The network for 'neuromuscular junction development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

neuromuscular junction development

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.

Name Description Probability Func Analog Organism
trim33 tripartite motif-containing 33 0.255
nf1a neurofibromin 1a 0.095
slc17a6b solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b 0.086
scn8aa sodium channel, voltage-gated, type VIII, alpha a 0.062
lama2 laminin, alpha 2 0.060
hapln3 hyaluronan and proteoglycan link protein 3 0.056
spna2 spectrin alpha 2 0.049
smo smoothened homolog (Drosophila) 0.048
smad1 MAD homolog 1 (Drosophila) 0.047
bmp2b bone morphogenetic protein 2b 0.042
junb jun B proto-oncogene 0.041
atp6v0cb ATPase, H+ transporting, lysosomal, V0 subunit c, b 0.040
nlgn2b neuroligin 2b 0.040
sh3gl1b SH3-domain GRB2-like 1b 0.038
myo6b myosin VIb 0.037
extl3 exostoses (multiple)-like 3 0.034
s1pr2 sphingosine-1-phosphate receptor 2 0.033
ywhag1 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1 0.031
psen1 presenilin 1 0.029
dlg2 discs, large (Drosophila) homolog 2 0.027
stmn2b stathmin-like 2b 0.025
bmpr2b bone morphogenetic protein receptor, type II b (serine/threonine kinase) 0.025
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.025
dmd dystrophin 0.025
boc brother of CDO 0.024
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.024
cdkl1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 0.024
bmpr2a bone morphogenetic protein receptor, type II a (serine/threonine kinase) 0.024
elavl3 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) 0.023
atp1b3a ATPase, Na+/K+ transporting, beta 3a polypeptide 0.023
ptpra protein tyrosine phosphatase, receptor type, A 0.022
ndrg4 N-myc downstream regulated gene 4 0.022
lrrc50 leucine rich repeat containing 50 0.022
atp1a3a ATPase, Na+/K+ transporting, alpha 3a polypeptide 0.022
chrnd cholinergic receptor, nicotinic, delta polypeptide 0.020
pvrl1b poliovirus receptor-related 1b 0.020
arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.020
aldocb aldolase C, fructose-bisphosphate, b 0.018
ela3l elastase 3 like 0.018
atp1a1a.2 ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide 0.018
dag1 dystroglycan 1 0.018
sept6 septin 6 0.017
slc1a2b solute carrier family 1 (glial high affinity glutamate transporter), member 2b 0.016
LOC100535672 trypsin-1-like 0.016
elmo1 engulfment and cell motility 1 (ced-12 homolog, C. elegans) 0.016
junbl jun B proto-oncogene, like 0.016
gng3 guanine nucleotide binding protein (G protein), gamma 3 0.016
rtn1a reticulon 1a 0.016
atf3 activating transcription factor 3 0.015
gpr126 G protein-coupled receptor 126 0.015
atp1b2a ATPase, Na+/K+ transporting, beta 2a polypeptide 0.015
smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.015
tuba1l tubulin, alpha 1, like 0.015
xrcc6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.014
mfn2 mitofusin 2 0.014
myf6 myogenic factor 6 0.014
sncb synuclein, beta 0.014
ntrk2a neurotrophic tyrosine kinase, receptor, type 2a 0.013
acvr1l activin A receptor, type I like 0.013
myd88 myeloid differentiation primary response gene (88) 0.013
rcn1 reticulocalbin 1, EF-hand calcium binding domain 0.013
meis4.1a myeloid ecotropic viral integration site 4.1a 0.013
egr1 early growth response 1 0.013
gap43 growth associated protein 43 0.013
bcl2l1 bcl2-like 1 0.012
sulf2 sulfatase 2 0.012
alcamb activated leukocyte cell adhesion molecule b 0.012
socs3a suppressor of cytokine signaling 3a 0.012
stau2 staufen, RNA binding protein, homolog 2 (Drosophila) 0.012
trpa1b transient receptor potential cation channel, subfamily A, member 1b 0.012
nadl1.2 neural adhesion molecule L1.2 0.012
thsd7a thrombospondin, type I, domain containing 7A 0.012
snap25a synaptosome-associated protein 25a 0.012
igfbp3 insulin-like growth factor binding protein 3 0.012
gad1b glutamate decarboxylase 1b 0.012
foxn4 forkhead box N4 0.012
pdlim3b PDZ and LIM domain 3b 0.011
rac3a ras-related C3 botulinum toxin substrate 3a (rho family, small GTP binding protein Rac3) 0.011
pdia5 protein disulfide isomerase family A, member 5 0.011
npc1 Niemann-Pick disease, type C1 0.011
mef2d myocyte enhancer factor 2d 0.011
atp1b3b ATPase, Na+/K+ transporting, beta 3b polypeptide 0.011
plxnb2a plexin b2a 0.011
si:dkey-202c5.1 si:dkey-202c5.1 0.011
adcyap1b adenylate cyclase activating polypeptide 1b 0.011
gsna gelsolin a 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
spc-1 Protein SPC-1 0.140
chd-7 Protein CHD-7 0.111
ace-1 Protein ACE-1 0.104
ace-3 Protein ACE-3 0.101
mig-15 Protein MIG-15 0.098
aha-1 Protein AHA-1 0.094
eat-4 Protein EAT-4 0.093
unc-9 Protein UNC-9 0.091
R90.1 Protein R90.1 0.087
dbl-1 Protein DBL-1 0.086
clk-2 Protein CLK-2 0.079
ncam-1 Protein NCAM-1 0.078
tag-241 Protein TAG-241 0.078
plc-3 Protein PLC-3 0.076
egl-15 Protein EGL-15 0.073
dpy-22 Protein DPY-22 0.071
hlh-30 Protein HLH-30 0.069
sma-6 Protein SMA-6 0.064
unc-54 Protein UNC-54 0.064
pde-4 Protein PDE-4 0.061
abts-1 Protein ABTS-1 0.061
cdc-42 Protein CDC-42 0.060
egl-8 Protein EGL-8 0.060
ifg-1 Protein IFG-1 0.056
hgrs-1 Protein HGRS-1 0.056
unc-32 Protein UNC-32 0.055
spk-1 Protein SPK-1 0.054
lrp-2 Protein LRP-2 0.053
syg-1 Protein SYG-1 0.052
ace-2 Protein ACE-2 0.052
cap-1 Protein CAP-1 0.051
unc-89 Protein UNC-89 0.050
kin-4 Protein KIN-4 0.049
C05D11.9 Protein C05D11.9 0.049
C17H11.6 Protein C17H11.6 0.049
tbc-9 Protein TBC-9 0.049
miz-1 Protein MIZ-1 0.048
daf-3 Protein DAF-3 0.047
gpb-1 Protein GPB-1 0.047
hmg-1.2 Protein HMG-1.2 0.047
clh-5 Protein CLH-5 0.047
C11E4.6 Protein C11E4.6 0.046
gsp-1 Protein GSP-1 0.046
somi-1 Protein SOMI-1 0.045
him-6 Protein HIM-6 0.045
abl-1 Protein ABL-1 0.045
pry-1 Protein PRY-1 0.045
syd-1 Protein SYD-1 0.045
egl-44 Protein EGL-44 0.045
clp-1 Protein CLP-1 0.045
ptp-3 Protein PTP-3 0.045
dig-1 Protein DIG-1 0.045
paa-1 Protein PAA-1 0.045
ace-4 Protein ACE-4 0.044
crm-1 Protein CRM-1 0.043
C02F5.7 Protein C02F5.7 0.043
lmn-1 Protein LMN-1 0.042
lntl-1 Protein LNTL-1 0.042
myo-6 Protein MYO-6 0.042
nra-1 Protein NRA-1 0.042
nhr-1 Protein NHR-1 0.042
ina-1 Protein INA-1 0.041
R13A5.9 Protein R13A5.9 0.041
Y40C5A.1 Protein Y40C5A.1 0.041
tbc-3 Protein TBC-3 0.041
ced-10 Protein CED-10 0.041
Y42G9A.3 Protein Y42G9A.3 0.040
apb-1 Protein APB-1 0.040
CELE_T04H1.2 Protein T04H1.2 0.040
CELE_F21E9.2 Protein F21E9.2 0.040
ZK484.1 Protein ZK484.1 0.039
dlk-1 Protein DLK-1 0.039
C06G3.6 Protein C06G3.6 0.039
W03G9.3 Protein W03G9.3 0.038
vav-1 Protein VAV-1 0.038
gei-18 Protein GEI-18 0.038
lam-2 Protein LAM-2 0.038
ags-3 Protein AGS-3 0.038
mig-5 Protein MIG-5 0.038
tyr-1 Protein TYR-1 0.038
F49E8.7 Protein F49E8.7 0.038
F25B5.5 Protein F25B5.5 0.038
daf-2 Protein DAF-2 0.037
T08G11.1 Protein T08G11.1 0.037
apa-2 Protein APA-2 0.037
spe-39 Protein SPE-39 0.037
madd-4 Protein MADD-4 0.037
dnj-27 Protein DNJ-27 0.036
dph-2 Protein DPH-2 0.036
max-1 Protein MAX-1 0.036
rskn-1 Protein RSKN-1 0.036
Y54G2A.26 Protein Y54G2A.26 0.036
let-19 Protein LET-19 0.035
C47D12.2 Protein C47D12.2 0.035
dep-1 Protein DEP-1 0.035
abcf-2 Protein ABCF-2 0.035
toca-1 Protein TOCA-1 0.035
let-607 Protein LET-607 0.035
atg-11 Protein ATG-11 0.035
F21A10.2 Protein F21A10.2 0.035
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Cip4 CG15015 gene product from transcript CG15015-RA 1.000
CaMKII Calcium/calmodulin-dependent protein kinase II 1.000
Mad Mothers against dpp 1.000
wit wishful thinking 0.999
TBPH CG10327 gene product from transcript CG10327-RC 0.999
Ank2 Ankyrin 2 0.999
brp bruchpilot 0.999
G-oalpha47A G protein oalpha 47A 0.998
nwk nervous wreck 0.998
Dap160 Dynamin associated protein 160 0.998
Csp Cysteine string protein 0.998
trio CG18214 gene product from transcript CG18214-RA 0.997
ena enabled 0.995
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.994
WASp CG1520 gene product from transcript CG1520-RA 0.994
neuroligin CG13772 gene product from transcript CG13772-RA 0.994
stnB stoned B 0.992
Mob2 CG11711 gene product from transcript CG11711-RC 0.990
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.989
beta-Spec beta Spectrin 0.987
Fak56D Focal Adhesion Kinase 0.983
RhoGAP92B CG4755 gene product from transcript CG4755-RA 0.976
dlp dally-like 0.976
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.975
NetB Netrin-B 0.975
Syx1A Syntaxin 1A 0.975
Acsl Acyl-CoA synthetase long-chain 0.973
par-1 CG8201 gene product from transcript CG8201-RA 0.968
caz cabeza 0.965
Fmr1 CG6203 gene product from transcript CG6203-RC 0.960
Snap25 Synapse protein 25 0.956
cpx complexin 0.953
CG31146 CG31146 gene product from transcript CG31146-RD 0.953
dnc dunce 0.949
mle maleless 0.943
Atg1 Autophagy-specific gene 1 0.942
Hip14 Huntingtin-interacting protein 14 0.942
spas spastin 0.941
Dad Daughters against dpp 0.934
oa2 octopamine receptor 2 0.933
synaptogyrin CG10808 gene product from transcript CG10808-RA 0.933
Akt1 CG4006 gene product from transcript CG4006-RA 0.932
Nrx-1 Neurexin 1 0.931
Frq1 Frequenin 1 0.928
ik2 IkappaB kinase-like 2 0.923
Lrrk Leucine-rich repeat kinase 0.922
Pak PAK-kinase 0.922
ecd ecdysoneless 0.918
jeb jelly belly 0.918
rut rutabaga 0.916
GluRIIA Glutamate receptor IIA 0.911
Nrg Neuroglian 0.901
Octbeta2R CG33976 gene product from transcript CG33976-RA 0.900
faf fat facets 0.898
CG18005 CG18005 gene product from transcript CG18005-RA 0.896
CG10083 CG10083 gene product from transcript CG10083-RA 0.895
Pten CG5671 gene product from transcript CG5671-RB 0.894
Eps-15 Epidermal growth factor receptor pathway substrate clone 15 0.880
cpb capping protein beta 0.873
Syt1 Synaptotagmin 1 0.870
elav embryonic lethal abnormal vision 0.864
fz2 frizzled 2 0.858
Alk CG8250 gene product from transcript CG8250-RA 0.847
tomosyn CG17762 gene product from transcript CG17762-RB 0.833
CrebB-17A Cyclic-AMP response element binding protein B at 17A 0.816
Abl Abl tyrosine kinase 0.816
NFAT NFAT homolog 0.814
mnb minibrain 0.812
unc-104 CG8566 gene product from transcript CG8566-RB 0.809
Ca-alpha1D Ca[2+]-channel protein alpha[[1]] subunit D 0.806
Act57B Actin 57B 0.801
myoglianin CG1838 gene product from transcript CG1838-RD 0.799
Fsn CG4643 gene product from transcript CG4643-RA 0.795
CG9339 CG9339 gene product from transcript CG9339-RG 0.794
cdm cadmus 0.780
comt comatose 0.774
hiw highwire 0.773
sina seven in absentia 0.773
bsk basket 0.771
step steppke 0.751
CCKLR-17D1 CCK-like receptor at 17D1 0.743
Tbh Tyramine beta hydroxylase 0.742
Letm1 CG4589 gene product from transcript CG4589-RB 0.741
brat brain tumor 0.738
BicD Bicaudal D 0.732
Rac1 CG2248 gene product from transcript CG2248-RA 0.731
Amph Amphiphysin 0.727
LanA Laminin A 0.724
RanBPM Ran-binding protein M 0.717
wnd wallenda 0.717
Rab5 Rab-protein 5 0.712
gbb glass bottom boat 0.711
Cdc42 CG12530 gene product from transcript CG12530-RA 0.711
scb scab 0.711
Sra-1 specifically Rac1-associated protein 1 0.710
alpha-Spec alpha Spectrin 0.708
pum pumilio 0.680
Syt4 Synaptotagmin 4 0.679
katanin-60 katanin 60 0.670
wee CG4488 gene product from transcript CG4488-RA 0.658
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Homo sapiens
Name Description Probability Func Analog Organism
FOS FBJ murine osteosarcoma viral oncogene homolog 0.985
NCK1 NCK adaptor protein 1 0.977
FYN FYN oncogene related to SRC, FGR, YES 0.961
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.949
JUN jun proto-oncogene 0.948
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.908
SMAD1 SMAD family member 1 0.891
KIAA1377 KIAA1377 0.878
SPRR2A small proline-rich protein 2A 0.868
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.856
EGFR epidermal growth factor receptor 0.854
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.852
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.821
GRB2 growth factor receptor-bound protein 2 0.812
MAPK12 mitogen-activated protein kinase 12 0.794
KCNJ4 potassium inwardly-rectifying channel, subfamily J, member 4 0.794
DLG4 discs, large homolog 4 (Drosophila) 0.787
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.769
MAPK8 mitogen-activated protein kinase 8 0.754
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.752
FGFR1 fibroblast growth factor receptor 1 0.717
PRMT1 protein arginine methyltransferase 1 0.707
ADAM19 ADAM metallopeptidase domain 19 0.675
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.670
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.663
DAAM1 dishevelled associated activator of morphogenesis 1 0.657
PRKCA protein kinase C, alpha 0.655
SPTAN1 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) 0.638
WIPF1 WAS/WASL interacting protein family, member 1 0.612
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.603
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.594
COL4A2 collagen, type IV, alpha 2 0.593
GDA guanine deaminase 0.592
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.589
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.584
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 0.584
BMP2 bone morphogenetic protein 2 0.582
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.579
FGF1 fibroblast growth factor 1 (acidic) 0.538
GSK3B glycogen synthase kinase 3 beta 0.526
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.502
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.500
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.500
IRF2BP1 interferon regulatory factor 2 binding protein 1 0.487
FASLG Fas ligand (TNF superfamily, member 6) 0.475
HTT huntingtin 0.475
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.472
SH2D4A SH2 domain containing 4A 0.453
CFL1 cofilin 1 (non-muscle) 0.451
SCN5A sodium channel, voltage-gated, type V, alpha subunit 0.444
CLASP1 cytoplasmic linker associated protein 1 0.443
PRKCZ protein kinase C, zeta 0.440
CUL1 cullin 1 0.440
TSC1 tuberous sclerosis 1 0.438
VAV1 vav 1 guanine nucleotide exchange factor 0.422
DUSP1 dual specificity phosphatase 1 0.419
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) 0.418
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.415
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.413
MBNL1 muscleblind-like (Drosophila) 0.412
AXIN1 axin 1 0.409
SYK spleen tyrosine kinase 0.403
LRRK2 leucine-rich repeat kinase 2 0.403
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.403
COX17 COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) 0.388
FOSL1 FOS-like antigen 1 0.388
SOS1 son of sevenless homolog 1 (Drosophila) 0.388
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.380
EPS8 epidermal growth factor receptor pathway substrate 8 0.379
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.373
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.367
JUND jun D proto-oncogene 0.363
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.357
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.353
JUNB jun B proto-oncogene 0.351
IQGAP1 IQ motif containing GTPase activating protein 1 0.350
FUS fused in sarcoma 0.349
MPRIP myosin phosphatase Rho interacting protein 0.349
ATF4 activating transcription factor 4 (tax-responsive enhancer element B67) 0.349
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 0.346
RHOC ras homolog gene family, member C 0.344
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.344
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.342
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.340
MTMR12 myotubularin related protein 12 0.335
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.334
SEPT2 septin 2 0.334
MATK megakaryocyte-associated tyrosine kinase 0.334
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.331
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.329
BMI1 BMI1 polycomb ring finger oncogene 0.324
GAS7 growth arrest-specific 7 0.323
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.320
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.316
FGF10 fibroblast growth factor 10 0.313
SH3RF1 SH3 domain containing ring finger 1 0.305
ADAM17 ADAM metallopeptidase domain 17 0.297
GDF5 growth differentiation factor 5 0.292
PGR progesterone receptor 0.290
MAPT microtubule-associated protein tau 0.284
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.042
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.027
Sirpa signal-regulatory protein alpha 0.021
Nrxn1 neurexin 1 0.015
Cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.013
Atf3 activating transcription factor 3 0.012
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism