IMP
Process View
heart valve formation
The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "heart valve formation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| JAG1 | jagged 1 | 0.998 | ||
| SKIL | SKI-like oncogene | 0.992 | ||
| NOTCH1 | notch 1 | 0.988 | ||
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.938 | ||
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.762 | ||
| SMAD3 | SMAD family member 3 | 0.738 | ||
| SETD8 | SET domain containing (lysine methyltransferase) 8 | 0.702 | ||
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.437 | ||
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.406 | ||
| DLL1 | delta-like 1 (Drosophila) | 0.374 | ||
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.337 | ||
| SMAD2 | SMAD family member 2 | 0.278 | ||
| SMAD1 | SMAD family member 1 | 0.234 | ||
| SMAD9 | SMAD family member 9 | 0.162 | ||
| JAG2 | jagged 2 | 0.132 | ||
| DCP1A | DCP1 decapping enzyme homolog A (S. cerevisiae) | 0.126 | ||
| MAML1 | mastermind-like 1 (Drosophila) | 0.125 | ||
| FBLN1 | fibulin 1 | 0.102 | ||
| CXXC5 | CXXC finger protein 5 | 0.074 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.072 | ||
| HEYL | hairy/enhancer-of-split related with YRPW motif-like | 0.068 | ||
| NOTCH3 | notch 3 | 0.067 | Human | |
| GATA4 | GATA binding protein 4 | 0.065 | Mouse | |
| TBX5 | T-box 5 | 0.065 | Zebrafish | |
| YY1 | YY1 transcription factor | 0.064 | ||
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.064 | ||
| ATF7IP | activating transcription factor 7 interacting protein | 0.061 | ||
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.058 | ||
| GATA1 | GATA binding protein 1 (globin transcription factor 1) | 0.058 | ||
| DCP1B | DCP1 decapping enzyme homolog B (S. cerevisiae) | 0.054 | ||
| TRIM33 | tripartite motif containing 33 | 0.053 | ||
| NCOR1 | nuclear receptor corepressor 1 | 0.050 | ||
| ZBED5 | zinc finger, BED-type containing 5 | 0.046 | ||
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.043 | ||
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.043 | ||
| TRIM29 | tripartite motif containing 29 | 0.040 | ||
| EGFL7 | EGF-like-domain, multiple 7 | 0.037 | ||
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.036 | ||
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.032 | ||
| EVC2 | Ellis van Creveld syndrome 2 | 0.032 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.030 | ||
| PLCD3 | phospholipase C, delta 3 | 0.030 | ||
| NR5A1 | nuclear receptor subfamily 5, group A, member 1 | 0.029 | ||
| NOTCH2NL | notch 2 N-terminal like | 0.029 | ||
| LAD1 | ladinin 1 | 0.029 | ||
| HIPK1 | homeodomain interacting protein kinase 1 | 0.028 | ||
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 | 0.028 | ||
| HMG20A | high mobility group 20A | 0.028 | ||
| EPAS1 | endothelial PAS domain protein 1 | 0.027 | ||
| HAND2 | heart and neural crest derivatives expressed 2 | 0.027 | ||
| NLK | nemo-like kinase | 0.026 | ||
| SMAD4 | SMAD family member 4 | 0.026 | Mouse | |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.025 | ||
| GATA2 | GATA binding protein 2 | 0.025 | Zebrafish | |
| DACH1 | dachshund homolog 1 (Drosophila) | 0.025 | ||
| GFI1B | growth factor independent 1B transcription repressor | 0.024 | ||
| RFX1 | regulatory factor X, 1 (influences HLA class II expression) | 0.024 | ||
| ZMYM2 | zinc finger, MYM-type 2 | 0.023 | ||
| CTBP2 | C-terminal binding protein 2 | 0.023 | ||
| PKP3 | plakophilin 3 | 0.021 | ||
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.021 | ||
| RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) | 0.021 | ||
| ITGB4 | integrin, beta 4 | 0.021 | ||
| HTT | huntingtin | 0.020 | ||
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.020 | ||
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.019 | ||
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.018 | ||
| SPEN | spen homolog, transcriptional regulator (Drosophila) | 0.018 | ||
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.018 | ||
| GJB3 | gap junction protein, beta 3, 31kDa | 0.018 | Human | |
| ATXN1L | ataxin 1-like | 0.017 | ||
| KLK10 | kallikrein-related peptidase 10 | 0.017 | ||
| SP1 | Sp1 transcription factor | 0.017 | ||
| ABTB1 | ankyrin repeat and BTB (POZ) domain containing 1 | 0.017 | ||
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.017 | ||
| ELN | elastin | 0.017 | ||
| TBX1 | T-box 1 | 0.016 | ||
| NPR1 | natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) | 0.016 | ||
| SOX17 | SRY (sex determining region Y)-box 17 | 0.016 | ||
| FOXF2 | forkhead box F2 | 0.016 | ||
| MKL2 | MKL/myocardin-like 2 | 0.015 | ||
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.015 | ||
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.015 | ||
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.014 | ||
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.014 | ||
| RIMS3 | regulating synaptic membrane exocytosis 3 | 0.014 | ||
| CLDN5 | claudin 5 | 0.014 | ||
| HIC1 | hypermethylated in cancer 1 | 0.014 | ||
| MBD1 | methyl-CpG binding domain protein 1 | 0.014 | ||
| HEY1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.014 | Mouse | |
| COL17A1 | collagen, type XVII, alpha 1 | 0.014 | ||
| PCDH1 | protocadherin 1 | 0.014 | ||
| MTMR10 | myotubularin related protein 10 | 0.014 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.014 | ||
| PPL | periplakin | 0.014 | ||
| SRI | sorcin | 0.014 | ||
| GMEB1 | glucocorticoid modulatory element binding protein 1 | 0.014 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.014 | ||
| NID1 | nidogen 1 | 0.014 | ||
| GJB5 | gap junction protein, beta 5, 31.1kDa | 0.014 | Human | |
| TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.013 | ||
| FGF18 | fibroblast growth factor 18 | 0.013 | ||
| TFPI2 | tissue factor pathway inhibitor 2 | 0.013 | ||
| HDLBP | high density lipoprotein binding protein | 0.013 | ||
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.013 | ||
| LMO4 | LIM domain only 4 | 0.013 | ||
| PROX1 | prospero homeobox 1 | 0.013 | ||
| CRHR2 | corticotropin releasing hormone receptor 2 | 0.013 | ||
| HES1 | hairy and enhancer of split 1, (Drosophila) | 0.013 | ||
| VWF | von Willebrand factor | 0.013 | ||
| INHBB | inhibin, beta B | 0.013 | ||
| THAP5 | THAP domain containing 5 | 0.013 | ||
| CYP11A1 | cytochrome P450, family 11, subfamily A, polypeptide 1 | 0.013 | ||
| HOXD12 | homeobox D12 | 0.013 | ||
| CD34 | CD34 molecule | 0.013 | ||
| KIAA1191 | KIAA1191 | 0.013 | ||
| ASB2 | ankyrin repeat and SOCS box containing 2 | 0.013 | ||
| PKP1 | plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) | 0.012 | ||
| FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.012 | ||
| TCF12 | transcription factor 12 | 0.012 | ||
| ZBTB7A | zinc finger and BTB domain containing 7A | 0.012 | ||
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.012 | ||
| BCAM | basal cell adhesion molecule (Lutheran blood group) | 0.012 | ||
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.012 | ||
| KRT6B | keratin 6B | 0.012 | ||
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.012 | ||
| LAMC2 | laminin, gamma 2 | 0.012 | ||
| TRIM62 | tripartite motif containing 62 | 0.012 | ||
| DOCK9 | dedicator of cytokinesis 9 | 0.012 | ||
| TMEM44 | transmembrane protein 44 | 0.012 | ||
| NIN | ninein (GSK3B interacting protein) | 0.012 | ||
| YAP1 | Yes-associated protein 1 | 0.012 | ||
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.012 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.012 | ||
| PAPPA2 | pappalysin 2 | 0.012 | ||
| NID2 | nidogen 2 (osteonidogen) | 0.012 | ||
| MCM3AP | minichromosome maintenance complex component 3 associated protein | 0.011 | ||
| DEFA1 | defensin, alpha 1 | 0.011 | ||
| AQP5 | aquaporin 5 | 0.011 | ||
| GPR116 | G protein-coupled receptor 116 | 0.011 | ||
| COL4A2 | collagen, type IV, alpha 2 | 0.011 | ||
| BCL3 | B-cell CLL/lymphoma 3 | 0.011 | ||
| C20orf4 | chromosome 20 open reading frame 4 | 0.011 | ||
| MTMR4 | myotubularin related protein 4 | 0.011 | ||
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.011 | ||
| DLL4 | delta-like 4 (Drosophila) | 0.011 | ||
| ANGPTL2 | angiopoietin-like 2 | 0.011 | ||
| C10orf54 | chromosome 10 open reading frame 54 | 0.011 | ||
| TCF15 | transcription factor 15 (basic helix-loop-helix) | 0.011 | ||
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 | 0.011 | ||
| LBX1 | ladybird homeobox 1 | 0.011 | ||
| THSD7A | thrombospondin, type I, domain containing 7A | 0.011 | ||
| TBX2 | T-box 2 | 0.011 | ||
| SRF | serum response factor (c-fos serum response element-binding transcription factor) | 0.011 | ||
| PSG9 | pregnancy specific beta-1-glycoprotein 9 | 0.011 | ||
| SNIP1 | Smad nuclear interacting protein 1 | 0.011 | ||
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 | 0.011 | ||
| POU2F1 | POU class 2 homeobox 1 | 0.010 | ||
| PYY | peptide YY | 0.010 | ||
| SOX13 | SRY (sex determining region Y)-box 13 | 0.010 | ||
| VGLL1 | vestigial like 1 (Drosophila) | 0.010 | ||
| HMGA2 | high mobility group AT-hook 2 | 0.010 | ||
| APLNR | apelin receptor | 0.010 | ||
| SMAD7 | SMAD family member 7 | 0.010 | ||
| ENTPD2 | ectonucleoside triphosphate diphosphohydrolase 2 | 0.010 | ||
| HOXB5 | homeobox B5 | 0.010 | ||
| ACAN | aggrecan | 0.010 | ||
| FOXO3 | forkhead box O3 | 0.010 |