The network for 'regulation of interferon alpha biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of interferon alpha biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-alpha.

Homo sapiens
Name Description Probability Func Analog Organism
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 1.000
MYD88 myeloid differentiation primary response gene (88) 0.999
TICAM2 toll-like receptor adaptor molecule 2 0.769
TLR2 toll-like receptor 2 0.342
LY86 lymphocyte antigen 86 0.330
BTK Bruton agammaglobulinemia tyrosine kinase 0.270
VNN2 vanin 2 0.208
CCR1 chemokine (C-C motif) receptor 1 0.180
FGL2 fibrinogen-like 2 0.168
RNASE6 ribonuclease, RNase A family, k6 0.146
TFEC transcription factor EC 0.133
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 0.129
IGSF6 immunoglobulin superfamily, member 6 0.114
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.109
CD86 CD86 molecule 0.106
TLR1 toll-like receptor 1 0.105
IRAK2 interleukin-1 receptor-associated kinase 2 0.082
TLR4 toll-like receptor 4 0.074
SYK spleen tyrosine kinase 0.069
CD163 CD163 molecule 0.065
CYBB cytochrome b-245, beta polypeptide 0.064
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.063
IRAK3 interleukin-1 receptor-associated kinase 3 0.060
EVI2B ecotropic viral integration site 2B 0.056
TLR7 toll-like receptor 7 0.051
TLR6 toll-like receptor 6 0.051
CLEC7A C-type lectin domain family 7, member A 0.049
EVI2A ecotropic viral integration site 2A 0.046
MS4A4A membrane-spanning 4-domains, subfamily A, member 4 0.042
LRMP lymphoid-restricted membrane protein 0.037
MARCH1 membrane-associated ring finger (C3HC4) 1 0.037
C3AR1 complement component 3a receptor 1 0.032
IRAK1 interleukin-1 receptor-associated kinase 1 0.031
MSR1 macrophage scavenger receptor 1 0.031
CCR2 chemokine (C-C motif) receptor 2 0.030
MS4A7 membrane-spanning 4-domains, subfamily A, member 7 0.028
SLC7A7 solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 0.028
CTSS cathepsin S 0.026
SLFN12 schlafen family member 12 0.025
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.023
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.023
GPR65 G protein-coupled receptor 65 0.022
IRF8 interferon regulatory factor 8 0.022
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.022
GPR18 G protein-coupled receptor 18 0.022
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 0.022
MNDA myeloid cell nuclear differentiation antigen 0.020
PIK3CG phosphoinositide-3-kinase, catalytic, gamma polypeptide 0.020
SELL selectin L 0.019
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.019
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.019
CD180 CD180 molecule 0.018
BLNK B-cell linker 0.018
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.017
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 0.017
PTAFR platelet-activating factor receptor 0.017
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.015
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.015
IRAK4 interleukin-1 receptor-associated kinase 4 0.015
IGJ immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides 0.015
CYTIP cytohesin 1 interacting protein 0.015
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.015
CYSLTR1 cysteinyl leukotriene receptor 1 0.015
SASH3 SAM and SH3 domain containing 3 0.014
AIM2 absent in melanoma 2 0.014
MCTP1 multiple C2 domains, transmembrane 1 0.014
FPR3 formyl peptide receptor 3 0.014
C17orf60 chromosome 17 open reading frame 60 0.014
GPR34 G protein-coupled receptor 34 0.013
IFIH1 interferon induced with helicase C domain 1 0.013
MR1 major histocompatibility complex, class I-related 0.013
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.013
TLR5 toll-like receptor 5 0.013
C13orf18 chromosome 13 open reading frame 18 0.013
RGS18 regulator of G-protein signaling 18 0.012
STAP1 signal transducing adaptor family member 1 0.012
CYTH4 cytohesin 4 0.012
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.011
CLEC4A C-type lectin domain family 4, member A 0.011
BST1 bone marrow stromal cell antigen 1 0.011
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 0.011
TLR8 toll-like receptor 8 0.011
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 0.011
SAMD9L sterile alpha motif domain containing 9-like 0.011
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.011
STAP2 signal transducing adaptor family member 2 0.010
IL1RAP interleukin 1 receptor accessory protein 0.010
BIN2 bridging integrator 2 0.010
CD1C CD1c molecule 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Siglece sialic acid binding Ig-like lectin E 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism