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Rattus norvegicus

3 genes annotated in rat

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activation of protein kinase b activity

GO:0032148

Any process that initiates the activity of the inactive enzyme protein kinase B.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "activation of protein kinase b activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "activation of protein kinase b activity" (in gray)

Name	Description	Probability	Func Analog Organism
Sirpa	signal-regulatory protein alpha	0.206
Fmnl1	formin-like 1	0.142
Gna12	guanine nucleotide binding protein (G protein) alpha 12	0.141
Ptprc	protein tyrosine phosphatase, receptor type, C	0.081
Fam70b	family with sequence similarity 70, member B	0.081
Dock8	dedicator of cytokinesis 8	0.079
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.077
Eef2	eukaryotic translation elongation factor 2	0.077
Rab1b	RAB1B, member RAS oncogene family	0.077
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.071	Rat
Cops7a	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)	0.069
Fgfr1	Fibroblast growth factor receptor 1	0.066
Adar	adenosine deaminase, RNA-specific	0.062
Inpp5d	inositol polyphosphate-5-phosphatase D	0.058
Gnb2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.058
Hist1h1a	histone cluster 1, H1a	0.049
Tgfb1	transforming growth factor, beta 1	0.044
Il1b	interleukin 1 beta	0.041
Nras	neuroblastoma ras oncogene	0.041
Syngr2	synaptogyrin 2	0.041
Il2rb	interleukin 2 receptor, beta	0.041
Hk1	hexokinase 1	0.040
Stat6	signal transducer and activator of transcription 6	0.040
Cd247	Cd247 molecule	0.037
Cd83	CD83 molecule	0.037
Il18	interleukin 18	0.035
Cd37	CD37 molecule	0.035
Ptafr	platelet-activating factor receptor	0.034
Smad7	SMAD family member 7	0.034
Mobkl2a	MOB1, Mps One Binder kinase activator-like 2A (yeast)	0.032
Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	0.031
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.031
Vav1	vav 1 guanine nucleotide exchange factor	0.030
Ptpro	protein tyrosine phosphatase, receptor type, O	0.030
Usf2	upstream transcription factor 2, c-fos interacting	0.030
Gja1	gap junction protein, alpha 1	0.029
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.029
Mprip	myosin phosphatase Rho interacting protein	0.029
Myh9	myosin, heavy chain 9, non-muscle	0.029
Sptbn2	spectrin, beta, non-erythrocytic 2	0.029
Bok	BCL2-related ovarian killer	0.028
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.028
Sgta	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	0.027
Epn2	epsin 2	0.027
Rgs14	regulator of G-protein signaling 14	0.027
Cx3cl1	chemokine (C-X3-C motif) ligand 1	0.027
Arf5	ADP-ribosylation factor 5	0.027
Cyfip2	cytoplasmic FMR1 interacting protein 2	0.026
Olr1469	olfactory receptor Olr1469	0.026
Lphn1	latrophilin 1	0.026
Fgfr2	fibroblast growth factor receptor 2	0.025
Casp1	caspase 1	0.024
Prkcd	protein kinase C, delta	0.024	Rat
Icos	inducible T-cell co-stimulator	0.024
Csnk1g2	casein kinase 1, gamma 2	0.024
RGD1311493	similar to CG13379-PA	0.024
Cd4	Cd4 molecule	0.024
Itpr3	inositol 1,4,5-triphosphate receptor, type 3	0.023
Ocln	occludin	0.023
Cyth1	cytohesin 1	0.023
Il2rg	interleukin 2 receptor, gamma	0.023
Ly86	lymphocyte antigen 86	0.022
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.022
Foxg1	forkhead box G1	0.022
Tgfbr2	transforming growth factor, beta receptor II	0.022
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.022
Sema6b	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	0.022
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.022
Cmtm6	CKLF-like MARVEL transmembrane domain containing 6	0.022
St8sia3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	0.022
Ddr1	discoidin domain receptor tyrosine kinase 1	0.022
LOC100364500	RT1 class I, locus CE11-like	0.022
Olr857	olfactory receptor 857	0.021
Hck	hemopoietic cell kinase	0.021	Rat
Faah	fatty acid amide hydrolase	0.021
Dlgap4	discs, large homolog-associated protein 4 (Drosophila)	0.021
Bid	BH3 interacting domain death agonist	0.021
Cnksr2	connector enhancer of kinase suppressor of Ras 2	0.021
Atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.020
Myo1g	myosin IG	0.020
Syk	spleen tyrosine kinase	0.020
Ttc3	tetratricopeptide repeat domain 3	0.020
Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.020	Rat
Cga	glycoprotein hormones, alpha polypeptide	0.020
Ccnd3	cyclin D3	0.020
Olr1701	olfactory receptor 1701	0.019
Ptk2b	PTK2B protein tyrosine kinase 2 beta	0.019
Arl5c	ADP-ribosylation factor-like 5C	0.019
Fusip1	FUS interacting protein (serine-arginine rich) 1	0.019
Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.019
Sbk1	SH3-binding domain kinase 1	0.019
Adrbk1	adrenergic, beta, receptor kinase 1	0.019
Arhgap27	Rho GTPase activating protein 27	0.019
Cfp	complement factor properdin	0.019
Grin2b	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.018
Irs1	insulin receptor substrate 1	0.018
Rasa2	RAS p21 protein activator 2	0.018
Calcrl	calcitonin receptor-like	0.018
Cd3g	CD3 molecule, gamma	0.018
Lmo2	LIM domain only 2	0.018
Gabrp	gamma-aminobutyric acid (GABA-A) receptor, pi	0.018
Cxcr3	chemokine (C-X-C motif) receptor 3	0.018
Dgkg	diacylglycerol kinase, gamma	0.018
Ubtf	upstream binding transcription factor, RNA polymerase I	0.017
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.017
Gcn1l1	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	0.017
Ralgds	ral guanine nucleotide dissociation stimulator	0.017
Clcn4-2	chloride channel 4-2	0.017
Parp14	poly (ADP-ribose) polymerase family, member 14	0.017
Ctf1	cardiotrophin 1	0.017
Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4	0.017
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.017
Shc2	SHC (Src homology 2 domain containing) transforming protein 2	0.017
Cd5	Cd5 molecule	0.017
Accn1	amiloride-sensitive cation channel 1, neuronal	0.017
Sostdc1	sclerostin domain containing 1	0.017
Foxq1	forkhead box Q1	0.017
RGD1562618	similar to RIKEN cDNA 6030419C18 gene	0.016
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.016
Cplx2	complexin 2	0.016
Plcg2	phospholipase C, gamma 2	0.016
Dag1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	0.016
Syt17	synaptotagmin XVII	0.016
Arnt	aryl hydrocarbon receptor nuclear translocator	0.016
Znf503	zinc finger protein 503	0.016
Ptprs	protein tyrosine phosphatase, receptor type, S	0.016
Arpp21	cAMP-regulated phosphoprotein 21	0.016
Klhl6	kelch-like 6 (Drosophila)	0.016
Arhgap25	Rho GTPase activating protein 25	0.016
Pik3r2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.016
LOC207127	similar to preprotein translocase	0.015
Cbl	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.015
Smap2	small ArfGAP2	0.015
Cd38	CD38 molecule	0.015
Grm7	glutamate receptor, metabotropic 7	0.015
Stx2	syntaxin 2	0.015
Gja5	gap junction protein, alpha 5	0.015
Gas7	growth arrest specific 7	0.015
Itgb7	integrin, beta 7	0.015
Nell1	NEL-like 1 (chicken)	0.015
Rhd	Rh blood group, D antigen	0.015
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.015
Ptprr	protein tyrosine phosphatase, receptor type, R	0.015
Mmp12	matrix metallopeptidase 12	0.015
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.014
Ptpn18	protein tyrosine phosphatase, non-receptor type 18	0.014
Rin1	Ras and Rab interactor 1	0.014
Plcb1	phospholipase C, beta 1 (phosphoinositide-specific)	0.014
Adrb2	adrenergic, beta-2-, receptor, surface	0.014
Mmp2	matrix metallopeptidase 2	0.014
Hpca	hippocalcin	0.014
Map3k9	mitogen-activated protein kinase kinase kinase 9	0.014
Stxbp1	syntaxin binding protein 1	0.014
Alox5	arachidonate 5-lipoxygenase	0.014
Pgr	progesterone receptor	0.014
Nell2	NEL-like 2 (chicken)	0.014
Igh-6	immunoglobulin heavy chain 6	0.014
LOC100364854	similar to RIKEN cDNA A430107P09 gene-like	0.014
Rab38	RAB38, member RAS oncogene family	0.014
Egfl8	EGF-like-domain, multiple 8	0.014
Csk	c-src tyrosine kinase	0.014
Fam126b	family with sequence similarity 126, member B	0.014
Cyp3a23/3a1	cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1	0.014
Kcnh1	potassium voltage-gated channel, subfamily H (eag-related), member 1	0.014
Foxp1	forkhead box P1	0.014
Wt1	Wilms tumor 1	0.014
Gria2	glutamate receptor, ionotropic, AMPA 2	0.013
Olr1413	olfactory receptor 1413	0.013
Sla	src-like adaptor	0.013
Rasgrp1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	0.013
Met	met proto-oncogene	0.013
Gata6	GATA binding protein 6	0.013
Rab15	RAB15, member RAS oncogene family	0.013
Celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.013
Adra1b	adrenergic, alpha-1B-, receptor	0.013
Snrk	SNF related kinase	0.013
Nxph1	neurexophilin 1	0.013
Galm	galactose mutarotase (aldose 1-epimerase)	0.013
Rims1	regulating synaptic membrane exocytosis 1	0.013
Olr1697	olfactory receptor 1697	0.013
Matk	megakaryocyte-associated tyrosine kinase	0.013
Glp1r	glucagon-like peptide 1 receptor	0.013
Icam1	intercellular adhesion molecule 1	0.013
Arl11	ADP-ribosylation factor-like 11	0.013
Cadps2	Ca++-dependent secretion activator 2	0.013
Msl1	male-specific lethal 1 homolog (Drosophila)	0.013
Tcrb	T-cell receptor beta chain	0.013
Jag2	jagged 2	0.012
Slit1	slit homolog 1 (Drosophila)	0.012
Zh16	ZH16 protein	0.012
Synpo	synaptopodin	0.012
Map2	microtubule-associated protein 2	0.012
Pawr	PRKC, apoptosis, WT1, regulator	0.012
Dpep1	dipeptidase 1 (renal)	0.012
Myt1l	myelin transcription factor 1-like	0.012
Hspa13	heat shock protein 13	0.012
Srebf1	sterol regulatory element binding transcription factor 1	0.012
Epas1	endothelial PAS domain protein 1	0.012
Phemx	pan hematopoietic expression	0.012
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.012
Tcf4	transcription factor 4	0.012
Olr1523	olfactory receptor 1523	0.012
Pik3cd	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.012
Atp2b3	ATPase, Ca++ transporting, plasma membrane 3	0.012
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.012
Cd53	Cd53 molecule	0.012
Grik5	glutamate receptor, ionotropic, kainate 5	0.012
Lbr	lamin B receptor	0.012
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.012
Ncf4	neutrophil cytosolic factor 4	0.012
Camkk2	calcium/calmodulin-dependent protein kinase kinase 2, beta	0.012
Ar	androgen receptor	0.012
Padi2	peptidyl arginine deiminase, type II	0.012
Sox4	SRY (sex determining region Y)-box 4	0.012
LOC100362155	cysteine and histidine rich 1	0.012
Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5	0.012
Itga6	integrin, alpha 6	0.012
Dpysl4	dihydropyrimidinase-like 4	0.012
Odz2	odz, odd Oz/ten-m homolog 2 (Drosophila)	0.012
Slc20a2	solute carrier family 20 (phosphate transporter), member 2	0.012
Camkv	CaM kinase-like vesicle-associated	0.011
Ddn	dendrin	0.011
Pcdhga11	protocadherin gamma subfamily A, 11	0.011
Cdc42bpb	CDC42 binding protein kinase beta (DMPK-like)	0.011
Tbc1d10c	TBC1 domain family, member 10C	0.011
Neurl3	neuralized homolog 3 (Drosophila)	0.011
Rps6ka1	ribosomal protein S6 kinase polypeptide 1	0.011
Phlpp1	PH domain and leucine rich repeat protein phosphatase 1	0.011
Plek	pleckstrin	0.011
Epha2	Eph receptor A2	0.011
Itpr2	inositol 1,4,5-triphosphate receptor, type 2	0.011
Dclk1	doublecortin-like kinase 1	0.011
Gcm1	glial cells missing homolog 1 (Drosophila)	0.011
Flt1	FMS-related tyrosine kinase 1	0.011
Tlr4	toll-like receptor 4	0.011
Irf6	interferon regulatory factor 6	0.011
Ceacam10	carcinoembryonic antigen-related cell adhesion molecule 10	0.011
Tlr2	toll-like receptor 2	0.011
Camk2d	calcium/calmodulin-dependent protein kinase II delta	0.011
Abcc8	ATP-binding cassette, subfamily C (CFTR/MRP), member 8	0.011
Galntl1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1	0.011
LOC683626	similar to limb-bud and heart	0.011
Slc1a1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	0.011
Ctnnd2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	0.011
Pou3f1	POU class 3 homeobox 1	0.011
Fam26f	family with sequence similarity 26, member F	0.011
Map3k3	mitogen activated protein kinase kinase kinase 3	0.011
Kcng3	potassium voltage-gated channel, subfamily G, member 3	0.011
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.011
Olr37	olfactory receptor 37	0.011
Itpr1	inositol 1,4,5-triphosphate receptor, type 1	0.011
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.010
C5ar1	complement component 5a receptor 1	0.010
Olr1470	olfactory receptor 1470	0.010
Dlgap2	discs, large (Drosophila) homolog-associated protein 2	0.010
Gsk3b	glycogen synthase kinase 3 beta	0.010
Ttyh3	tweety homolog 3 (Drosophila)	0.010
Vars	valyl-tRNA synthetase	0.010
Slc22a23	solute carrier family 22, member 23	0.010
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.010
Lsamp	limbic system-associated membrane protein	0.010
Tead3	TEA domain family member 3	0.010
RT1-DMa	RT1 class II, locus DMa	0.010
Irf1	interferon regulatory factor 1	0.010
Cybb	cytochrome b-245, beta polypeptide	0.010
Git1	G protein-coupled receptor kinase interacting ArfGAP 1	0.010
Neurod2	neurogenic differentiation 2	0.010
Nrn1	neuritin 1	0.010
Sash3	SAM and SH3 domain containing 3	0.010
Scarb1	scavenger receptor class B, member 1	0.010
Olfml2b	olfactomedin-like 2B	0.010
Apol3	apolipoprotein L, 3	0.010
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.010
RGD1564163	similar to RIKEN cDNA 1700025K23	0.010
Prkci	protein kinase C, iota	0.010
Nr2f6	nuclear receptor subfamily 2, group F, member 6	0.010
Kcnd3	potassium voltage-gated channel, Shal-related subfamily, member 3	0.010
Clcn3	chloride channel 3	0.010