IMP

Process View

Homo sapiens

32 genes annotated in human

Multi-species View

regulation of plasma lipoprotein particle levels

GO:0097006

Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of plasma lipoprotein particle levels"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of plasma lipoprotein particle levels" (in gray)

Name	Description	Probability	Func Analog Organism
C1QA	complement component 1, q subcomponent, A chain	0.999	Human
ALB	albumin	0.996
APOE	apolipoprotein E	0.959
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.918
C1QC	complement component 1, q subcomponent, C chain	0.917	Human
C1QB	complement component 1, q subcomponent, B chain	0.704	Human
QKI	quaking homolog, KH domain RNA binding (mouse)	0.695
HP	haptoglobin	0.679
LDLR	low density lipoprotein receptor	0.641
APOC1	apolipoprotein C-I	0.585
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.565
APOA1	apolipoprotein A-I	0.488
SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	0.420
A2M	alpha-2-macroglobulin	0.332
AP2A1	adaptor-related protein complex 2, alpha 1 subunit	0.211
APOB	apolipoprotein B (including Ag(x) antigen)	0.210
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.129
TRAF5	TNF receptor-associated factor 5	0.127
PRKCZ	protein kinase C, zeta	0.126
APOC2	apolipoprotein C-II	0.122
ANKFY1	ankyrin repeat and FYVE domain containing 1	0.121
MAP2K3	mitogen-activated protein kinase kinase 3	0.111
RPL18A	ribosomal protein L18a	0.108
CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.095
PCSK9	proprotein convertase subtilisin/kexin type 9	0.082
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.082
TTR	transthyretin	0.076
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.069
APOA2	apolipoprotein A-II	0.061
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.058
MARCO	macrophage receptor with collagenous structure	0.054
TREM2	triggering receptor expressed on myeloid cells 2	0.054
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.052
LRRK2	leucine-rich repeat kinase 2	0.050
MTAP	methylthioadenosine phosphorylase	0.049
EPS8	epidermal growth factor receptor pathway substrate 8	0.039
WNT3A	wingless-type MMTV integration site family, member 3A	0.038
FYN	FYN oncogene related to SRC, FGR, YES	0.037
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.035
MICALL1	MICAL-like 1	0.035
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.034
CIRBP	cold inducible RNA binding protein	0.032
MDK	midkine (neurite growth-promoting factor 2)	0.031
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.031
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.031
MSR1	macrophage scavenger receptor 1	0.028	Mouse
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.027
UBASH3B	ubiquitin associated and SH3 domain containing B	0.027
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.026
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.026
AP2B1	adaptor-related protein complex 2, beta 1 subunit	0.025
LRPAP1	low density lipoprotein receptor-related protein associated protein 1	0.025
MS4A7	membrane-spanning 4-domains, subfamily A, member 7	0.025
ACP5	acid phosphatase 5, tartrate resistant	0.025
DSE	dermatan sulfate epimerase	0.025
SF1	splicing factor 1	0.025
SLAMF8	SLAM family member 8	0.024
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.024
THPO	thrombopoietin	0.024
STX12	syntaxin 12	0.023
LRP1	low density lipoprotein receptor-related protein 1	0.023
PLTP	phospholipid transfer protein	0.023
LCAT	lecithin-cholesterol acyltransferase	0.023
VLDLR	very low density lipoprotein receptor	0.023
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.022
LBP	lipopolysaccharide binding protein	0.021
IGF1R	insulin-like growth factor 1 receptor	0.021
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.020
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.020
APP	amyloid beta (A4) precursor protein	0.020
FGA	fibrinogen alpha chain	0.020
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.019
JTB	jumping translocation breakpoint	0.019
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.019
CD163	CD163 molecule	0.019
FABP4	fatty acid binding protein 4, adipocyte	0.019
HNRNPA0	heterogeneous nuclear ribonucleoprotein A0	0.018
LIPC	lipase, hepatic	0.018
AVPR2	arginine vasopressin receptor 2	0.018
MYLIP	myosin regulatory light chain interacting protein	0.018	Mouse
PTBP2	polypyrimidine tract binding protein 2	0.018
NR1H3	nuclear receptor subfamily 1, group H, member 3	0.018
MAPT	microtubule-associated protein tau	0.017
STON2	stonin 2	0.017
OSTM1	osteopetrosis associated transmembrane protein 1	0.017
LDLRAP1	low density lipoprotein receptor adaptor protein 1	0.016
ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1	0.016	Mouse
ELANE	elastase, neutrophil expressed	0.016
EHD4	EH-domain containing 4	0.016
C2	complement component 2	0.016
ABCG5	ATP-binding cassette, sub-family G (WHITE), member 5	0.015
CLEC4G	C-type lectin domain family 4, member G	0.015
GRB10	growth factor receptor-bound protein 10	0.015
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.015
IRF3	interferon regulatory factor 3	0.015
PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)	0.015
PNPLA6	patatin-like phospholipase domain containing 6	0.015
CA5A	carbonic anhydrase VA, mitochondrial	0.014
HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')	0.014
FOXO3	forkhead box O3	0.014
TLR7	toll-like receptor 7	0.014
SORBS2	sorbin and SH3 domain containing 2	0.014
PXN	paxillin	0.014
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.014
SCARB1	scavenger receptor class B, member 1	0.014
SPATA2	spermatogenesis associated 2	0.014
KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3	0.013
F11	coagulation factor XI	0.013
MTTP	microsomal triglyceride transfer protein	0.013
CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1	0.013
AMBP	alpha-1-microglobulin/bikunin precursor	0.013
MAP3K11	mitogen-activated protein kinase kinase kinase 11	0.013
C8G	complement component 8, gamma polypeptide	0.013
TMEM115	transmembrane protein 115	0.013
AGPAT2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.013
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.013
CAMP	cathelicidin antimicrobial peptide	0.013
PDCD4	programmed cell death 4 (neoplastic transformation inhibitor)	0.013
PTBP1	polypyrimidine tract binding protein 1	0.013
GGT5	gamma-glutamyltransferase 5	0.013
AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.013
NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.013
VHL	von Hippel-Lindau tumor suppressor	0.013
STK10	serine/threonine kinase 10	0.013
FAM83C	family with sequence similarity 83, member C	0.013
C4B	complement component 4B (Chido blood group)	0.013
LOXL4	lysyl oxidase-like 4	0.013
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.012
RPN2	ribophorin II	0.012
ZNF71	zinc finger protein 71	0.012
C4BPB	complement component 4 binding protein, beta	0.012
KIAA1377	KIAA1377	0.012
PRG2	proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)	0.012
CXCL9	chemokine (C-X-C motif) ligand 9	0.012
ITIH3	inter-alpha (globulin) inhibitor H3	0.012
SARDH	sarcosine dehydrogenase	0.012
SDS	serine dehydratase	0.012
SORT1	sortilin 1	0.012
MAGEB18	melanoma antigen family B, 18	0.012
RAB4B	RAB4B, member RAS oncogene family	0.012
HPD	4-hydroxyphenylpyruvate dioxygenase	0.012
CREBBP	CREB binding protein	0.012
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.012
ESRP2	epithelial splicing regulatory protein 2	0.012
CA4	carbonic anhydrase IV	0.012
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.012
CREB3L2	cAMP responsive element binding protein 3-like 2	0.012
RENBP	renin binding protein	0.012
FPR3	formyl peptide receptor 3	0.012
STAB1	stabilin 1	0.012
IVNS1ABP	influenza virus NS1A binding protein	0.012
ACAA1	acetyl-CoA acyltransferase 1	0.011
CPB2	carboxypeptidase B2 (plasma)	0.011
ITIH2	inter-alpha (globulin) inhibitor H2	0.011
VSIG4	V-set and immunoglobulin domain containing 4	0.011
HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2	0.011
DAPK3	death-associated protein kinase 3	0.011
GLYAT	glycine-N-acyltransferase	0.011
PRODH2	proline dehydrogenase (oxidase) 2	0.011
PCBP2	poly(rC) binding protein 2	0.011
ELF4	E74-like factor 4 (ets domain transcription factor)	0.011
LEP	leptin	0.011
LIPE	lipase, hormone-sensitive	0.011
GPNMB	glycoprotein (transmembrane) nmb	0.011
ACSL1	acyl-CoA synthetase long-chain family member 1	0.011
SPP1	secreted phosphoprotein 1	0.011
CHIT1	chitinase 1 (chitotriosidase)	0.011
TOM1	target of myb1 (chicken)	0.011
NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	0.011
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.011
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.011
CANX	calnexin	0.011
SSR4	signal sequence receptor, delta (translocon-associated protein delta)	0.011
LILRB5	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	0.011
AFP	alpha-fetoprotein	0.011
AGXT	alanine-glyoxylate aminotransferase	0.011
MRC1	mannose receptor, C type 1	0.011
MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)	0.011
VTN	vitronectin	0.011
OR2T6	olfactory receptor, family 2, subfamily T, member 6	0.011
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.011
CD68	CD68 molecule	0.011
BHMT	betaine--homocysteine S-methyltransferase	0.010
HABP2	hyaluronan binding protein 2	0.010
PRTN3	proteinase 3	0.010
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.010
TRIP10	thyroid hormone receptor interactor 10	0.010
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.010
RXRB	retinoid X receptor, beta	0.010
ZBTB39	zinc finger and BTB domain containing 39	0.010
APOC4	apolipoprotein C-IV	0.010
PC	pyruvate carboxylase	0.010
CDC42EP2	CDC42 effector protein (Rho GTPase binding) 2	0.010
HIPK3	homeodomain interacting protein kinase 3	0.010
MGAT1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	0.010
SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	0.010
ADORA3	adenosine A3 receptor	0.010