IMP

Process View

Homo sapiens

2 genes annotated in human

Multi-species View

regulation of defense response to bacterium

GO:1900424

Any process that modulates the frequency, rate or extent of defense response to bacterium.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of defense response to bacterium"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of defense response to bacterium" (in gray)

Name	Description	Probability	Func Analog Organism
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.998
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.991
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.979
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.890	Fly
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.870
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.833
CHUK	conserved helix-loop-helix ubiquitous kinase	0.819	Fly
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.769	Fly
CRADD	CASP2 and RIPK1 domain containing adaptor with death domain	0.346
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.331	Fly
TNIP2	TNFAIP3 interacting protein 2	0.278
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.205	Fly
NLRC4	NLR family, CARD domain containing 4	0.197
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.168
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.163
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.118
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.089
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.069	Fly
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.065	Fly
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.062
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.050
CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)	0.047
RIPK2	receptor-interacting serine-threonine kinase 2	0.046
BTRC	beta-transducin repeat containing	0.025
PYCARD	PYD and CARD domain containing	0.024
BCL3	B-cell CLL/lymphoma 3	0.024
SQSTM1	sequestosome 1	0.022
FKBP5	FK506 binding protein 5	0.022
NLRC5	NLR family, CARD domain containing 5	0.022
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.021
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.021
SFRS18	splicing factor, arginine/serine-rich 18	0.020
ITGB1BP1	integrin beta 1 binding protein 1	0.020
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.020
ATM	ataxia telangiectasia mutated	0.019
CARD11	caspase recruitment domain family, member 11	0.018
MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	0.017
TRAF6	TNF receptor-associated factor 6	0.017
ELF4	E74-like factor 4 (ets domain transcription factor)	0.017
KEAP1	kelch-like ECH-associated protein 1	0.017
CARD16	caspase recruitment domain family, member 16	0.016
GOLGA6L9	golgin A6 family-like 9	0.016
IL18	interleukin 18 (interferon-gamma-inducing factor)	0.015
CAV1	caveolin 1, caveolae protein, 22kDa	0.015
USP20	ubiquitin specific peptidase 20	0.014
INADL	InaD-like (Drosophila)	0.014
BCL10	B-cell CLL/lymphoma 10	0.013
UROD	uroporphyrinogen decarboxylase	0.013
XIAP	X-linked inhibitor of apoptosis	0.013
MED12	mediator complex subunit 12	0.013
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.013
MDN1	MDN1, midasin homolog (yeast)	0.013
SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	0.012
MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	0.012
BEND5	BEN domain containing 5	0.012
PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	0.011
DCLRE1C	DNA cross-link repair 1C	0.011
IFI16	interferon, gamma-inducible protein 16	0.011
ELP2	elongation protein 2 homolog (S. cerevisiae)	0.011
MEN1	multiple endocrine neoplasia I	0.011
TNIP1	TNFAIP3 interacting protein 1	0.010
PSME4	proteasome (prosome, macropain) activator subunit 4	0.010
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.010
NCOA5	nuclear receptor coactivator 5	0.010