IMP

Process View

Homo sapiens

3 genes annotated in human

Multi-species View

negative regulation of monocyte differentiation

GO:0045656

Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of monocyte differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of monocyte differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
HOXB5	homeobox B5	1.000	Human
HOXA5	homeobox A5	0.991	Human
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.988
HOXB7	homeobox B7	0.955	Human
HOXA10	homeobox A10	0.948
HOXA7	homeobox A7	0.939
HOXB3	homeobox B3	0.913
HOXA4	homeobox A4	0.883	Human
HOXB6	homeobox B6	0.834	Human
HOXB9	homeobox B9	0.809
HOXA11	homeobox A11	0.698
MAX	MYC associated factor X	0.642
HOXC10	homeobox C10	0.618
HOXC6	homeobox C6	0.603	Human
HOXA2	homeobox A2	0.413
HOXA6	homeobox A6	0.385	Human
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.355
HOXC4	homeobox C4	0.281	Human
SLAMF1	signaling lymphocytic activation molecule family member 1	0.258
WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	0.240
SMAD6	SMAD family member 6	0.194
EPOR	erythropoietin receptor	0.189
HOXA3	homeobox A3	0.146
IL4R	interleukin 4 receptor	0.142
HOXC5	homeobox C5	0.133	Human
HOXB2	homeobox B2	0.120
HOXA1	homeobox A1	0.116
HOXC9	homeobox C9	0.107
ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	0.093
HOXC11	homeobox C11	0.080
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.074
HOXA13	homeobox A13	0.054
HOXC8	homeobox C8	0.050	Human
DOK1	docking protein 1, 62kDa (downstream of tyrosine kinase 1)	0.040
CRP	C-reactive protein, pentraxin-related	0.040	Human
HOXD9	homeobox D9	0.036
HOXB4	homeobox B4	0.036	Human
HOXD10	homeobox D10	0.036
SH2D1B	SH2 domain containing 1B	0.031
SH2D1A	SH2 domain containing 1A	0.031
SH3BP2	SH3-domain binding protein 2	0.031
KRT15	keratin 15	0.030
TBCD	tubulin folding cofactor D	0.028
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.028
BIN1	bridging integrator 1	0.027
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.027
HOXC13	homeobox C13	0.026
HOXB8	homeobox B8	0.024	Human
DOK3	docking protein 3	0.024
NGFR	nerve growth factor receptor	0.024
FBXW8	F-box and WD repeat domain containing 8	0.024
OTP	orthopedia homeobox	0.023
HOXD3	homeobox D3	0.022
TWIST1	twist homolog 1 (Drosophila)	0.021
SH3KBP1	SH3-domain kinase binding protein 1	0.021
FOXL1	forkhead box L1	0.020
ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.020
PDX1	pancreatic and duodenal homeobox 1	0.020
PITX2	paired-like homeodomain 2	0.020
IL4	interleukin 4	0.020
C4BPA	complement component 4 binding protein, alpha	0.019
POU2F1	POU class 2 homeobox 1	0.019
COL13A1	collagen, type XIII, alpha 1	0.018
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.018
HES1	hairy and enhancer of split 1, (Drosophila)	0.017
MSX1	msh homeobox 1	0.017
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.016
SH3GL2	SH3-domain GRB2-like 2	0.016
HOXD11	homeobox D11	0.016
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.016
SPRY2	sprouty homolog 2 (Drosophila)	0.016
BLNK	B-cell linker	0.015
FOXD1	forkhead box D1	0.015
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.015
TAL1	T-cell acute lymphocytic leukemia 1	0.015
TCF21	transcription factor 21	0.015
PAEP	progestagen-associated endometrial protein	0.014
APOC4	apolipoprotein C-IV	0.014
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	0.014
PELO	pelota homolog (Drosophila)	0.014
TERF2IP	telomeric repeat binding factor 2, interacting protein	0.013
HNF1B	HNF1 homeobox B	0.013
CLTC	clathrin, heavy chain (Hc)	0.013
SFRP5	secreted frizzled-related protein 5	0.013
HOXD8	homeobox D8	0.013	Human
SHOX2	short stature homeobox 2	0.013
MXD1	MAX dimerization protein 1	0.013
EFNA1	ephrin-A1	0.013
CDK6	cyclin-dependent kinase 6	0.013
AFP	alpha-fetoprotein	0.013
HOXB13	homeobox B13	0.012
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.012
SOCS2	suppressor of cytokine signaling 2	0.012
RRAS2	related RAS viral (r-ras) oncogene homolog 2	0.012
SIM2	single-minded homolog 2 (Drosophila)	0.012
NKX3-2	NK3 homeobox 2	0.012
EN1	engrailed homeobox 1	0.012
GATA2	GATA binding protein 2	0.012
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	0.012
ILVBL	ilvB (bacterial acetolactate synthase)-like	0.011
MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2	0.011
FMNL1	formin-like 1	0.011
KCNF1	potassium voltage-gated channel, subfamily F, member 1	0.011
DPCD	deleted in primary ciliary dyskinesia homolog (mouse)	0.011
FOXF2	forkhead box F2	0.011
FOXC1	forkhead box C1	0.011
WNT10A	wingless-type MMTV integration site family, member 10A	0.011
PRDM8	PR domain containing 8	0.011
SMAD7	SMAD family member 7	0.011
RIN3	Ras and Rab interactor 3	0.010
MEIS1	Meis homeobox 1	0.010
DLX2	distal-less homeobox 2	0.010