IMP
Process View
g2 dna damage checkpoint
A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase in the cell cycle in response to DNA damage.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "g2 dna damage checkpoint"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Brca1 | breast cancer 1 | 0.848 | Human | |
| Cdk4 | cyclin-dependent kinase 4 | 0.536 | ||
| Trp53 | transformation related protein 53 | 0.397 | ||
| Brca2 | breast cancer 2 | 0.217 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.140 | ||
| Rb1 | retinoblastoma 1 | 0.107 | ||
| Nbn | nibrin | 0.078 | ||
| E2f1 | E2F transcription factor 1 | 0.073 | ||
| Hells | helicase, lymphoid specific | 0.048 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.044 | ||
| Lsm2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.042 | ||
| Atm | ataxia telangiectasia mutated homolog (human) | 0.042 | Human Fly | |
| Stag1 | stromal antigen 1 | 0.038 | ||
| H2afx | H2A histone family, member X | 0.030 | ||
| Mcm5 | minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 0.028 | ||
| Pten | phosphatase and tensin homolog | 0.026 | ||
| Ezh2 | enhancer of zeste homolog 2 (Drosophila) | 0.025 | ||
| Cops4 | COP9 (constitutive photomorphogenic) homolog, subunit 4 (Arabidopsis thaliana) | 0.022 | ||
| Cops6 | COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana) | 0.019 | ||
| Ddx46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.019 | ||
| Mybl2 | myeloblastosis oncogene-like 2 | 0.019 | ||
| Nasp | nuclear autoantigenic sperm protein (histone-binding) | 0.018 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.018 | ||
| Cops2 | COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana) | 0.017 | ||
| Suz12 | suppressor of zeste 12 homolog (Drosophila) | 0.016 | ||
| Mcm2 | minichromosome maintenance deficient 2 mitotin (S. cerevisiae) | 0.016 | ||
| Ccna2 | cyclin A2 | 0.015 | ||
| Prc1 | protein regulator of cytokinesis 1 | 0.015 | ||
| Dtl | denticleless homolog (Drosophila) | 0.014 | Human Zebrafish | |
| Ruvbl2 | RuvB-like protein 2 | 0.014 | ||
| Rbbp5 | retinoblastoma binding protein 5 | 0.014 | ||
| Elavl1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 0.014 | ||
| Tial1 | Tia1 cytotoxic granule-associated RNA binding protein-like 1 | 0.014 | ||
| Ash2l | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.014 | ||
| Mre11a | meiotic recombination 11 homolog A (S. cerevisiae) | 0.014 | ||
| Aurka | aurora kinase A | 0.014 | ||
| Mcm3 | minichromosome maintenance deficient 3 (S. cerevisiae) | 0.013 | Fly | |
| Ccne1 | cyclin E1 | 0.013 | ||
| Ldha | lactate dehydrogenase A | 0.013 | ||
| Ccnb1 | cyclin B1 | 0.013 | ||
| Phc2 | polyhomeotic-like 2 (Drosophila) | 0.013 | ||
| Cdca7 | cell division cycle associated 7 | 0.012 | ||
| Hnrnpr | heterogeneous nuclear ribonucleoprotein R | 0.012 | ||
| Egr2 | early growth response 2 | 0.012 | ||
| Smc2 | structural maintenance of chromosomes 2 | 0.011 | ||
| Men1 | multiple endocrine neoplasia 1 | 0.011 | ||
| Cdc45 | cell division cycle 45 homolog (S. cerevisiae) | 0.011 | Fly | |
| Tcf19 | transcription factor 19 | 0.011 | ||
| Tdp2 | tyrosyl-DNA phosphodiesterase 2 | 0.011 | ||
| Cdca5 | cell division cycle associated 5 | 0.010 |