IMP

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Homo sapiens

1 genes annotated in human

wnt signaling pathway involved in wound healing spreading of epidermal cells

The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis that contributes to the migration of an epidermal cell along or through a wound gap to reestablish a continuous epidermis.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "wnt signaling pathway involved in wound healing spreading of epidermal cells"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "wnt signaling pathway involved in wound healing spreading of epidermal cells" (in gray)

Name	Description	Probability	Func Analog Organism
FGF18	fibroblast growth factor 18	0.896
HES2	hairy and enhancer of split 2 (Drosophila)	0.474
WNT3	wingless-type MMTV integration site family, member 3	0.294	Human
WIF1	WNT inhibitory factor 1	0.263
ACAN	aggrecan	0.192
FOXL1	forkhead box L1	0.175
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.170
IHH	Indian hedgehog	0.164
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.130
HOXA11	homeobox A11	0.129
SHH	sonic hedgehog	0.125
LBX1	ladybird homeobox 1	0.115
WNT11	wingless-type MMTV integration site family, member 11	0.110	Human
SFRP1	secreted frizzled-related protein 1	0.109
FGF8	fibroblast growth factor 8 (androgen-induced)	0.105
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.104
EXOC3L2	exocyst complex component 3-like 2	0.094
AVPR1B	arginine vasopressin receptor 1B	0.085
AQP5	aquaporin 5	0.076
S1PR5	sphingosine-1-phosphate receptor 5	0.076
FGF3	fibroblast growth factor 3	0.075
PAX8	paired box 8	0.070
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.069
FGF4	fibroblast growth factor 4	0.069
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.065
KCNK9	potassium channel, subfamily K, member 9	0.064
SFRP5	secreted frizzled-related protein 5	0.059
HES5	hairy and enhancer of split 5 (Drosophila)	0.058
DIO3	deiodinase, iodothyronine, type III	0.056
WNT7A	wingless-type MMTV integration site family, member 7A	0.048
NPAS1	neuronal PAS domain protein 1	0.047
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.041
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.040
VSTM2L	V-set and transmembrane domain containing 2 like	0.039
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.039
HOXD13	homeobox D13	0.038
LMO1	LIM domain only 1 (rhombotin 1)	0.037
CHRD	chordin	0.037
LYPD3	LY6/PLAUR domain containing 3	0.036
DLX4	distal-less homeobox 4	0.036
JPH3	junctophilin 3	0.035
FOXD3	forkhead box D3	0.035
MIXL1	Mix1 homeobox-like 1 (Xenopus laevis)	0.034
SOX1	SRY (sex determining region Y)-box 1	0.034
KCNK15	potassium channel, subfamily K, member 15	0.034
BHLHE23	basic helix-loop-helix family, member e23	0.034
CRLF1	cytokine receptor-like factor 1	0.033
REG1B	regenerating islet-derived 1 beta	0.033
TTC22	tetratricopeptide repeat domain 22	0.033
TLX3	T-cell leukemia homeobox 3	0.033
HMX1	H6 family homeobox 1	0.033
PTH2	parathyroid hormone 2	0.032
BMP4	bone morphogenetic protein 4	0.031
HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	0.031
HOXC8	homeobox C8	0.031
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.031
EPHB3	EPH receptor B3	0.030
WNT10B	wingless-type MMTV integration site family, member 10B	0.030	Human
CDX2	caudal type homeobox 2	0.030
GUCA2A	guanylate cyclase activator 2A (guanylin)	0.030
PITX1	paired-like homeodomain 1	0.030
GDNF	glial cell derived neurotrophic factor	0.029
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A	0.028
EMX2	empty spiracles homeobox 2	0.028
HAS1	hyaluronan synthase 1	0.028
WNT5B	wingless-type MMTV integration site family, member 5B	0.028	Human
EVPL	envoplakin	0.028
BHMT	betaine--homocysteine S-methyltransferase	0.027
FZD8	frizzled homolog 8 (Drosophila)	0.027
P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2	0.027
SCARF2	scavenger receptor class F, member 2	0.027
FOXB1	forkhead box B1	0.026
PRRX2	paired related homeobox 2	0.026
C1QL1	complement component 1, q subcomponent-like 1	0.026
DLX3	distal-less homeobox 3	0.025
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.025
EPHB2	EPH receptor B2	0.024
DAPK2	death-associated protein kinase 2	0.024
IRF2BP1	interferon regulatory factor 2 binding protein 1	0.024
FOXF2	forkhead box F2	0.024
NKPD1	NTPase, KAP family P-loop domain containing 1	0.023
NKD1	naked cuticle homolog 1 (Drosophila)	0.023
POU3F1	POU class 3 homeobox 1	0.022
NXPH3	neurexophilin 3	0.022
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.022
ADRA1B	adrenergic, alpha-1B-, receptor	0.022
BARX2	BARX homeobox 2	0.022
NKX2-1	NK2 homeobox 1	0.022
KCNK12	potassium channel, subfamily K, member 12	0.021
HOXD11	homeobox D11	0.021
FAM123A	family with sequence similarity 123A	0.021
GPR20	G protein-coupled receptor 20	0.021
COL2A1	collagen, type II, alpha 1	0.020
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.020
SHOX2	short stature homeobox 2	0.020
GSC	goosecoid homeobox	0.020
ADRB3	adrenergic, beta-3-, receptor	0.020
NKX3-2	NK3 homeobox 2	0.020
OPRD1	opioid receptor, delta 1	0.020
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.020
NRTN	neurturin	0.020
BMP8A	bone morphogenetic protein 8a	0.020
ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	0.020
WNT9B	wingless-type MMTV integration site family, member 9B	0.020	Human
NEUROG2	neurogenin 2	0.020
SIX2	SIX homeobox 2	0.020
SLC16A11	solute carrier family 16, member 11 (monocarboxylic acid transporter 11)	0.019
WNT4	wingless-type MMTV integration site family, member 4	0.019	Human
TP73	tumor protein p73	0.019
EGFL6	EGF-like-domain, multiple 6	0.019
LOR	loricrin	0.019
TACR1	tachykinin receptor 1	0.018
PAX3	paired box 3	0.018
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.018
RARG	retinoic acid receptor, gamma	0.018
GGN	gametogenetin	0.018
OTP	orthopedia homeobox	0.018
CPNE9	copine family member IX	0.018
SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	0.018
GNAT1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	0.018
COL19A1	collagen, type XIX, alpha 1	0.018
COL4A6	collagen, type IV, alpha 6	0.018
DMRT3	doublesex and mab-3 related transcription factor 3	0.017
PAX2	paired box 2	0.017
MMP25	matrix metallopeptidase 25	0.017
EFNA3	ephrin-A3	0.017
NPPC	natriuretic peptide C	0.017
GP2	glycoprotein 2 (zymogen granule membrane)	0.017
RHBG	Rh family, B glycoprotein (gene/pseudogene)	0.017
DUOX1	dual oxidase 1	0.017
PLXDC1	plexin domain containing 1	0.017
CRYGN	crystallin, gamma N	0.017
HOXB8	homeobox B8	0.016
HOXD9	homeobox D9	0.016
HMX2	H6 family homeobox 2	0.016
VSX1	visual system homeobox 1	0.016
PRRG2	proline rich Gla (G-carboxyglutamic acid) 2	0.016
USH1G	Usher syndrome 1G (autosomal recessive)	0.016
SOD3	superoxide dismutase 3, extracellular	0.016
FGF19	fibroblast growth factor 19	0.016
MLNR	motilin receptor	0.015
GYLTL1B	glycosyltransferase-like 1B	0.015
KLF14	Kruppel-like factor 14	0.015
ALX4	ALX homeobox 4	0.015
GRP	gastrin-releasing peptide	0.015
IRS4	insulin receptor substrate 4	0.015
FGF10	fibroblast growth factor 10	0.015
RAX	retina and anterior neural fold homeobox	0.015
PRDM8	PR domain containing 8	0.015
HES7	hairy and enhancer of split 7 (Drosophila)	0.015
SLC30A2	solute carrier family 30 (zinc transporter), member 2	0.015
CRABP2	cellular retinoic acid binding protein 2	0.015
SCUBE3	signal peptide, CUB domain, EGF-like 3	0.015
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.015
KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.015
FOXL2	forkhead box L2	0.015
ALAS2	aminolevulinate, delta-, synthase 2	0.014
HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	0.014
SOCS1	suppressor of cytokine signaling 1	0.014
HOXD10	homeobox D10	0.014
GSTT1	glutathione S-transferase theta 1	0.014
HOXD4	homeobox D4	0.014
FAM101A	family with sequence similarity 101, member A	0.014
SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7	0.014
HOXB13	homeobox B13	0.014
EPYC	epiphycan	0.014
PRPH	peripherin	0.014
FIBCD1	fibrinogen C domain containing 1	0.014
KRTDAP	keratinocyte differentiation-associated protein	0.014
PITX2	paired-like homeodomain 2	0.014
SMPD3	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	0.014
KREMEN2	kringle containing transmembrane protein 2	0.014
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.014
NLRP6	NLR family, pyrin domain containing 6	0.014
OVOL1	ovo-like 1(Drosophila)	0.014
SLC45A1	solute carrier family 45, member 1	0.013
HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	0.013
TGM5	transglutaminase 5	0.013
SMTNL2	smoothelin-like 2	0.013
CDH22	cadherin 22, type 2	0.013
HYAL1	hyaluronoglucosaminidase 1	0.013
EYA2	eyes absent homolog 2 (Drosophila)	0.013
PTHLH	parathyroid hormone-like hormone	0.013
RHOD	ras homolog gene family, member D	0.013
DSG1	desmoglein 1	0.013
EN1	engrailed homeobox 1	0.013
SLC14A2	solute carrier family 14 (urea transporter), member 2	0.013
CXorf27	chromosome X open reading frame 27	0.013
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.013
LCE2B	late cornified envelope 2B	0.013
FEZF2	FEZ family zinc finger 2	0.013
MMP19	matrix metallopeptidase 19	0.013
WNT7B	wingless-type MMTV integration site family, member 7B	0.013	Human
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.013
COL13A1	collagen, type XIII, alpha 1	0.013
ODF3L1	outer dense fiber of sperm tails 3-like 1	0.013
CD70	CD70 molecule	0.013
HOXC12	homeobox C12	0.013
BNC1	basonuclin 1	0.013
VIPR1	vasoactive intestinal peptide receptor 1	0.013
FOLR3	folate receptor 3 (gamma)	0.012
BFSP1	beaded filament structural protein 1, filensin	0.012
IRX4	iroquois homeobox 4	0.012
RGS9BP	regulator of G protein signaling 9 binding protein	0.012
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.012
HTR2B	5-hydroxytryptamine (serotonin) receptor 2B	0.012
PI16	peptidase inhibitor 16	0.012
HOXB1	homeobox B1	0.012
ELOVL3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.012
NECAB2	N-terminal EF-hand calcium binding protein 2	0.012
MAMLD1	mastermind-like domain containing 1	0.012
NKX2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.012
TKTL1	transketolase-like 1	0.012
FZD10	frizzled homolog 10 (Drosophila)	0.012
FGD1	FYVE, RhoGEF and PH domain containing 1	0.012
CCDC48	coiled-coil domain containing 48	0.012
NPTX2	neuronal pentraxin II	0.012
STAG3	stromal antigen 3	0.012
IRF4	interferon regulatory factor 4	0.012
CDHR1	cadherin-related family member 1	0.012
BARHL1	BarH-like homeobox 1	0.012
NKX6-2	NK6 homeobox 2	0.012
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.012
SPRR2B	small proline-rich protein 2B	0.012
GALR2	galanin receptor 2	0.012
RSPO2	R-spondin 2 homolog (Xenopus laevis)	0.012
PAX7	paired box 7	0.012
HOXC5	homeobox C5	0.012
HOXC6	homeobox C6	0.012
KLHL35	kelch-like 35 (Drosophila)	0.012
TRIM67	tripartite motif containing 67	0.012
SLMO1	slowmo homolog 1 (Drosophila)	0.012
KLK10	kallikrein-related peptidase 10	0.012
DLL4	delta-like 4 (Drosophila)	0.011
GLI2	GLI family zinc finger 2	0.011
GPR161	G protein-coupled receptor 161	0.011
HOXA4	homeobox A4	0.011
COL9A3	collagen, type IX, alpha 3	0.011
OLIG2	oligodendrocyte lineage transcription factor 2	0.011
CXCL14	chemokine (C-X-C motif) ligand 14	0.011
HOXD1	homeobox D1	0.011
PALM	paralemmin	0.011
ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2	0.011
DRD4	dopamine receptor D4	0.011
PCSK9	proprotein convertase subtilisin/kexin type 9	0.011
KNDC1	kinase non-catalytic C-lobe domain (KIND) containing 1	0.011
HS3ST5	heparan sulfate (glucosamine) 3-O-sulfotransferase 5	0.011
GBX2	gastrulation brain homeobox 2	0.011
EPHA8	EPH receptor A8	0.011
BMP8B	bone morphogenetic protein 8b	0.011
KRT14	keratin 14	0.011
CDKL1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	0.011
POU4F3	POU class 4 homeobox 3	0.011
MYCL1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.011
TLX2	T-cell leukemia homeobox 2	0.011
SLC5A1	solute carrier family 5 (sodium/glucose cotransporter), member 1	0.011
SYT7	synaptotagmin VII	0.011
TG	thyroglobulin	0.011
HOXA7	homeobox A7	0.011
KLK7	kallikrein-related peptidase 7	0.011
BIK	BCL2-interacting killer (apoptosis-inducing)	0.011
CNNM4	cyclin M4	0.010
PCSK1N	proprotein convertase subtilisin/kexin type 1 inhibitor	0.010
FGF21	fibroblast growth factor 21	0.010
CST1	cystatin SN	0.010
SOSTDC1	sclerostin domain containing 1	0.010
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.010
WDR45L	WDR45-like	0.010
SIM2	single-minded homolog 2 (Drosophila)	0.010
MAG	myelin associated glycoprotein	0.010
IRX5	iroquois homeobox 5	0.010
RASL10A	RAS-like, family 10, member A	0.010
SMO	smoothened homolog (Drosophila)	0.010
LHX6	LIM homeobox 6	0.010
ADRA1D	adrenergic, alpha-1D-, receptor	0.010
CLCF1	cardiotrophin-like cytokine factor 1	0.010
PNMT	phenylethanolamine N-methyltransferase	0.010
RSPO1	R-spondin homolog (Xenopus laevis)	0.010
OAF	OAF homolog (Drosophila)	0.010
GAL	galanin prepropeptide	0.010
NOTCH3	notch 3	0.010
GJD2	gap junction protein, delta 2, 36kDa	0.010
KRT1	keratin 1	0.010
UTF1	undifferentiated embryonic cell transcription factor 1	0.010
GJA3	gap junction protein, alpha 3, 46kDa	0.010
BMP7	bone morphogenetic protein 7	0.010
A4GALT	alpha 1,4-galactosyltransferase	0.010
FBXL22	F-box and leucine-rich repeat protein 22	0.010
HR	hairless homolog (mouse)	0.010
NKX3-1	NK3 homeobox 1	0.010