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Homo sapiens

23 genes annotated in human

artery disease

DOID:0050828

A vascular disease that is located in an artery.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "artery disease"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "artery disease" (in gray)

Name	Description	Probability	Func Analog Organism
NOSTRIN	nitric oxide synthase trafficker	1.000
RFX1	regulatory factor X, 1 (influences HLA class II expression)	0.994
GUCY1B3	guanylate cyclase 1, soluble, beta 3	0.951	Human
PRKG1	protein kinase, cGMP-dependent, type I	0.945
FGF10	fibroblast growth factor 10	0.932
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.900
MYH11	myosin, heavy chain 11, smooth muscle	0.827
ACTA2	actin, alpha 2, smooth muscle, aorta	0.581
MRVI1	murine retrovirus integration site 1 homolog	0.485
MAPK8	mitogen-activated protein kinase 8	0.478
FGF1	fibroblast growth factor 1 (acidic)	0.426
FGF7	fibroblast growth factor 7	0.413
ACVR1	activin A receptor, type I	0.395	Human
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.305
BMPR1A	bone morphogenetic protein receptor, type IA	0.171	Human
CNN1	calponin 1, basic, smooth muscle	0.127
ARRB1	arrestin, beta 1	0.123
CALD1	caldesmon 1	0.122
PARP9	poly (ADP-ribose) polymerase family, member 9	0.098
ACTC1	actin, alpha, cardiac muscle 1	0.097	Human
CTTN	cortactin	0.091
LMOD1	leiomodin 1 (smooth muscle)	0.086
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.079
FGA	fibrinogen alpha chain	0.075
GCDH	glutaryl-CoA dehydrogenase	0.072
PRELP	proline/arginine-rich end leucine-rich repeat protein	0.070
ACTG2	actin, gamma 2, smooth muscle, enteric	0.068	Human
FGFR1	fibroblast growth factor receptor 1	0.062	Human
FGB	fibrinogen beta chain	0.060
RBMS3	RNA binding motif, single stranded interacting protein 3	0.059
PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	0.059
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.045
DCTN1	dynactin 1	0.045
C5orf56	chromosome 5 open reading frame 56	0.044
CD34	CD34 molecule	0.043
MYL9	myosin, light chain 9, regulatory	0.042
ALB	albumin	0.039
PINK1	PTEN induced putative kinase 1	0.039
SOD3	superoxide dismutase 3, extracellular	0.038
IGF1	insulin-like growth factor 1 (somatomedin C)	0.037
TNS1	tensin 1	0.035
CBX2	chromobox homolog 2	0.034
MYOC	myocilin, trabecular meshwork inducible glucocorticoid response	0.033
KCNMB1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.031
TPM1	tropomyosin 1 (alpha)	0.031
SLX1B	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)	0.030
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.030
ALOX5	arachidonate 5-lipoxygenase	0.030
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.029	Human
SQSTM1	sequestosome 1	0.029
FKBP10	FK506 binding protein 10, 65 kDa	0.028
MKRN1	makorin ring finger protein 1	0.027
FMOD	fibromodulin	0.026
RGS5	regulator of G-protein signaling 5	0.026
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.026
LPP	LIM domain containing preferred translocation partner in lipoma	0.026
WISP2	WNT1 inducible signaling pathway protein 2	0.025
APOE	apolipoprotein E	0.025
ATP2B4	ATPase, Ca++ transporting, plasma membrane 4	0.024
PLD3	phospholipase D family, member 3	0.024
HLA-C	major histocompatibility complex, class I, C	0.022
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.022
DARC	Duffy blood group, chemokine receptor	0.022
SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	0.022
CNN2	calponin 2	0.022
ANGPT1	angiopoietin 1	0.021
CSRP1	cysteine and glycine-rich protein 1	0.021
PLA2G5	phospholipase A2, group V	0.021
BMP2	bone morphogenetic protein 2	0.021
MAP2K7	mitogen-activated protein kinase kinase 7	0.021
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.021
OLFML1	olfactomedin-like 1	0.020
F10	coagulation factor X	0.020	Human
LRRC32	leucine rich repeat containing 32	0.019
PLAT	plasminogen activator, tissue	0.019
ITGA8	integrin, alpha 8	0.019
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.018
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.018
NLRC5	NLR family, CARD domain containing 5	0.018
CCL21	chemokine (C-C motif) ligand 21	0.018
SYNPO2	synaptopodin 2	0.018
ATOH8	atonal homolog 8 (Drosophila)	0.018
KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.017
TBX2	T-box 2	0.017
FOXF2	forkhead box F2	0.017	Human
DLC1	deleted in liver cancer 1	0.017
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.017
CLSTN1	calsyntenin 1	0.017
CSNK2A2	casein kinase 2, alpha prime polypeptide	0.017
RASL12	RAS-like, family 12	0.017
FBLN1	fibulin 1	0.017
TAGLN	transgelin	0.016
FAM65A	family with sequence similarity 65, member A	0.016
NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive	0.016
DTX3L	deltex 3-like (Drosophila)	0.016
POSTN	periostin, osteoblast specific factor	0.016
UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	0.016
HSPB6	heat shock protein, alpha-crystallin-related, B6	0.015
SORBS1	sorbin and SH3 domain containing 1	0.015
ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)	0.015
KANK2	KN motif and ankyrin repeat domains 2	0.015
MFAP4	microfibrillar-associated protein 4	0.015
RAB5B	RAB5B, member RAS oncogene family	0.015
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.015
AGTR1	angiotensin II receptor, type 1	0.015
CXCL12	chemokine (C-X-C motif) ligand 12	0.014
MAP1B	microtubule-associated protein 1B	0.014
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.014
ACTR1B	ARP1 actin-related protein 1 homolog B, centractin beta (yeast)	0.014
ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	0.014
SLX4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)	0.014
RHOJ	ras homolog gene family, member J	0.014
MFAP5	microfibrillar associated protein 5	0.014
PARVA	parvin, alpha	0.014
TCTEX1D2	Tctex1 domain containing 2	0.013
ACOX2	acyl-CoA oxidase 2, branched chain	0.013
ALDH2	aldehyde dehydrogenase 2 family (mitochondrial)	0.013
PPP1R12B	protein phosphatase 1, regulatory (inhibitor) subunit 12B	0.013
EVL	Enah/Vasp-like	0.013
DAAM2	dishevelled associated activator of morphogenesis 2	0.013
MAST1	microtubule associated serine/threonine kinase 1	0.013
PGM5	phosphoglucomutase 5	0.013
PAMR1	peptidase domain containing associated with muscle regeneration 1	0.013
VPS39	vacuolar protein sorting 39 homolog (S. cerevisiae)	0.013
FAM190B	family with sequence similarity 190, member B	0.013
DPT	dermatopontin	0.012
ANXA6	annexin A6	0.012
SPAG9	sperm associated antigen 9	0.012
SLIT3	slit homolog 3 (Drosophila)	0.012
APOB	apolipoprotein B (including Ag(x) antigen)	0.012
C6	complement component 6	0.012
NUPR1	nuclear protein, transcriptional regulator, 1	0.012
OPTN	optineurin	0.012
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.012
CHRDL1	chordin-like 1	0.012
GRK5	G protein-coupled receptor kinase 5	0.012
PLN	phospholamban	0.012
LAPTM5	lysosomal protein transmembrane 5	0.012
LYVE1	lymphatic vessel endothelial hyaluronan receptor 1	0.012
ZNFX1	zinc finger, NFX1-type containing 1	0.011
RARRES2	retinoic acid receptor responder (tazarotene induced) 2	0.011
BMPR1B	bone morphogenetic protein receptor, type IB	0.011	Human
NFIB	nuclear factor I/B	0.011
XAF1	XIAP associated factor 1	0.011
PLEC	plectin	0.011
RDH13	retinol dehydrogenase 13 (all-trans/9-cis)	0.011
GNG8	guanine nucleotide binding protein (G protein), gamma 8	0.011
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.011
FHL5	four and a half LIM domains 5	0.011
LIMS2	LIM and senescent cell antigen-like domains 2	0.011
JAM3	junctional adhesion molecule 3	0.011
TRAK2	trafficking protein, kinesin binding 2	0.011
LCP1	lymphocyte cytosolic protein 1 (L-plastin)	0.011
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.011	Human
SLA	Src-like-adaptor	0.011
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.011
GUCY1A2	guanylate cyclase 1, soluble, alpha 2	0.011	Human
APOD	apolipoprotein D	0.011
ECM2	extracellular matrix protein 2, female organ and adipocyte specific	0.011
XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.011
RCAN2	regulator of calcineurin 2	0.011
HP	haptoglobin	0.011
KL	klotho	0.011
NOTCH3	notch 3	0.011
EDIL3	EGF-like repeats and discoidin I-like domains 3	0.011
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.011
COL14A1	collagen, type XIV, alpha 1	0.011
GPR116	G protein-coupled receptor 116	0.011
LGALS3BP	lectin, galactoside-binding, soluble, 3 binding protein	0.011
ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8	0.011
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.011
SCN7A	sodium channel, voltage-gated, type VII, alpha	0.010
PDE5A	phosphodiesterase 5A, cGMP-specific	0.010
PDE3A	phosphodiesterase 3A, cGMP-inhibited	0.010
MRFAP1	Morf4 family associated protein 1	0.010
CPB2	carboxypeptidase B2 (plasma)	0.010
SVIL	supervillin	0.010
WFDC1	WAP four-disulfide core domain 1	0.010
AHSG	alpha-2-HS-glycoprotein	0.010
MBTPS1	membrane-bound transcription factor peptidase, site 1	0.010
SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	0.010	Human
LAMA4	laminin, alpha 4	0.010
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.010
HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	0.010
SCARB2	scavenger receptor class B, member 2	0.010
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.010
CRYAB	crystallin, alpha B	0.010
ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.010
AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.010
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.009
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.007
PRKCH	protein kinase C, eta	0.007
MYLK	myosin light chain kinase	0.006
F5	coagulation factor V (proaccelerin, labile factor)	0.006
STOX1	storkhead box 1	0.005
NOS3	nitric oxide synthase 3 (endothelial cell)	0.005
ADD1	adducin 1 (alpha)	0.004
ECE1	endothelin converting enzyme 1	0.004
FGFR2	fibroblast growth factor receptor 2	0.003
EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)	0.003
GNB3	guanine nucleotide binding protein (G protein), beta polypeptide 3	0.003
FOXF1	forkhead box F1	0.003
GUCY1A3	guanylate cyclase 1, soluble, alpha 3	0.002
F2	coagulation factor II (thrombin)	0.001
RNF213	ring finger protein 213	0.001
ALOX5AP	arachidonate 5-lipoxygenase-activating protein	0.001