IMP
Process View
long term synaptic depression
A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "long term synaptic depression"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Gria2 | glutamate receptor, ionotropic, AMPA2 (alpha 2) | 0.978 | Mouse | |
| Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.971 | ||
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.728 | ||
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.672 | ||
| Gria1 | glutamate receptor, ionotropic, AMPA1 (alpha 1) | 0.395 | ||
| Akt1 | thymoma viral proto-oncogene 1 | 0.378 | Fly | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.364 | ||
| Grin2a | glutamate receptor, ionotropic, NMDA2A (epsilon 1) | 0.310 | ||
| Drd2 | dopamine receptor D2 | 0.249 | ||
| Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.249 | ||
| Kl | klotho | 0.165 | ||
| Grik4 | glutamate receptor, ionotropic, kainate 4 | 0.151 | ||
| Dlgap1 | discs, large (Drosophila) homolog-associated protein 1 | 0.137 | ||
| Sstr4 | somatostatin receptor 4 | 0.116 | ||
| Csmd1 | CUB and Sushi multiple domains 1 | 0.104 | ||
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.097 | ||
| Htr1a | 5-hydroxytryptamine (serotonin) receptor 1A | 0.089 | Mouse | |
| Gria4 | glutamate receptor, ionotropic, AMPA4 (alpha 4) | 0.086 | Mouse | |
| Shc3 | src homology 2 domain-containing transforming protein C3 | 0.085 | ||
| Grid1 | glutamate receptor, ionotropic, delta 1 | 0.085 | ||
| ND6 | NADH dehydrogenase subunit 6 | 0.082 | ||
| Grik2 | glutamate receptor, ionotropic, kainate 2 (beta 2) | 0.080 | Mouse | |
| Mitf | microphthalmia-associated transcription factor | 0.079 | ||
| Kcna4 | potassium voltage-gated channel, shaker-related subfamily, member 4 | 0.076 | ||
| Camk2a | calcium/calmodulin-dependent protein kinase II alpha | 0.075 | ||
| Cdh6 | cadherin 6 | 0.071 | ||
| Hrk | harakiri, BCL2 interacting protein (contains only BH3 domain) | 0.071 | ||
| Adrb2 | adrenergic receptor, beta 2 | 0.069 | Mouse | |
| Nrg3 | neuregulin 3 | 0.068 | ||
| Chrm1 | cholinergic receptor, muscarinic 1, CNS | 0.067 | ||
| Cckbr | cholecystokinin B receptor | 0.066 | ||
| Srebf2 | sterol regulatory element binding factor 2 | 0.058 | ||
| Stx1a | syntaxin 1A (brain) | 0.058 | ||
| Grip1 | glutamate receptor interacting protein 1 | 0.058 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.056 | ||
| Cacng2 | calcium channel, voltage-dependent, gamma subunit 2 | 0.053 | ||
| Neto1 | neuropilin (NRP) and tolloid (TLL)-like 1 | 0.051 | ||
| Nxph1 | neurexophilin 1 | 0.048 | ||
| Gabra2 | gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 | 0.047 | ||
| Arpc4 | actin related protein 2/3 complex, subunit 4 | 0.046 | ||
| Sstr1 | somatostatin receptor 1 | 0.046 | ||
| Grin2b | glutamate receptor, ionotropic, NMDA2B (epsilon 2) | 0.045 | ||
| Lyst | lysosomal trafficking regulator | 0.045 | ||
| Cnr1 | cannabinoid receptor 1 (brain) | 0.041 | ||
| Adrb1 | adrenergic receptor, beta 1 | 0.040 | Mouse | |
| Gria3 | glutamate receptor, ionotropic, AMPA3 (alpha 3) | 0.039 | Mouse | |
| Npy2r | neuropeptide Y receptor Y2 | 0.039 | ||
| Kcnj6 | potassium inwardly-rectifying channel, subfamily J, member 6 | 0.039 | ||
| Col25a1 | collagen, type XXV, alpha 1 | 0.037 | ||
| Mlf2 | myeloid leukemia factor 2 | 0.034 | ||
| F11r | F11 receptor | 0.033 | ||
| Crhr1 | corticotropin releasing hormone receptor 1 | 0.032 | ||
| Bdnf | brain derived neurotrophic factor | 0.032 | ||
| Rasgrp1 | RAS guanyl releasing protein 1 | 0.031 | ||
| Ptpn5 | protein tyrosine phosphatase, non-receptor type 5 | 0.031 | ||
| Accn1 | amiloride-sensitive cation channel 1, neuronal (degenerin) | 0.030 | ||
| B3gat1 | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | 0.030 | ||
| Nphp4 | nephronophthisis 4 (juvenile) homolog (human) | 0.029 | ||
| Htr4 | 5 hydroxytryptamine (serotonin) receptor 4 | 0.029 | Mouse | |
| Lhx6 | LIM homeobox protein 6 | 0.029 | ||
| Cntn3 | contactin 3 | 0.028 | ||
| Syn2 | synapsin II | 0.027 | ||
| Plcg1 | phospholipase C, gamma 1 | 0.027 | ||
| Kcna2 | potassium voltage-gated channel, shaker-related subfamily, member 2 | 0.027 | ||
| Gabrg3 | gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3 | 0.027 | ||
| Htr1d | 5-hydroxytryptamine (serotonin) receptor 1D | 0.027 | Mouse | |
| Tyr | tyrosinase | 0.026 | ||
| Trpc5 | transient receptor potential cation channel, subfamily C, member 5 | 0.025 | ||
| Pde10a | phosphodiesterase 10A | 0.025 | ||
| Epha6 | Eph receptor A6 | 0.025 | ||
| Grm2 | glutamate receptor, metabotropic 2 | 0.025 | ||
| Npy5r | neuropeptide Y receptor Y5 | 0.024 | ||
| Hrh1 | histamine receptor H1 | 0.024 | ||
| Rac1 | RAS-related C3 botulinum substrate 1 | 0.024 | ||
| Gorasp2 | golgi reassembly stacking protein 2 | 0.024 | ||
| Cntn4 | contactin 4 | 0.023 | ||
| Lag3 | lymphocyte-activation gene 3 | 0.023 | ||
| Sct | secretin | 0.022 | ||
| Cdh10 | cadherin 10 | 0.021 | ||
| Slc32a1 | solute carrier family 32 (GABA vesicular transporter), member 1 | 0.021 | ||
| Lrrc59 | leucine rich repeat containing 59 | 0.021 | ||
| Htr7 | 5-hydroxytryptamine (serotonin) receptor 7 | 0.021 | ||
| Cdh8 | cadherin 8 | 0.021 | ||
| Prkaca | protein kinase, cAMP dependent, catalytic, alpha | 0.020 | ||
| Srcin1 | SRC kinase signaling inhibitor 1 | 0.020 | ||
| Cabp7 | calcium binding protein 7 | 0.020 | ||
| Mb | myoglobin | 0.020 | ||
| Slc35b1 | solute carrier family 35, member B1 | 0.020 | ||
| Slc39a7 | solute carrier family 39 (zinc transporter), member 7 | 0.019 | ||
| Dlg2 | discs, large homolog 2 (Drosophila) | 0.019 | ||
| Pcsk2 | proprotein convertase subtilisin/kexin type 2 | 0.019 | ||
| Prkce | protein kinase C, epsilon | 0.019 | ||
| Upp2 | uridine phosphorylase 2 | 0.019 | ||
| Cacng8 | calcium channel, voltage-dependent, gamma subunit 8 | 0.018 | ||
| Csnk1g2 | casein kinase 1, gamma 2 | 0.018 | ||
| Kcnc4 | potassium voltage gated channel, Shaw-related subfamily, member 4 | 0.018 | ||
| Hcrt | hypocretin | 0.018 | ||
| Pdyn | prodynorphin | 0.018 | ||
| Lrp1b | low density lipoprotein-related protein 1B (deleted in tumors) | 0.017 | ||
| Mas1 | MAS1 oncogene | 0.017 | ||
| Trpv1 | transient receptor potential cation channel, subfamily V, member 1 | 0.017 | ||
| Aamp | angio-associated migratory protein | 0.017 | ||
| Kcnd2 | potassium voltage-gated channel, Shal-related family, member 2 | 0.017 | ||
| Ppp1r1b | protein phosphatase 1, regulatory (inhibitor) subunit 1B | 0.017 | ||
| Car10 | carbonic anhydrase 10 | 0.017 | ||
| Hrh3 | histamine receptor H3 | 0.017 | ||
| Shank3 | SH3/ankyrin domain gene 3 | 0.017 | ||
| Gast | gastrin | 0.016 | ||
| Syt6 | synaptotagmin VI | 0.016 | ||
| Gjd2 | gap junction protein, delta 2 | 0.016 | ||
| Rp1 | retinitis pigmentosa 1 (human) | 0.016 | ||
| Vip | vasoactive intestinal polypeptide | 0.016 | ||
| Sst | somatostatin | 0.016 | ||
| Odz1 | odd Oz/ten-m homolog 1 (Drosophila) | 0.016 | ||
| Pax4 | paired box gene 4 | 0.015 | ||
| Grm1 | glutamate receptor, metabotropic 1 | 0.015 | ||
| Cer1 | cerberus 1 homolog (Xenopus laevis) | 0.015 | ||
| Mapkapk2 | MAP kinase-activated protein kinase 2 | 0.015 | ||
| Gad2 | glutamic acid decarboxylase 2 | 0.015 | ||
| Elf1 | E74-like factor 1 | 0.015 | ||
| Cux2 | cut-like homeobox 2 | 0.015 | ||
| Nhedc2 | Na+/H+ exchanger domain containing 2 | 0.015 | ||
| Unc5c | unc-5 homolog C (C. elegans) | 0.015 | ||
| Sgip1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.015 | ||
| Egr3 | early growth response 3 | 0.014 | ||
| Kcnk3 | potassium channel, subfamily K, member 3 | 0.014 | ||
| Ryr3 | ryanodine receptor 3 | 0.014 | ||
| Fgf4 | fibroblast growth factor 4 | 0.014 | ||
| Gabrb1 | gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 | 0.014 | ||
| Clcnka | chloride channel Ka | 0.014 | ||
| Has1 | hyaluronan synthase1 | 0.013 | ||
| Slc6a4 | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 0.013 | ||
| Galr2 | galanin receptor 2 | 0.013 | ||
| Chrna7 | cholinergic receptor, nicotinic, alpha polypeptide 7 | 0.013 | ||
| Capzb | capping protein (actin filament) muscle Z-line, beta | 0.013 | ||
| Oprk1 | opioid receptor, kappa 1 | 0.013 | ||
| Lamp2 | lysosomal-associated membrane protein 2 | 0.013 | ||
| Jam3 | junction adhesion molecule 3 | 0.013 | ||
| Khdc1b | KH domain containing 1B | 0.013 | ||
| Slit1 | slit homolog 1 (Drosophila) | 0.013 | ||
| Akt2 | thymoma viral proto-oncogene 2 | 0.012 | Fly | |
| Crtac1 | cartilage acidic protein 1 | 0.012 | ||
| Nrip3 | nuclear receptor interacting protein 3 | 0.012 | ||
| Gpr3 | G-protein coupled receptor 3 | 0.012 | ||
| Ndst3 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 | 0.012 | ||
| Kcnj3 | potassium inwardly-rectifying channel, subfamily J, member 3 | 0.012 | ||
| Tnfrsf8 | tumor necrosis factor receptor superfamily, member 8 | 0.012 | ||
| Kcnd3 | potassium voltage-gated channel, Shal-related family, member 3 | 0.012 | ||
| Kcnq2 | potassium voltage-gated channel, subfamily Q, member 2 | 0.012 | ||
| Efna5 | ephrin A5 | 0.012 | ||
| Adra2b | adrenergic receptor, alpha 2b | 0.012 | Mouse | |
| 3110079O15Rik | RIKEN cDNA 3110079O15 gene | 0.012 | ||
| Gabra1 | gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 | 0.012 | ||
| Hcn4 | hyperpolarization-activated, cyclic nucleotide-gated K+ 4 | 0.012 | ||
| Mllt1 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 | 0.012 | ||
| Rgs4 | regulator of G-protein signaling 4 | 0.011 | ||
| Mapkap1 | mitogen-activated protein kinase associated protein 1 | 0.011 | ||
| Gpr26 | G protein-coupled receptor 26 | 0.011 | ||
| Sebox | SEBOX homeobox | 0.011 | ||
| Dmp1 | dentin matrix protein 1 | 0.011 | ||
| Sema5b | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B | 0.011 | ||
| Slc6a11 | solute carrier family 6 (neurotransmitter transporter, GABA), member 11 | 0.011 | ||
| Baalc | brain and acute leukemia, cytoplasmic | 0.011 | ||
| Kcnab1 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | 0.011 | ||
| Cacng3 | calcium channel, voltage-dependent, gamma subunit 3 | 0.011 | ||
| Epha8 | Eph receptor A8 | 0.011 | ||
| Rit2 | Ras-like without CAAX 2 | 0.011 | ||
| Stx12 | syntaxin 12 | 0.011 | ||
| Atp2b2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.011 | ||
| Plcb1 | phospholipase C, beta 1 | 0.011 | ||
| Mmp24 | matrix metallopeptidase 24 | 0.011 | ||
| Kifc2 | kinesin family member C2 | 0.011 | ||
| Grik3 | glutamate receptor, ionotropic, kainate 3 | 0.011 | Mouse | |
| Grm8 | glutamate receptor, metabotropic 8 | 0.011 | ||
| Rbpjl | recombination signal binding protein for immunoglobulin kappa J region-like | 0.011 | ||
| Itga2 | integrin alpha 2 | 0.010 | ||
| D3Bwg0562e | DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed | 0.010 | ||
| Hs6st3 | heparan sulfate 6-O-sulfotransferase 3 | 0.010 | ||
| Il12b | interleukin 12b | 0.010 | ||
| Scube1 | signal peptide, CUB domain, EGF-like 1 | 0.010 | ||
| Hivep2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.010 | ||
| Kcnt1 | potassium channel, subfamily T, member 1 | 0.010 | ||
| Nos1 | nitric oxide synthase 1, neuronal | 0.010 | ||
| Kcng3 | potassium voltage-gated channel, subfamily G, member 3 | 0.010 | ||
| Tacr1 | tachykinin receptor 1 | 0.010 | ||
| Rnf112 | ring finger protein 112 | 0.010 | ||
| Grik1 | glutamate receptor, ionotropic, kainate 1 | 0.010 | ||
| Oprd1 | opioid receptor, delta 1 | 0.010 |