0.012
CG9548 CG9548 gene product from transcript CG9548-RA 0.012
trol terribly reduced optic lobes 0.012
lsn larsen 0.012
CG5568 CG5568 gene product from transcript CG5568-RA 0.011
CG14270 CG14270 gene product from transcript CG14270-RA 0.011
hay haywire 0.011
mRpL11 mitochondrial ribosomal protein L11 0.011
mus209 mutagen-sensitive 209 0.011
sw short wing 0.011
crn crooked neck 0.011
LSm3 CG31184 gene product from transcript CG31184-RA 0.011
RpII33 RNA polymerase II 33kD subunit 0.010
baf barrier to autointegration factor 0.010
Cypl Cyclophilin-like 0.010
CG6937 CG6937 gene product from transcript CG6937-RA 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.949
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.936
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.691
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.611
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.534
Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform 0.530
Arid1b AT rich interactive domain 1B (SWI-like) 0.527
Rpgrip1l Rpgrip1-like 0.348
Lrrk2 leucine-rich repeat kinase 2 0.296
Usp18 ubiquitin specific peptidase 18 0.225
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.208
Trim25 tripartite motif-containing 25 0.179
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.179
Oasl2 2'-5' oligoadenylate synthetase-like 2 0.123
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.119
Vhl von Hippel-Lindau tumor suppressor 0.107
Smarcc2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.102
Axin1 axin 1 0.100
Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.089
Serp1 stress-associated endoplasmic reticulum protein 1 0.081
Mcm2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) 0.077
Ifi35 interferon-induced protein 35 0.071
H47 histocompatibility 47 0.063
Fasn fatty acid synthase 0.063
Timeless timeless homolog (Drosophila) 0.060
Nedd4l neural precursor cell expressed, developmentally down-regulated gene 4-like 0.056
Fgfr2 fibroblast growth factor receptor 2 0.056
Apc adenomatosis polyposis coli 0.055
Ifit1 interferon-induced protein with tetratricopeptide repeats 1 0.054
Pthlh parathyroid hormone-like peptide 0.052
Smarcd1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 0.048
Tceb3 transcription elongation factor B (SIII), polypeptide 3 0.047
Actn4 actinin alpha 4 0.045
Pgd phosphogluconate dehydrogenase 0.045
Irgm1 immunity-related GTPase family M member 1 0.041
Txndc17 thioredoxin domain containing 17 0.040
Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.039
Foxo1 forkhead box O1 0.035
H2afx H2A histone family, member X 0.034
Brca2 breast cancer 2 0.032
Gbp7 guanylate binding protein 7 0.031
Mark2 MAP/microtubule affinity-regulating kinase 2 0.031
Lrp6 low density lipoprotein receptor-related protein 6 0.031
Irf6 interferon regulatory factor 6 0.031
Vat1 vesicle amine transport protein 1 homolog (T californica) 0.030
Eno1 enolase 1, alpha non-neuron 0.029
Smpd3 sphingomyelin phosphodiesterase 3, neutral 0.029
Smarcd3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 0.029
Psmd11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.029
Prmt5 protein arginine N-methyltransferase 5 0.028
Pgrmc1 progesterone receptor membrane component 1 0.028
Xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1 0.028
Nefm neurofilament, medium polypeptide 0.028
Erap1 endoplasmic reticulum aminopeptidase 1 0.028
Arid1a AT rich interactive domain 1A (SWI-like) 0.027
Brca1 breast cancer 1 0.027
Zbtb45 zinc finger and BTB domain containing 45 0.027
Rsad2 radical S-adenosyl methionine domain containing 2 0.027
Wdr19 WD repeat domain 19 0.026
Ints9 integrator complex subunit 9 0.026
Mavs mitochondrial antiviral signaling protein 0.026
Trp53 transformation related protein 53 0.026
Whsc1 Wolf-Hirschhorn syndrome candidate 1 (human) 0.025
Iqcb1 IQ calmodulin-binding motif containing 1 0.025
Mecp2 methyl CpG binding protein 2 0.025
Stat1 signal transducer and activator of transcription 1 0.025
Rtp4 receptor transporter protein 4 0.025
Zc3h12d zinc finger CCCH type containing 12D 0.024
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.024
Pole polymerase (DNA directed), epsilon 0.024
Parp12 poly (ADP-ribose) polymerase family, member 12 0.024
Tkt transketolase 0.024
Smarce1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.024
1500010J02Rik RIKEN cDNA 1500010J02 gene 0.024
Eftud2 elongation factor Tu GTP binding domain containing 2 0.023
Pold2 polymerase (DNA directed), delta 2, regulatory subunit 0.023
Gtf2h4 general transcription factor II H, polypeptide 4 0.023
Nphp1 nephronophthisis 1 (juvenile) homolog (human) 0.023
Gns glucosamine (N-acetyl)-6-sulfatase 0.023
Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 0.023
Mgat2 mannoside acetylglucosaminyltransferase 2 0.023
Irgm2 immunity-related GTPase family M member 2 0.022
Epn1 epsin 1 0.022
Sf3a2 splicing factor 3a, subunit 2 0.022
Zeb1 zinc finger E-box binding homeobox 1 0.022
Spnb2 spectrin beta 2 0.022
Rnf135 ring finger protein 135 0.022
Arl1 ADP-ribosylation factor-like 1 0.022
Ifi44 interferon-induced protein 44 0.022
Ppp2r4 protein phosphatase 2A, regulatory subunit B (PR 53) 0.022
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.022
Mnd1 meiotic nuclear divisions 1 homolog (S. cerevisiae) 0.021
Rcc2 regulator of chromosome condensation 2 0.021
Irf7 interferon regulatory factor 7 0.021
Elk4 ELK4, member of ETS oncogene family 0.021
Tcirg1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 0.021
Arpc4 actin related protein 2/3 complex, subunit 4 0.021
Cadps2 Ca2+-dependent activator protein for secretion 2 0.021
Esrrb estrogen related receptor, beta 0.021
Mapt microtubule-associated protein tau 0.020
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism