IMP

Process View

Mus musculus

16 genes annotated in mouse

Multi-species View

heme metabolic process

GO:0042168

The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "heme metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "heme metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.401	Mouse
Exoc6	exocyst complex component 6	0.389
Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	0.369
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.350	Mouse
Cyp2b9	cytochrome P450, family 2, subfamily b, polypeptide 9	0.350	Mouse
Mup5	major urinary protein 5	0.325
Cyp2c39	cytochrome P450, family 2, subfamily c, polypeptide 39	0.317	Mouse
Hbb-b2	hemoglobin, beta adult minor chain	0.296
Cyp2c29	cytochrome P450, family 2, subfamily c, polypeptide 29	0.278	Mouse
Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	0.260	Mouse
Keg1	kidney expressed gene 1	0.247
Akr1c6	aldo-keto reductase family 1, member C6	0.246
Cyp2c38	cytochrome P450, family 2, subfamily c, polypeptide 38	0.230	Mouse
Crp	C-reactive protein, pentraxin-related	0.209
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.206
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.198
Cyp4a14	cytochrome P450, family 4, subfamily a, polypeptide 14	0.172
Cps1	carbamoyl-phosphate synthetase 1	0.136
F9	coagulation factor IX	0.120
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.117
G6pc	glucose-6-phosphatase, catalytic	0.114
Spna1	spectrin alpha 1	0.111
Cyp2c54	cytochrome P450, family 2, subfamily c, polypeptide 54	0.099	Mouse
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.096	Mouse
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.092
Hrg	histidine-rich glycoprotein	0.091
Cfhr1	complement factor H-related 1	0.088
Cyp3a13	cytochrome P450, family 3, subfamily a, polypeptide 13	0.085
Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	0.085
Cml2	camello-like 2	0.085
Azgp1	alpha-2-glycoprotein 1, zinc	0.084
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.082
Krtap6-1	keratin associated protein 6-1	0.080
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.077
Ugt2a3	UDP glucuronosyltransferase 2 family, polypeptide A3	0.073
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.072
Aadac	arylacetamide deacetylase (esterase)	0.068
Rdh7	retinol dehydrogenase 7	0.060
Slco1b2	solute carrier organic anion transporter family, member 1b2	0.059
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.059
Pon1	paraoxonase 1	0.057
Otc	ornithine transcarbamylase	0.057
Tdo2	tryptophan 2,3-dioxygenase	0.054
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.049	Mouse
Hgd	homogentisate 1, 2-dioxygenase	0.048
Hamp	hepcidin antimicrobial peptide	0.048
Gsta2	glutathione S-transferase, alpha 2 (Yc2)	0.047
Pigr	polymeric immunoglobulin receptor	0.046
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.046
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.044
Taldo1	transaldolase 1	0.044
Upp2	uridine phosphorylase 2	0.044
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.043
Cyp2j5	cytochrome P450, family 2, subfamily j, polypeptide 5	0.042	Mouse
Cat	catalase	0.042
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.042	Mouse
Cyp4a12a	cytochrome P450, family 4, subfamily a, polypeptide 12a	0.041
Epb4.1	erythrocyte protein band 4.1	0.040
Mup3	major urinary protein 3	0.039
Inmt	indolethylamine N-methyltransferase	0.038
Hsd3b3	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3	0.038
Mbl2	mannose-binding lectin (protein C) 2	0.037
Cyp2b13	cytochrome P450, family 2, subfamily b, polypeptide 13	0.037
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.037
Spnb1	spectrin beta 1	0.036
Hmbs	hydroxymethylbilane synthase	0.036
Apcs	serum amyloid P-component	0.036
Tfrc	transferrin receptor	0.035
Tmprss15	transmembrane protease, serine 15	0.034
Apoh	apolipoprotein H	0.033
Vnn3	vanin 3	0.033
Cyp2c55	cytochrome P450, family 2, subfamily c, polypeptide 55	0.033
Afm	afamin	0.033
Pnpo	pyridoxine 5'-phosphate oxidase	0.033
Fmo1	flavin containing monooxygenase 1	0.032
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.032
Cyp2g1	cytochrome P450, family 2, subfamily g, polypeptide 1	0.032	Mouse
F13b	coagulation factor XIII, beta subunit	0.032
Cyp2d9	cytochrome P450, family 2, subfamily d, polypeptide 9	0.031
Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	0.031
Acot12	acyl-CoA thioesterase 12	0.031
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.031	Mouse
Sult1d1	sulfotransferase family 1D, member 1	0.031
Gm14743	predicted gene 14743	0.030
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.030
Olfr2	olfactory receptor 2	0.030
Alb	albumin	0.029
Uros	uroporphyrinogen III synthase	0.029
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.029
Glyat	glycine-N-acyltransferase	0.029
Akr1d1	aldo-keto reductase family 1, member D1	0.028
Pik3c2g	phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide	0.028
Hc	hemolytic complement	0.028
Sult1b1	sulfotransferase family 1B, member 1	0.028
Prlr	prolactin receptor	0.028
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.027
Ces1d	carboxylesterase 1D	0.027
Cyp4a31	cytochrome P450, family 4, subfamily a, polypeptide 31	0.027
Abcc2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.027
Sult2a2	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2	0.026
Dio1	deiodinase, iodothyronine, type I	0.026
Olfr67	olfactory receptor 67	0.026
Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	0.026
Saa4	serum amyloid A 4	0.025
Apob	apolipoprotein B	0.025
Tat	tyrosine aminotransferase	0.025
Uqcrfs1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	0.024
Gsta3	glutathione S-transferase, alpha 3	0.024
Hfe	hemochromatosis	0.024
Glrx5	glutaredoxin 5 homolog (S. cerevisiae)	0.024
Atp5g3	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)	0.024
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.023
Fbxl5	F-box and leucine-rich repeat protein 5	0.023
Apoc4	apolipoprotein C-IV	0.023
Ces1g	carboxylesterase 1G	0.023
Slc17a1	solute carrier family 17 (sodium phosphate), member 1	0.023
Hpd	4-hydroxyphenylpyruvic acid dioxygenase	0.022
Alad	aminolevulinate, delta-, dehydratase	0.022
Fmo4	flavin containing monooxygenase 4	0.022
Ugt3a2	UDP glycosyltransferases 3 family, polypeptide A2	0.022
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.021
Pah	phenylalanine hydroxylase	0.021
Bhmt	betaine-homocysteine methyltransferase	0.021
Vsig4	V-set and immunoglobulin domain containing 4	0.021
Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	0.021
D730048I06Rik	RIKEN cDNA D730048I06 gene	0.021
BC089597	cDNA sequence BC089597	0.020
Avpr1a	arginine vasopressin receptor 1A	0.020
Adh4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.020
Mug1	murinoglobulin 1	0.020
2810459M11Rik	RIKEN cDNA 2810459M11 gene	0.020
Tex12	testis expressed gene 12	0.020
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.020
Ugt3a1	UDP glycosyltransferases 3 family, polypeptide A1	0.020
Dhrs4	dehydrogenase/reductase (SDR family) member 4	0.019
C730048C13Rik	RIKEN cDNA C730048C13 gene	0.019
Cyp2c37	cytochrome P450, family 2. subfamily c, polypeptide 37	0.019	Mouse
Ugt2b38	UDP glucuronosyltransferase 2 family, polypeptide B38	0.019
Creb3l3	cAMP responsive element binding protein 3-like 3	0.019
Cfhr2	complement factor H-related 2	0.019
Bche	butyrylcholinesterase	0.019
Ugt2b34	UDP glucuronosyltransferase 2 family, polypeptide B34	0.018
D630002G06Rik	RIKEN cDNA D630002G06 gene	0.018
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.018
Aldh8a1	aldehyde dehydrogenase 8 family, member A1	0.018
Gpr12	G-protein coupled receptor 12	0.018
Cd68	CD68 antigen	0.018
Cyp2c68	cytochrome P450, family 2, subfamily c, polypeptide 68	0.018
Ces2a	carboxylesterase 2A	0.018
Slc22a18	solute carrier family 22 (organic cation transporter), member 18	0.018
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.017
Bbox1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)	0.017
C9	complement component 9	0.017
Pet2	plasmacytoma expressed transcript 2	0.017
Fmo3	flavin containing monooxygenase 3	0.016
Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	0.016
Gc	group specific component	0.016
Blvrb	biliverdin reductase B (flavin reductase (NADPH))	0.016
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.016
Fbp1	fructose bisphosphatase 1	0.016
Fmo2	flavin containing monooxygenase 2	0.016
Sult1a1	sulfotransferase family 1A, phenol-preferring, member 1	0.016
Ak2	adenylate kinase 2	0.016
Fpr1	formyl peptide receptor 1	0.016
Ptk6	PTK6 protein tyrosine kinase 6	0.016
Cyp3a44	cytochrome P450, family 3, subfamily a, polypeptide 44	0.016
Defa15	defensin, alpha, 15	0.016
Adamdec1	ADAM-like, decysin 1	0.016
Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.016
Ces1f	carboxylesterase 1F	0.015
Cs	citrate synthase	0.015
Acaa2	acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)	0.015
Dpyd	dihydropyrimidine dehydrogenase	0.015
Olfr74	olfactory receptor 74	0.015
F2	coagulation factor II	0.015
BC014805	cDNA sequence BC014805	0.014
Cyp2j11	cytochrome P450, family 2, subfamily j, polypeptide 11	0.014	Mouse
Ugt2b37	UDP glucuronosyltransferase 2 family, polypeptide B37	0.014
Etfb	electron transferring flavoprotein, beta polypeptide	0.014
Tas2r105	taste receptor, type 2, member 105	0.014
Heph	hephaestin	0.014
Aldob	aldolase B, fructose-bisphosphate	0.014
Btc	betacellulin, epidermal growth factor family member	0.014
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.014
Sord	sorbitol dehydrogenase	0.014
Slco1a4	solute carrier organic anion transporter family, member 1a4	0.014	Mouse
Smr2	submaxillary gland androgen regulated protein 2	0.014
Orm3	orosomucoid 3	0.014
Slc6a18	solute carrier family 6 (neurotransmitter transporter), member 18	0.014
Vmn1r56	vomeronasal 1 receptor 56	0.014
Gm2717	predicted gene 2717	0.013
Hbb-b1	hemoglobin, beta adult major chain	0.013
Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	0.013
AB056442	cDNA sequence AB056442	0.013
Ank1	ankyrin 1, erythroid	0.013
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.013
F7	coagulation factor VII	0.013
Krtap4-2	keratin associated protein 4-2	0.013
Akr1c21	aldo-keto reductase family 1, member C21	0.013
Lect2	leukocyte cell-derived chemotaxin 2	0.013
Gstm6	glutathione S-transferase, mu 6	0.013
Uqcrc1	ubiquinol-cytochrome c reductase core protein 1	0.013
Dmgdh	dimethylglycine dehydrogenase precursor	0.013
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.013
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.013
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.013
2810007J24Rik	RIKEN cDNA 2810007J24 gene	0.013
Akr1c20	aldo-keto reductase family 1, member C20	0.012
Defb1	defensin beta 1	0.012
Acnat2	acyl-coenzyme A amino acid N-acyltransferase 2	0.012
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.012
Gm10228	predicted gene 10228	0.012
Cdh9	cadherin 9	0.012
Bhmt2	betaine-homocysteine methyltransferase 2	0.012
Urod	uroporphyrinogen decarboxylase	0.012
Apoc3	apolipoprotein C-III	0.012
Lce1c	late cornified envelope 1C	0.012
Iyd	iodotyrosine deiodinase	0.012
Psma4	proteasome (prosome, macropain) subunit, alpha type 4	0.012
Acox2	acyl-Coenzyme A oxidase 2, branched chain	0.012
Hdhd3	haloacid dehalogenase-like hydrolase domain containing 3	0.012
Hao1	hydroxyacid oxidase 1, liver	0.012
Olfr480	olfactory receptor 480	0.012
Rad21	RAD21 homolog (S. pombe)	0.012
Fmo5	flavin containing monooxygenase 5	0.011
Cd5l	CD5 antigen-like	0.011
Slc17a3	solute carrier family 17 (sodium phosphate), member 3	0.011
Abcb7	ATP-binding cassette, sub-family B (MDR/TAP), member 7	0.011
Gstm3	glutathione S-transferase, mu 3	0.011
Acsm3	acyl-CoA synthetase medium-chain family member 3	0.011
Vmn1r47	vomeronasal 1 receptor 47	0.011
Sdhd	succinate dehydrogenase complex, subunit D, integral membrane protein	0.011
Cyp4f15	cytochrome P450, family 4, subfamily f, polypeptide 15	0.011
Sec14l4	SEC14-like 4 (S. cerevisiae)	0.011
Mavs	mitochondrial antiviral signaling protein	0.011
Nudt1	nudix (nucleoside diphosphate linked moiety X)-type motif 1	0.011
Cyp2c69	cytochrome P450, family 2, subfamily c, polypeptide 69	0.011
Krtap16-9	keratin associated protein 16-9	0.011
Cyp2a5	cytochrome P450, family 2, subfamily a, polypeptide 5	0.011
Krtap13	keratin associated protein 13	0.011
Mpv17	MpV17 mitochondrial inner membrane protein	0.011
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.011
Kap	kidney androgen regulated protein	0.011
Ces1e	carboxylesterase 1E	0.011
Umod	uromodulin	0.011
Slc17a2	solute carrier family 17 (sodium phosphate), member 2	0.011
C8a	complement component 8, alpha polypeptide	0.011
Saa2	serum amyloid A 2	0.011
Sema4f	sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain	0.011
Hba-a2	hemoglobin alpha, adult chain 2	0.011
Mat1a	methionine adenosyltransferase I, alpha	0.010
Aadat	aminoadipate aminotransferase	0.010
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.010
Abcb11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.010
Dct	dopachrome tautomerase	0.010
Acot4	acyl-CoA thioesterase 4	0.010
Mup4	major urinary protein 4	0.010
Rhbg	Rhesus blood group-associated B glycoprotein	0.010
Mpv17l	Mpv17 transgene, kidney disease mutant-like	0.010
Olfr65	olfactory receptor 65	0.010