IMP

Process View

Homo sapiens

2 genes annotated in human

positive regulation of heart growth

Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of heart growth"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of heart growth" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	1.000	Mouse
FGF1	fibroblast growth factor 1 (acidic)	1.000	Human
FGF10	fibroblast growth factor 10	0.997	Human
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.937
CDK2	cyclin-dependent kinase 2	0.814
UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.796
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.778
MAML1	mastermind-like 1 (Drosophila)	0.745
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.723
FRS2	fibroblast growth factor receptor substrate 2	0.494
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.486
FGF7	fibroblast growth factor 7	0.459	Human
CCNE1	cyclin E1	0.448
JAG1	jagged 1	0.397
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.360
FGFR1	fibroblast growth factor receptor 1	0.311	Mouse
EP300	E1A binding protein p300	0.266
CCNA2	cyclin A2	0.236
CCNB1	cyclin B1	0.215	Rat
HDAC4	histone deacetylase 4	0.177
CREBBP	CREB binding protein	0.166
CKS2	CDC28 protein kinase regulatory subunit 2	0.154
ATXN1L	ataxin 1-like	0.149
SIRT1	sirtuin 1	0.131
FGFR3	fibroblast growth factor receptor 3	0.131
TBX5	T-box 5	0.104	Mouse
PLCG1	phospholipase C, gamma 1	0.103
DLG2	discs, large homolog 2 (Drosophila)	0.102
NOTCH3	notch 3	0.083
FGF2	fibroblast growth factor 2 (basic)	0.075
KAT2B	K(lysine) acetyltransferase 2B	0.061
MEF2A	myocyte enhancer factor 2A	0.061
ESR1	estrogen receptor 1	0.057
CDK1	cyclin-dependent kinase 1	0.057	Rat
HDAC9	histone deacetylase 9	0.057
KLF13	Kruppel-like factor 13	0.053
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.052
HNF4A	hepatocyte nuclear factor 4, alpha	0.051
NCOA1	nuclear receptor coactivator 1	0.050
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.046
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.046
TRO	trophinin	0.044
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.043
XIAP	X-linked inhibitor of apoptosis	0.041
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.040
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.039
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.033
CCNB2	cyclin B2	0.033
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.028
APP	amyloid beta (A4) precursor protein	0.025
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.025
NOSTRIN	nitric oxide synthase trafficker	0.024
CTNNBL1	catenin, beta like 1	0.023
DLL1	delta-like 1 (Drosophila)	0.021
QKI	quaking homolog, KH domain RNA binding (mouse)	0.020
TMF1	TATA element modulatory factor 1	0.020
GATA4	GATA binding protein 4	0.020	Mouse
SKP2	S-phase kinase-associated protein 2 (p45)	0.019
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.019
GDA	guanine deaminase	0.019
CIR1	corepressor interacting with RBPJ, 1	0.018
RBPMS	RNA binding protein with multiple splicing	0.017
AR	androgen receptor	0.017
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.016
CTGF	connective tissue growth factor	0.016
DLG4	discs, large homolog 4 (Drosophila)	0.016
CCNB1IP1	cyclin B1 interacting protein 1, E3 ubiquitin protein ligase	0.016
ANKS1A	ankyrin repeat and sterile alpha motif domain containing 1A	0.016
NOTCH2	notch 2	0.016
SART1	squamous cell carcinoma antigen recognized by T cells	0.016
GATA5	GATA binding protein 5	0.015
ZNF205	zinc finger protein 205	0.015
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.015
CELF2	CUGBP, Elav-like family member 2	0.014
SYK	spleen tyrosine kinase	0.014
NCOR1	nuclear receptor corepressor 1	0.014
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.014
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.014
TNS4	tensin 4	0.014
KAL1	Kallmann syndrome 1 sequence	0.014
CTBP2	C-terminal binding protein 2	0.014
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.013
JAG2	jagged 2	0.013
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.013
EEF2K	eukaryotic elongation factor-2 kinase	0.013
HTT	huntingtin	0.013
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.012
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.012	Rat
NCOA3	nuclear receptor coactivator 3	0.012
ZEB2	zinc finger E-box binding homeobox 2	0.012
DLG3	discs, large homolog 3 (Drosophila)	0.012
TAOK1	TAO kinase 1	0.011
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.011
TCF4	transcription factor 4	0.011
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.011
NLGN1	neuroligin 1	0.011
SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	0.011
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.010
SPTB	spectrin, beta, erythrocytic	0.010