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Process View

Danio rerio

6 genes annotated in zebrafish

t cell differentiation

The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "t cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "t cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
cmyb	transcription factor cmyb	0.969	Human
bmp2b	bone morphogenetic protein 2b	0.557
runx2a	runt-related transcription factor 2a	0.555	Mouse
runx1	runt-related transcription factor 1	0.340
ptger4a	prostaglandin E receptor 4 (subtype EP4) a	0.336
lef1	lymphocyte enhancer binding factor 1	0.285	Mouse
cdh1	cadherin 1, epithelial	0.243
kita	kit receptor a	0.240	Mouse
fgf3	fibroblast growth factor 3	0.223
cd247l	CD247 antigen like	0.211
runx3	runt-related transcription factor 3	0.198
il7r	interleukin 7 receptor	0.186
fgf4	fibroblast growth factor 4	0.182
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.180
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.173
foxi1	forkhead box I1	0.170
notch3	notch homolog 3	0.166
foxa1	forkhead box A1	0.148
jak3	Janus kinase 3 (a protein tyrosine kinase, leukocyte)	0.132
foxa2	forkhead box A2	0.126
npm4	nucleophosmin/nucleoplasmin, 4	0.122
gbx2	gastrulation brain homeo box 2	0.110
mmp9	matrix metalloproteinase 9	0.109
eomesb	eomesodermin homolog b	0.104	Human Mouse
rpl7a	ribosomal protein L7a	0.103
pax5	paired box gene 5	0.102
lck	lymphocyte-specific protein tyrosine kinase	0.100	Human Mouse
ccnd1	cyclin D1	0.097
fzd8a	frizzled homolog 8a	0.092	Mouse
fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.091
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.082
anxa1b	annexin A1b	0.081	Mouse
cd247	CD247 antigen	0.079
cd8a	CD8 antigen, alpha polypeptide	0.078	Mouse
cdx4	caudal type homeo box transcription factor 4	0.076
jak1	Janus kinase 1	0.072
tal1	T-cell acute lymphocytic leukemia 1	0.070
trim33	tripartite motif-containing 33	0.067
krt4	keratin 4	0.067
dlx6a	distal-less homeobox gene 6a	0.066
tbp	TATA box binding protein	0.064
mitfa	microphthalmia-associated transcription factor a	0.064
wnt1	wingless-type MMTV integration site family, member 1	0.061	Mouse
gata1a	GATA binding protein 1a	0.060
zgc:64115	zgc:64115	0.059
nitr9	novel immune-type receptor 9	0.057
rag1	recombination activating gene 1	0.056	Mouse
crfa31.2	IL-4RA-like protein 2	0.051
sox9b	SRY-box containing gene 9b	0.048
ihha	Indian hedgehog homolog a	0.048	Mouse
satb2	SATB homeobox 2	0.047
tyrobp	TYRO protein tyrosine kinase binding protein	0.046
fcer1gl	Fc receptor, IgE, high affinity I, gamma polypeptide like	0.044
jag1b	jagged 1b	0.044
kitlga	kit ligand a	0.043
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.041
lft1	lefty1	0.039
polr2d	polymerase (RNA) II (DNA directed) polypeptide D	0.038
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.037
lmo4a	LIM domain only 4a	0.036
eya2	eyes absent homolog 2 (Drosophila)	0.035
ighz	immunoglobulin heavy constant zeta	0.035
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.035
jag2	jagged 2	0.034	Human Mouse
tp63	tumor protein p63	0.034
egr2b	early growth response 2b	0.033
ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.033
ifnphi1	interferon phi 1	0.033
LOC100151531	zinc finger protein Gfi-1b-like	0.031
il4r	interleukin 4 receptor	0.030
ncor1	nuclear receptor co-repressor 1	0.029	Mouse
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.029
bcl2	B-cell leukemia/lymphoma 2	0.029	Mouse
id2a	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a	0.028
irx7	iroquois homeobox protein 7	0.028
dnmt4	DNA (cytosine-5-)-methyltransferase 4	0.027
csf1ra	colony stimulating factor 1 receptor, a	0.027
tshz1	teashirt family zinc finger 1	0.026
sox2	SRY-box containing gene 2	0.025
foxi2	forkhead box I2	0.025
id1	inhibitor of DNA binding 1	0.024
abcg2c	ATP-binding cassette, sub-family G (WHITE), member 2c	0.024
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.023
sox19a	SRY-box containing gene 19a	0.023
hlxb9la	homeo box HB9 like a	0.022
elk4	ELK4, ETS-domain protein	0.022
ihhb	Indian hedgehog homolog b	0.021	Mouse
gata3	GATA-binding protein 3	0.021	Mouse
ptch1	patched 1	0.021
rpl23a	ribosomal protein L23a	0.021
cdkn1a	cyclin-dependent kinase inhibitor 1A	0.020
dusp6	dual specificity phosphatase 6	0.020
wu:fb18f06	wu:fb18f06	0.020
dll4	delta-like 4 (Drosophila)	0.020
ccr9b	chemokine (C-C motif) receptor 9b	0.019
nrp2b	neuropilin 2b	0.019
LOC553366	hypothetical protein LOC553366	0.019
fgf20a	fibroblast growth factor 20a	0.018
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.017	Mouse
mst1rb	macrophage stimulating 1 receptor (c-met-related tyrosine kinase), b	0.017
hoxa2b	homeo box A2b	0.017
cdx1b	caudal type homeobox 1 b	0.016
gdf6a	growth differentiation factor 6a	0.015
abcg2a	ATP-binding cassette, sub-family G (WHITE), member 2a	0.015
ptger2a	prostaglandin E receptor 2a (subtype EP2)	0.015	Zebrafish
tyr	tyrosinase	0.015
sp7	Sp7 transcription factor	0.015
lycat	lysocardiolipin acyltransferase	0.015
otpa	orthopedia homolog a	0.014
hnf1ba	HNF1 homeobox Ba	0.014
zgc:101606	zgc:101606	0.014
cbfb	core-binding factor, beta subunit	0.014
ncoa2	nuclear receptor coactivator 2	0.014
znf703	zinc finger protein 703	0.014
anxa11a	annexin A11a	0.014
lmna	lamin A	0.013
zgc:158603	zgc:158603	0.013
pwp2h	PWP2 periodic tryptophan protein homolog (yeast)	0.012
stc1l	stanniocalcin 1, like	0.012
nme2b.1	non-metastatic cells 2b.1, protein (NM23B) expressed in	0.012
cnn3a	calponin 3, acidic a	0.012
il12bb	interleukin 12B, b	0.012
foxa3	forkhead box A3	0.012
id3	inhibitor of DNA binding 3	0.012
cfl1	cofilin 1 (non-muscle)	0.011
mych	myelocytomatosis oncogene homolog	0.011
dld	deltaD	0.011
rpe65b	retinal pigment epithelium-specific protein 65b	0.011
chd	chordin	0.011
rarga	retinoic acid receptor gamma a	0.011
flh	floating head	0.011
zgc:154068	zgc:154068	0.011
krt5	keratin 5	0.011
bmper	BMP binding endothelial regulator	0.010
icn	ictacalcin	0.010
zgc:162329	zgc:162329	0.010
hcst	hematopoietic cell signal transducer	0.010
ephb4b	eph receptor B4b	0.010
zgc:56382	zgc:56382	0.010
ednrb1	endothelin receptor B	0.010