IMP
Process View
aldosterone metabolic process
The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "aldosterone metabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.578 | ||
| Phex | phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) | 0.472 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.343 | ||
| Slc12a1 | solute carrier family 12, member 1 | 0.169 | ||
| Nanog | Nanog homeobox | 0.160 | ||
| Msx1 | homeobox, msh-like 1 | 0.156 | ||
| Chrna9 | cholinergic receptor, nicotinic, alpha polypeptide 9 | 0.134 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.104 | ||
| Cyp11a1 | cytochrome P450, family 11, subfamily a, polypeptide 1 | 0.096 | Mouse | |
| Ar | androgen receptor | 0.088 | ||
| Ren1 | renin 1 structural | 0.087 | ||
| Hoxa10 | homeobox A10 | 0.074 | ||
| Slc34a1 | solute carrier family 34 (sodium phosphate), member 1 | 0.072 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.070 | ||
| Runx2 | runt related transcription factor 2 | 0.068 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.068 | ||
| Ptch1 | patched homolog 1 | 0.066 | ||
| Acvr1 | activin A receptor, type 1 | 0.065 | ||
| Itga8 | integrin alpha 8 | 0.053 | ||
| Fshr | follicle stimulating hormone receptor | 0.052 | ||
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.051 | ||
| Pomc | pro-opiomelanocortin-alpha | 0.050 | ||
| Cacna1d | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.046 | ||
| Tbx15 | T-box 15 | 0.045 | ||
| Mc2r | melanocortin 2 receptor | 0.045 | ||
| Lhcgr | luteinizing hormone/choriogonadotropin receptor | 0.042 | ||
| Timp2 | tissue inhibitor of metalloproteinase 2 | 0.040 | ||
| Htt | huntingtin | 0.035 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.035 | ||
| Nostrin | nitric oxide synthase trafficker | 0.032 | ||
| Kcna1 | potassium voltage-gated channel, shaker-related subfamily, member 1 | 0.032 | ||
| Fgf23 | fibroblast growth factor 23 | 0.031 | ||
| Vdr | vitamin D receptor | 0.029 | ||
| Kl | klotho | 0.028 | ||
| Sox9 | SRY-box containing gene 9 | 0.028 | ||
| Agtr1a | angiotensin II receptor, type 1a | 0.028 | ||
| Cyp11b2 | cytochrome P450, family 11, subfamily b, polypeptide 2 | 0.027 | ||
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.026 | ||
| Lum | lumican | 0.026 | ||
| Prrx1 | paired related homeobox 1 | 0.026 | ||
| Star | steroidogenic acute regulatory protein | 0.025 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.025 | ||
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.025 | ||
| Wnt5a | wingless-related MMTV integration site 5A | 0.025 | ||
| Ccrl1 | chemokine (C-C motif) receptor-like 1 | 0.025 | ||
| Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.025 | ||
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.024 | ||
| Ctsk | cathepsin K | 0.023 | ||
| Sema3c | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.023 | ||
| Ctgf | connective tissue growth factor | 0.023 | ||
| Ddx6 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 | 0.021 | ||
| Fstl1 | follistatin-like 1 | 0.021 | ||
| Sema5a | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.021 | ||
| Casr | calcium-sensing receptor | 0.020 | ||
| Cttn | cortactin | 0.020 | ||
| Trap1a | tumor rejection antigen P1A | 0.019 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.019 | ||
| Pde8b | phosphodiesterase 8B | 0.019 | ||
| Wnk4 | WNK lysine deficient protein kinase 4 | 0.018 | ||
| Ihh | Indian hedgehog | 0.018 | ||
| Smad1 | MAD homolog 1 (Drosophila) | 0.018 | ||
| Gnat2 | guanine nucleotide binding protein, alpha transducing 2 | 0.017 | ||
| Angpt1 | angiopoietin 1 | 0.017 | ||
| Col5a2 | collagen, type V, alpha 2 | 0.017 | ||
| Bgn | biglycan | 0.016 | ||
| Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | 0.016 | ||
| Pthlh | parathyroid hormone-like peptide | 0.016 | ||
| Gucy1a3 | guanylate cyclase 1, soluble, alpha 3 | 0.015 | ||
| Kif3a | kinesin family member 3A | 0.015 | ||
| Fam20c | family with sequence similarity 20, member C | 0.015 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.015 | ||
| Pramel6 | preferentially expressed antigen in melanoma like 6 | 0.014 | ||
| Mertk | c-mer proto-oncogene tyrosine kinase | 0.014 | ||
| Lrp2 | low density lipoprotein receptor-related protein 2 | 0.014 | ||
| Pmp22 | peripheral myelin protein 22 | 0.014 | ||
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.014 | ||
| Crh | corticotropin releasing hormone | 0.014 | ||
| C3ar1 | complement component 3a receptor 1 | 0.013 | ||
| Rpl38 | ribosomal protein L38 | 0.013 | ||
| Cga | glycoprotein hormones, alpha subunit | 0.013 | ||
| Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.013 | ||
| Clrn3 | clarin 3 | 0.013 | ||
| Ogn | osteoglycin | 0.013 | ||
| Ltbp3 | latent transforming growth factor beta binding protein 3 | 0.013 | ||
| Upk3a | uroplakin 3A | 0.012 | ||
| Klf12 | Kruppel-like factor 12 | 0.012 | ||
| Adamts1 | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 | 0.012 | ||
| Rhoj | ras homolog gene family, member J | 0.012 | ||
| Eno2 | enolase 2, gamma neuronal | 0.012 | ||
| Islr | immunoglobulin superfamily containing leucine-rich repeat | 0.012 | ||
| Eif2c2 | eukaryotic translation initiation factor 2C, 2 | 0.012 | ||
| Acsm2 | acyl-CoA synthetase medium-chain family member 2 | 0.012 | ||
| Hoxd8 | homeobox D8 | 0.012 | ||
| Npr3 | natriuretic peptide receptor 3 | 0.012 | ||
| Sp1 | trans-acting transcription factor 1 | 0.012 | ||
| Tm4sf1 | transmembrane 4 superfamily member 1 | 0.012 | ||
| Pik3c2g | phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide | 0.012 | ||
| Umod | uromodulin | 0.012 | ||
| Nkx3-1 | NK-3 transcription factor, locus 1 (Drosophila) | 0.012 | ||
| Cacnb2 | calcium channel, voltage-dependent, beta 2 subunit | 0.012 | ||
| Ddr2 | discoidin domain receptor family, member 2 | 0.011 | ||
| Otog | otogelin | 0.011 | ||
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.011 | ||
| Gucy1b3 | guanylate cyclase 1, soluble, beta 3 | 0.011 | ||
| Slc23a2 | solute carrier family 23 (nucleobase transporters), member 2 | 0.011 | ||
| Tgfbr3 | transforming growth factor, beta receptor III | 0.011 | ||
| Ptpn20 | protein tyrosine phosphatase, non-receptor type 20 | 0.011 | ||
| Sparcl1 | SPARC-like 1 | 0.011 | ||
| Ceacam11 | carcinoembryonic antigen-related cell adhesion molecule 11 | 0.011 | ||
| Fgf9 | fibroblast growth factor 9 | 0.011 | ||
| Cdh11 | cadherin 11 | 0.011 | ||
| Omd | osteomodulin | 0.011 | ||
| Stxbp1 | syntaxin binding protein 1 | 0.011 | ||
| Sema3a | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.011 | ||
| Etl4 | enhancer trap locus 4 | 0.011 | ||
| Adam1a | a disintegrin and metallopeptidase domain 1a | 0.010 | ||
| Kap | kidney androgen regulated protein | 0.010 | ||
| F2r | coagulation factor II (thrombin) receptor | 0.010 | ||
| Esr1 | estrogen receptor 1 (alpha) | 0.010 | ||
| Lepr | leptin receptor | 0.010 | ||
| Sntb2 | syntrophin, basic 2 | 0.010 | ||
| Uchl1 | ubiquitin carboxy-terminal hydrolase L1 | 0.010 |