IMP
Process View
pancreatic a cell differentiation
The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "pancreatic a cell differentiation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| MAFA | v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) | 1.000 | ||
| CSNK1E | casein kinase 1, epsilon | 0.997 | ||
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.994 | ||
| NKX2-2 | NK2 homeobox 2 | 0.928 | Mouse | |
| BBS10 | Bardet-Biedl syndrome 10 | 0.837 | ||
| PDX1 | pancreatic and duodenal homeobox 1 | 0.755 | ||
| NEUROD1 | neurogenic differentiation 1 | 0.464 | Mouse | |
| PAX6 | paired box 6 | 0.443 | ||
| IPO13 | importin 13 | 0.354 | ||
| ISL1 | ISL LIM homeobox 1 | 0.289 | Zebrafish | |
| MYT1 | myelin transcription factor 1 | 0.226 | ||
| ZNF331 | zinc finger protein 331 | 0.202 | ||
| SCGN | secretagogin, EF-hand calcium binding protein | 0.173 | ||
| GCG | glucagon | 0.111 | ||
| HNF1A | HNF1 homeobox A | 0.105 | ||
| LHX2 | LIM homeobox 2 | 0.097 | ||
| SLC2A2 | solute carrier family 2 (facilitated glucose transporter), member 2 | 0.088 | ||
| MCC | mutated in colorectal cancers | 0.079 | ||
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.079 | ||
| FAM110A | family with sequence similarity 110, member A | 0.071 | ||
| FAM110C | family with sequence similarity 110, member C | 0.070 | ||
| SOX2 | SRY (sex determining region Y)-box 2 | 0.070 | ||
| INSM1 | insulinoma-associated 1 | 0.068 | Mouse | |
| SYT13 | synaptotagmin XIII | 0.068 | ||
| SIX3 | SIX homeobox 3 | 0.066 | ||
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) | 0.058 | ||
| PYY | peptide YY | 0.053 | ||
| CHGA | chromogranin A (parathyroid secretory protein 1) | 0.052 | ||
| ABCC8 | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 | 0.051 | ||
| PROX1 | prospero homeobox 1 | 0.048 | ||
| FEV | FEV (ETS oncogene family) | 0.047 | ||
| IER2 | immediate early response 2 | 0.045 | ||
| ARX | aristaless related homeobox | 0.045 | Zebrafish | |
| PAX4 | paired box 4 | 0.044 | Human | |
| DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.044 | ||
| SST | somatostatin | 0.043 | ||
| NEUROG3 | neurogenin 3 | 0.042 | ||
| HMGCL | 3-hydroxymethyl-3-methylglutaryl-CoA lyase | 0.041 | ||
| CDX2 | caudal type homeobox 2 | 0.040 | ||
| RAX | retina and anterior neural fold homeobox | 0.039 | ||
| PCSK2 | proprotein convertase subtilisin/kexin type 2 | 0.036 | ||
| FOXA2 | forkhead box A2 | 0.034 | ||
| FOXA1 | forkhead box A1 | 0.033 | ||
| ZIC1 | Zic family member 1 (odd-paired homolog, Drosophila) | 0.033 | ||
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.032 | ||
| IAPP | islet amyloid polypeptide | 0.032 | ||
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.031 | ||
| POU3F4 | POU class 3 homeobox 4 | 0.031 | ||
| HOXD13 | homeobox D13 | 0.030 | ||
| HOXB13 | homeobox B13 | 0.030 | ||
| MNX1 | motor neuron and pancreas homeobox 1 | 0.029 | ||
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.028 | ||
| DCX | doublecortin | 0.028 | ||
| CRYBA2 | crystallin, beta A2 | 0.027 | ||
| ZIC3 | Zic family member 3 (odd-paired homolog, Drosophila) | 0.026 | ||
| ELAVL3 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 0.026 | ||
| AXIN1 | axin 1 | 0.024 | ||
| SOX11 | SRY (sex determining region Y)-box 11 | 0.023 | ||
| ELAVL2 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) | 0.022 | ||
| RORB | RAR-related orphan receptor B | 0.020 | ||
| NOL4 | nucleolar protein 4 | 0.020 | ||
| POU3F2 | POU class 3 homeobox 2 | 0.020 | ||
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | 0.020 | ||
| ADCYAP1 | adenylate cyclase activating polypeptide 1 (pituitary) | 0.020 | ||
| CBLN1 | cerebellin 1 precursor | 0.019 | ||
| ASCL1 | achaete-scute complex homolog 1 (Drosophila) | 0.019 | ||
| GJD2 | gap junction protein, delta 2, 36kDa | 0.018 | ||
| EN1 | engrailed homeobox 1 | 0.017 | ||
| HOXD11 | homeobox D11 | 0.017 | ||
| HOXD1 | homeobox D1 | 0.017 | ||
| SFRP5 | secreted frizzled-related protein 5 | 0.016 | ||
| GPR6 | G protein-coupled receptor 6 | 0.016 | ||
| PER1 | period homolog 1 (Drosophila) | 0.016 | ||
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.016 | ||
| MSX1 | msh homeobox 1 | 0.016 | ||
| MTA2 | metastasis associated 1 family, member 2 | 0.016 | ||
| NKX3-2 | NK3 homeobox 2 | 0.015 | ||
| FOXG1 | forkhead box G1 | 0.015 | ||
| SCG5 | secretogranin V (7B2 protein) | 0.015 | ||
| CADM4 | cell adhesion molecule 4 | 0.015 | ||
| KLF13 | Kruppel-like factor 13 | 0.015 | ||
| FHL1 | four and a half LIM domains 1 | 0.015 | ||
| SLC17A6 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 | 0.015 | ||
| MAGEA12 | melanoma antigen family A, 12 | 0.015 | ||
| EN2 | engrailed homeobox 2 | 0.015 | ||
| PCDH8 | protocadherin 8 | 0.014 | ||
| KCNJ3 | potassium inwardly-rectifying channel, subfamily J, member 3 | 0.014 | ||
| SALL1 | sal-like 1 (Drosophila) | 0.014 | ||
| FOXO1 | forkhead box O1 | 0.014 | ||
| FOXD1 | forkhead box D1 | 0.014 | ||
| HTR2C | 5-hydroxytryptamine (serotonin) receptor 2C | 0.014 | ||
| PPY | pancreatic polypeptide | 0.013 | ||
| OLIG2 | oligodendrocyte lineage transcription factor 2 | 0.013 | ||
| PRDM13 | PR domain containing 13 | 0.013 | ||
| ONECUT1 | one cut homeobox 1 | 0.013 | ||
| SCG2 | secretogranin II | 0.013 | ||
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | 0.013 | ||
| ZNF579 | zinc finger protein 579 | 0.013 | ||
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 | 0.012 | ||
| FAM5C | family with sequence similarity 5, member C | 0.012 | ||
| BCL2 | B-cell CLL/lymphoma 2 | 0.012 | ||
| PITX2 | paired-like homeodomain 2 | 0.012 | ||
| SNAP91 | synaptosomal-associated protein, 91kDa homolog (mouse) | 0.012 | ||
| SI | sucrase-isomaltase (alpha-glucosidase) | 0.012 | ||
| NRXN1 | neurexin 1 | 0.012 | ||
| FOXB1 | forkhead box B1 | 0.011 | ||
| FABP7 | fatty acid binding protein 7, brain | 0.011 | ||
| NXPH1 | neurexophilin 1 | 0.011 | ||
| USH1C | Usher syndrome 1C (autosomal recessive, severe) | 0.011 | ||
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) | 0.011 | ||
| OCLN | occludin | 0.011 | ||
| POU4F2 | POU class 4 homeobox 2 | 0.011 | ||
| ELAVL4 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) | 0.011 | ||
| FOXF2 | forkhead box F2 | 0.011 | ||
| NKX6-1 | NK6 homeobox 1 | 0.011 | Zebrafish | |
| SIM2 | single-minded homolog 2 (Drosophila) | 0.011 | ||
| CDKN2B | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 0.010 | ||
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.010 | ||
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) | 0.010 | ||
| POU4F1 | POU class 4 homeobox 1 | 0.010 | ||
| HOXD10 | homeobox D10 | 0.010 | ||
| FOXE1 | forkhead box E1 (thyroid transcription factor 2) | 0.010 | ||
| CRH | corticotropin releasing hormone | 0.010 | ||
| TYRP1 | tyrosinase-related protein 1 | 0.010 |