IMP

Process View

Homo sapiens

14 genes annotated in human

arachidonic acid metabolic process

GO:0019369

The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "arachidonic acid metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "arachidonic acid metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
MAPK1	mitogen-activated protein kinase 1	0.998
DHCR7	7-dehydrocholesterol reductase	0.998
CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6	0.996
COTL1	coactosin-like 1 (Dictyostelium)	0.987
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.986	Human
DUSP1	dual specificity phosphatase 1	0.970
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.887
MAPK14	mitogen-activated protein kinase 14	0.843
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.724	Human
FADS2	fatty acid desaturase 2	0.637
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.520	Human Rat
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.473
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.459
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.406	Human
CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	0.316	Human
DUSP3	dual specificity phosphatase 3	0.246
C8B	complement component 8, beta polypeptide	0.207
IL8	interleukin 8	0.169
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.128	Human
MAP2K1	mitogen-activated protein kinase kinase 1	0.127
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.125
RPS6KA4	ribosomal protein S6 kinase, 90kDa, polypeptide 4	0.110
GLYAT	glycine-N-acyltransferase	0.105
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.101
ALOX12B	arachidonate 12-lipoxygenase, 12R type	0.101
PEA15	phosphoprotein enriched in astrocytes 15	0.097
ADH6	alcohol dehydrogenase 6 (class V)	0.091
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.085
KNG1	kininogen 1	0.081
CXCL2	chemokine (C-X-C motif) ligand 2	0.080
OTC	ornithine carbamoyltransferase	0.080
ALOXE3	arachidonate lipoxygenase 3	0.080
MAT1A	methionine adenosyltransferase I, alpha	0.077
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.069
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.067
F9	coagulation factor IX	0.066
C8A	complement component 8, alpha polypeptide	0.066
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.066	Human
DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.065
CXCL3	chemokine (C-X-C motif) ligand 3	0.058
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.058
NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.057
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.056
DAO	D-amino-acid oxidase	0.056
HRG	histidine-rich glycoprotein	0.055
KRT5	keratin 5	0.055
FETUB	fetuin B	0.052
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.051
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.050	Human
BHMT	betaine--homocysteine S-methyltransferase	0.048
AGXT2	alanine--glyoxylate aminotransferase 2	0.048
SCD	stearoyl-CoA desaturase (delta-9-desaturase)	0.047
CFHR4	complement factor H-related 4	0.046
DAPK1	death-associated protein kinase 1	0.045
HAL	histidine ammonia-lyase	0.044
PLAUR	plasminogen activator, urokinase receptor	0.044
LAMC3	laminin, gamma 3	0.043
CRP	C-reactive protein, pentraxin-related	0.043
ELK1	ELK1, member of ETS oncogene family	0.042
ALDOB	aldolase B, fructose-bisphosphate	0.041
IL1B	interleukin 1, beta	0.040
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.039
SLC28A1	solute carrier family 28 (sodium-coupled nucleoside transporter), member 1	0.038
C6	complement component 6	0.035
AADAC	arylacetamide deacetylase (esterase)	0.035
RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	0.035
MASP2	mannan-binding lectin serine peptidase 2	0.034
PLG	plasminogen	0.034
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.033
ZNF219	zinc finger protein 219	0.033
G6PC	glucose-6-phosphatase, catalytic subunit	0.032
NAMPT	nicotinamide phosphoribosyltransferase	0.032
SCAND1	SCAN domain containing 1	0.032
FMO4	flavin containing monooxygenase 4	0.031
DPYS	dihydropyrimidinase	0.031
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.031
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.030
GPLD1	glycosylphosphatidylinositol specific phospholipase D1	0.030
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	0.030	Human Mouse
FABP1	fatty acid binding protein 1, liver	0.029
GSTA3	glutathione S-transferase alpha 3	0.029
HAO1	hydroxyacid oxidase (glycolate oxidase) 1	0.028
ALOX5AP	arachidonate 5-lipoxygenase-activating protein	0.028
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	0.027	Human
TGM1	transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)	0.027
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.025
SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	0.025
IER3	immediate early response 3	0.024
CTSB	cathepsin B	0.024
GNA13	guanine nucleotide binding protein (G protein), alpha 13	0.023
RDH16	retinol dehydrogenase 16 (all-trans)	0.023
KLK13	kallikrein-related peptidase 13	0.023
LPA	lipoprotein, Lp(a)	0.022
XDH	xanthine dehydrogenase	0.022
PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.022	Rat
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.021
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.021
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.021
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.021
NR1I3	nuclear receptor subfamily 1, group I, member 3	0.020
MAP2K3	mitogen-activated protein kinase kinase 3	0.020
PNKD	paroxysmal nonkinesigenic dyskinesia	0.020
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.020
MTTP	microsomal triglyceride transfer protein	0.020
CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1	0.020	Human
HPD	4-hydroxyphenylpyruvate dioxygenase	0.019
ARG1	arginase, liver	0.019
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.019
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.019
C9	complement component 9	0.019
F13B	coagulation factor XIII, B polypeptide	0.018
HABP2	hyaluronan binding protein 2	0.018
DUSP6	dual specificity phosphatase 6	0.018
RGS2	regulator of G-protein signaling 2, 24kDa	0.017
IL1RN	interleukin 1 receptor antagonist	0.016
ACRV1	acrosomal vesicle protein 1	0.016
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.016
TAT	tyrosine aminotransferase	0.016
GYS2	glycogen synthase 2 (liver)	0.015
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.015
ADRA1A	adrenergic, alpha-1A-, receptor	0.015
MKNK1	MAP kinase interacting serine/threonine kinase 1	0.015
BARX1	BARX homeobox 1	0.015
PAH	phenylalanine hydroxylase	0.015
CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6	0.015	Human Rat
HPX	hemopexin	0.015
CA5A	carbonic anhydrase VA, mitochondrial	0.015
APOC3	apolipoprotein C-III	0.015
GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	0.015
SULT1E1	sulfotransferase family 1E, estrogen-preferring, member 1	0.015
APCS	amyloid P component, serum	0.015
ITIH4	inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)	0.015
PON1	paraoxonase 1	0.014
TTPA	tocopherol (alpha) transfer protein	0.014
CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1	0.014
AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.014
MAP2K6	mitogen-activated protein kinase kinase 6	0.014
LECT2	leukocyte cell-derived chemotaxin 2	0.014
APOF	apolipoprotein F	0.014
PTX3	pentraxin 3, long	0.014
PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.013
THBS1	thrombospondin 1	0.013
AGXT	alanine-glyoxylate aminotransferase	0.013
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.013
CNGA1	cyclic nucleotide gated channel alpha 1	0.013
TTYH3	tweety homolog 3 (Drosophila)	0.013
MEP1B	meprin A, beta	0.013
HGD	homogentisate 1,2-dioxygenase	0.013
CCL16	chemokine (C-C motif) ligand 16	0.013
ALOX15B	arachidonate 15-lipoxygenase, type B	0.012
C4BPA	complement component 4 binding protein, alpha	0.012
TUBB6	tubulin, beta 6	0.012
VNN1	vanin 1	0.012
DIO1	deiodinase, iodothyronine, type I	0.012
RIT1	Ras-like without CAAX 1	0.012
CIDEB	cell death-inducing DFFA-like effector b	0.012
PNLIPRP1	pancreatic lipase-related protein 1	0.012
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.012
APOC4	apolipoprotein C-IV	0.012
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.012
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.012
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.012
A1CF	APOBEC1 complementation factor	0.012
F11	coagulation factor XI	0.012
CDA	cytidine deaminase	0.012
CYP2A7	cytochrome P450, family 2, subfamily A, polypeptide 7	0.011	Human
THBD	thrombomodulin	0.011
PISD	phosphatidylserine decarboxylase	0.011
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.011
CYP2F1	cytochrome P450, family 2, subfamily F, polypeptide 1	0.011	Human
CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1	0.011	Human
PIK3C2G	phosphoinositide-3-kinase, class 2, gamma polypeptide	0.011
FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	0.011
MUC3A	mucin 3A, cell surface associated	0.011
TG	thyroglobulin	0.011
PIPOX	pipecolic acid oxidase	0.011
SPP2	secreted phosphoprotein 2, 24kDa	0.011
MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	0.010
AFM	afamin	0.010
PTAFR	platelet-activating factor receptor	0.010
GAB2	GRB2-associated binding protein 2	0.010
MKNK2	MAP kinase interacting serine/threonine kinase 2	0.010
UGT2B15	UDP glucuronosyltransferase 2 family, polypeptide B15	0.010
RORC	RAR-related orphan receptor C	0.010
LY6G6C	lymphocyte antigen 6 complex, locus G6C	0.010