IMP

Process View

Homo sapiens

1 genes annotated in human

Multi-species View

regulation of t helper 1 cell activation

GO:2000517

Any process that modulates the frequency, rate or extent of T-helper 1 cell activation.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of t helper 1 cell activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of t helper 1 cell activation" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	1.000
CCL4	chemokine (C-C motif) ligand 4	0.982	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.953
CCL8	chemokine (C-C motif) ligand 8	0.920	Human
CCL2	chemokine (C-C motif) ligand 2	0.876	Human
CCL13	chemokine (C-C motif) ligand 13	0.811	Human
DPP4	dipeptidyl-peptidase 4	0.806
IDE	insulin-degrading enzyme	0.699
IL1B	interleukin 1, beta	0.690
CCL5	chemokine (C-C motif) ligand 5	0.665	Human
CCL22	chemokine (C-C motif) ligand 22	0.663	Human
IL8	interleukin 8	0.654
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.650
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.623	Human
CCR7	chemokine (C-C motif) receptor 7	0.536
CXCL2	chemokine (C-X-C motif) ligand 2	0.501
CXCL11	chemokine (C-X-C motif) ligand 11	0.483
CXCL10	chemokine (C-X-C motif) ligand 10	0.469
CCL3	chemokine (C-C motif) ligand 3	0.446	Human
IL6	interleukin 6 (interferon, beta 2)	0.418
CXCL13	chemokine (C-X-C motif) ligand 13	0.417
CXCL3	chemokine (C-X-C motif) ligand 3	0.353
IFNG	interferon, gamma	0.313
CCR1	chemokine (C-C motif) receptor 1	0.274
CCL19	chemokine (C-C motif) ligand 19	0.272	Human
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.230
CCR4	chemokine (C-C motif) receptor 4	0.215
CCL11	chemokine (C-C motif) ligand 11	0.197	Human
GNLY	granulysin	0.173
CD83	CD83 molecule	0.161
IL2RB	interleukin 2 receptor, beta	0.137
VCAM1	vascular cell adhesion molecule 1	0.118
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.105
CCL7	chemokine (C-C motif) ligand 7	0.105	Human
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.103
TNF	tumor necrosis factor	0.102
IL10	interleukin 10	0.102
CXCL5	chemokine (C-X-C motif) ligand 5	0.092
SELE	selectin E	0.092
RGS1	regulator of G-protein signaling 1	0.086
CCL21	chemokine (C-C motif) ligand 21	0.079
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.078
CH25H	cholesterol 25-hydroxylase	0.058
IL7R	interleukin 7 receptor	0.057
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.055
CCL20	chemokine (C-C motif) ligand 20	0.054	Human
CCL17	chemokine (C-C motif) ligand 17	0.052	Human
UBD	ubiquitin D	0.051
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.044
DARC	Duffy blood group, chemokine receptor	0.042
EBI3	Epstein-Barr virus induced 3	0.042
FPR3	formyl peptide receptor 3	0.041
LAMP3	lysosomal-associated membrane protein 3	0.040
CD160	CD160 molecule	0.038
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.038
CXCR6	chemokine (C-X-C motif) receptor 6	0.038
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.037
CD69	CD69 molecule	0.036
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.036
C1QA	complement component 1, q subcomponent, A chain	0.035
SLAMF7	SLAM family member 7	0.034
IL18RAP	interleukin 18 receptor accessory protein	0.032
ICAM1	intercellular adhesion molecule 1	0.031
CTSW	cathepsin W	0.030
ARRB1	arrestin, beta 1	0.029
IL21R	interleukin 21 receptor	0.029
STAT4	signal transducer and activator of transcription 4	0.028
IL32	interleukin 32	0.027
XCL1	chemokine (C motif) ligand 1	0.027
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.026
CXCR3	chemokine (C-X-C motif) receptor 3	0.026
ADAMDEC1	ADAM-like, decysin 1	0.026
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.026
IL2RG	interleukin 2 receptor, gamma	0.025
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.024
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.022
INHBA	inhibin, beta A	0.022
IDO1	indoleamine 2,3-dioxygenase 1	0.021
CCR3	chemokine (C-C motif) receptor 3	0.021
IRF4	interferon regulatory factor 4	0.020
SLAMF8	SLAM family member 8	0.020
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.019
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.019
CCL1	chemokine (C-C motif) ligand 1	0.019	Human
MSC	musculin	0.018
ICOS	inducible T-cell co-stimulator	0.018
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.017
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.017
DPT	dermatopontin	0.016
IL1A	interleukin 1, alpha	0.016
BATF	basic leucine zipper transcription factor, ATF-like	0.016
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.015
PDPN	podoplanin	0.015
XCL2	chemokine (C motif) ligand 2	0.015	Human
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.015
RGS16	regulator of G-protein signaling 16	0.014
CCL23	chemokine (C-C motif) ligand 23	0.014	Human
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.014
NKG7	natural killer cell group 7 sequence	0.014
CD209	CD209 molecule	0.014
CD40	CD40 molecule, TNF receptor superfamily member 5	0.014
IL13	interleukin 13	0.013
PI3	peptidase inhibitor 3, skin-derived	0.013
IL2RA	interleukin 2 receptor, alpha	0.013
IL11	interleukin 11	0.013
CCBP2	chemokine binding protein 2	0.012
CD80	CD80 molecule	0.012
DNASE1L3	deoxyribonuclease I-like 3	0.012
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.012
CCRL2	chemokine (C-C motif) receptor-like 2	0.012
CD1B	CD1b molecule	0.011
SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	0.011
PLAU	plasminogen activator, urokinase	0.011
RARRES1	retinoic acid receptor responder (tazarotene induced) 1	0.011
CHIT1	chitinase 1 (chitotriosidase)	0.011
CLEC10A	C-type lectin domain family 10, member A	0.011
LAG3	lymphocyte-activation gene 3	0.011
CD2	CD2 molecule	0.011
TNFRSF4	tumor necrosis factor receptor superfamily, member 4	0.011
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.011
BCL2A1	BCL2-related protein A1	0.011
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.010
BDKRB1	bradykinin receptor B1	0.010
IL1R2	interleukin 1 receptor, type II	0.010