IMP

Process View

Rattus norvegicus

27 genes annotated in rat

response to morphine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to morphine"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to morphine" (in gray)

Name	Description	Probability	Func Analog Organism
RT1-Ba	RT1 class II, locus Ba	0.345
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.101
Cxcl2	chemokine (C-X-C motif) ligand 2	0.091
Ccl2	chemokine (C-C motif) ligand 2	0.082
Ccl3	chemokine (C-C motif) ligand 3	0.063	Rat
Sparc	secreted protein, acidic, cysteine-rich (osteonectin)	0.052
Zfp36	zinc finger protein 36	0.044
Ccl4	chemokine (C-C motif) ligand 4	0.041	Rat
Zyx	zyxin	0.040
Drd1a	dopamine receptor D1A	0.040
Syn2	synapsin II	0.038
Il1a	interleukin 1 alpha	0.037
Opcml	opioid binding protein/cell adhesion molecule-like	0.036
Neurl3	neuralized homolog 3 (Drosophila)	0.036
Gpr88	G-protein coupled receptor 88	0.033
Adora2a	adenosine A2a receptor	0.032
Hrh4	histamine receptor H4	0.032
Hpca	hippocalcin	0.031
Tacr1	tachykinin receptor 1	0.030
Junb	jun B proto-oncogene	0.030
Sdcbp2	syndecan binding protein (syntenin) 2	0.029
Vat1	vesicle amine transport protein 1 homolog (T californica)	0.028
Jun	Jun oncogene	0.027
RGD1564664	similar to LOC387763 protein	0.027
Nos1ap	nitric oxide synthase 1 (neuronal) adaptor protein	0.026
Svs3a	seminal vesicle secretory protein 3A	0.026
Gad1	glutamate decarboxylase 1	0.026
Sstr2	somatostatin receptor 2	0.024	Rat
Cxcl6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.024
Nmbr	neuromedin B receptor	0.024
Socs3	suppressor of cytokine signaling 3	0.024
Dusp4	dual specificity phosphatase 4	0.023
Sst	somatostatin	0.023
F2rl1	coagulation factor II (thrombin) receptor-like 1	0.022
Cd74	Cd74 molecule, major histocompatibility complex, class II invariant chain	0.022
Il10	interleukin 10	0.022
Drd2	dopamine receptor D2	0.021	Mouse
Vip	vasoactive intestinal peptide	0.021
Egr1	early growth response 1	0.021
Gabrb1	gamma-aminobutyric acid (GABA) A receptor, beta 1	0.021
Lrp3	low density lipoprotein receptor-related protein 3	0.021
Vom2r53	vomeronasal 2 receptor, 53	0.021
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.020
Mmp10	matrix metallopeptidase 10	0.020
Kcng2	potassium voltage-gated channel, subfamily G, member 2	0.020
Camkv	CaM kinase-like vesicle-associated	0.020
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.020
Btg2	BTG family, member 2	0.020
Kcnc2	potassium voltage gated channel, Shaw-related subfamily, member 2	0.020
Itgam	integrin, alpha M	0.020
Il1b	interleukin 1 beta	0.019
Scn10a	sodium channel, voltage-gated, type X, alpha subunit	0.019
Cxcl3	chemokine (C-X-C motif) ligand 3	0.019
Calca	calcitonin-related polypeptide alpha	0.019
Grm1	glutamate receptor, metabotropic 1	0.019
Chrna4	cholinergic receptor, nicotinic, alpha 4	0.019
LOC100364212	heterogeneous nuclear ribonucleoprotein K-like	0.019
Serpinb2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.018
Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.018
Csrp1	cysteine and glycine-rich protein 1	0.018
Grik1	glutamate receptor, ionotropic, kainate 1	0.018
Rgs1	regulator of G-protein signaling 1	0.018
B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	0.018
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.018
Il1rn	interleukin 1 receptor antagonist	0.018
Cxcl10	chemokine (C-X-C motif) ligand 10	0.018
Map3k11	mitogen-activated protein kinase kinase kinase 11	0.017
Calb1	calbindin 1	0.017
Dusp1	dual specificity phosphatase 1	0.017
Chga	chromogranin A	0.017
Fcgr3a	Fc fragment of IgG, low affinity IIIa, receptor	0.017
Neu2	sialidase 2 (cytosolic sialidase)	0.017
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.016
Glra2	glycine receptor, alpha 2	0.016
Shank2	SH3 and multiple ankyrin repeat domains 2	0.016
Il1r1	interleukin 1 receptor, type I	0.016
Ciita	class II, major histocompatibility complex, transactivator	0.016
Rgs4	regulator of G-protein signaling 4	0.016
Nrxn3	neurexin 3	0.016
Syt4	synaptotagmin IV	0.016
Tcf4	transcription factor 4	0.016
Grin2b	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.016
Adam2	ADAM metallopeptidase domain 2	0.016
Kl	Klotho	0.015
Slc16a8	solute carrier family 16, member 8 (monocarboxylic acid transporter 3)	0.015
Rpe65	retinal pigment epithelium 65	0.015
Psg19	pregnancy specific glycoprotein 19	0.015
Fshb	follicle stimulating hormone, beta polypeptide	0.015
Atf3	activating transcription factor 3	0.015	Rat
Ccnl1	cyclin L1	0.015
Cd37	CD37 molecule	0.015
Plaur	plasminogen activator, urokinase receptor	0.015
Apba2	amyloid beta (A4) precursor protein-binding, family A, member 2	0.015
Tgm1	transglutaminase 1, K polypeptide	0.015
Mog	myelin oligodendrocyte glycoprotein	0.015
P2ry14	purinergic receptor P2Y, G-protein coupled, 14	0.015
Kif6	kinesin family member 6	0.015
Gng7	guanine nucleotide binding protein (G protein), gamma 7	0.015
Kcnv1	potassium channel, subfamily V, member 1	0.015
Ptpn5	protein tyrosine phosphatase, non-receptor type 5	0.014
Plp1	proteolipid protein 1	0.014
Nrg1	neuregulin 1	0.014
Slco2b1	solute carrier organic anion transporter family, member 2b1	0.014
Cort	cortistatin	0.014
Sec1	secretory blood group 1	0.014
Pax6	paired box 6	0.014
Cntn3	contactin 3 (plasmacytoma associated)	0.014
Impg2	interphotoreceptor matrix proteoglycan 2	0.014
Fgfr1	Fibroblast growth factor receptor 1	0.014
Ptafr	platelet-activating factor receptor	0.014
Oprm1	opioid receptor, mu 1	0.014
Ccl22	chemokine (C-C motif) ligand 22	0.014
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.014
Npy5r	neuropeptide Y receptor Y5	0.014	Rat
Mas1	MAS1 oncogene	0.014
Gcnt3	glucosaminyl (N-acetyl) transferase 3, mucin type	0.014
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.014
Dio3	deiodinase, iodothyronine, type III	0.014
Dbc1	deleted in bladder cancer 1 (human)	0.014
Phox2a	paired-like homeobox 2a	0.014
Taok2	TAO kinase 2	0.014
Egr2	early growth response 2	0.014
LOC100363783	rCG53773-like	0.013
Grp	gastrin releasing peptide	0.013
Fgf2	fibroblast growth factor 2	0.013
Nr4a3	nuclear receptor subfamily 4, group A, member 3	0.013
Atp12a	ATPase, H+/K+ transporting, nongastric, alpha polypeptide	0.013
Il17f	interleukin 17F	0.013
Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)	0.013
Tgfb1	transforming growth factor, beta 1	0.013
Olr1078	olfactory receptor 1078	0.013
Snap91	synaptosomal-associated protein 91	0.013
Ckmt1	creatine kinase, mitochondrial 1	0.013
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.013
Chrna3	cholinergic receptor, nicotinic, alpha 3	0.013
Slc15a3	solute carrier family 15, member 3	0.013
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.013
N5	DNA binding protein N5	0.013
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.013
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.013
Gzmk	granzyme K	0.013
Mcpt8	mast cell protease 8	0.013
Lrfn2	leucine rich repeat and fibronectin type III domain containing 2	0.012
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, gamma 1	0.012
Dlgap3	discs, large (Drosophila) homolog-associated protein 3	0.012
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.012
Bcan	brevican	0.012
Syt13	synaptotagmin XIII	0.012
Psp	parotid secretory protein	0.012
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.012
Grm6	glutamate receptor, metabotropic 6	0.012
Slc7a3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	0.012
LOC685020	similar to paired immunoglobin-like type 2 receptor alpha	0.012
Cnp	2',3'-cyclic nucleotide 3' phosphodiesterase	0.012
Slc8a3	solute carrier family 8 (sodium/calcium exchanger), member 3	0.012
Gabra5	gamma-aminobutyric acid (GABA) A receptor, alpha 5	0.012
Arpp21	cAMP-regulated phosphoprotein 21	0.012
LRRTM1	leucine rich repeat transmembrane neuronal 1	0.012
Slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.012
Sorcs3	sortilin-related VPS10 domain containing receptor 3	0.012
Txnrd1	thioredoxin reductase 1	0.012
Arl11	ADP-ribosylation factor-like 11	0.012
Galp	galanin-like peptide	0.012
RGD1560559	similar to RIKEN cDNA 2310042E22	0.012
Chl1	cell adhesion molecule with homology to L1CAM	0.012
Slfn3	schlafen 3	0.012
Foxe1	forkhead box E1 (thyroid transcription factor 2)	0.012
Chat	choline acetyltransferase	0.012
Il1r2	interleukin 1 receptor, type II	0.012
Homer3	homer homolog 3 (Drosophila)	0.012
Acmsd	aminocarboxymuconate semialdehyde decarboxylase	0.012
Cd2	Cd2 molecule	0.011
Kcnb2	potassium voltage gated channel, Shab-related subfamily, member 2	0.011
Glra1	glycine receptor, alpha 1	0.011
Nmur2	neuromedin U receptor 2	0.011
Crisp2	cysteine-rich secretory protein 2	0.011
Plek	pleckstrin	0.011
Gnb2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.011
Ccl20	chemokine (C-C motif) ligand 20	0.011	Rat
Pcdhb12	protocadherin beta 12	0.011
LOC290595	hypothetical gene supported by AF152002	0.011
Slc9a5	solute carrier family 9 (sodium/hydrogen exchanger), member 5	0.011
Ddr1	discoidin domain receptor tyrosine kinase 1	0.011
LOC24906	RoBo-1	0.011
Dlx5	distal-less homeobox 5	0.011
Rasal1	RAS protein activator like 1 (GAP1 like)	0.011
Hes2	hairy and enhancer of split 2 (Drosophila)	0.011
Adrb1	adrenergic, beta-1-, receptor	0.011
Rras	Harvey rat sarcoma virus oncogene, subgroup R	0.011
Sval2	seminal vesicle antigen-like 2	0.011
Klf4	Kruppel-like factor 4 (gut)	0.011
Ch25h	cholesterol 25-hydroxylase	0.011
Kcnj16	potassium inwardly-rectifying channel, subfamily J, member 16	0.011
Cpne9	copine family member IX	0.011
Mapk8ip2	mitogen-activated protein kinase 8 interacting protein 2	0.011
Acr	acrosin	0.011
Lect1	leukocyte cell derived chemotaxin 1	0.011
Cckar	cholecystokinin A receptor	0.011
Olr1641	olfactory receptor 1641	0.011
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.011
Aldh6a1	aldehyde dehydrogenase 6 family, member A1	0.011
Fcgr1a	Fc fragment of IgG, high affinity Ia, receptor (CD64)	0.011
Cgm4	carcinoembryonic antigen gene family 4	0.011
Tas2r107	taste receptor, type 2, member 107	0.011
Myod1	myogenic differentiation 1	0.011
Adam3a	ADAM metallopeptidase domain 3A (cyritestin 1)	0.011
Plau	plasminogen activator, urokinase	0.011
Chrm1	cholinergic receptor, muscarinic 1	0.011
Aqp2	aquaporin 2 (collecting duct)	0.011
Ltbr	lymphotoxin beta receptor (TNFR superfamily, member 3)	0.011
Tfec	transcription factor EC	0.011
Ctxn1	cortexin 1	0.011
Hck	hemopoietic cell kinase	0.010
Sstr1	somatostatin receptor 1	0.010
Hcn1	hyperpolarization-activated cyclic nucleotide-gated potassium channel 1	0.010
Usp25	ubiquitin specific peptidase 25	0.010
Arc	activity-regulated cytoskeleton-associated protein	0.010
Tas2r105	taste receptor, type 2, member 105	0.010
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.010
Epha5	EphA5	0.010
Cadps	Ca++-dependent secretion activator	0.010
RGD1306474	similar to RIKEN cDNA 9530003J23	0.010
Mepe	matrix extracellular phosphoglycoprotein	0.010
Cd247	Cd247 molecule	0.010
Kcnq3	potassium voltage-gated channel, KQT-like subfamily, member 3	0.010
Napsa	napsin A aspartic peptidase	0.010
Lmna	lamin A	0.010
RGD1308350	similar to hypothetical protein MGC13251	0.010
Tlr2	toll-like receptor 2	0.010	Rat
Il8rb	interleukin 8 receptor, beta	0.010
Cd46	CD46 molecule, complement regulatory protein	0.010
Tagln3	transgelin 3	0.010
Nell1	NEL-like 1 (chicken)	0.010
Gzmm	granzyme M (lymphocyte met-ase 1)	0.010
Csf1	colony stimulating factor 1 (macrophage)	0.010
Nrgn	neurogranin	0.010
Prdm2	PR domain containing 2, with ZNF domain	0.010