Process View
A cell cycle checkpoint that originates from the mitotic or meiotic spindle.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "spindle checkpoint"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Ccnb1 | cyclin B1 | 0.753 | Human | |
| Cdk1 | cyclin-dependent kinase 1 | 0.671 | ||
| Ccnb2 | cyclin B2 | 0.627 | ||
| Prc1 | protein regulator of cytokinesis 1 | 0.598 | ||
| Kif20a | kinesin family member 20A | 0.499 | ||
| Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.464 | ||
| Kif22 | kinesin family member 22 | 0.462 | ||
| Bub1 | budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) | 0.200 | ||
| Dlgap5 | discs, large (Drosophila) homolog-associated protein 5 | 0.185 | ||
| Kif2c | kinesin family member 2C | 0.171 | ||
| Aurka | aurora kinase A | 0.169 | ||
| Spag5 | sperm associated antigen 5 | 0.152 | ||
| Brca2 | breast cancer 2 | 0.140 | ||
| Trp53 | transformation related protein 53 | 0.137 | ||
| Ccna2 | cyclin A2 | 0.126 | ||
| Mki67 | antigen identified by monoclonal antibody Ki 67 | 0.121 | ||
| Rnf2 | ring finger protein 2 | 0.118 | ||
| Trim59 | tripartite motif-containing 59 | 0.116 | ||
| Brca1 | breast cancer 1 | 0.115 | ||
| Cdca8 | cell division cycle associated 8 | 0.114 | ||
| Kdm2b | lysine (K)-specific demethylase 2B | 0.099 | ||
| Ckap2 | cytoskeleton associated protein 2 | 0.098 | ||
| C330027C09Rik | RIKEN cDNA C330027C09 gene | 0.094 | ||
| Cdkn3 | cyclin-dependent kinase inhibitor 3 | 0.089 | ||
| Cenpe | centromere protein E | 0.089 | ||
| Sgol2 | shugoshin-like 2 (S. pombe) | 0.087 | ||
| Ube2c | ubiquitin-conjugating enzyme E2C | 0.079 | ||
| Birc5 | baculoviral IAP repeat-containing 5 | 0.072 | Human | |
| Nek2 | NIMA (never in mitosis gene a)-related expressed kinase 2 | 0.071 | ||
| Hmmr | hyaluronan mediated motility receptor (RHAMM) | 0.071 | ||
| Ccnf | cyclin F | 0.065 | ||
| Ttk | Ttk protein kinase | 0.065 | Yeast Fly | |
| Top2a | topoisomerase (DNA) II alpha | 0.061 | ||
| Cdc20 | cell division cycle 20 homolog (S. cerevisiae) | 0.060 | Yeast | |
| Cks2 | CDC28 protein kinase regulatory subunit 2 | 0.059 | ||
| Dtl | denticleless homolog (Drosophila) | 0.059 | ||
| Kif4 | kinesin family member 4 | 0.058 | ||
| Kif23 | kinesin family member 23 | 0.057 | ||
| Kif11 | kinesin family member 11 | 0.056 | ||
| Cdc25c | cell division cycle 25 homolog C (S. pombe) | 0.056 | ||
| Ncapg | non-SMC condensin I complex, subunit G | 0.049 | ||
| Cenpk | centromere protein K | 0.047 | ||
| Ect2 | ect2 oncogene | 0.047 | ||
| Rpgrip1l | Rpgrip1-like | 0.045 | ||
| Ooep | oocyte expressed protein homolog (dog) | 0.041 | ||
| Lrrk2 | leucine-rich repeat kinase 2 | 0.039 | ||
| Mis18bp1 | MIS18 binding protein 1 | 0.034 | ||
| Racgap1 | Rac GTPase-activating protein 1 | 0.033 | ||
| Bub1b | budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) | 0.032 | Fly | |
| Aurkb | aurora kinase B | 0.030 | ||
| Asf1b | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.028 | ||
| Cep55 | centrosomal protein 55 | 0.028 | ||
| Ube2t | ubiquitin-conjugating enzyme E2T (putative) | 0.027 | ||
| Dna2 | DNA replication helicase 2 homolog (yeast) | 0.027 | ||
| Ccdc99 | coiled-coil domain containing 99 | 0.027 | ||
| Skp1a | S-phase kinase-associated protein 1A | 0.025 | ||
| Melk | maternal embryonic leucine zipper kinase | 0.025 | ||
| Anln | anillin, actin binding protein | 0.025 | ||
| 2810417H13Rik | RIKEN cDNA 2810417H13 gene | 0.025 | ||
| Ndc80 | NDC80 homolog, kinetochore complex component (S. cerevisiae) | 0.024 | ||
| Axin1 | axin 1 | 0.024 | ||
| Smc4 | structural maintenance of chromosomes 4 | 0.024 | ||
| Crk | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.023 | ||
| Blm | Bloom syndrome, RecQ helicase-like | 0.023 | ||
| Plk4 | polo-like kinase 4 (Drosophila) | 0.022 | ||
| Cenpa | centromere protein A | 0.021 | ||
| Trp63 | transformation related protein 63 | 0.019 | ||
| Lin28a | lin-28 homolog A (C. elegans) | 0.018 | ||
| Hist1h2bm | histone cluster 1, H2bm | 0.018 | ||
| Nasp | nuclear autoantigenic sperm protein (histone-binding) | 0.018 | ||
| Sgol1 | shugoshin-like 1 (S. pombe) | 0.018 | ||
| Cdk4 | cyclin-dependent kinase 4 | 0.018 | ||
| Rad51ap1 | RAD51 associated protein 1 | 0.018 | ||
| Ccne2 | cyclin E2 | 0.016 | ||
| Cbx1 | chromobox homolog 1 (Drosophila HP1 beta) | 0.016 | ||
| Tacc3 | transforming, acidic coiled-coil containing protein 3 | 0.016 | ||
| Gtse1 | G two S phase expressed protein 1 | 0.015 | ||
| Sass6 | spindle assembly 6 homolog (C. elegans) | 0.015 | ||
| Hmgb2 | high mobility group box 2 | 0.014 | ||
| E2f8 | E2F transcription factor 8 | 0.014 | ||
| Gsg2 | germ cell-specific gene 2 | 0.014 | Human | |
| Cops7b | COP9 (constitutive photomorphogenic) homolog, subunit 7b (Arabidopsis thaliana) | 0.014 | ||
| Stil | Scl/Tal1 interrupting locus | 0.014 | ||
| Depdc1a | DEP domain containing 1a | 0.013 | ||
| Rbl1 | retinoblastoma-like 1 (p107) | 0.013 | ||
| Trip13 | thyroid hormone receptor interactor 13 | 0.013 | ||
| 4632434I11Rik | RIKEN cDNA 4632434I11 gene | 0.012 | ||
| H2afz | H2A histone family, member Z | 0.012 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.011 | ||
| Lin9 | lin-9 homolog (C. elegans) | 0.011 | ||
| Scaf4 | SR-related CTD-associated factor 4 | 0.010 | ||
| Mns1 | meiosis-specific nuclear structural protein 1 | 0.010 | ||
| Pot1a | protection of telomeres 1A | 0.010 | ||
| Zfp598 | zinc finger protein 598 | 0.010 | ||
| Carm1 | coactivator-associated arginine methyltransferase 1 | 0.010 | ||
| Pgr | progesterone receptor | 0.010 | ||
| Csnk2a1 | casein kinase 2, alpha 1 polypeptide | 0.010 | Human | |
| Cenpn | centromere protein N | 0.010 |