IMP

Process View

Homo sapiens

16 genes annotated in human

regulation of membrane repolarization

Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of membrane repolarization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of membrane repolarization" (in gray)

Name	Description	Probability	Func Analog Organism
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	1.000	Human
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	1.000	Human
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.999	Human
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.997	Human
KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1	0.991	Human
DLG4	discs, large homolog 4 (Drosophila)	0.960
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.917
MPZL3	myelin protein zero-like 3	0.899	Human
MPZL2	myelin protein zero-like 2	0.888	Human
KCNIP2	Kv channel interacting protein 2	0.874
SCN5A	sodium channel, voltage-gated, type V, alpha subunit	0.830
LIN7B	lin-7 homolog B (C. elegans)	0.790
ACTN2	actinin, alpha 2	0.761
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.702
TJP1	tight junction protein 1 (zona occludens 1)	0.641
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.628
SNTG2	syntrophin, gamma 2	0.625	Human
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.612	Human
MAPK12	mitogen-activated protein kinase 12	0.571
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.515	Human
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.426	Human
ZFYVE9	zinc finger, FYVE domain containing 9	0.357
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.302	Human
SPTB	spectrin, beta, erythrocytic	0.290
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.222
MYOZ1	myozenin 1	0.163
DMD	dystrophin	0.132
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.117
ANKRD13A	ankyrin repeat domain 13A	0.109
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.107
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.107	Human
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.095
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.091
KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1	0.086
EHD1	EH-domain containing 1	0.084
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.084	Human
CLCN3	chloride channel 3	0.079
FBXL15	F-box and leucine-rich repeat protein 15	0.078
KCNIP1	Kv channel interacting protein 1	0.073
KCNA5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.072
RYR2	ryanodine receptor 2 (cardiac)	0.066
KCNH1	potassium voltage-gated channel, subfamily H (eag-related), member 1	0.065	Human
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.062
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.058
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.057
MARK2	MAP/microtubule affinity-regulating kinase 2	0.054
BAI1	brain-specific angiogenesis inhibitor 1	0.053
KCNG3	potassium voltage-gated channel, subfamily G, member 3	0.049	Human
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.043
RHAG	Rh-associated glycoprotein	0.040
FRS2	fibroblast growth factor receptor substrate 2	0.039
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.037
CAV1	caveolin 1, caveolae protein, 22kDa	0.035
RHOA	ras homolog gene family, member A	0.035
POU5F1	POU class 5 homeobox 1	0.034
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.034
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.033
BSN	bassoon (presynaptic cytomatrix protein)	0.031
ATP2B3	ATPase, Ca++ transporting, plasma membrane 3	0.027
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.026	Human
HRH3	histamine receptor H3	0.024
WNK1	WNK lysine deficient protein kinase 1	0.024
DPP6	dipeptidyl-peptidase 6	0.023
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.023
SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)	0.021
KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4	0.021	Human
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.021
KCNB2	potassium voltage-gated channel, Shab-related subfamily, member 2	0.020	Human
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.020	Human
ING1	inhibitor of growth family, member 1	0.020
SEZ6L	seizure related 6 homolog (mouse)-like	0.020
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.020
USP2	ubiquitin specific peptidase 2	0.020
CCKBR	cholecystokinin B receptor	0.019
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.019
RNF168	ring finger protein 168	0.019
KCNJ10	potassium inwardly-rectifying channel, subfamily J, member 10	0.018	Human
BAD	BCL2-associated agonist of cell death	0.018
KCNJ6	potassium inwardly-rectifying channel, subfamily J, member 6	0.018	Human
KCNJ16	potassium inwardly-rectifying channel, subfamily J, member 16	0.017	Human
UBQLN2	ubiquilin 2	0.017
GRM7	glutamate receptor, metabotropic 7	0.016
KCNA2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.016	Human
KLF5	Kruppel-like factor 5 (intestinal)	0.016
SLITRK3	SLIT and NTRK-like family, member 3	0.016
SMAD1	SMAD family member 1	0.016
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.016
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.016
ADCYAP1	adenylate cyclase activating polypeptide 1 (pituitary)	0.016
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.016
NLGN1	neuroligin 1	0.014
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.014
RGS6	regulator of G-protein signaling 6	0.014
SMAD4	SMAD family member 4	0.014
CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.014
SMAD5	SMAD family member 5	0.014
SOX7	SRY (sex determining region Y)-box 7	0.014
CYP46A1	cytochrome P450, family 46, subfamily A, polypeptide 1	0.014
SYN2	synapsin II	0.014
VMP1	vacuole membrane protein 1	0.014
GRIK1	glutamate receptor, ionotropic, kainate 1	0.013
CADM3	cell adhesion molecule 3	0.013
OPCML	opioid binding protein/cell adhesion molecule-like	0.013
GPR26	G protein-coupled receptor 26	0.013
CCDC127	coiled-coil domain containing 127	0.013
SLIT1	slit homolog 1 (Drosophila)	0.013
KCND2	potassium voltage-gated channel, Shal-related subfamily, member 2	0.013	Human
KCNAB1	potassium voltage-gated channel, shaker-related subfamily, beta member 1	0.013
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.013
ST8SIA5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5	0.013
CXXC5	CXXC finger protein 5	0.013
C1QL1	complement component 1, q subcomponent-like 1	0.013
SCN3B	sodium channel, voltage-gated, type III, beta	0.013
NRXN1	neurexin 1	0.012
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.012
CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.012
SLC17A7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.012
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.012
CPLX2	complexin 2	0.012
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.012
DISC1	disrupted in schizophrenia 1	0.012
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A	0.012
KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.012
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.012
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.012
KCNF1	potassium voltage-gated channel, subfamily F, member 1	0.011	Human
KCNQ3	potassium voltage-gated channel, KQT-like subfamily, member 3	0.011	Human
SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5	0.011
CNKSR2	connector enhancer of kinase suppressor of Ras 2	0.011
MAP1A	microtubule-associated protein 1A	0.011
FXYD7	FXYD domain containing ion transport regulator 7	0.011
KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.011	Human
ADRA1D	adrenergic, alpha-1D-, receptor	0.011
ADAM11	ADAM metallopeptidase domain 11	0.011
KCNJ9	potassium inwardly-rectifying channel, subfamily J, member 9	0.011	Human
C1orf61	chromosome 1 open reading frame 61	0.011
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.011	Human
NECAB2	N-terminal EF-hand calcium binding protein 2	0.011
NTSR2	neurotensin receptor 2	0.011
PDZK1	PDZ domain containing 1	0.011
CAMK2B	calcium/calmodulin-dependent protein kinase II beta	0.011
DDN	dendrin	0.011
KCND3	potassium voltage-gated channel, Shal-related subfamily, member 3	0.010	Human
CAMKK1	calcium/calmodulin-dependent protein kinase kinase 1, alpha	0.010
RIMS1	regulating synaptic membrane exocytosis 1	0.010
TGFBR1	transforming growth factor, beta receptor 1	0.010
MAGEL2	MAGE-like 2	0.010
TBR1	T-box, brain, 1	0.010
OPRK1	opioid receptor, kappa 1	0.010
CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.010