IMP

Process View

Homo sapiens

3 genes annotated in human

positive regulation of icosanoid secretion

Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of icosanoid secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of icosanoid secretion" (in gray)

Name	Description	Probability	Func Analog Organism
MAP2K4	mitogen-activated protein kinase kinase 4	0.994
IL1R1	interleukin 1 receptor, type I	0.766
MAPK14	mitogen-activated protein kinase 14	0.458
KIAA1712	KIAA1712	0.314
IL1RAP	interleukin 1 receptor accessory protein	0.237
XPO7	exportin 7	0.213
IL1RN	interleukin 1 receptor antagonist	0.203
LRRK2	leucine-rich repeat kinase 2	0.198
KIAA1377	KIAA1377	0.180
C1orf93	chromosome 1 open reading frame 93	0.179
BBS10	Bardet-Biedl syndrome 10	0.111
IL8	interleukin 8	0.105
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.089	Human
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.063
CXCL3	chemokine (C-X-C motif) ligand 3	0.056
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.056
ZBTB25	zinc finger and BTB domain containing 25	0.052
CCL20	chemokine (C-C motif) ligand 20	0.051
MAPK1	mitogen-activated protein kinase 1	0.041
TRAF5	TNF receptor-associated factor 5	0.040
CXCL2	chemokine (C-X-C motif) ligand 2	0.040
MAP2K3	mitogen-activated protein kinase kinase 3	0.040
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.037
LMO4	LIM domain only 4	0.034
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.034
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.028
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.027
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.027
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.026
ATF2	activating transcription factor 2	0.026
ZC3HC1	zinc finger, C3HC-type containing 1	0.025
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.025
RGS2	regulator of G-protein signaling 2, 24kDa	0.025
HPD	4-hydroxyphenylpyruvate dioxygenase	0.024
C6	complement component 6	0.023
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.023
SBF1	SET binding factor 1	0.022
C7orf36	chromosome 7 open reading frame 36	0.021
MBTPS1	membrane-bound transcription factor peptidase, site 1	0.021
IL6	interleukin 6 (interferon, beta 2)	0.020
AQP7	aquaporin 7	0.020
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.020
AQP9	aquaporin 9	0.020
IL1R2	interleukin 1 receptor, type II	0.020
MKNK1	MAP kinase interacting serine/threonine kinase 1	0.020
LGALS4	lectin, galactoside-binding, soluble, 4	0.019
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.018
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.018
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.018
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.018
CCL4	chemokine (C-C motif) ligand 4	0.018
FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	0.018
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.017
SNRNP35	small nuclear ribonucleoprotein 35kDa (U11/U12)	0.017
RDH16	retinol dehydrogenase 16 (all-trans)	0.016
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.016
TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)	0.016
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.016
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.016
GLYAT	glycine-N-acyltransferase	0.016
ABP1	amiloride binding protein 1 (amine oxidase (copper-containing))	0.015
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.015
ADH6	alcohol dehydrogenase 6 (class V)	0.015
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.015
FRZB	frizzled-related protein	0.015
C8A	complement component 8, alpha polypeptide	0.015
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.015
STAB2	stabilin 2	0.015
CCL2	chemokine (C-C motif) ligand 2	0.014
IRAK2	interleukin-1 receptor-associated kinase 2	0.014
GH1	growth hormone 1	0.014
NLRP3	NLR family, pyrin domain containing 3	0.014
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.014
AGXT	alanine-glyoxylate aminotransferase	0.014
C8B	complement component 8, beta polypeptide	0.014
G6PC	glucose-6-phosphatase, catalytic subunit	0.014
TRAF1	TNF receptor-associated factor 1	0.014
GP2	glycoprotein 2 (zymogen granule membrane)	0.014
SOD2	superoxide dismutase 2, mitochondrial	0.014
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.013
FABP1	fatty acid binding protein 1, liver	0.013
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.013
PLG	plasminogen	0.013
GPR84	G protein-coupled receptor 84	0.013
PLAUR	plasminogen activator, urokinase receptor	0.013
MAT1A	methionine adenosyltransferase I, alpha	0.013
CXCL5	chemokine (C-X-C motif) ligand 5	0.013
CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6	0.013
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.013
PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	0.013	Human
HAL	histidine ammonia-lyase	0.013
FOXN1	forkhead box N1	0.013
GPX2	glutathione peroxidase 2 (gastrointestinal)	0.013
GPR109B	G protein-coupled receptor 109B	0.013
BCL2A1	BCL2-related protein A1	0.013
IL7R	interleukin 7 receptor	0.013
CYP4F8	cytochrome P450, family 4, subfamily F, polypeptide 8	0.013	Human
TLR2	toll-like receptor 2	0.012
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.012
KNG1	kininogen 1	0.012
CD83	CD83 molecule	0.012
OVGP1	oviductal glycoprotein 1, 120kDa	0.012
CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1	0.012	Human
ICAM1	intercellular adhesion molecule 1	0.012
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.012	Human
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.012
TREM1	triggering receptor expressed on myeloid cells 1	0.012
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.012
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.012
KYNU	kynureninase	0.012
DUSP1	dual specificity phosphatase 1	0.012
C7orf28B	chromosome 7 open reading frame 28B	0.012
LRP6	low density lipoprotein receptor-related protein 6	0.012
RIPK2	receptor-interacting serine-threonine kinase 2	0.012
MASP2	mannan-binding lectin serine peptidase 2	0.012
OTC	ornithine carbamoyltransferase	0.012
PIP	prolactin-induced protein	0.012
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.012
ALOX12	arachidonate 12-lipoxygenase	0.012
C4BPA	complement component 4 binding protein, alpha	0.012
STAU2	staufen, RNA binding protein, homolog 2 (Drosophila)	0.011
TREH	trehalase (brush-border membrane glycoprotein)	0.011
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.011
PTPRE	protein tyrosine phosphatase, receptor type, E	0.011
BHMT	betaine--homocysteine S-methyltransferase	0.011
APOC3	apolipoprotein C-III	0.011
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.011
PLEK	pleckstrin	0.011
EPHX2	epoxide hydrolase 2, cytoplasmic	0.011
HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2	0.011
TNF	tumor necrosis factor	0.011
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.011
XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.011
CHAD	chondroadherin	0.011
BMP2	bone morphogenetic protein 2	0.011
ZC3H12A	zinc finger CCCH-type containing 12A	0.011
WDR62	WD repeat domain 62	0.011
GPT	glutamic-pyruvate transaminase (alanine aminotransferase)	0.011
VIPR1	vasoactive intestinal peptide receptor 1	0.011
FETUB	fetuin B	0.011
ARG1	arginase, liver	0.011
RAB5B	RAB5B, member RAS oncogene family	0.010
MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)	0.010
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.010
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.010
SLC6A4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.010
CNGA1	cyclic nucleotide gated channel alpha 1	0.010
SSU72	SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)	0.010
BBS7	Bardet-Biedl syndrome 7	0.010
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.010
DPYS	dihydropyrimidinase	0.010
CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2	0.010
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.010
PRODH	proline dehydrogenase (oxidase) 1	0.010
DAO	D-amino-acid oxidase	0.010
DUSP16	dual specificity phosphatase 16	0.010
IL22RA1	interleukin 22 receptor, alpha 1	0.010
GFRA4	GDNF family receptor alpha 4	0.010
CES3	carboxylesterase 3	0.010