IMP
Process View
nuclear transcribed mrna catabolic process deadenylation dependent decay
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "nuclear transcribed mrna catabolic process deadenylation dependent decay"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 1.000 | Yeast Mouse | |
| TOB1 | transducer of ERBB2, 1 | 1.000 | ||
| TNRC6A | trinucleotide repeat containing 6A | 0.999 | Human | |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) | 0.992 | Yeast Mouse | |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.987 | ||
| TNRC6C | trinucleotide repeat containing 6C | 0.978 | ||
| DCP1A | DCP1 decapping enzyme homolog A (S. cerevisiae) | 0.974 | ||
| TNRC6B | trinucleotide repeat containing 6B | 0.873 | ||
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | 0.765 | ||
| EXOSC7 | exosome component 7 | 0.743 | ||
| EIF2C1 | eukaryotic translation initiation factor 2C, 1 | 0.734 | ||
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.705 | ||
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.686 | ||
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.681 | Human | |
| PAIP2 | poly(A) binding protein interacting protein 2 | 0.575 | ||
| PCBP2 | poly(rC) binding protein 2 | 0.573 | ||
| EXOSC10 | exosome component 10 | 0.412 | ||
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.358 | Human Yeast Mouse | |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.347 | ||
| EIF2C2 | eukaryotic translation initiation factor 2C, 2 | 0.316 | Mouse | |
| CNOT6 | CCR4-NOT transcription complex, subunit 6 | 0.290 | ||
| GSPT1 | G1 to S phase transition 1 | 0.272 | Yeast | |
| YBX1 | Y box binding protein 1 | 0.211 | ||
| EXOSC3 | exosome component 3 | 0.172 | ||
| NOXA1 | NADPH oxidase activator 1 | 0.169 | ||
| EIF2C4 | eukaryotic translation initiation factor 2C, 4 | 0.165 | ||
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.161 | ||
| PCBP1 | poly(rC) binding protein 1 | 0.150 | ||
| BTG2 | BTG family, member 2 | 0.119 | ||
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.091 | ||
| DICER1 | dicer 1, ribonuclease type III | 0.091 | ||
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.085 | ||
| EXOSC2 | exosome component 2 | 0.082 | ||
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 0.077 | ||
| EXOSC1 | exosome component 1 | 0.074 | ||
| SMG1 | SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) | 0.055 | ||
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.054 | ||
| PRKCZ | protein kinase C, zeta | 0.050 | Yeast | |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | 0.049 | Yeast | |
| PARD6A | par-6 partitioning defective 6 homolog alpha (C. elegans) | 0.044 | ||
| EXOSC4 | exosome component 4 | 0.044 | Yeast | |
| EIF2C3 | eukaryotic translation initiation factor 2C, 3 | 0.039 | ||
| CARD11 | caspase recruitment domain family, member 11 | 0.038 | ||
| KLF4 | Kruppel-like factor 4 (gut) | 0.036 | ||
| ATXN2 | ataxin 2 | 0.033 | ||
| POLR2E | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa | 0.032 | ||
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.029 | ||
| PARD3 | par-3 partitioning defective 3 homolog (C. elegans) | 0.027 | ||
| DIS3L | DIS3 mitotic control homolog (S. cerevisiae)-like | 0.026 | ||
| PAIP1 | poly(A) binding protein interacting protein 1 | 0.025 | ||
| IER2 | immediate early response 2 | 0.023 | ||
| CNOT10 | CCR4-NOT transcription complex, subunit 10 | 0.020 | ||
| PRKCB | protein kinase C, beta | 0.019 | ||
| STAU1 | staufen, RNA binding protein, homolog 1 (Drosophila) | 0.018 | ||
| GSPT2 | G1 to S phase transition 2 | 0.018 | Yeast | |
| TSC22D1 | TSC22 domain family, member 1 | 0.017 | ||
| PICK1 | protein interacting with PRKCA 1 | 0.017 | ||
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 | 0.017 | ||
| SBF1 | SET binding factor 1 | 0.016 | ||
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.016 | Human | |
| DUSP1 | dual specificity phosphatase 1 | 0.015 | ||
| CDCP1 | CUB domain containing protein 1 | 0.014 | ||
| SH3RF1 | SH3 domain containing ring finger 1 | 0.014 | ||
| PMS2 | PMS2 postmeiotic segregation increased 2 (S. cerevisiae) | 0.014 | ||
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.014 | ||
| TOB2 | transducer of ERBB2, 2 | 0.013 | ||
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.012 | ||
| EXOSC5 | exosome component 5 | 0.012 | ||
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.012 | ||
| CNOT3 | CCR4-NOT transcription complex, subunit 3 | 0.012 | Yeast | |
| EIF4B | eukaryotic translation initiation factor 4B | 0.011 | ||
| BARD1 | BRCA1 associated RING domain 1 | 0.011 | ||
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.010 |