The network for 'positive regulation of reproductive process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of reproductive process

Any process that activates or increases the frequency, rate or extent of reproductive process.

Danio rerio
Name Description Probability Func Analog Organism
sim1a single-minded homolog 1a (Drosophila) 0.261
pea3 ETS-domain transcription factor pea3 0.237
gdf9 growth differentiation factor 9 0.207
robo1 roundabout homolog 1 0.180
wt1a wilms tumor 1a 0.176
si:ch211-14a17.7 si:ch211-14a17.7 0.176
pomca proopiomelanocortin a 0.169
inha inhibin, alpha 0.158
nr2f6a nuclear receptor subfamily 2, group F, member 6a 0.141
sox5 SRY-box containing gene 5 0.123
tbx1 T-box 1 0.120
p4ha2 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2 0.108
zp2.2 zona pellucida glycoprotein 2.2 0.095
arpc5b actin related protein 2/3 complex, subunit 5B 0.089
LOC100535118 l-rhamnose-binding lectin CSL3-like 0.087
bmp15 bone morphogenetic protein 15 0.086
wu:fi38e01 wu:fi38e01 0.077
wu:fi42e03 wu:fi42e03 0.073
znf148 zinc finger protein 148 0.073
ncor1 nuclear receptor co-repressor 1 0.073
zgc:64040 zgc:64040 0.069
cyp19a1a cytochrome P450, family 19, subfamily A, polypeptide 1a 0.069
tmpoa thymopoietin a 0.068
skia nuclear oncoprotein skia 0.068
ppardb peroxisome proliferator-activated receptor delta b 0.066
spry4 sprouty (Drosophila) homolog 4 0.065
rarga retinoic acid receptor gamma a 0.063
glceb glucuronyl C5-epimerase b 0.063
zp3a.2 zona pellucida glycoprotein 3a.2 0.063
aim1a absent in melanoma 1a 0.059
arpc5a actin related protein 2/3 complex, subunit 5A 0.058
slit2 slit (Drosophila) homolog 2 0.057
oc90 otoconin 90 0.057
ren renin 0.055
zpcx zona pellucida protein C 0.055
spaw southpaw 0.053
hnf1bb HNF1 homeobox Bb 0.053
tmem88a transmembrane protein 88 a 0.051
zgc:110307 zgc:110307 0.051
cd82a CD82 antigen, a 0.048
arpc4 actin related protein 2/3 complex, subunit 4 0.048
shdb Src homology 2 domain containing transforming protein D, b 0.046
itga3b integrin, alpha 3b 0.046
cacnb4a calcium channel, voltage-dependent, beta 4a subunit 0.046
pcsk5b proprotein convertase subtilisin/kexin type 5b 0.046
sept6 septin 6 0.045
sept2 septin 2 0.045
LOC100333730 l-rhamnose-binding lectin CSL1-like 0.045
zgc:63587 zgc:63587 0.044
zgc:171779 zgc:171779 0.044
chd7 chromodomain helicase DNA binding protein 7 0.044
myl9l myosin, light polypeptide 9, like 0.044
fzd9b frizzled homolog 9b 0.044
sb:eu2468 sb:eu2468 0.044
arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.043
nphs1l nephrosis 1, congenital, Finnish type (nephrin)-like 0.043
smo smoothened homolog (Drosophila) 0.042
rtcd1 RNA terminal phosphate cyclase domain 1 0.042
spry2 sprouty homolog 2 0.041
rasl11b RAS-like, family 11, member B 0.041
LOC100004296 novel protein similar to murine T brachyury (T) 0.041
dhrs3b dehydrogenase/reductase (SDR family) member 3b 0.040
hoxa13a homeo box A13a 0.040
vgll4l vestigial like 4 like 0.040
ptch2 patched 2 0.040
mapk8b mitogen-activated protein kinase 8b 0.040
ext2 exostoses (multiple) 2 0.038
LOC100538023 hypothetical protein LOC100538023 0.038
LOC100331431 hypothetical protein LOC100331431 0.038
osr2 odd-skipped related 2 (Drosophila) 0.037
dvr1 decapentaplegic and Vg-related 1 0.037
axin2 axin 2 (conductin, axil) 0.037
si:ch211-226m16.2 si:ch211-226m16.2 0.037
fzd7a frizzled homolog 7a 0.037
zgc:111868 zgc:111868 0.036
mapk6 mitogen-activated protein kinase 6 0.036
ccbe1 collagen and calcium binding EGF domains 1 0.036
id1 inhibitor of DNA binding 1 0.035
wu:fi34b01 wu:fi34b01 0.035
bambia BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a 0.035
LOC100332505 hypothetical protein LOC100332505 0.035
twist3 twist3 0.035
si:ch211-57k11.10 si:ch211-57k11.10 0.035
tgfb1a transforming growth factor, beta 1a 0.035
gsc goosecoid 0.035
wnt2ba wingless-type MMTV integration site family, member 2Ba 0.035
smad1 MAD homolog 1 (Drosophila) 0.035
LOC100332822 hypothetical protein LOC100332822 0.035
nova2 neuro-oncological ventral antigen 2 0.035
LOC100332229 histone H2A type 1-A-like 0.035
prkab1b protein kinase, AMP-activated, beta 1 non-catalytic subunit, b 0.034
yes1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 0.034
zgc:171818 zgc:171818 0.034
epha2 eph receptor A2 0.033
kirrelb kin of IRRE like b 0.033
zgc:171977 zgc:171977 0.033
rab28 RAB28, member RAS oncogene family 0.033
msnb moesin b 0.033
nrip1b nuclear receptor interacting protein 1b 0.033
si:dkeyp-68f6.1 si:dkeyp-68f6.1 0.033
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
nej nejire 0.655
Rbf Retinoblastoma-family protein 0.165
Akt1 CG4006 gene product from transcript CG4006-RA 0.092
Ras85D Ras oncogene at 85D 0.072
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.060
Atg18 Autophagy-specific gene 18 0.057
scyl scylla 0.044
Dp DP transcription factor 0.040
skd skuld 0.029
rin rasputin 0.023
mip120 Myb-interacting protein 120 0.020
ttv tout-velu 0.020
sxc super sex combs 0.019
E2f E2F transcription factor 0.018
Pten CG5671 gene product from transcript CG5671-RB 0.017
sim single-minded 0.015
shark Src homology 2, ankyrin repeat, tyrosine kinase 0.015
trx trithorax 0.015
simj simjang 0.014
myoglianin CG1838 gene product from transcript CG1838-RD 0.014
Pi3K59F Phosphotidylinositol 3 kinase 59F 0.013
Sply Sphingosine-1-phosphate lyase 0.011
cos costa 0.011
Pi3K21B CG2699 gene product from transcript CG2699-RA 0.011
ci cubitus interruptus 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
SMAD7 SMAD family member 7 0.591
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.477
FKBP1A FK506 binding protein 1A, 12kDa 0.298
E2F6 E2F transcription factor 6 0.187
POU5F1 POU class 5 homeobox 1 0.186
TGFB1 transforming growth factor, beta 1 0.181
PAX3 paired box 3 0.157
BMP2 bone morphogenetic protein 2 0.155
PSEN2 presenilin 2 (Alzheimer disease 4) 0.144
POU3F2 POU class 3 homeobox 2 0.141
E2F4 E2F transcription factor 4, p107/p130-binding 0.095
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.091
GDF5 growth differentiation factor 5 0.082
TFDP1 transcription factor Dp-1 0.071
LRRK2 leucine-rich repeat kinase 2 0.068
MAPK14 mitogen-activated protein kinase 14 0.067
CREBBP CREB binding protein 0.062
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.057
ENG endoglin 0.049
LIN9 lin-9 homolog (C. elegans) 0.045
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.043
SMAD3 SMAD family member 3 0.038
RB1 retinoblastoma 1 0.038
ARID1B AT rich interactive domain 1B (SWI1-like) 0.036
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.036
AKAP11 A kinase (PRKA) anchor protein 11 0.031
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.031
ZMYND11 zinc finger, MYND-type containing 11 0.030
PLAUR plasminogen activator, urokinase receptor 0.027
BMPR1A bone morphogenetic protein receptor, type IA 0.026
PLAU plasminogen activator, urokinase 0.023
CDC14B CDC14 cell division cycle 14 homolog B (S. cerevisiae) 0.022
PROX1 prospero homeobox 1 0.021
E2F1 E2F transcription factor 1 0.021
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.021
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.021
SMAD1 SMAD family member 1 0.019
SMAD2 SMAD family member 2 0.019
PLAT plasminogen activator, tissue 0.018
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.018
TGFB3 transforming growth factor, beta 3 0.018
NCOA6 nuclear receptor coactivator 6 0.017
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.017
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.017
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.017
ZYX zyxin 0.016
KAT2B K(lysine) acetyltransferase 2B 0.016
SMAD4 SMAD family member 4 0.016
PRKG1 protein kinase, cGMP-dependent, type I 0.015
FSTL1 follistatin-like 1 0.014
QKI quaking homolog, KH domain RNA binding (mouse) 0.014
SMAD5 SMAD family member 5 0.014
ATF2 activating transcription factor 2 0.014
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.014
CUX1 cut-like homeobox 1 0.013
MAPK15 mitogen-activated protein kinase 15 0.013
MYBL2 v-myb myeloblastosis viral oncogene homolog (avian)-like 2 0.013
AXIN1 axin 1 0.013
TGFBR1 transforming growth factor, beta receptor 1 0.012
DVL1 dishevelled, dsh homolog 1 (Drosophila) 0.012
WASL Wiskott-Aldrich syndrome-like 0.012
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.012
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.011
AKIP1 A kinase (PRKA) interacting protein 1 0.011
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.010
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Amhr2 anti-Mullerian hormone type 2 receptor 0.915
Gata4 GATA binding protein 4 0.770
Fshr follicle stimulating hormone receptor 0.594
Inhba inhibin beta-A 0.586
Kiss1 KiSS-1 metastasis-suppressor 0.550
Fgfr2 fibroblast growth factor receptor 2 0.547
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.526
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.441
Arid1b AT rich interactive domain 1B (SWI-like) 0.439
Smad4 MAD homolog 4 (Drosophila) 0.414
Apc adenomatosis polyposis coli 0.384
Smad3 MAD homolog 3 (Drosophila) 0.356
Esr1 estrogen receptor 1 (alpha) 0.285
Egr1 early growth response 1 0.275
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.253
Raver2 ribonucleoprotein, PTB-binding 2 0.243
Ptgs2 prostaglandin-endoperoxide synthase 2 0.241
Nos1 nitric oxide synthase 1, neuronal 0.153
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.121
Fst follistatin 0.120
Arid1a AT rich interactive domain 1A (SWI-like) 0.111
Gli3 GLI-Kruppel family member GLI3 0.110
Prkaca protein kinase, cAMP dependent, catalytic, alpha 0.109
Nab2 Ngfi-A binding protein 2 0.105
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.091
Hoxd10 homeobox D10 0.091
Gnrh1 gonadotropin releasing hormone 1 0.078
E2f1 E2F transcription factor 1 0.077
Dhh desert hedgehog 0.076
Adra1b adrenergic receptor, alpha 1b 0.075
Dlg4 discs, large homolog 4 (Drosophila) 0.074
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.072
Acvr2a activin receptor IIA 0.068
Nr0b1 nuclear receptor subfamily 0, group B, member 1 0.068
Egr2 early growth response 2 0.066
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.066
Inhbb inhibin beta-B 0.065
Vasp vasodilator-stimulated phosphoprotein 0.064
Mitf microphthalmia-associated transcription factor 0.063
Kiss1r KISS1 receptor 0.061
Lhx9 LIM homeobox protein 9 0.061
Irs2 insulin receptor substrate 2 0.060
Edn1 endothelin 1 0.059
Lhx3 LIM homeobox protein 3 0.053
Prkch protein kinase C, eta 0.053
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 0.053
Nf1 neurofibromatosis 1 0.052
Utf1 undifferentiated embryonic cell transcription factor 1 0.050
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.049
E2f5 E2F transcription factor 5 0.048
Kit kit oncogene 0.046
Inha inhibin alpha 0.046
Spry4 sprouty homolog 4 (Drosophila) 0.045
Ar androgen receptor 0.045
Plekha5 pleckstrin homology domain containing, family A member 5 0.045
Mrpl3 mitochondrial ribosomal protein L3 0.043
Slc30a3 solute carrier family 30 (zinc transporter), member 3 0.038
Gata5 GATA binding protein 5 0.038
Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 0.038
Plxna4 plexin A4 0.036
Sh3kbp1 SH3-domain kinase binding protein 1 0.034
Nhlh2 nescient helix loop helix 2 0.034
Mn1 meningioma 1 0.033
Kcnab3 potassium voltage-gated channel, shaker-related subfamily, beta member 3 0.032
Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.032
Pcdha10 protocadherin alpha 10 0.029
Flt1 FMS-like tyrosine kinase 1 0.029
Fosb FBJ osteosarcoma oncogene B 0.029
Fos FBJ osteosarcoma oncogene 0.028
Tcfap2a transcription factor AP-2, alpha 0.028
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.028
Homer1 homer homolog 1 (Drosophila) 0.028
Sox7 SRY-box containing gene 7 0.028
Prkar2b protein kinase, cAMP dependent regulatory, type II beta 0.028
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 0.028
Gfra3 glial cell line derived neurotrophic factor family receptor alpha 3 0.027
Bcar1 breast cancer anti-estrogen resistance 1 0.027
Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha 0.027
Fgfr3 fibroblast growth factor receptor 3 0.027
Plxna1 plexin A1 0.026
Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.026
Epb4.1l2 erythrocyte protein band 4.1-like 2 0.026
Spry2 sprouty homolog 2 (Drosophila) 0.026
Drd2 dopamine receptor D2 0.026
Parp1 poly (ADP-ribose) polymerase family, member 1 0.026
Smpd3 sphingomyelin phosphodiesterase 3, neutral 0.025
Arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.025
Sema3c sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.025
Epas1 endothelial PAS domain protein 1 0.025
Adora2a adenosine A2a receptor 0.025
Insr insulin receptor 0.025
Pde3a phosphodiesterase 3A, cGMP inhibited 0.025
Nt5e 5' nucleotidase, ecto 0.025
Ipo5 importin 5 0.025
Pa2g4 proliferation-associated 2G4 0.024
Map3k11 mitogen-activated protein kinase kinase kinase 11 0.024
Gli2 GLI-Kruppel family member GLI2 0.024
Mknk2 MAP kinase-interacting serine/threonine kinase 2 0.023
Atad3a ATPase family, AAA domain containing 3A 0.023
Src Rous sarcoma oncogene 0.023
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
SWI1 Swi1p 0.246
SNF5 Snf5p 0.171
SLT2 Slt2p 0.080
GLN3 Gln3p 0.067
BEM3 Bem3p 0.054
MOB1 Mob1p 0.054
HXT3 Hxt3p 0.043
MIG2 Mig2p 0.042
HAL5 Hal5p 0.040
YPL014W hypothetical protein 0.039
YKR075C hypothetical protein 0.036
ASF2 Asf2p 0.036
MOT1 Mot1p 0.035
PIB2 Pib2p 0.029
MIG3 Mig3p 0.027
STE11 Ste11p 0.026
MIG1 Mig1p 0.024
RGS2 Rgs2p 0.023
ROX1 Rox1p 0.023
SSK2 Ssk2p 0.022
RGD1 Rgd1p 0.022
GAT2 Gat2p 0.021
RTG3 Rtg3p 0.021
VID24 Vid24p 0.020
VAC7 Vac7p 0.019
GIP2 Gip2p 0.019
YLR297W hypothetical protein 0.019
NUP157 Nup157p 0.018
SFL1 Sfl1p 0.018
SBE22 Sbe22p 0.018
LYS5 Lys5p 0.018
YGR035C hypothetical protein 0.017
CAT8 Cat8p 0.017
SNF2 Snf2p 0.017
MSN2 Msn2p 0.016
AFT1 Aft1p 0.015
SWP82 Swp82p 0.015
SUT1 Sut1p 0.015
SMP1 Smp1p 0.015
PHM8 Phm8p 0.015
TRA1 Tra1p 0.015
PHO12 Pho12p 0.014
FPS1 Fps1p 0.014
CSR2 Csr2p 0.013
YPR157W hypothetical protein 0.013
NUP170 Nup170p 0.013
IXR1 Ixr1p 0.013
HRK1 Hrk1p 0.013
NTO1 Nto1p 0.012
TPO2 Tpo2p 0.012
MSG5 Msg5p 0.012
RMA1 Rma1p 0.012
MOT3 Mot3p 0.012
KIC1 Kic1p 0.011
CUP9 Cup9p 0.011
EAR1 Ear1p 0.011
HHF2 Hhf2p 0.011
FAA2 Faa2p 0.010
YAR068W hypothetical protein 0.010
PSK2 Psk2p 0.010
WAR1 War1p 0.010
SWI5 Swi5p 0.010
SRD1 Srd1p 0.010
PTR3 Ptr3p 0.010