IMP

Process View

Homo sapiens

27 genes annotated in human

cellular response to drug

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to drug"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular response to drug" (in gray)

Name	Description	Probability	Func Analog Organism
MT1F	metallothionein 1F	0.969	Human
MT2A	metallothionein 2A	0.901
MT1X	metallothionein 1X	0.628	Human
MT1E	metallothionein 1E	0.508	Human
MT1H	metallothionein 1H	0.499	Human
TP53	tumor protein p53	0.264
IL1R1	interleukin 1 receptor, type I	0.196
AXL	AXL receptor tyrosine kinase	0.158
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.135
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.116
KCNE1	potassium voltage-gated channel, Isk-related family, member 1	0.114
TTR	transthyretin	0.111
ESR1	estrogen receptor 1	0.098
GSTM4	glutathione S-transferase mu 4	0.095
KCNIP2	Kv channel interacting protein 2	0.082
GSTM2	glutathione S-transferase mu 2 (muscle)	0.081
MT1G	metallothionein 1G	0.079	Human
MPDZ	multiple PDZ domain protein	0.078
IRF2	interferon regulatory factor 2	0.068
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.063
MYLK2	myosin light chain kinase 2	0.063
NRP1	neuropilin 1	0.058
RARA	retinoic acid receptor, alpha	0.042
KRT5	keratin 5	0.040
HMGA1	high mobility group AT-hook 1	0.040	Human
IL8	interleukin 8	0.040
PLK3	polo-like kinase 3	0.039
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.036
WWOX	WW domain containing oxidoreductase	0.034
NCOA3	nuclear receptor coactivator 3	0.032
IL1RAP	interleukin 1 receptor accessory protein	0.032
SP1	Sp1 transcription factor	0.031
EP300	E1A binding protein p300	0.029
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.028
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.027
ALDH1A1	aldehyde dehydrogenase 1 family, member A1	0.026
SATB2	SATB homeobox 2	0.026
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.024
MT1M	metallothionein 1M	0.024	Human
HCFC1	host cell factor C1 (VP16-accessory protein)	0.023
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.023
NCOA2	nuclear receptor coactivator 2	0.022
S100B	S100 calcium binding protein B	0.021
KANK2	KN motif and ankyrin repeat domains 2	0.020
AQR	aquarius homolog (mouse)	0.020
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.019
HDAC9	histone deacetylase 9	0.019
PLAT	plasminogen activator, tissue	0.019
HDAC4	histone deacetylase 4	0.018
PGF	placental growth factor	0.018
EPT1	ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)	0.018
RBM4	RNA binding motif protein 4	0.018
EPAS1	endothelial PAS domain protein 1	0.017
MEF2A	myocyte enhancer factor 2A	0.017
PPP5C	protein phosphatase 5, catalytic subunit	0.017
KAT2B	K(lysine) acetyltransferase 2B	0.017
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.016
PRKCE	protein kinase C, epsilon	0.016
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.016
PPP3R1	protein phosphatase 3, regulatory subunit B, alpha	0.016
GSTM3	glutathione S-transferase mu 3 (brain)	0.016
POU2F1	POU class 2 homeobox 1	0.016
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.016	Human
KSR1	kinase suppressor of ras 1	0.015
MT1A	metallothionein 1A	0.015
EGR3	early growth response 3	0.014
KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1	0.014
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.014	Human
MYST3	MYST histone acetyltransferase (monocytic leukemia) 3	0.014
IL1R2	interleukin 1 receptor, type II	0.014
AFF1	AF4/FMR2 family, member 1	0.014
PTEN	phosphatase and tensin homolog	0.014
IL1B	interleukin 1, beta	0.013
LNX1	ligand of numb-protein X 1	0.013
MYOD1	myogenic differentiation 1	0.013
CABLES1	Cdk5 and Abl enzyme substrate 1	0.013
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.013
YAP1	Yes-associated protein 1	0.013
KCNIP1	Kv channel interacting protein 1	0.013
SPDEF	SAM pointed domain containing ets transcription factor	0.012
AFF4	AF4/FMR2 family, member 4	0.012
FEM1B	fem-1 homolog b (C. elegans)	0.012
FHL1	four and a half LIM domains 1	0.012
IL1RN	interleukin 1 receptor antagonist	0.012	Human
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.012
DYNLT1	dynein, light chain, Tctex-type 1	0.012
SSTR3	somatostatin receptor 3	0.011
EGR2	early growth response 2	0.011
ORM1	orosomucoid 1	0.011
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.011
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.011
CPNE6	copine VI (neuronal)	0.011
SOD2	superoxide dismutase 2, mitochondrial	0.010
PRRC2B	proline-rich coiled-coil 2B	0.010
ODF1	outer dense fiber of sperm tails 1	0.010
FOXO1	forkhead box O1	0.010
CCNT1	cyclin T1	0.010
FGF3	fibroblast growth factor 3	0.010