IMP
Process View
The network for 'alpha beta t cell differentiation involved in immune response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
alpha beta t cell differentiation involved in immune response
The process in which an antigenically naive alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| IL4R | interleukin 4 receptor | 0.999 | |
| LIN9 | lin-9 homolog (C. elegans) | 0.622 | |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.573 | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.544 | |
| IL2RG | interleukin 2 receptor, gamma | 0.445 | |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.397 | |
| NCOR2 | nuclear receptor corepressor 2 | 0.371 | |
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.285 | |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | 0.275 | |
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.243 | |
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.195 | |
| IL23A | interleukin 23, alpha subunit p19 | 0.164 | |
| RXRA | retinoid X receptor, alpha | 0.157 | |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.127 | |
| MED25 | mediator complex subunit 25 | 0.086 | |
| PDZD11 | PDZ domain containing 11 | 0.078 | |
| NLK | nemo-like kinase | 0.067 | |
| PPARA | peroxisome proliferator-activated receptor alpha | 0.052 | |
| LIN54 | lin-54 homolog (C. elegans) | 0.049 | |
| NCOA1 | nuclear receptor coactivator 1 | 0.048 | |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.043 | |
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.033 | |
| IL4 | interleukin 4 | 0.031 | |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.030 | |
| CD247 | CD247 molecule | 0.024 | |
| BCL3 | B-cell CLL/lymphoma 3 | 0.023 | |
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.021 | |
| RARA | retinoic acid receptor, alpha | 0.018 | |
| IL6R | interleukin 6 receptor | 0.018 | |
| PML | promyelocytic leukemia | 0.018 | |
| TMEM173 | transmembrane protein 173 | 0.013 | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.013 | |
| IL8 | interleukin 8 | 0.012 | |
| JUNB | jun B proto-oncogene | 0.012 | |
| PLXND1 | plexin D1 | 0.010 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 1.000 | |
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.997 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.997 | |
| Tnf | tumor necrosis factor | 0.996 | |
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.993 | |
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.991 | |
| Socs1 | suppressor of cytokine signaling 1 | 0.989 | |
| Cd40 | CD40 antigen | 0.986 | |
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.985 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.977 | |
| Lepr | leptin receptor | 0.977 | |
| Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.975 | |
| Bcl3 | B-cell leukemia/lymphoma 3 | 0.973 | |
| Il1r1 | interleukin 1 receptor, type I | 0.968 | |
| Jak2 | Janus kinase 2 | 0.957 | |
| Pax2 | paired box gene 2 | 0.954 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.948 | |
| Csf2rb2 | colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) | 0.947 | |
| Ifng | interferon gamma | 0.937 | |
| Socs3 | suppressor of cytokine signaling 3 | 0.934 | |
| Tbx3 | T-box 3 | 0.931 | |
| Stat5a | signal transducer and activator of transcription 5A | 0.917 | |
| Il4ra | interleukin 4 receptor, alpha | 0.870 | |
| Fas | Fas (TNF receptor superfamily member 6) | 0.868 | |
| Irf9 | interferon regulatory factor 9 | 0.851 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.829 | |
| Stat6 | signal transducer and activator of transcription 6 | 0.786 | |
| Cish | cytokine inducible SH2-containing protein | 0.739 | |
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.735 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.730 | |
| Igh | immunoglobulin heavy chain complex | 0.726 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.721 | |
| Stat2 | signal transducer and activator of transcription 2 | 0.708 | |
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.704 | |
| Lyz2 | lysozyme 2 | 0.698 | |
| Il10 | interleukin 10 | 0.684 | |
| Myd88 | myeloid differentiation primary response gene 88 | 0.665 | |
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.653 | |
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.644 | |
| Stat5b | signal transducer and activator of transcription 5B | 0.639 | |
| Icam1 | intercellular adhesion molecule 1 | 0.606 | |
| Irf1 | interferon regulatory factor 1 | 0.599 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.596 | |
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.591 | |
| Gata6 | GATA binding protein 6 | 0.590 | |
| Traf6 | TNF receptor-associated factor 6 | 0.588 | |
| Irf5 | interferon regulatory factor 5 | 0.586 | |
| Csf2rb | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.572 | |
| Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 0.564 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.559 | |
| Jag1 | jagged 1 | 0.557 | |
| Runx1 | runt related transcription factor 1 | 0.540 | |
| Wt1 | Wilms tumor 1 homolog | 0.524 | |
| Il10ra | interleukin 10 receptor, alpha | 0.512 | |
| Ccl7 | chemokine (C-C motif) ligand 7 | 0.511 | |
| Sfpi1 | SFFV proviral integration 1 | 0.469 | |
| Nf1 | neurofibromatosis 1 | 0.457 | |
| Ccl12 | chemokine (C-C motif) ligand 12 | 0.455 | |
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.445 | |
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.418 | |
| Batf | basic leucine zipper transcription factor, ATF-like | 0.403 | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.398 | |
| Foxp3 | forkhead box P3 | 0.392 | |
| Jak3 | Janus kinase 3 | 0.378 | |
| Il6 | interleukin 6 | 0.373 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.369 | |
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.357 | |
| Selp | selectin, platelet | 0.355 | |
| Nos2 | nitric oxide synthase 2, inducible | 0.348 | |
| Rxra | retinoid X receptor alpha | 0.346 | |
| Il1b | interleukin 1 beta | 0.333 | |
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.323 | |
| Rarg | retinoic acid receptor, gamma | 0.312 | |
| Cd86 | CD86 antigen | 0.304 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.299 | |
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.295 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.294 | |
| Il4 | interleukin 4 | 0.292 | |
| Birc3 | baculoviral IAP repeat-containing 3 | 0.291 | |
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.281 | |
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.272 | |
| Ch25h | cholesterol 25-hydroxylase | 0.265 | |
| Hoxa1 | homeobox A1 | 0.262 | |
| Shh | sonic hedgehog | 0.261 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.261 | |
| Mmp9 | matrix metallopeptidase 9 | 0.260 | |
| Rc3h1 | RING CCCH (C3H) domains 1 | 0.260 | |
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.257 | |
| Irf4 | interferon regulatory factor 4 | 0.255 | |
| Pim1 | proviral integration site 1 | 0.254 | |
| Il17ra | interleukin 17 receptor A | 0.248 | |
| Il6st | interleukin 6 signal transducer | 0.245 | |
| Fgf10 | fibroblast growth factor 10 | 0.234 | |
| Irf7 | interferon regulatory factor 7 | 0.226 | |
| Prdm1 | PR domain containing 1, with ZNF domain | 0.220 | |
| Cd44 | CD44 antigen | 0.218 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.211 | |
| Nfkbie | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.194 | |
| Foxf1a | forkhead box F1a | 0.189 | |
| Atxn1 | ataxin 1 | 0.185 |