IMP

Process View

Homo sapiens

15 genes annotated in human

regulation of collagen metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of collagen metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of collagen metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.994
TEK	TEK tyrosine kinase, endothelial	0.984
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.970
BMPR1A	bone morphogenetic protein receptor, type IA	0.798
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.797
FSTL1	follistatin-like 1	0.739
ENG	endoglin	0.323
PLEC	plectin	0.254
CYTH1	cytohesin 1	0.252
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.208
TGFBR1	transforming growth factor, beta receptor 1	0.184
FN1	fibronectin 1	0.147
ITGA6	integrin, alpha 6	0.146
FLNB	filamin B, beta	0.136
CAV1	caveolin 1, caveolae protein, 22kDa	0.132
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.126
NRP1	neuropilin 1	0.122
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.118
CYR61	cysteine-rich, angiogenic inducer, 61	0.101
S100B	S100 calcium binding protein B	0.090
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.075
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.074
CXCL12	chemokine (C-X-C motif) ligand 12	0.072
FGG	fibrinogen gamma chain	0.064
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.057
IL6R	interleukin 6 receptor	0.057
COL6A1	collagen, type VI, alpha 1	0.055
MYO10	myosin X	0.049
FHL2	four and a half LIM domains 2	0.047
ALB	albumin	0.043
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.041
CALD1	caldesmon 1	0.039
IL6	interleukin 6 (interferon, beta 2)	0.039
FGA	fibrinogen alpha chain	0.039
C1S	complement component 1, s subcomponent	0.037
COL17A1	collagen, type XVII, alpha 1	0.036
FGF18	fibroblast growth factor 18	0.035
F3	coagulation factor III (thromboplastin, tissue factor)	0.034
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.034
THBS1	thrombospondin 1	0.031
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.031
HSPG2	heparan sulfate proteoglycan 2	0.030
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.029
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.027
CD81	CD81 molecule	0.026
FCGRT	Fc fragment of IgG, receptor, transporter, alpha	0.026
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.024
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.024
CFD	complement factor D (adipsin)	0.023
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.023
PDIA3	protein disulfide isomerase family A, member 3	0.022
CD14	CD14 molecule	0.021
CD9	CD9 molecule	0.021
FBLN1	fibulin 1	0.021
CD63	CD63 molecule	0.020
FBN1	fibrillin 1	0.020
DCN	decorin	0.019
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.018
PTEN	phosphatase and tensin homolog	0.018
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.018
CXCL2	chemokine (C-X-C motif) ligand 2	0.018
BMP4	bone morphogenetic protein 4	0.018
CCL22	chemokine (C-C motif) ligand 22	0.017
CCDC90B	coiled-coil domain containing 90B	0.017
C1R	complement component 1, r subcomponent	0.017
GRB7	growth factor receptor-bound protein 7	0.016
TGFBR3	transforming growth factor, beta receptor III	0.016
TIMP1	TIMP metallopeptidase inhibitor 1	0.016
PLG	plasminogen	0.016
VAV1	vav 1 guanine nucleotide exchange factor	0.016
LAMC2	laminin, gamma 2	0.015
EDN1	endothelin 1	0.015
FYN	FYN oncogene related to SRC, FGR, YES	0.015
ELN	elastin	0.015
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.014
PXN	paxillin	0.014
DPT	dermatopontin	0.014
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.014	Rat
CALR	calreticulin	0.013
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.013
NOG	noggin	0.013
FGF4	fibroblast growth factor 4	0.013
GSN	gelsolin	0.013
LAMB1	laminin, beta 1	0.013
IGF1	insulin-like growth factor 1 (somatomedin C)	0.012
PDGFA	platelet-derived growth factor alpha polypeptide	0.012
RARRES2	retinoic acid receptor responder (tazarotene induced) 2	0.012
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.012
SLA	Src-like-adaptor	0.012
CST1	cystatin SN	0.012	Human
HGFAC	HGF activator	0.012
CLU	clusterin	0.012
PTGDS	prostaglandin D2 synthase 21kDa (brain)	0.012
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.012
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.011
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.011
FMOD	fibromodulin	0.011
RANBP9	RAN binding protein 9	0.011
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.011
CTSA	cathepsin A	0.011
WIF1	WNT inhibitory factor 1	0.011
CXCL14	chemokine (C-X-C motif) ligand 14	0.011
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.011
CCL11	chemokine (C-C motif) ligand 11	0.011
LAMB3	laminin, beta 3	0.010
TGFB2	transforming growth factor, beta 2	0.010	Human
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.010
PAX8	paired box 8	0.010