IMP

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Homo sapiens

26 genes annotated in human

endocrine system disease

DOID:28

A disease of anatomical entity that is located in endocrine glands which secretes a type of hormone directly into the bloodstream to regulate the body.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "endocrine system disease"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "endocrine system disease" (in gray)

Name	Description	Probability	Func Analog Organism
CREBBP	CREB binding protein	0.918
TBX5	T-box 5	0.745
NCOA2	nuclear receptor coactivator 2	0.673
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.331
FOXO1	forkhead box O1	0.246
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.198
SMAD1	SMAD family member 1	0.188
CHD8	chromodomain helicase DNA binding protein 8	0.187	Human
FGF1	fibroblast growth factor 1 (acidic)	0.159
MYST2	MYST histone acetyltransferase 2	0.156
FHL2	four and a half LIM domains 2	0.150
NKX2-1	NK2 homeobox 1	0.138	Human
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.136
CTR9	Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.135
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.125
TNRC6A	trinucleotide repeat containing 6A	0.117
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.110
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.096
FRS2	fibroblast growth factor receptor substrate 2	0.095
FGF2	fibroblast growth factor 2 (basic)	0.076
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.057
GATA4	GATA binding protein 4	0.055
TARBP2	TAR (HIV-1) RNA binding protein 2	0.046
CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.046
NCOA6	nuclear receptor coactivator 6	0.046
LAT	linker for activation of T cells	0.044
KAT5	K(lysine) acetyltransferase 5	0.039
FGFR2	fibroblast growth factor receptor 2	0.039	Human
KAT2B	K(lysine) acetyltransferase 2B	0.034
NCOA1	nuclear receptor coactivator 1	0.028
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.027
PLCG1	phospholipase C, gamma 1	0.027
FOXA1	forkhead box A1	0.027	Human
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.024
NOSTRIN	nitric oxide synthase trafficker	0.023
CSE1L	CSE1 chromosome segregation 1-like (yeast)	0.021
MED1	mediator complex subunit 1	0.018
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.016
FOXO3	forkhead box O3	0.016
LEO1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.016
DHX58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.015	Human
DAXX	death-domain associated protein	0.015
APC	adenomatous polyposis coli	0.014
PPARA	peroxisome proliferator-activated receptor alpha	0.014
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.013
NPAS1	neuronal PAS domain protein 1	0.013
TCF4	transcription factor 4	0.013
ITFG1	integrin alpha FG-GAP repeat containing 1	0.013
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.013
GLIS2	GLIS family zinc finger 2	0.013
RARA	retinoic acid receptor, alpha	0.013	Human
HNF1A	HNF1 homeobox A	0.013
LHX1	LIM homeobox 1	0.012
TBX1	T-box 1	0.012
INSL3	insulin-like 3 (Leydig cell)	0.012
LBX1	ladybird homeobox 1	0.012
USP1	ubiquitin specific peptidase 1	0.012
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.012
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.011
MRPL3	mitochondrial ribosomal protein L3	0.011
SRSF1	serine/arginine-rich splicing factor 1	0.011
PAICS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	0.011
CCT2	chaperonin containing TCP1, subunit 2 (beta)	0.011
SHB	Src homology 2 domain containing adaptor protein B	0.011
FOXJ1	forkhead box J1	0.011
ABCE1	ATP-binding cassette, sub-family E (OABP), member 1	0.011
DRD2	dopamine receptor D2	0.010
HNF4A	hepatocyte nuclear factor 4, alpha	0.010
UCHL5	ubiquitin carboxyl-terminal hydrolase L5	0.010
AR	androgen receptor	0.010
PDX1	pancreatic and duodenal homeobox 1	0.007
SLC5A5	solute carrier family 5 (sodium iodide symporter), member 5	0.005
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.005
FGF8	fibroblast growth factor 8 (androgen-induced)	0.005
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.005
GCM2	glial cells missing homolog 2 (Drosophila)	0.005
PAX8	paired box 8	0.005
DUOX2	dual oxidase 2	0.005
CYP11A1	cytochrome P450, family 11, subfamily A, polypeptide 1	0.004
TPO	thyroid peroxidase	0.004
DUOXA2	dual oxidase maturation factor 2	0.004
PTH	parathyroid hormone	0.004
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.004
CYP11B1	cytochrome P450, family 11, subfamily B, polypeptide 1	0.004
PROKR2	prokineticin receptor 2	0.004
PROK2	prokineticin 2	0.004
AVP	arginine vasopressin	0.004
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.003
FGFR1	fibroblast growth factor receptor 1	0.003
AMH	anti-Mullerian hormone	0.003
AMHR2	anti-Mullerian hormone receptor, type II	0.003
CHD7	chromodomain helicase DNA binding protein 7	0.003
TSHB	thyroid stimulating hormone, beta	0.003
DICER1	dicer 1, ribonuclease type III	0.002
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.001