IMP

Process View

Mus musculus

9 genes annotated in mouse

Multi-species View

epithelial structure maintenance

GO:0010669

A tissue homeostatic process required for the maintenance of epithelial structure.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "epithelial structure maintenance"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "epithelial structure maintenance" (in gray)

Name	Description	Probability	Func Analog Organism
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.826
Isl1	ISL1 transcription factor, LIM/homeodomain	0.506
Emx1	empty spiracles homolog 1 (Drosophila)	0.471
Neurog2	neurogenin 2	0.470	Mouse
Pax6	paired box gene 6	0.354
Raver2	ribonucleoprotein, PTB-binding 2	0.317
Otx2	orthodenticle homolog 2 (Drosophila)	0.315
Sox2	SRY-box containing gene 2	0.250	Mouse
Neurod1	neurogenic differentiation 1	0.246
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.181
Shh	sonic hedgehog	0.179
Nf1	neurofibromatosis 1	0.144
Sox11	SRY-box containing gene 11	0.126	Mouse
Hand1	heart and neural crest derivatives expressed transcript 1	0.113	Mouse
Nhlh1	nescient helix loop helix 1	0.100	Mouse
She	src homology 2 domain-containing transforming protein E	0.092
Gli3	GLI-Kruppel family member GLI3	0.092
Onecut1	one cut domain, family member 1	0.087
Pax3	paired box gene 3	0.086
Lhx3	LIM homeobox protein 3	0.084
Meox2	mesenchyme homeobox 2	0.082
Hes1	hairy and enhancer of split 1 (Drosophila)	0.074
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.065
Cdx2	caudal type homeobox 2	0.062
Ptf1a	pancreas specific transcription factor, 1a	0.061	Mouse
Gata4	GATA binding protein 4	0.060
Aplnr	apelin receptor	0.059
Tcfap2a	transcription factor AP-2, alpha	0.059
Insm1	insulinoma-associated 1	0.058
Tlr4	toll-like receptor 4	0.054
Cdc73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.052
Cldn5	claudin 5	0.050
Runx2	runt related transcription factor 2	0.049
Ccr2	chemokine (C-C motif) receptor 2	0.048
Gata1	GATA binding protein 1	0.045
Prrx1	paired related homeobox 1	0.043
Alx3	aristaless-like homeobox 3	0.041
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.040
Ptprb	protein tyrosine phosphatase, receptor type, B	0.039
Gja4	gap junction protein, alpha 4	0.039
Sox4	SRY-box containing gene 4	0.038	Mouse
Hand2	heart and neural crest derivatives expressed transcript 2	0.037	Mouse
Pitx1	paired-like homeodomain transcription factor 1	0.036
Sox17	SRY-box containing gene 17	0.035	Mouse
Ssbp3	single-stranded DNA binding protein 3	0.035
Hbb-bh1	hemoglobin Z, beta-like embryonic chain	0.035
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.034
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.034
Tcf3	transcription factor 3	0.033
Gnrh1	gonadotropin releasing hormone 1	0.033
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.032
Hoxd13	homeobox D13	0.032
Ticam1	toll-like receptor adaptor molecule 1	0.031
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.030
Fgf4	fibroblast growth factor 4	0.030
Hoxa5	homeobox A5	0.029
Col1a1	collagen, type I, alpha 1	0.028
Casp1	caspase 1	0.027
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.026
Gpr50	G-protein-coupled receptor 50	0.026
Atoh7	atonal homolog 7 (Drosophila)	0.025	Mouse
Alx4	aristaless-like homeobox 4	0.025
Il10	interleukin 10	0.025
Hesx1	homeobox gene expressed in ES cells	0.025
Tlr2	toll-like receptor 2	0.025	Mouse
Hnf4a	hepatic nuclear factor 4, alpha	0.025
Hhex	hematopoietically expressed homeobox	0.025
Hbb-y	hemoglobin Y, beta-like embryonic chain	0.024
Efna2	ephrin A2	0.023
Zic1	zinc finger protein of the cerebellum 1	0.023
Neurod4	neurogenic differentiation 4	0.022	Mouse
Cd14	CD14 antigen	0.021
Mecom	MDS1 and EVI1 complex locus	0.021
Cel	carboxyl ester lipase	0.020
Emcn	endomucin	0.020
Cmklr1	chemokine-like receptor 1	0.019
Olig2	oligodendrocyte transcription factor 2	0.019
Kdr	kinase insert domain protein receptor	0.019
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.019
Sox18	SRY-box containing gene 18	0.019	Mouse
Prox1	prospero-related homeobox 1	0.019
Tcf15	transcription factor 15	0.019	Mouse
Cdh5	cadherin 5	0.018
Sox7	SRY-box containing gene 7	0.018	Mouse
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.018
Pdx1	pancreatic and duodenal homeobox 1	0.018
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.018
Myd88	myeloid differentiation primary response gene 88	0.018
Ccl2	chemokine (C-C motif) ligand 2	0.018
Efs	embryonal Fyn-associated substrate	0.018
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.018
Foxd1	forkhead box D1	0.018
Meox1	mesenchyme homeobox 1	0.017
Nos3	nitric oxide synthase 3, endothelial cell	0.017
Foxd2	forkhead box D2	0.017
Mab21l2	mab-21-like 2 (C. elegans)	0.017
Cdca3	cell division cycle associated 3	0.017
Col2a1	collagen, type II, alpha 1	0.017
Gdf11	growth differentiation factor 11	0.017
Fhl3	four and a half LIM domains 3	0.017
Pkd1	polycystic kidney disease 1 homolog	0.016
Lef1	lymphoid enhancer binding factor 1	0.016
Bcl6b	B-cell CLL/lymphoma 6, member B	0.016
Zfhx3	zinc finger homeobox 3	0.016
Pou4f2	POU domain, class 4, transcription factor 2	0.016
Lair1	leukocyte-associated Ig-like receptor 1	0.016
Lmo2	LIM domain only 2	0.015
Tal2	T-cell acute lymphocytic leukemia 2	0.015	Mouse
Spp1	secreted phosphoprotein 1	0.015
Fli1	Friend leukemia integration 1	0.015
Galr1	galanin receptor 1	0.015
Hes5	hairy and enhancer of split 5 (Drosophila)	0.015
Sall3	sal-like 3 (Drosophila)	0.014
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.014
Lmo1	LIM domain only 1	0.014
Lep	leptin	0.014
Myct1	myc target 1	0.014
Pou2f2	POU domain, class 2, transcription factor 2	0.014
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.013
Sox9	SRY-box containing gene 9	0.013
Hmga2	high mobility group AT-hook 2	0.013
Gja1	gap junction protein, alpha 1	0.013
Rb1	retinoblastoma 1	0.013
Ebf3	early B-cell factor 3	0.013
En1	engrailed 1	0.013
Plac1	placental specific protein 1	0.013
Dlk1	delta-like 1 homolog (Drosophila)	0.013
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.013
Nkx3-2	NK3 homeobox 2	0.013
Lhx5	LIM homeobox protein 5	0.013
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.012
Krt17	keratin 17	0.012
Hoxb5	homeobox B5	0.012
Mfng	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.012
Col9a1	collagen, type IX, alpha 1	0.012
Hoxa2	homeobox A2	0.012
Atoh1	atonal homolog 1 (Drosophila)	0.012	Mouse
Nkx6-1	NK6 homeobox 1	0.012
Rasip1	Ras interacting protein 1	0.012
Cd300ld	CD300 molecule-like family member d	0.012
BC013712	cDNA sequence BC013712	0.012
Acin1	apoptotic chromatin condensation inducer 1	0.012
Tlr1	toll-like receptor 1	0.012	Mouse
Lhx9	LIM homeobox protein 9	0.011
Pitx2	paired-like homeodomain transcription factor 2	0.011
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.011
Bmp2	bone morphogenetic protein 2	0.011
Fbn2	fibrillin 2	0.011
Gypa	glycophorin A	0.011
Adcy4	adenylate cyclase 4	0.011
Eya1	eyes absent 1 homolog (Drosophila)	0.011
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.011
Mc3r	melanocortin 3 receptor	0.011
Npas1	neuronal PAS domain protein 1	0.011
Clec14a	C-type lectin domain family 14, member a	0.011
Aim2	absent in melanoma 2	0.010
Kiss1	KiSS-1 metastasis-suppressor	0.010