Process View
The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "cd4 positive cd25 positive alpha beta regulatory t cell differentiation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Ikzf1 | IKAROS family zinc finger 1 | 0.999 | ||
| Tcra | T-cell receptor alpha chain | 0.996 | ||
| Lat | linker for activation of T cells | 0.995 | ||
| Foxn1 | forkhead box N1 | 0.975 | ||
| Ptprc | protein tyrosine phosphatase, receptor type, C | 0.958 | ||
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.922 | ||
| Rag1 | recombination activating gene 1 | 0.921 | ||
| Cd247 | CD247 antigen | 0.894 | ||
| Ifng | interferon gamma | 0.842 | ||
| Rag2 | recombination activating gene 2 | 0.825 | ||
| Fyn | Fyn proto-oncogene | 0.782 | ||
| Lck | lymphocyte protein tyrosine kinase | 0.738 | ||
| Tnf | tumor necrosis factor | 0.690 | ||
| Foxp3 | forkhead box P3 | 0.649 | ||
| Il2 | interleukin 2 | 0.615 | ||
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.560 | ||
| Tcrd | T-cell receptor delta chain | 0.469 | ||
| Prf1 | perforin 1 (pore forming protein) | 0.401 | ||
| Cd19 | CD19 antigen | 0.335 | ||
| Cd79a | CD79A antigen (immunoglobulin-associated alpha) | 0.326 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.314 | ||
| Trp53 | transformation related protein 53 | 0.307 | ||
| Il4 | interleukin 4 | 0.181 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.176 | ||
| Jak3 | Janus kinase 3 | 0.163 | ||
| Hdac7 | histone deacetylase 7 | 0.159 | ||
| Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.137 | ||
| Il10 | interleukin 10 | 0.103 | ||
| Zap70 | zeta-chain (TCR) associated protein kinase | 0.100 | ||
| Igh | immunoglobulin heavy chain complex | 0.096 | ||
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.090 | ||
| Cd28 | CD28 antigen | 0.085 | ||
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.076 | ||
| Il15 | interleukin 15 | 0.073 | ||
| Il2rb | interleukin 2 receptor, beta chain | 0.067 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.067 | ||
| Foxp1 | forkhead box P1 | 0.065 | Mouse | |
| Il7r | interleukin 7 receptor | 0.057 | ||
| Arid1a | AT rich interactive domain 1A (SWI-like) | 0.056 | ||
| Aire | autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) | 0.056 | ||
| B2m | beta-2 microglobulin | 0.056 | ||
| Mll5 | myeloid/lymphoid or mixed-lineage leukemia 5 | 0.051 | ||
| Ttc7 | tetratricopeptide repeat domain 7 | 0.051 | ||
| H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | 0.046 | ||
| Card11 | caspase recruitment domain family, member 11 | 0.046 | ||
| Mll1 | myeloid/lymphoid or mixed-lineage leukemia 1 | 0.045 | ||
| Il2rg | interleukin 2 receptor, gamma chain | 0.043 | ||
| Lta | lymphotoxin A | 0.039 | ||
| Tnfsf11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.034 | ||
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.032 | ||
| Thra | thyroid hormone receptor alpha | 0.029 | ||
| Socs1 | suppressor of cytokine signaling 1 | 0.028 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.028 | ||
| Sin3a | transcriptional regulator, SIN3A (yeast) | 0.026 | ||
| Zfp362 | zinc finger protein 362 | 0.026 | ||
| Tnrc6c | trinucleotide repeat containing 6C | 0.026 | ||
| Cd4 | CD4 antigen | 0.026 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.025 | ||
| Ccr7 | chemokine (C-C motif) receptor 7 | 0.025 | ||
| Hcst | hematopoietic cell signal transducer | 0.020 | ||
| Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.020 | ||
| Il6st | interleukin 6 signal transducer | 0.019 | ||
| Ash1l | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.018 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.018 | ||
| Apc | adenomatosis polyposis coli | 0.018 | ||
| Stat5a | signal transducer and activator of transcription 5A | 0.017 | ||
| Jak1 | Janus kinase 1 | 0.017 | ||
| Pten | phosphatase and tensin homolog | 0.016 | ||
| Bptf | bromodomain PHD finger transcription factor | 0.016 | ||
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.015 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.015 | ||
| Mll3 | myeloid/lymphoid or mixed-lineage leukemia 3 | 0.014 | ||
| Ciita | class II transactivator | 0.014 | ||
| Itk | IL2-inducible T-cell kinase | 0.013 | ||
| Batf3 | basic leucine zipper transcription factor, ATF-like 3 | 0.013 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.013 | ||
| Cic | capicua homolog (Drosophila) | 0.013 | ||
| Lyst | lysosomal trafficking regulator | 0.012 | ||
| Zc3h11a | zinc finger CCCH type containing 11A | 0.012 | ||
| Igf2bp1 | insulin-like growth factor 2 mRNA binding protein 1 | 0.012 | ||
| Hhex | hematopoietically expressed homeobox | 0.012 | ||
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.012 | ||
| Kit | kit oncogene | 0.012 | ||
| Ltb | lymphotoxin B | 0.012 | ||
| Crebbp | CREB binding protein | 0.012 | ||
| Arrdc3 | arrestin domain containing 3 | 0.012 | ||
| Runx1 | runt related transcription factor 1 | 0.011 | ||
| Tnfsf14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.011 | ||
| Smad1 | MAD homolog 1 (Drosophila) | 0.011 | ||
| Stim1 | stromal interaction molecule 1 | 0.011 | ||
| Hr | hairless | 0.011 | ||
| Plk1 | polo-like kinase 1 (Drosophila) | 0.011 | ||
| Batf | basic leucine zipper transcription factor, ATF-like | 0.010 | ||
| Tcf4 | transcription factor 4 | 0.010 | ||
| Nkx2-3 | NK2 transcription factor related, locus 3 (Drosophila) | 0.010 | ||
| Zbtb20 | zinc finger and BTB domain containing 20 | 0.010 | ||
| Clcnka | chloride channel Ka | 0.010 | ||
| Prr12 | proline rich 12 | 0.010 | ||
| Cxcr2 | chemokine (C-X-C motif) receptor 2 | 0.010 |