The network for 'trabecula morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

trabecula morphogenesis

The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.

Danio rerio
Name Description Probability Func Analog Organism
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.974
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.738
tbx1 T-box 1 0.333
notch1b notch homolog 1b 0.223
nrg1 neuregulin 1 0.206
aplnra apelin receptor a 0.154
rest RE1-silencing transcription factor 0.137
kdrl kinase insert domain receptor like 0.126
col12a1 collagen, type XII, alpha 1 0.121
tnnt2a troponin T2a, cardiac 0.114
fbn2b fibrillin 2b 0.110
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.097
srl sarcalumenin 0.090
wnt11r wingless-type MMTV integration site family, member 11, related 0.079
flt4 fms-related tyrosine kinase 4 0.077
card14 caspase recruitment domain family, member 14 0.073
notch3 notch homolog 3 0.071
fn1 fibronectin 1 0.065
cldn5b claudin 5b 0.059
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.056
tie1 endothelium-specific receptor tyrosine kinase 1 0.055
wnt3 wingless-type MMTV integration site family, member 3 0.055
dlc deltaC 0.054
nrarpa notch-regulated ankyrin repeat protein a 0.054
ptprja protein tyrosine phosphatase, receptor type, J a 0.052
erbb3a v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a 0.050
zgc:91930 zgc:91930 0.049
dzip1 DAZ interacting protein 1 0.048
wnt10a wingless-type MMTV integration site family, member 10a 0.047
nfatc1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.044
klf4a Kruppel-like transcription factor 4a 0.043
bnc2 basonuclin 2 0.042
itga3b integrin, alpha 3b 0.040
etv2 ets variant gene 2 0.040
wnt8a wingless-type MMTV integration site family, member 8a 0.040
mcoln1 mucolipin 1 0.040
si:dkeyp-7c9.1 si:dkeyp-7c9.1 0.039
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.039
col19a1 collagen, type XIX, alpha 1 0.037
oep one-eyed pinhead 0.036
acta2 actin, alpha 2, smooth muscle, aorta 0.035
vsg1 vessel-specific 1 0.035
tll1 tolloid-like 1 0.034
sox11b SRY-box containing gene 11b 0.034
cdh5 cadherin 5 0.034
stac3 SH3 and cysteine rich domain 3 0.032
appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.032
dkk3 dickkopf homolog 3 (Xenopus laevis) 0.032
spna2 spectrin alpha 2 0.032
sox10 SRY-box containing gene 10 0.032
arl4ab ADP-ribosylation factor-like 4ab 0.032
col5a1 procollagen, type V, alpha 1 0.032
acta1b actin, alpha 1b, skeletal muscle 0.031
kdr kinase insert domain receptor (a type III receptor tyrosine kinase) 0.031
col4a5 collagen, type IV, alpha 5 (Alport syndrome) 0.031
wnt9b wingless-type MMTV integration site family, member 9B 0.031
myo10l1 myosin X-like 1 0.030
igf2a insulin-like growth factor 2a 0.030
gpr182 G protein-coupled receptor 182 0.030
actc1a actin, alpha, cardiac muscle 1a 0.029
snapc1b small nuclear RNA activating complex, polypeptide 1b 0.029
si:dkey-151c10.1 si:dkey-151c10.1 0.029
frem3 Fras1 related extracellular matrix 3 0.028
rel v-rel reticuloendotheliosis viral oncogene homolog 0.028
comta catechol-O-methyltransferase a 0.028
gata2a GATA-binding protein 2a 0.028
arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 0.028
tbpl2 TATA box binding protein like 2 0.027
nme4 non-metastatic cells 4, protein expressed in 0.027
fzd7b frizzled homolog 7b 0.027
sgcd sarcoglycan, delta (dystrophin-associated glycoprotein) 0.027
eef1g eukaryotic translation elongation factor 1 gamma 0.027
slc8a1a solute carrier family 8 (sodium/calcium exchanger), member 1a 0.026
hspa12b heat shock protein 12B 0.026
LOC100000687 signal peptide, CUB and EGF-like domain-containing protein 3-like 0.026
bmp2a bone morphogenetic protein 2a 0.026
sepp1a selenoprotein P, plasma, 1a 0.026
egr2b early growth response 2b 0.026
pno1 partner of NOB1 homolog (S. cerevisiae) 0.026
kbp kif1-binding protein 0.025
timp2a tissue inhibitor of metalloproteinase 2a 0.025
desma desmin a 0.025
camsap1l1 calmodulin regulated spectrin-associated protein 1-like 1 0.025
fabp11a fatty acid binding protein 11a 0.025
arhgef7b Rho guanine nucleotide exchange factor (GEF) 7b 0.025
dlb deltaB 0.024
ptprma protein tyrosine phosphatase, receptor type, M, a 0.024
angptl2 angiopoietin-like 2 0.024
fancd2 Fanconi anemia, complementation group D2 0.024
si:ch211-173o4.2 si:ch211-173o4.2 0.024
ptk6a PTK6 protein tyrosine kinase 6a 0.024
zbtb4 zinc finger and BTB domain containing 4 0.024
LOC555739 serine/threonine-protein kinase LMTK1-like 0.024
scn4ab sodium channel, voltage-gated, type IV, alpha, b 0.024
axin1 axin 1 0.024
prdm5 PR domain containing 5 0.023
si:ch73-60e21.1 si:ch73-60e21.1 0.023
klf2a Kruppel-like factor 2a 0.023
zgc:136894 zgc:136894 0.023
rbm24b RNA binding motif protein 24b 0.023
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.914
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.644
RND1 Rho family GTPase 1 0.578
TBX5 T-box 5 0.565
JAG1 jagged 1 0.550
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.465
NOTCH1 notch 1 0.459
ANGPT2 angiopoietin 2 0.450
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.430
MKL1 megakaryoblastic leukemia (translocation) 1 0.345
TGFB1 transforming growth factor, beta 1 0.319
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.289
TIMP2 TIMP metallopeptidase inhibitor 2 0.253
NCOR2 nuclear receptor corepressor 2 0.237
VCP valosin containing protein 0.229
NOTCH3 notch 3 0.216
ACVR1B activin A receptor, type IB 0.193
TTR transthyretin 0.182
XIAP X-linked inhibitor of apoptosis 0.170
MAML1 mastermind-like 1 (Drosophila) 0.162
GRB7 growth factor receptor-bound protein 7 0.160
ATXN1L ataxin 1-like 0.149
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.145
EGLN3 egl nine homolog 3 (C. elegans) 0.126
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.102
TGFBR1 transforming growth factor, beta receptor 1 0.100
A2M alpha-2-macroglobulin 0.095
EPAS1 endothelial PAS domain protein 1 0.093
THBS1 thrombospondin 1 0.082
MYOCD myocardin 0.081
SMAD9 SMAD family member 9 0.078
FUNDC2 FUN14 domain containing 2 0.070
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.070
GATA4 GATA binding protein 4 0.068
DLL1 delta-like 1 (Drosophila) 0.066
VAV3 vav 3 guanine nucleotide exchange factor 0.066
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.065
MSX1 msh homeobox 1 0.064
TP53BP1 tumor protein p53 binding protein 1 0.062
NCOR1 nuclear receptor corepressor 1 0.061
SP1 Sp1 transcription factor 0.058
EIF3E eukaryotic translation initiation factor 3, subunit E 0.058
COL1A2 collagen, type I, alpha 2 0.057
IGFBP3 insulin-like growth factor binding protein 3 0.057
NSFL1C NSFL1 (p97) cofactor (p47) 0.055
BTF3 basic transcription factor 3 0.052
MYOD1 myogenic differentiation 1 0.051
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.050
TAL1 T-cell acute lymphocytic leukemia 1 0.050
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.050
PBRM1 polybromo 1 0.049
CFL1 cofilin 1 (non-muscle) 0.049
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.048
GTF2I general transcription factor IIi 0.048
FBN1 fibrillin 1 0.046
ENG endoglin 0.045
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.044
TAGLN2 transgelin 2 0.043
THBS2 thrombospondin 2 0.043
AR androgen receptor 0.043
JAG2 jagged 2 0.043
MYOG myogenin (myogenic factor 4) 0.042
TGFB3 transforming growth factor, beta 3 0.040
ITGA7 integrin, alpha 7 0.040
FOXO1 forkhead box O1 0.040
COL3A1 collagen, type III, alpha 1 0.039
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.039
RPL36A ribosomal protein L36a 0.039
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 0.039
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.039
MED10 mediator complex subunit 10 0.038
ACTG1 actin, gamma 1 0.038
SNW1 SNW domain containing 1 0.038
COL4A1 collagen, type IV, alpha 1 0.038
ARNT aryl hydrocarbon receptor nuclear translocator 0.038
VHL von Hippel-Lindau tumor suppressor 0.037
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.036
FN1 fibronectin 1 0.035
DDR2 discoidin domain receptor tyrosine kinase 2 0.034
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.034
NOTCH2 notch 2 0.033
UBXN2A UBX domain protein 2A 0.033
ATXN3 ataxin 3 0.033
FSTL1 follistatin-like 1 0.032
EIF3H eukaryotic translation initiation factor 3, subunit H 0.032
PTPRC protein tyrosine phosphatase, receptor type, C 0.031
MKL2 MKL/myocardin-like 2 0.031
FHL3 four and a half LIM domains 3 0.031
EIF4B eukaryotic translation initiation factor 4B 0.031
PTK6 PTK6 protein tyrosine kinase 6 0.031
ZNF830 zinc finger protein 830 0.031
AMFR autocrine motility factor receptor 0.030
TNS3 tensin 3 0.030
NID2 nidogen 2 (osteonidogen) 0.030
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.030
PPARA peroxisome proliferator-activated receptor alpha 0.029
GOLM1 golgi membrane protein 1 0.029
CDK19 cyclin-dependent kinase 19 0.028
VWF von Willebrand factor 0.028
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.028
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Mus musculus
Name Description Probability Func Analog Organism
Dll1 delta-like 1 (Drosophila) 0.869
Prrx1 paired related homeobox 1 0.790
Hand1 heart and neural crest derivatives expressed transcript 1 0.774
Notch1 Notch gene homolog 1 (Drosophila) 0.773
Hand2 heart and neural crest derivatives expressed transcript 2 0.737
Lox lysyl oxidase 0.713
Fgf8 fibroblast growth factor 8 0.603
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.585
Fgfr1 fibroblast growth factor receptor 1 0.579
Nfatc4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 0.480
Col5a2 collagen, type V, alpha 2 0.410
Kdr kinase insert domain protein receptor 0.394
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.393
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.382
Gdnf glial cell line derived neurotrophic factor 0.376
Shh sonic hedgehog 0.372
Psen1 presenilin 1 0.359
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.359
Foxc2 forkhead box C2 0.351
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.340
Ror1 receptor tyrosine kinase-like orphan receptor 1 0.330
Col11a1 collagen, type XI, alpha 1 0.323
Efnb2 ephrin B2 0.323
Sox10 SRY-box containing gene 10 0.322
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.315
Eya1 eyes absent 1 homolog (Drosophila) 0.308
Col3a1 collagen, type III, alpha 1 0.294
Col6a2 collagen, type VI, alpha 2 0.286
Plat plasminogen activator, tissue 0.272
Col5a1 collagen, type V, alpha 1 0.260
Nos3 nitric oxide synthase 3, endothelial cell 0.253
Smad3 MAD homolog 3 (Drosophila) 0.249
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.237
Dll4 delta-like 4 (Drosophila) 0.234
Msx1 homeobox, msh-like 1 0.231
Foxc1 forkhead box C1 0.227
Prrx2 paired related homeobox 2 0.221
Ednra endothelin receptor type A 0.219
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.218
Epas1 endothelial PAS domain protein 1 0.217
Dmd dystrophin, muscular dystrophy 0.207
Dlx5 distal-less homeobox 5 0.204
Col2a1 collagen, type II, alpha 1 0.202
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.198
Alx4 aristaless-like homeobox 4 0.198
Lama5 laminin, alpha 5 0.196
Nfatc2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.191
Pax3 paired box gene 3 0.191
Col1a2 collagen, type I, alpha 2 0.191
Ret ret proto-oncogene 0.185
Alx3 aristaless-like homeobox 3 0.183
Sfrp1 secreted frizzled-related protein 1 0.181
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.168
Nrp1 neuropilin 1 0.165
Ednrb endothelin receptor type B 0.163
Bmp7 bone morphogenetic protein 7 0.163
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.161
Fzd1 frizzled homolog 1 (Drosophila) 0.159
Col15a1 collagen, type XV, alpha 1 0.157
Snai1 snail homolog 1 (Drosophila) 0.156
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.156
Chd7 chromodomain helicase DNA binding protein 7 0.154
Tgfb2 transforming growth factor, beta 2 0.151
Has1 hyaluronan synthase1 0.146
Has2 hyaluronan synthase 2 0.143
Hoxa11 homeobox A11 0.138
Dlx2 distal-less homeobox 2 0.138
Eln elastin 0.138
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.136
Col12a1 collagen, type XII, alpha 1 0.133
Cilp2 cartilage intermediate layer protein 2 0.132
Wnt3a wingless-related MMTV integration site 3A 0.131
Fstl1 follistatin-like 1 0.131
Gpc3 glypican 3 0.131
Gata6 GATA binding protein 6 0.131
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.130
Col6a1 collagen, type VI, alpha 1 0.129
Tbx1 T-box 1 0.128
Thbs1 thrombospondin 1 0.127
Col1a1 collagen, type I, alpha 1 0.126
Mfap4 microfibrillar-associated protein 4 0.124
Sfrp2 secreted frizzled-related protein 2 0.121
Fgf5 fibroblast growth factor 5 0.120
Wnt11 wingless-related MMTV integration site 11 0.120
Wnt7b wingless-related MMTV integration site 7B 0.119
Ntf3 neurotrophin 3 0.118
Gli3 GLI-Kruppel family member GLI3 0.115
Phox2b paired-like homeobox 2b 0.114
Col4a2 collagen, type IV, alpha 2 0.109
Chrd chordin 0.108
Cdh11 cadherin 11 0.107
Nkx6-1 NK6 homeobox 1 0.106
Vcan versican 0.105
Cdx1 caudal type homeobox 1 0.105
Nog noggin 0.104
Nrk Nik related kinase 0.104
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.103
Wnt9a wingless-type MMTV integration site 9A 0.103
Vegfa vascular endothelial growth factor A 0.102
Pitx1 paired-like homeodomain transcription factor 1 0.102
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism