IMP

Process View

Mus musculus

1 genes annotated in mouse

regulation of membrane depolarization during action potential

Any process that modulates the rate, frequency or extent of membrane depolarization during an action potential. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of membrane depolarization during action potential"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of membrane depolarization during action potential" (in gray)

Name	Description	Probability	Func Analog Organism
Scn5a	sodium channel, voltage-gated, type V, alpha	0.991
Tjp1	tight junction protein 1	0.919
Tbx5	T-box 5	0.840
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.834
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.393
Tbx3	T-box 3	0.356
Nos3	nitric oxide synthase 3, endothelial cell	0.345
Ryr2	ryanodine receptor 2, cardiac	0.330
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.271
Gjb2	gap junction protein, beta 2	0.269	Mouse
Gjb4	gap junction protein, beta 4	0.263	Mouse
Gjb6	gap junction protein, beta 6	0.201	Mouse
Fut1	fucosyltransferase 1	0.201
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.201
F12	coagulation factor XII (Hageman factor)	0.194
Dsc1	desmocollin 1	0.156
Col13a1	collagen, type XIII, alpha 1	0.147
Pcdh12	protocadherin 12	0.145
Kel	Kell blood group	0.145
Fut2	fucosyltransferase 2	0.124
Nppc	natriuretic peptide type C	0.106
Ntf3	neurotrophin 3	0.101
Mt4	metallothionein 4	0.087
Gjb3	gap junction protein, beta 3	0.082	Mouse
Rhox6	reproductive homeobox 6	0.080
Csda	cold shock domain protein A	0.079
Slurp1	secreted Ly6/Plaur domain containing 1	0.078
Il11	interleukin 11	0.076
Defa-rs12	defensin, alpha, related sequence 12	0.076
Klk6	kallikrein related-peptidase 6	0.073
Zfpm2	zinc finger protein, multitype 2	0.071
Ivl	involucrin	0.062
Krt15	keratin 15	0.059
Rcvrn	recoverin	0.057
Dmkn	dermokine	0.055
Slc26a4	solute carrier family 26, member 4	0.053
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.053
Tmem40	transmembrane protein 40	0.052
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.051
Msx2	homeobox, msh-like 2	0.050
Krt31	keratin 31	0.050
Scarb2	scavenger receptor class B, member 2	0.049
Gjb5	gap junction protein, beta 5	0.049	Mouse
Ighmbp2	immunoglobulin mu binding protein 2	0.048
Lgals7	lectin, galactose binding, soluble 7	0.046
Crygd	crystallin, gamma D	0.045
Ghrh	growth hormone releasing hormone	0.045
Bfsp1	beaded filament structural protein 1, in lens-CP94	0.044
Tcfap2c	transcription factor AP-2, gamma	0.042
Pla2g4f	phospholipase A2, group IVF	0.042
H1foo	H1 histone family, member O, oocyte-specific	0.042
Krt17	keratin 17	0.042
Ltbp1	latent transforming growth factor beta binding protein 1	0.042
Krt16	keratin 16	0.041
Scn10a	sodium channel, voltage-gated, type X, alpha	0.040
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.040
Il1f5	interleukin 1 family, member 5 (delta)	0.039
Kit	kit oncogene	0.039
Fgf17	fibroblast growth factor 17	0.038
Col17a1	collagen, type XVII, alpha 1	0.038
Hopx	HOP homeobox	0.037
Oprd1	opioid receptor, delta 1	0.036
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.036
Sstr3	somatostatin receptor 3	0.036
Prph2	peripherin 2	0.036
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.036
Krt25	keratin 25	0.036
Rem1	rad and gem related GTP binding protein 1	0.035
Npas1	neuronal PAS domain protein 1	0.035
Serpinb5	serine (or cysteine) peptidase inhibitor, clade B, member 5	0.035
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.034
Phlda2	pleckstrin homology-like domain, family A, member 2	0.034
Sstr1	somatostatin receptor 1	0.034
Tgfb2	transforming growth factor, beta 2	0.034
Dmd	dystrophin, muscular dystrophy	0.033
Slc5a11	solute carrier family 5 (sodium/glucose cotransporter), member 11	0.033
Lmna	lamin A	0.033
Elf5	E74-like factor 5	0.031
Clic3	chloride intracellular channel 3	0.030
Gpc3	glypican 3	0.030
Ly6g6d	lymphocyte antigen 6 complex, locus G6D	0.029
Lrp2	low density lipoprotein receptor-related protein 2	0.029
Sox18	SRY-box containing gene 18	0.029
Itgb4	integrin beta 4	0.028
Nid1	nidogen 1	0.028
Krt13	keratin 13	0.028
Crct1	cysteine-rich C-terminal 1	0.028
Btbd17	BTB (POZ) domain containing 17	0.028
Aldh3a1	aldehyde dehydrogenase family 3, subfamily A1	0.027
Krt5	keratin 5	0.027
Mog	myelin oligodendrocyte glycoprotein	0.027
Ldb3	LIM domain binding 3	0.026
Nxph1	neurexophilin 1	0.026
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.026
Cdsn	corneodesmosin	0.026
Gli1	GLI-Kruppel family member GLI1	0.026
Rab17	RAB17, member RAS oncogene family	0.026
Gja1	gap junction protein, alpha 1	0.026	Mouse
S100a14	S100 calcium binding protein A14	0.026
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.026
Tff2	trefoil factor 2 (spasmolytic protein 1)	0.026
Htr3b	5-hydroxytryptamine (serotonin) receptor 3B	0.025
Krt14	keratin 14	0.025
Krt36	keratin 36	0.025
Cldn3	claudin 3	0.024
Tg	thyroglobulin	0.024
Htr5a	5-hydroxytryptamine (serotonin) receptor 5A	0.024
Gja8	gap junction protein, alpha 8	0.024	Mouse
Espn	espin	0.024
Wnt7a	wingless-related MMTV integration site 7A	0.024
Atp6v0a4	ATPase, H+ transporting, lysosomal V0 subunit A4	0.024
Cryba4	crystallin, beta A4	0.023
Bdkrb2	bradykinin receptor, beta 2	0.023
Col22a1	collagen, type XXII, alpha 1	0.023
Grk1	G protein-coupled receptor kinase 1	0.023
Scn1a	sodium channel, voltage-gated, type I, alpha	0.023
Klk10	kallikrein related-peptidase 10	0.023
Sall4	sal-like 4 (Drosophila)	0.023
Wfdc2	WAP four-disulfide core domain 2	0.023
Dmrt1	doublesex and mab-3 related transcription factor 1	0.023
Mst1	macrophage stimulating 1 (hepatocyte growth factor-like)	0.023
Tcf15	transcription factor 15	0.023
Lhx5	LIM homeobox protein 5	0.023
Col9a2	collagen, type IX, alpha 2	0.023
Edn2	endothelin 2	0.023
Ednrb	endothelin receptor type B	0.022
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.022
Chrng	cholinergic receptor, nicotinic, gamma polypeptide	0.022
Crybb1	crystallin, beta B1	0.022
Fabp9	fatty acid binding protein 9, testis	0.022
Insm2	insulinoma-associated 2	0.021
Xirp1	xin actin-binding repeat containing 1	0.021
Tmprss5	transmembrane protease, serine 5 (spinesin)	0.021
Tsg101	tumor susceptibility gene 101	0.021
Fgg	fibrinogen gamma chain	0.021
Tead4	TEA domain family member 4	0.021
Atoh7	atonal homolog 7 (Drosophila)	0.020
Msln	mesothelin	0.020
Bmp8b	bone morphogenetic protein 8b	0.020
Foxd3	forkhead box D3	0.020
Sox15	SRY-box containing gene 15	0.020
Abca4	ATP-binding cassette, sub-family A (ABC1), member 4	0.020
Slc18a3	solute carrier family 18 (vesicular monoamine), member 3	0.020
Dmp1	dentin matrix protein 1	0.020
Emp2	epithelial membrane protein 2	0.019
Bnipl	BCL2/adenovirus E1B 19kD interacting protein like	0.019
Pkp3	plakophilin 3	0.019
Gm10334	predicted gene 10334	0.019
Krtap6-3	keratin associated protein 6-3	0.019
Sfn	stratifin	0.019
Krtap3-3	keratin associated protein 3-3	0.018
Slc46a2	solute carrier family 46, member 2	0.018
Ambp	alpha 1 microglobulin/bikunin	0.018
Adam28	a disintegrin and metallopeptidase domain 28	0.018
Fgf2	fibroblast growth factor 2	0.018
Lrrc15	leucine rich repeat containing 15	0.018
Rln1	relaxin 1	0.018
Sprr1b	small proline-rich protein 1B	0.018
Tnni2	troponin I, skeletal, fast 2	0.018
Atp4b	ATPase, H+/K+ exchanging, beta polypeptide	0.018
Lman1l	lectin, mannose-binding 1 like	0.018
Dok5	docking protein 5	0.018
Kcnab3	potassium voltage-gated channel, shaker-related subfamily, beta member 3	0.018
Lypd3	Ly6/Plaur domain containing 3	0.018
Crhr2	corticotropin releasing hormone receptor 2	0.018
Crabp2	cellular retinoic acid binding protein II	0.018
Matn4	matrilin 4	0.017
Ckmt2	creatine kinase, mitochondrial 2	0.017
Crabp1	cellular retinoic acid binding protein I	0.017
Oc90	otoconin 90	0.017
U46068	cDNA sequence U46068	0.017
Ear5	eosinophil-associated, ribonuclease A family, member 5	0.017
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.017
Hmx1	H6 homeobox 1	0.017
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.017
Upk3b	uroplakin 3B	0.017
Cdh3	cadherin 3	0.016
Rlbp1	retinaldehyde binding protein 1	0.016
Galr2	galanin receptor 2	0.016
Cpz	carboxypeptidase Z	0.016
Sox1	SRY-box containing gene 1	0.016
Rab25	RAB25, member RAS oncogene family	0.016
Pax6	paired box gene 6	0.016
Calcoco2	calcium binding and coiled-coil domain 2	0.016
Gp9	glycoprotein 9 (platelet)	0.016
Anxa8	annexin A8	0.016
Ngf	nerve growth factor	0.016
Itga7	integrin alpha 7	0.015
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.015
Musk	muscle, skeletal, receptor tyrosine kinase	0.015
Agxt	alanine-glyoxylate aminotransferase	0.015
Gpr45	G protein-coupled receptor 45	0.015
Irx3	Iroquois related homeobox 3 (Drosophila)	0.015
Wnt8a	wingless-related MMTV integration site 8A	0.015
Smn1	survival motor neuron 1	0.015
Krt34	keratin 34	0.015
Krtap16-1	keratin associated protein 16-1	0.015
Sox7	SRY-box containing gene 7	0.015
Bmp2	bone morphogenetic protein 2	0.015
Cnst	consortin, connexin sorting protein	0.015
Eln	elastin	0.015
Abcb1a	ATP-binding cassette, sub-family B (MDR/TAP), member 1A	0.015
Krtap5-1	keratin associated protein 5-1	0.015
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.015
Cdx1	caudal type homeobox 1	0.015
Nanog	Nanog homeobox	0.015
Krt72-ps	keratin 72, pseudogene	0.015
Uncx	UNC homeobox	0.015
6330527O06Rik	RIKEN cDNA 6330527O06 gene	0.014
Olig2	oligodendrocyte transcription factor 2	0.014
Cacna2d2	calcium channel, voltage-dependent, alpha 2/delta subunit 2	0.014
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.014
Alox12b	arachidonate 12-lipoxygenase, 12R type	0.014
BC051019	cDNA sequence BC051019	0.014
Megf11	multiple EGF-like-domains 11	0.014
Cdx2	caudal type homeobox 2	0.014
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.014
Artn	artemin	0.014
Prss22	protease, serine, 22	0.014
Dsc3	desmocollin 3	0.014
9930023K05Rik	RIKEN cDNA 9930023K05 gene	0.014
Mdfi	MyoD family inhibitor	0.014
Sult4a1	sulfotransferase family 4A, member 1	0.014
Cnr1	cannabinoid receptor 1 (brain)	0.014
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.013
Eppk1	epiplakin 1	0.013
Rs1	retinoschisis (X-linked, juvenile) 1 (human)	0.013
Fam3b	family with sequence similarity 3, member B	0.013
Krt35	keratin 35	0.013
Ehf	ets homologous factor	0.013
Gad2	glutamic acid decarboxylase 2	0.013
Kcnk7	potassium channel, subfamily K, member 7	0.013
Sost	sclerostin	0.013
Pou3f2	POU domain, class 3, transcription factor 2	0.013
Nphs2	nephrosis 2 homolog, podocin (human)	0.013
Aqp3	aquaporin 3	0.013
Cnn1	calponin 1	0.013
Asgr2	asialoglycoprotein receptor 2	0.013
Il31	interleukin 31	0.013
5730559C18Rik	RIKEN cDNA 5730559C18 gene	0.013
Lamc2	laminin, gamma 2	0.013
Oit1	oncoprotein induced transcript 1	0.013
Mal	myelin and lymphocyte protein, T-cell differentiation protein	0.012
Adra1b	adrenergic receptor, alpha 1b	0.012
Myom2	myomesin 2	0.012
Trh	thyrotropin releasing hormone	0.012
Tulp1	tubby like protein 1	0.012
Ptgs2	prostaglandin-endoperoxide synthase 2	0.012
Mpz	myelin protein zero	0.012
Krtap3-1	keratin associated protein 3-1	0.012
Epha2	Eph receptor A2	0.012
Sardh	sarcosine dehydrogenase	0.012
BC024139	cDNA sequence BC024139	0.012
Ttr	transthyretin	0.012
Ereg	epiregulin	0.012
Pthlh	parathyroid hormone-like peptide	0.012
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.012
Tacstd2	tumor-associated calcium signal transducer 2	0.012
Sall1	sal-like 1 (Drosophila)	0.012
Asgr1	asialoglycoprotein receptor 1	0.012
Hes3	hairy and enhancer of split 3 (Drosophila)	0.012
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.012
Gdnf	glial cell line derived neurotrophic factor	0.012
Slc29a2	solute carrier family 29 (nucleoside transporters), member 2	0.012
Sycn	syncollin	0.012
Degs2	degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase	0.012
Cldn4	claudin 4	0.012
Tmem54	transmembrane protein 54	0.012
Epn3	epsin 3	0.012
Crym	crystallin, mu	0.012
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.012
A4galt	alpha 1,4-galactosyltransferase	0.012
Cnga3	cyclic nucleotide gated channel alpha 3	0.012
AA675344	expressed sequence AA675344	0.012
Foxd2	forkhead box D2	0.012
Gkn1	gastrokine 1	0.011
Slc1a6	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	0.011
Fstl3	follistatin-like 3	0.011
Map3k6	mitogen-activated protein kinase kinase kinase 6	0.011
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.011
Tcf23	transcription factor 23	0.011
Dhh	desert hedgehog	0.011
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.011
5430421N21Rik	RIKEN cDNA 5430421N21 gene	0.011
Jag1	jagged 1	0.011
Krtap9-3	keratin associated protein 9-3	0.011
Kcns1	K+ voltage-gated channel, subfamily S, 1	0.011
H2-M9	histocompatibility 2, M region locus 9	0.011
Adam17	a disintegrin and metallopeptidase domain 17	0.011
Col8a1	collagen, type VIII, alpha 1	0.011
Gnat1	guanine nucleotide binding protein, alpha transducing 1	0.011
Gsdma	gasdermin A	0.011
Omp	olfactory marker protein	0.011
Myh8	myosin, heavy polypeptide 8, skeletal muscle, perinatal	0.011
Tagln3	transgelin 3	0.011
Amhr2	anti-Mullerian hormone type 2 receptor	0.011
Wnt9a	wingless-type MMTV integration site 9A	0.011
Dppa3	developmental pluripotency-associated 3	0.011
Lcn5	lipocalin 5	0.011
Fezf2	Fez family zinc finger 2	0.011
Podxl	podocalyxin-like	0.010
A2m	alpha-2-macroglobulin	0.010
Fabp6	fatty acid binding protein 6, ileal (gastrotropin)	0.010
Sprr1a	small proline-rich protein 1A	0.010
Cmklr1	chemokine-like receptor 1	0.010
Prph	peripherin	0.010
Stra6	stimulated by retinoic acid gene 6	0.010
Myh3	myosin, heavy polypeptide 3, skeletal muscle, embryonic	0.010
Cst11	cystatin 11	0.010
Trim29	tripartite motif-containing 29	0.010
Dpep3	dipeptidase 3	0.010
Stac	src homology three (SH3) and cysteine rich domain	0.010
Ly6g6c	lymphocyte antigen 6 complex, locus G6C	0.010
Fgf12	fibroblast growth factor 12	0.010
Cldn5	claudin 5	0.010
Syt8	synaptotagmin VIII	0.010
Nepn	nephrocan	0.010
Prodh2	proline dehydrogenase (oxidase) 2	0.010
Hoxd13	homeobox D13	0.010
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.010
Foxe3	forkhead box E3	0.010
Lama1	laminin, alpha 1	0.010
Col4a4	collagen, type IV, alpha 4	0.010
Gabrd	gamma-aminobutyric acid (GABA) A receptor, subunit delta	0.010
Ckmt1	creatine kinase, mitochondrial 1, ubiquitous	0.010
Spink3	serine peptidase inhibitor, Kazal type 3	0.010
Rhpn1	rhophilin, Rho GTPase binding protein 1	0.010
Fcgbp	Fc fragment of IgG binding protein	0.010
Tulp2	tubby-like protein 2	0.010