IMP
Process View
proteasome mediated ubiquitin dependent protein catabolic process
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "proteasome mediated ubiquitin dependent protein catabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Psma5 | proteasome (prosome, macropain) subunit, alpha type 5 | 0.995 | Yeast | |
| Psma7 | proteasome (prosome, macropain) subunit, alpha type 7 | 0.975 | Yeast | |
| Psma3 | proteasome (prosome, macropain) subunit, alpha type 3 | 0.949 | Yeast | |
| Psmc2 | proteasome (prosome, macropain) 26S subunit, ATPase 2 | 0.814 | ||
| Psmb3 | proteasome (prosome, macropain) subunit, beta type 3 | 0.797 | Yeast | |
| Psma4 | proteasome (prosome, macropain) subunit, alpha type 4 | 0.793 | Yeast | |
| Psma2 | proteasome (prosome, macropain) subunit, alpha type 2 | 0.467 | Yeast | |
| Psmb4 | proteasome (prosome, macropain) subunit, beta type 4 | 0.391 | Yeast | |
| Psmb10 | proteasome (prosome, macropain) subunit, beta type 10 | 0.372 | Yeast | |
| Psmc1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 0.337 | ||
| Psmb2 | proteasome (prosome, macropain) subunit, beta type 2 | 0.334 | Yeast | |
| Psmc4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.292 | ||
| Psmb6 | proteasome (prosome, macropain) subunit, beta type 6 | 0.287 | Yeast | |
| Psmb1 | proteasome (prosome, macropain) subunit, beta type 1 | 0.232 | Yeast | |
| Psmd6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.196 | ||
| Psmb8 | proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) | 0.187 | Yeast | |
| Dnaja1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.168 | Yeast | |
| Psmb7 | proteasome (prosome, macropain) subunit, beta type 7 | 0.164 | Yeast | |
| Ufd1l | ubiquitin fusion degradation 1 like (yeast) | 0.143 | ||
| Psmb9 | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) | 0.123 | Yeast | |
| Psmd7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.116 | ||
| Psme2 | proteasome (prosome, macropain) activator subunit 2 | 0.098 | ||
| Mgat2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | 0.080 | ||
| Ppp1r2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.066 | ||
| Ptges3 | prostaglandin E synthase 3 (cytosolic) | 0.057 | ||
| Rgs19 | regulator of G-protein signaling 19 | 0.056 | ||
| Arf1 | ADP-ribosylation factor 1 | 0.056 | ||
| Rbbp7 | retinoblastoma binding protein 7 | 0.052 | ||
| Ube2c | ubiquitin-conjugating enzyme E2C | 0.052 | ||
| Sec61a1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.049 | ||
| Ube2i | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.047 | ||
| Dnaja2 | DnaJ (Hsp40) homolog, subfamily A, member 2 | 0.043 | Yeast | |
| Ppp1cb | protein phosphatase 1, catalytic subunit, beta isoform | 0.043 | ||
| Pdia4 | protein disulfide isomerase family A, member 4 | 0.040 | ||
| Cand1 | cullin-associated and neddylation-dissociated 1 | 0.040 | ||
| Cnbp | CCHC-type zinc finger, nucleic acid binding protein | 0.037 | ||
| Pomp | proteasome maturation protein | 0.036 | ||
| Foxm1 | forkhead box M1 | 0.035 | ||
| LOC100364212 | heterogeneous nuclear ribonucleoprotein K-like | 0.035 | ||
| Hspa5 | heat shock protein 5 | 0.032 | Yeast | |
| Psmc5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 0.032 | Human Yeast | |
| Ghitm | growth hormone inducible transmembrane protein | 0.029 | ||
| Rab11a | RAB11a, member RAS oncogene family | 0.028 | ||
| Eef2 | eukaryotic translation elongation factor 2 | 0.028 | ||
| Nsfl1c | NSFL1 (p97) cofactor (p47) | 0.027 | ||
| Btg1 | B-cell translocation gene 1, anti-proliferative | 0.026 | ||
| Pak2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.024 | ||
| Psmd13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 0.024 | ||
| Txnl1 | thioredoxin-like 1 | 0.024 | ||
| Kif22 | kinesin family member 22 | 0.023 | ||
| Psmc3 | proteasome (prosome, macropain) 26S subunit, ATPase 3 | 0.023 | ||
| Mapre1 | microtubule-associated protein, RP/EB family, member 1 | 0.023 | ||
| Cdca3 | cell division cycle associated 3 | 0.023 | ||
| Ccnb1 | cyclin B1 | 0.022 | ||
| Plk1 | polo-like kinase 1 (Drosophila) | 0.021 | Human Rat | |
| Ifrd1 | interferon-related developmental regulator 1 | 0.021 | ||
| Psmd4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.020 | ||
| Hsp90b1 | heat shock protein 90, beta, member 1 | 0.020 | Human | |
| Phax | phosphorylated adaptor for RNA export | 0.020 | ||
| LOC687711 | similar to small nuclear ribonucleoprotein D3 | 0.020 | ||
| Dnm1l | dynamin 1-like | 0.019 | ||
| Slc35b1 | solute carrier family 35, member B1 | 0.018 | ||
| LOC362855 | P55 | 0.018 | ||
| Syngr2 | synaptogyrin 2 | 0.017 | ||
| Gopc | golgi associated PDZ and coiled-coil motif containing | 0.017 | ||
| Vcp | valosin-containing protein | 0.016 | ||
| Ppp1cc | protein phosphatase 1, catalytic subunit, gamma isoform | 0.016 | Yeast | |
| Eif5a | eukaryotic translation initiation factor 5A | 0.015 | ||
| Rpl36 | ribosomal protein L36 | 0.015 | ||
| Stx12 | syntaxin 12 | 0.015 | ||
| Manf | mesencephalic astrocyte-derived neurotrophic factor | 0.015 | ||
| Thoc7 | THO complex 7 homolog (Drosophila) | 0.015 | ||
| Rbm8a | RNA binding motif protein 8A | 0.014 | ||
| Top2a | topoisomerase (DNA) II alpha | 0.014 | ||
| Ube2d2 | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | 0.014 | ||
| Bub1b | budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) | 0.014 | ||
| Dnajb11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.014 | ||
| Cops7a | COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis) | 0.013 | ||
| Akt2 | v-akt murine thymoma viral oncogene homolog 2 | 0.013 | ||
| Zfand5 | zinc finger, AN1-type domain 5 | 0.013 | ||
| Traf4af1 | TRAF4 associated factor 1 | 0.013 | ||
| Psmd8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 0.012 | ||
| Higd1a | HIG1 hypoxia inducible domain family, member 1A | 0.012 | ||
| Cmtm6 | CKLF-like MARVEL transmembrane domain containing 6 | 0.012 | ||
| Tomm20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.012 | ||
| Psmd14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.011 | ||
| LOC100365106 | rCG32755-like | 0.011 | ||
| Arf4 | ADP-ribosylation factor 4 | 0.011 | ||
| Cops2 | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 0.011 | ||
| Canx | calnexin | 0.011 | ||
| Rad23b | RAD23 homolog B (S. cerevisiae) | 0.011 | Human | |
| Psma6 | proteasome (prosome, macropain) subunit, alpha type 6 | 0.011 | Yeast | |
| Ppp2ca | protein phosphatase 2, catalytic subunit, alpha isoform | 0.011 | ||
| Pdrg1 | p53 and DNA damage regulated 1 | 0.011 | ||
| Sfpq | splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) | 0.010 | ||
| Rnaseh2a | ribonuclease H2, subunit A | 0.010 | ||
| Ube2a | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 0.010 | ||
| Dnajc3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.010 | ||
| Cd82 | Cd82 molecule | 0.010 | ||
| Sumo1 | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 0.010 | Human | |
| Ppm1a | protein phosphatase 1A, magnesium dependent, alpha isoform | 0.010 | ||
| Tcta | T-cell leukemia translocation altered gene | 0.010 | ||
| Atp6v1g1 | ATPase, H transporting, lysosomal V1 subunit G1 | 0.010 |