The network for 'columnar cuboidal epithelial cell development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

columnar cuboidal epithelial cell development

The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.

Drosophila melanogaster
Name Description Probability Func Analog Organism
Rac1 CG2248 gene product from transcript CG2248-RA 1.000
par-1 CG8201 gene product from transcript CG8201-RA 1.000
Ras85D Ras oncogene at 85D 1.000
ttk tramtrack 1.000
Rala Ras-related protein 0.999
sqh spaghetti squash 0.999
ecd ecdysoneless 0.999
aop anterior open 0.999
Stat92E Signal-transducer and activator of transcription protein at 92E 0.996
dome domeless 0.995
yki yorkie 0.995
CG8155 CG8155 gene product from transcript CG8155-RA 0.992
Rho1 CG8416 gene product from transcript CG8416-RB 0.992
zip zipper 0.991
shg shotgun 0.990
Cortactin CG3637 gene product from transcript CG3637-RA 0.989
EcR Ecdysone receptor 0.989
cindr CIN85 and CD2AP orthologue 0.987
chic chickadee 0.987
hpo hippo 0.986
jing CG9397 gene product from transcript CG9397-RI 0.985
BicD Bicaudal D 0.985
mbc myoblast city 0.984
shn schnurri 0.983
kug kugelei 0.982
ph-p polyhomeotic proximal 0.980
Rab5 Rab-protein 5 0.979
grk gurken 0.978
kibra kibra ortholog 0.978
N Notch 0.978
Egfr Epidermal growth factor receptor 0.977
Ets97D Ets at 97D 0.977
Pvr PDGF- and VEGF-receptor related 0.977
Pvf1 PDGF- and VEGF-related factor 1 0.976
Fas2 Fasciclin 2 0.976
phl pole hole 0.975
Ced-12 CG5336 gene product from transcript CG5336-RA 0.973
rhea CG6831 gene product from transcript CG6831-RA 0.970
Dhc64C Dynein heavy chain 64C 0.966
os outstretched 0.960
Hop Hsp70/Hsp90 organizing protein homolog 0.958
baz bazooka 0.956
cpb capping protein beta 0.956
pnt pointed 0.955
Krn Keren 0.954
14-3-3zeta CG17870 gene product from transcript CG17870-RB 0.946
ex expanded 0.944
rl rolled 0.943
ci cubitus interruptus 0.940
alpha-Cat alpha Catenin 0.938
Lis-1 Lissencephaly-1 0.937
orb oo18 RNA-binding protein 0.923
nudE CG8104 gene product from transcript CG8104-RB 0.913
Btk29A Btk family kinase at 29A 0.913
Shc SHC-adaptor protein 0.909
Ppcs Phosphopantothenoylcysteine synthetase 0.908
Mrtf Myocardin-related transcription factor 0.908
fz frizzled 0.895
vas vasa 0.895
Cbl CG7037 gene product from transcript CG7037-RB 0.894
ena enabled 0.889
srp serpent 0.886
hd humpty dumpty 0.879
kel kelch 0.877
spn-B spindle B 0.876
hep hemipterous 0.876
ik2 IkappaB kinase-like 2 0.873
hth homothorax 0.870
Rbf Retinoblastoma-family protein 0.870
Rheb CG1081 gene product from transcript CG1081-RA 0.868
par-6 CG5884 gene product from transcript CG5884-RA 0.862
wts warts 0.861
tj traffic jam 0.852
dsh dishevelled 0.846
brk brinker 0.835
ndl nudel 0.827
CycE Cyclin E 0.827
Vang Van Gogh 0.823
dia diaphanous 0.822
Myo31DF Myosin 31DF 0.805
E(z) Enhancer of zeste 0.804
sens senseless 0.803
fs(1)M3 female sterile (1) M3 0.799
puc puckered 0.796
S6k RPS6-p70-protein kinase 0.789
wg wingless 0.787
bbg big bang 0.785
slbo slow border cells 0.785
Tm1 Tropomyosin 1 0.785
shi shibire 0.781
Dad Daughters against dpp 0.770
emc extra macrochaetae 0.766
toc toucan 0.759
jar jaguar 0.755
exd extradenticle 0.747
tin tinman 0.747
LanB2 Laminin B2 0.743
Hrb27C Heterogeneous nuclear ribonucleoprotein at 27C 0.735
hh hedgehog 0.725
Ubx Ultrabithorax 0.717
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
pax2a paired box gene 2a 0.379
evx1 even-skipped homeobox 1 0.098
shha sonic hedgehog a 0.060
olig2 oligodendrocyte lineage transcription factor 2 0.032
nkx2.2a NK2 transcription factor related 2a 0.024
lhx1a LIM homeobox 1a 0.023
bmp2b bone morphogenetic protein 2b 0.020
dla deltaA 0.020
tbx2b T-box 2b 0.018
mnx1 motor neuron and pancreas homeobox 1 0.017
mib mind bomb 0.017
pou3f3a POU class 3 homeobox 3a 0.016
dlx2a distal-less homeobox gene 2a 0.014
neurod4 neurogenic differentiation 4 0.014
lhx2b LIM homeobox 2b 0.013
hoxb5b homeo box B5b 0.012
notch1a notch homolog 1a 0.012
barhl2 BarH-like 2 0.012
adcyap1r1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 0.012
hoxa4a homeo box A4a 0.011
mecom MDS1 and EVI1 complex locus 0.011
vsx1 visual system homeobox 1 homolog, chx10-like 0.011
flot1 flotillin 1 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.678
BMPR1A bone morphogenetic protein receptor, type IA 0.375
CCND1 cyclin D1 0.353
CTNND1 catenin (cadherin-associated protein), delta 1 0.292
RXRA retinoid X receptor, alpha 0.207
CDK6 cyclin-dependent kinase 6 0.130
CCND3 cyclin D3 0.122
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.083
BMPR1B bone morphogenetic protein receptor, type IB 0.073
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.072
CLOCK clock homolog (mouse) 0.067
MED25 mediator complex subunit 25 0.056
NCOA1 nuclear receptor coactivator 1 0.050
EGLN3 egl nine homolog 3 (C. elegans) 0.046
TARBP2 TAR (HIV-1) RNA binding protein 2 0.027
EIF2C2 eukaryotic translation initiation factor 2C, 2 0.023
NKX3-1 NK3 homeobox 1 0.021
NOG noggin 0.019
NCOA3 nuclear receptor coactivator 3 0.018
RB1 retinoblastoma 1 0.017
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.016
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.015
RUNX1 runt-related transcription factor 1 0.014
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.013
EIF2C1 eukaryotic translation initiation factor 2C, 1 0.011
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 0.011
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.011
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Mus musculus
Name Description Probability Func Analog Organism
Fgf8 fibroblast growth factor 8 0.969
Pax8 paired box gene 8 0.963
Foxc1 forkhead box C1 0.959
Sox9 SRY-box containing gene 9 0.957
Fgfr2 fibroblast growth factor receptor 2 0.953
Shh sonic hedgehog 0.943
Hand2 heart and neural crest derivatives expressed transcript 2 0.940
Hoxb3 homeobox B3 0.936
Rarb retinoic acid receptor, beta 0.929
Hoxa3 homeobox A3 0.916
Rarg retinoic acid receptor, gamma 0.881
Hoxa2 homeobox A2 0.874
Otx2 orthodenticle homolog 2 (Drosophila) 0.872
Hoxd3 homeobox D3 0.849
Bmp7 bone morphogenetic protein 7 0.836
Fgfr1 fibroblast growth factor receptor 1 0.836
Msx1 homeobox, msh-like 1 0.836
Bmp4 bone morphogenetic protein 4 0.826
Tcfap2a transcription factor AP-2, alpha 0.820
Hoxa5 homeobox A5 0.819
Sim1 single-minded homolog 1 (Drosophila) 0.812
Gli2 GLI-Kruppel family member GLI2 0.812
Pbx1 pre B-cell leukemia transcription factor 1 0.794
Gli3 GLI-Kruppel family member GLI3 0.790
Eya1 eyes absent 1 homolog (Drosophila) 0.790
Hand1 heart and neural crest derivatives expressed transcript 1 0.767
Tbx1 T-box 1 0.752
Hoxb5 homeobox B5 0.740
Hoxb6 homeobox B6 0.736
Dlx5 distal-less homeobox 5 0.620
Foxc2 forkhead box C2 0.613
Foxa2 forkhead box A2 0.602
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.600
Lhx1 LIM homeobox protein 1 0.589
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.572
Chrd chordin 0.568
Hoxb4 homeobox B4 0.559
Hoxa9 homeobox A9 0.548
Hes1 hairy and enhancer of split 1 (Drosophila) 0.491
Trp63 transformation related protein 63 0.481
Rara retinoic acid receptor, alpha 0.480
Emx1 empty spiracles homolog 1 (Drosophila) 0.465
Pax3 paired box gene 3 0.465
Hoxd9 homeobox D9 0.455
Hoxb9 homeobox B9 0.453
Wnt3a wingless-related MMTV integration site 3A 0.436
Hoxc5 homeobox C5 0.435
Pitx2 paired-like homeodomain transcription factor 2 0.429
Hoxa1 homeobox A1 0.424
Hoxa4 homeobox A4 0.399
Ednra endothelin receptor type A 0.386
Prrx1 paired related homeobox 1 0.386
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.384
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.360
Rxra retinoid X receptor alpha 0.350
Nkx6-1 NK6 homeobox 1 0.314
Fgf10 fibroblast growth factor 10 0.309
Ahr aryl-hydrocarbon receptor 0.296
Wnt4 wingless-related MMTV integration site 4 0.296
Sox2 SRY-box containing gene 2 0.291
Pax9 paired box gene 9 0.280
Pax2 paired box gene 2 0.276
Nkx2-2 NK2 transcription factor related, locus 2 (Drosophila) 0.273
Hoxc4 homeobox C4 0.272
Hoxc9 homeobox C9 0.258
Hoxd8 homeobox D8 0.256
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.248
Nog noggin 0.247
Pou3f3 POU domain, class 3, transcription factor 3 0.235
Sall3 sal-like 3 (Drosophila) 0.234
Hoxb2 homeobox B2 0.223
Hoxa11 homeobox A11 0.217
Hoxa13 homeobox A13 0.216
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.214
Fgf15 fibroblast growth factor 15 0.211
Alx4 aristaless-like homeobox 4 0.206
Pdx1 pancreatic and duodenal homeobox 1 0.198
Mesp1 mesoderm posterior 1 0.195
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.193
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.191
Edn3 endothelin 3 0.184
Gdnf glial cell line derived neurotrophic factor 0.182
Pthlh parathyroid hormone-like peptide 0.179
Pou3f4 POU domain, class 3, transcription factor 4 0.177
Ihh Indian hedgehog 0.174
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.174
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.173
Hoxc8 homeobox C8 0.170
Msx2 homeobox, msh-like 2 0.158
Per2 period homolog 2 (Drosophila) 0.155
Wnt1 wingless-related MMTV integration site 1 0.155
Foxf1a forkhead box F1a 0.152
Emx2 empty spiracles homolog 2 (Drosophila) 0.151
Hoxc6 homeobox C6 0.151
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.149
Hoxd13 homeobox D13 0.149
Smo smoothened homolog (Drosophila) 0.148
Twist2 twist homolog 2 (Drosophila) 0.146
Foxd2 forkhead box D2 0.143
Kl klotho 0.141
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism