IMP

Process View

Homo sapiens

1 genes annotated in human

dendritic cell antigen processing and presentation

The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dendritic cell antigen processing and presentation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dendritic cell antigen processing and presentation" (in gray)

Name	Description	Probability	Func Analog Organism
HLA-DRA	major histocompatibility complex, class II, DR alpha	1.000
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	1.000
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	1.000
HLA-DMA	major histocompatibility complex, class II, DM alpha	1.000
HLA-DMB	major histocompatibility complex, class II, DM beta	1.000
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	1.000
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.999
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.999
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.996
CXCR4	chemokine (C-X-C motif) receptor 4	0.995
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.868
RIPK2	receptor-interacting serine-threonine kinase 2	0.297
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.284
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.259
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.194
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.184
CD37	CD37 molecule	0.173
CXCL9	chemokine (C-X-C motif) ligand 9	0.157
HLA-DQA2	major histocompatibility complex, class II, DQ alpha 2	0.155
CCR7	chemokine (C-C motif) receptor 7	0.147	Mouse
CXCL13	chemokine (C-X-C motif) ligand 13	0.146
TGFB1	transforming growth factor, beta 1	0.143
CD40	CD40 molecule, TNF receptor superfamily member 5	0.123
FN1	fibronectin 1	0.061
IL2RG	interleukin 2 receptor, gamma	0.061
SLIT3	slit homolog 3 (Drosophila)	0.058
CCR5	chemokine (C-C motif) receptor 5	0.056
AEBP1	AE binding protein 1	0.056
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.052
FAIM3	Fas apoptotic inhibitory molecule 3	0.052
IL21R	interleukin 21 receptor	0.050
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.045
PCOLCE	procollagen C-endopeptidase enhancer	0.044
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.043
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.042
HLA-DQB2	major histocompatibility complex, class II, DQ beta 2	0.040
LY9	lymphocyte antigen 9	0.039
CCL22	chemokine (C-C motif) ligand 22	0.034
DARC	Duffy blood group, chemokine receptor	0.033
CD52	CD52 molecule	0.032
CD72	CD72 molecule	0.031
LAPTM5	lysosomal protein transmembrane 5	0.031
COL16A1	collagen, type XVI, alpha 1	0.030
IRF8	interferon regulatory factor 8	0.030
ENG	endoglin	0.027
DPT	dermatopontin	0.026
SFRP4	secreted frizzled-related protein 4	0.025
CD83	CD83 molecule	0.025
CCL19	chemokine (C-C motif) ligand 19	0.024	Mouse
CECR1	cat eye syndrome chromosome region, candidate 1	0.024
FBLN2	fibulin 2	0.023
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.022
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.022
SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	0.021
CLEC10A	C-type lectin domain family 10, member A	0.021
PLEK	pleckstrin	0.020
PRELP	proline/arginine-rich end leucine-rich repeat protein	0.019
CD27	CD27 molecule	0.018
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.018
IGL@	immunoglobulin lambda locus	0.018
CD7	CD7 molecule	0.018
THY1	Thy-1 cell surface antigen	0.018
CCL2	chemokine (C-C motif) ligand 2	0.017
CCL5	chemokine (C-C motif) ligand 5	0.017
TPSB2	tryptase beta 2 (gene/pseudogene)	0.016
TLN1	talin 1	0.016
TPSAB1	tryptase alpha/beta 1	0.016
THBS4	thrombospondin 4	0.016	Human
CD1C	CD1c molecule	0.016
C3	complement component 3	0.016
PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	0.016
MXRA5	matrix-remodelling associated 5	0.016
RARRES2	retinoic acid receptor responder (tazarotene induced) 2	0.016
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.015
GPR183	G protein-coupled receptor 183	0.015
SELP	selectin P (granule membrane protein 140kDa, antigen CD62)	0.015
C1S	complement component 1, s subcomponent	0.014
C1QA	complement component 1, q subcomponent, A chain	0.014
FMOD	fibromodulin	0.014
RUNX3	runt-related transcription factor 3	0.014
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.014
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.014
CD86	CD86 molecule	0.014
C4B	complement component 4B (Chido blood group)	0.014
EBI3	Epstein-Barr virus induced 3	0.014
C1QB	complement component 1, q subcomponent, B chain	0.013
ITGB7	integrin, beta 7	0.013
CD79A	CD79a molecule, immunoglobulin-associated alpha	0.013
LY86	lymphocyte antigen 86	0.013
CCL8	chemokine (C-C motif) ligand 8	0.013
COMP	cartilage oligomeric matrix protein	0.013	Human
RGS1	regulator of G-protein signaling 1	0.013
COL1A1	collagen, type I, alpha 1	0.013
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.013
FILIP1L	filamin A interacting protein 1-like	0.012
CTSH	cathepsin H	0.012
GZMK	granzyme K (granzyme 3; tryptase II)	0.012
MSC	musculin	0.012
BTN2A2	butyrophilin, subfamily 2, member A2	0.012
CXCR3	chemokine (C-X-C motif) receptor 3	0.012
LTF	lactotransferrin	0.012
SPHK1	sphingosine kinase 1	0.012
PLXDC1	plexin domain containing 1	0.012
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.011
ACP5	acid phosphatase 5, tartrate resistant	0.011
CCR6	chemokine (C-C motif) receptor 6	0.011
CNN1	calponin 1, basic, smooth muscle	0.011
P2RY10	purinergic receptor P2Y, G-protein coupled, 10	0.011
CH25H	cholesterol 25-hydroxylase	0.011
CD3D	CD3d molecule, delta (CD3-TCR complex)	0.011
CXCR5	chemokine (C-X-C motif) receptor 5	0.011
MEOX1	mesenchyme homeobox 1	0.010
GGT5	gamma-glutamyltransferase 5	0.010
GPR18	G protein-coupled receptor 18	0.010
IL2RB	interleukin 2 receptor, beta	0.010
C7	complement component 7	0.010
IL7R	interleukin 7 receptor	0.010
MXRA8	matrix-remodelling associated 8	0.010
TRAF1	TNF receptor-associated factor 1	0.010
ANGPTL2	angiopoietin-like 2	0.010
CXCL12	chemokine (C-X-C motif) ligand 12	0.010
RNASE6	ribonuclease, RNase A family, k6	0.010